Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils

Blood

Volumn 130, Issue 3, 2017, Pages 328-339

  Khan, Zakir ^a   Shen, Xiao Z ^b   Bernstein, Ellen A ^a   Giani, Jorge F ^a   Eriguchi, Masahiro ^a   Zhao, Tuantuan V ^a   Gonzalez Villalobos, Romer A ^a,c   Fuchs, Sebastien ^d   Liu, George Y ^a   Bernstein, Kenneth E ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c PFIZER INC   (United States)

^d WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; COMPLEMENTARY DNA; CYTOCHROME C; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOUBLE STRANDED DNA; INTERLEUKIN 1BETA; MYELOPEROXIDASE; PEROXIDASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; AGTR1A PROTEIN, MOUSE; IL1B PROTEIN, MOUSE; NEUTROPHIL CYTOSOL FACTOR 67K; NEUTROPHIL CYTOSOLIC FACTOR 1; PHOSPHOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL COUNT; BACTERIAL LOAD; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; COLONY FORMING UNIT; CYTOKINE PRODUCTION; ENZYME ACTIVITY; EX VIVO STUDY; EXTRACELLULAR TRAP; GRANULOCYTE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; INNATE IMMUNITY; INTRACELLULAR SIGNALING; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATION; PATHOGENESIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; ANIMAL; CELL MEMBRANE; CYTOLOGY; DEFICIENCY; DISEASE RESISTANCE; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; MALE; METABOLISM; MICROBIOLOGY; SIGNAL TRANSDUCTION; STAPHYLOCOCCAL INFECTIONS; TRANSPLANTATION;

ANIMALS; CELL MEMBRANE; DISEASE RESISTANCE; EXTRACELLULAR TRAPS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-1BETA; KLEBSIELLA PNEUMONIAE; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICE, KNOCKOUT; NADPH OXIDASE; NEUTROPHILS; PEPTIDYL-DIPEPTIDASE A; PHOSPHOPROTEINS; PSEUDOMONAS AERUGINOSA; RECEPTOR, ANGIOTENSIN, TYPE 1; SIGNAL TRANSDUCTION; STAPHYLOCOCCAL INFECTIONS; SUPEROXIDES;

EID: 85020499411     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-11-752006     Document Type: Article

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