Contributions of the maternal oral and gut microbiome to placental microbial colonization in overweight and obese pregnant women

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Gomez Arango, Luisa F ^a,b   Barrett, Helen L ^a,b,c   McIntyre, H David ^a   Callaway, Leonie K ^a,b,c   Morrison, Mark ^a,b   Nitert, Marloes Dekker ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

ADULT; FEMALE; HUMAN; INTESTINE FLORA; METAGENOME; METAGENOMICS; MICROBIOLOGY; MOUTH; OBESITY; PHYLOGENY; PLACENTA; PREGNANCY; PREGNANCY COMPLICATION; PROCEDURES;

ADULT; BIOMARKERS; FEMALE; GASTROINTESTINAL MICROBIOME; HUMANS; METAGENOME; METAGENOMICS; MOUTH; OBESITY; OVERWEIGHT; PHYLOGENY; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS;

EID: 85020636153     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-03066-4     Document Type: Article

References (53)

1. Gomez de Aguero, M. et al. The maternal microbiota drives early postnatal innate immune development. Science (New York, N.Y.) 351, 1296-1302, doi:10.1126/science.aad2571 (2016).
2. Fujimura, K. E. et al. Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation. 22, 1187-1191, doi:10.1038/nm.4176 (2016).
3. Ajslev, T. A., Andersen, C. S., Gamborg, M., Sorensen, T. I. & Jess, T. Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics. International journal of obesity (2005) 35, 522-529, doi:10.1038/ijo.2011.27 (2011).
4. Cox, L. M. et al. Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences. Cell 158, 705-721, doi:10.1016/j.cell.2014.05.052 (2014).
5. Collado, M. C., Rautava, S., Aakko, J., Isolauri, E. & Salminen, S. Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid. Scientific reports 6, 23129, doi:10.1038/srep23129 (2016).
6. Goldenberg, R. L., Culhane, J. F., Iams, J. D. & Romero, R. Epidemiology and causes of preterm birth. Lancet 371, 75-84, doi:10.1016/ s0140-6736(08)60074-4 (2008).
7. Perez, P. F. et al. Bacterial imprinting of the neonatal immune system: lessons from maternal cells? Pediatrics 119, e724-732, doi:10.1542/peds.2006-1649 (2007).
8. Fardini, Y., Chung, P., Dumm, R., Joshi, N. & Han, Y. W. Transmission of diverse oral bacteria to murine placenta: evidence for the oral microbiome as a potential source of intrauterine infection. Infection and immunity 78, 1789-1796, doi:10.1128/iai.01395-09 (2010).
9. Han, Y. W. et al. Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth. Infection and immunity 72, 2272-2279 (2004).
10. Aagaard, K. et al. The placenta harbors a unique microbiome. Science translational medicine 6, 237ra265, doi:10.1126/ scitranslmed.3008599 (2014).
11. Nitert, M. D. et al. SPRING: an RCT study of probiotics in the prevention of gestational diabetes mellitus in overweight and obese women. BMC pregnancy and childbirth 13, 50, doi:10.1186/1471-2393-13-50 (2013).
12. Prince, A. L. et al. The placental microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis. American journal of obstetrics and gynecology, doi:10.1016/j.ajog.2016.01.193 (2016).
13. Amarasekara, R., Jayasekara, R. W., Senanayake, H. & Dissanayake, V. H. Microbiome of the placenta in pre-eclampsia supports the role of bacteria in the multifactorial cause of pre-eclampsia. The journal of obstetrics and gynaecology research 41, 662-669, doi:10.1111/jog.12619 (2015).
14. Antony, K. M. et al. The preterm placental microbiome varies in association with excess maternal gestational weight gain. American journal of obstetrics and gynecology 212, 653.e651-616, doi:10.1016/j.ajog.2014.12.041 (2015).
