Angiotensin-converting enzyme is required for normal myelopoiesis

FASEB Journal

Volumn 25, Issue 4, 2011, Pages 1145-1155

  Lin, Chentao ^a   Datta, Vivekanand ^b   Okwan Duodu, Derick ^a,c   Chen, Xu ^a   Fuchs, Sebastien ^a,b   Alsabeh, Randa ^b   Billet, Sandrine ^a   Bernstein, Kenneth E ^a,b   Shen, Xiao Z ^a,d  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b Cedars Sinai Medical Center   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

Myelodifferentiation; Myeloid proliferation; Substance P

Indexed keywords

3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; CCAAT ENHANCER BINDING PROTEIN ALPHA; CD86 ANTIGEN; DIPEPTIDYL CARBOXYPEPTIDASE; GAMMA INTERFERON; GROWTH FACTOR; INTERLEUKIN 12; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LISINOPRIL; LOSARTAN; NEUROKININ 1 RECEPTOR; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL EXPANSION; CELL MATURATION; CELL PROLIFERATION; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOLOGY; MACROPHAGE; MOUSE; MYELOBLAST; MYELOPOIESIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTE; STAPHYLOCOCCUS INFECTION; UPREGULATION;

ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELL LINEAGE; LISINOPRIL; MACROPHAGES; MICE; MICE, KNOCKOUT; MYELOPOIESIS; PEPTIDYL-DIPEPTIDASE A; SUBSTANCE P; UP-REGULATION;

CUCURBITA; MUS; STAPHYLOCOCCUS AUREUS;

EID: 79954586443     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-169433     Document Type: Article

References (42)