15. Bassols, J. et al. Gestational Diabetes is associated with changes in Placental Microbiota and Microbiome. Pediatric research, doi:10.1038/pr.2016.155 (2016).
16. Lauder, A. P. et al. Comparison of placenta samples with contamination controls does not provide evidence for a distinct placenta microbiota. Microbiome 4, 29, doi:10.1186/s40168-016-0172-3 (2016).
17. Nasidze, I., Li, J., Quinque, D., Tang, K. & Stoneking, M. Global diversity in the human salivary microbiome. Genome research 19, 636-643, doi:10.1101/gr.084616.108 (2009).
18. Arumugam, M. et al. Enterotypes of the human gut microbiome. Nature 473, 174-180, doi:10.1038/nature09944 (2011).
19. Consortium, H. M. P. Structure, function and diversity of the healthy human microbiome. Nature 486, 207-214, doi:10.1038/ nature11234 (2012).
20. Wang, M., Ahrne, S., Jeppsson, B. & Molin, G. Comparison of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S rRNA genes. FEMS microbiology ecology 54, 219-231, doi:10.1016/j.femsec.2005.03.012 (2005).
21. Hayashi, H., Takahashi, R., Nishi, T., Sakamoto, M. & Benno, Y. Molecular analysis of jejunal, ileal, caecal and recto-sigmoidal human colonic microbiota using 16S rRNA gene libraries and terminal restriction fragment length polymorphism. Journal of medical microbiology 54, 1093-1101, doi:10.1099/jmm.0.45935-0 (2005).
22. Segata, N. et al. Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples. Genome biology 13, R42, doi:10.1186/gb-2012-13-6-r42 (2012).
23. Nardone, G. & Compare, D. The human gastric microbiota: Is it time to rethink the pathogenesis of stomach diseases? United European gastroenterology journal 3, 255-260, doi:10.1177/2050640614566846 (2015).
24. Kerr, C. A. et al. Early life events influence whole-of-life metabolic health via gut microflora and gut permeability. Critical reviews in microbiology 41, 326-340, doi:10.3109/1040841x.2013.837863 (2015).
25. Boutigny, H. et al. Oral Infections and Pregnancy: Knowledge of Gynecologists/Obstetricians, Midwives and Dentists. Oral health & preventive dentistry 14, 41-47, doi:10.3290/j.ohpd.a34376 (2016).
26. Mashima, I. & Nakazawa, F. The interaction between Streptococcus spp. and Veillonella tobetsuensis in the early stages of oral biofilm formation. Journal of bacteriology. doi:10.1128/jb.02512-14 (2015).
27. Nobbs, A. H., Lamont, R. J. & Jenkinson, H. F. Streptococcus adherence and colonization. Microbiology and molecular biology reviews: MMBR 73, 407-450, Table of Contents, doi:10.1128/mmbr.00014-09 (2009).
28. Okuda, T. K. E., Kawana, T., Saito, A., Okuda, K. & Ishihara, K. Synergy in biofilm formation between Fusobacterium nucleatum and Prevotella species. Anaerobe 18, 110-1116 (2012).
29. Backhed, F. et al. Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. Cell host & microbe 17, 690-703, doi:10.1016/j.chom.2015.04.004 (2015).
30. Do, T., Sheehy, E. C., Mulli, T., Hughes, F. & Beighton, D. Transcriptomic analysis of three Veillonella spp. present in carious dentine and in the saliva of caries-free individuals. Frontiers in cellular and infection microbiology 5, 25, doi:10.3389/fcimb.2015.00025 (2015).
31. Vaughan, O. R., Davies, K. L., Ward, J. W., de Blasio, M. J. & Fowden, A. L. A physiological increase in maternal cortisol alters uteroplacental metabolism in the pregnant ewe. The Journal of physiology 594, 6407-6418, doi:10.1113/jp272301 (2016).
32. van den Bogert, B., Meijerink, M., Zoetendal, E. G., Wells, J. M. & Kleerebezem, M. Immunomodulatory properties of Streptococcus and Veillonella isolates from the human small intestine microbiota. PLoS One 9, e114277, doi:10.1371/journal.pone.0114277 (2014).
33. Han, Y. W. et al. Term stillbirth caused by oral Fusobacterium nucleatum. Obstetrics and gynecology 115, 442-445, doi:10.1097/ AOG.0b013e3181cb9955 (2010).
34. Han, Y. W. et al. Transmission of an uncultivated Bergeyella strain from the oral cavity to amniotic fluid in a case of preterm birth. Journal of clinical microbiology 44, 1475-1483, doi:10.1128/jcm.44.4.1475-1483.2006 (2006).
35. Jimenez, E. et al. Is meconium from healthy newborns actually sterile? Research in microbiology 159, 187-193, doi:10.1016/j. resmic.2007.12.007 (2008).
36. Qin, J. et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464, 59-65, doi:10.1038/ nature08821 (2010).
37. Belda-Ferre, P. et al. The oral metagenome in health and disease. The ISME journal 6, 46-56, doi:10.1038/ismej.2011.85 (2012).
38. Nick Goeden, J. C. V. a. A. B. Placental tryptophan metabolism as a potential novel pathway for the developmental origins of mental diseaseS. Translational Developmental Psychiatry 1 (2013).
39. Sedlmayr, P., Blaschitz, A. & Stocker, R. The role of placental tryptophan catabolism. Frontiers in immunology 5, 230, doi:10.3389/ fimmu.2014.00230 (2014).
40. Blaschitz, A. et al. Vascular endothelial expression of indoleamine 2, 3-dioxygenase 1 forms a positive gradient towards the fetomaternal interface. PLoS One 6, e21774, doi:10.1371/journal.pone.0021774 (2011).
41. Sedlmayr, P. et al. Localization of indoleamine 2, 3-dioxygenase in human female reproductive organs and the placenta. Molecular human reproduction 8, 385-391 (2002).
42. Davis, B. A., Raubertas, R. F., Pearson, S. K. & Bowen, W. H. The effects of benzoate and fluoride on dental caries in intact and desalivated rats. Caries research 35, 331-337, doi:47471 (2001).
43. Aschenbrenner, D. S. J. V. Drug therapy in nursing. Lippincott Williams & Wilkins, 1306 (2009).
44. Koren, O. et al. Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy. Cell 150, 470-480, doi:10.1016/j. cell.2012.07.008 (2012).
45. Yu, Z. & Morrison, M. Improved extraction of PCR-quality community DNA from digesta and fecal samples. BioTechniques 36, 808-812 (2004).
46. Gomez-Arango, L. F. et al. Connections Between the Gut Microbiome and Metabolic Hormones in Early Pregnancy in Overweight and Obese Women. 65, 2214-2223, doi:10.2337/db16-0278 (2016).
47. Caporaso, J. G. et al. QIIME allows analysis of high-throughput community sequencing data. Nature methods 7, 335-336, doi:10.1038/nmeth.f.303 (2010).
48. DeSantis, T. Z. et al. Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Applied and environmental microbiology 72, 5069-5072, doi:10.1128/aem.03006-05 (2006).
49. Paulson, J. N., Stine, O. C., Bravo, H. C. & Pop, M. Differential abundance analysis for microbial marker-gene surveys. Nature methods 10, 1200-1202, doi:10.1038/nmeth.2658 (2013).
50. Knights, D. et al. Bayesian community-wide culture-independent microbial source tracking. Nature methods 8, 761-763, doi:10.1038/nmeth.1650 (2011).
51. Oliveros, J. C. An interactive tool for comparing lists with Venn's diagrams. (2015).
52. Langille, M. G. et al. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nature biotechnology 31, 814-821, doi:10.1038/nbt.2676 (2013).
53. Segata, N. et al. Metagenomic biomarker discovery and explanation. Genome biology 12, R60, doi:10.1186/gb-2011-12-6-r60 (2011).