1. Park, T. S., and Zambidis, E. T. (2009) A role for the reninangiotensin system in hematopoiesis. Haematologica 94, 745-747
2. Corvol, P., Williams, T. A., and Soubrier, F. (1995) Peptidyl dipeptidase A: angiotensin I-converting enzyme. Methods Enzymol. 248, 283-305
3. Rameshwar, P., Ganea, D., and Gascon, P. (1993) In vitro stimulatory effect of substance P on hematopoiesis. Blood 81, 391-398 (Pubitemid 23027155)
4. Rodgers, K. E., Xiong, S., Steer, R., and diZerega, G. S. (2000) Effect of angiotensin II on hematopoietic progenitor cell proliferation. Stem Cells 18, 287-294 (Pubitemid 30602276)
5. Sugaya, T., Nishimatsu, S., Tanimoto, K., Takimoto, E., Yamagishi, T., Imamura, K., Goto, S., Imaizumi, K., Hisada, Y., Otsuka, A., Uchida, H., Sugiura, M., Fukuta, K., Fukamizu, A., and Murakami, K. (1995) Angiotensin II type 1a receptor-deficient mice with hypotension and hyperreninemia. J. Biol. Chem. 270, 18719-18722
6. Rameshwar, P., and Gascon, P. (1995) Substance P (SP) mediates production of stem cell factor and interleukin-1 in bone marrow stroma: potential autoregulatory role for these cytokines in SP receptor expression and induction. Blood 86, 482-490
7. Strawn, W. B., Richmond, R. S., Ann Tallant, E., Gallagher, P. E., and Ferrario, C. M. (2004) Renin-angiotensin system expression in rat bone marrow haematopoietic and stromal cells. Br. J. Haematol. 126, 120-126 (Pubitemid 38859492)
8. Nowicki, M., Ostalska-Nowicka, D., Kondraciuk, B., and Miskowiak, B. (2007) The significance of substance P in physiological and malignant haematopoiesis. J. Clin. Pathol. 60, 1749-755
9. Re, R. N. (2001) The clinical implication of tissue renin angiotensin systems. Curr. Opin. Cardiol. 16, 317-327 (Pubitemid 33135219)
10. Griffing, G. T., and Melby, J. C. (1982) Enalapril (MK-421) and the white cell count and haematocrit. Lancet 1, 1361
11. Pratt, M. C., Lewis-Barned, N. J., Walker, R. J., Bailey, R. R., Shand, B. I., and Livesey, J. (1992) Effect of angiotensin converting enzyme inhibitors on erythropoietin concentrations in healthy volunteers. Br. J. Clin. Pharmacol. 34, 363-365
12. Cole, J., Ertoy, D., Lin, H., Sutliff, R. L., Ezan, E., Guyene, T. T., Capecchi, M., Corvol, P., and Bernstein, K. E. (2000) Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice. J. Clin. Invest. 106, 1391-1398
13. Kato, H., Ishida, J., Imagawa, S., Saito, T., Suzuki, N., Matsuoka, T., Sugaya, T., Tanimoto, K., Yokoo, T., Ohneda, O., Sugiyama, F., Yagami, K., Fujita, T., Yamamoto, M., Nangaku, M., and Fukamizu, A. (2005) Enhanced erythropoiesis mediated by activation of the renin-angiotensin system via angiotensin II type 1a receptor. FASEB J. 19, 2023-2025 (Pubitemid 41759752)
14. Mrug, M., Stopka, T., Julian, B. A., Prchal, J. F., and Prchal, J. T. (1997) Angiotensin II stimulates proliferation of normal early erythroid progenitors. J. Clin. Invest. 100, 2310-2314 (Pubitemid 27500154)
15. Billet, S., Bardin, S., Verp, S., Baudrie, V., Michaud, A., Conchon, S., Muffat-Joly, M., Escoubet, B., Souil, E., Hamard, G., Bernstein, K. E., Gasc, J. M., Elghozi, J. L., Corvol, P., and Clauser, E. (2007) Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice. J. Clin. Invest. 117, 1914-1925 (Pubitemid 47036325)
16. Zambidis, E. T., Park, T. S., Yu, W., Tam, A., Levine, M., Yuan, X., Pryzhkova, M., and Peault, B. (2008) Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells. Blood 112, 3601-3614
17. Jokubaitis, V. J., Sinka, L., Driessen, R., Whitty, G., Haylock, D. N., Bertoncello, I., Smith, I., Peault, B., Tavian, M., and Simmons, P. J. (2008) Angiotensin-converting enzyme (CD143) marks hematopoietic stem cells in human embryonic, fetal, and adult hematopoietic tissues. Blood 111, 4055-4063
18. Aksu, S., Beyazit, Y., Haznedaroglu, I. C., Canpinar, H., Kekilli, M., Uner, A., Sayinalp, N., Buyukasik, Y., Goker, H., and Ozcebe, O. I. (2006) Over-expression of angiotensin-converting enzyme (CD 143) on leukemic blasts as a clue for the activated local bone marrow RAS in AML. Leuk. Lymphoma 47, 891-896 (Pubitemid 43840646)
19. Rousseau-Plasse, A., Wdzieczak-Bakala, J., Lenfant, M., Ezan, E., Genet, R., Robinson, S., Briscoe, T., Melville, J., and Riches, A. (1998) Lisinopril, an angiotensin I-converting enzyme inhibitor, prevents entry of murine hematopoietic stem cells into the cell cycle after irradiation in vivo. Exp. Hematol. 26, 1074-1079 (Pubitemid 28477775)
20. Charrier, S., Michaud, A., Badaoui, S., Giroux, S., Ezan, E., Sainteny, F., Corvol, P., and Vainchenker, W. (2004) Inhibition of angiotensin I-converting enzyme induces radioprotection by preserving murine hematopoietic short-term reconstituting cells. Blood 104, 978-985 (Pubitemid 39038016)
21. Esther, C. R., Jr., Howard, T. E., Marino, E. M., Goddard, J. M., Capecchi, M. R., and Bernstein, K. E. (1996) Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Lab. Invest. 74, 953-965 (Pubitemid 26152664)
22. Davies, J. Q., and Gordon, S. (2005) 1Isolation and culture of murine macrophages. Methods Mol. Biol. 290, 91-103
23. Scholzen, T. E., and Luger, T. A. (2004) Neutral endopeptidase and angiotensin-converting enzyme-key enzymes terminating the action of neuroendocrine mediators. Exp. Dermatol. 13 (Suppl. 4), 22-26 (Pubitemid 39654437)
24. De Giorgio, R., Tazzari, P. L., Barbara, G., Stanghellini, V., and Corinaldesi, R. (1998) Detection of substance P immunoreactivity in human peripheral leukocytes. J. Neuroimmunol. 82, 175-181 (Pubitemid 28179920)
25. Friedman, A. D. (2007) C/EBPalpha induces PU. 1 and interacts with AP-1 and NF-kappaB to regulate myeloid development. Blood Cells Mol. Dis. 39, 340-343 (Pubitemid 47496146)
26. Iwasaki, H., and Akashi, K. (2007) Myeloid lineage commitment from the hematopoietic stem cell. Immunity 26, 726-740 (Pubitemid 46907674)
27. Zhang, D. E., Zhang, P., Wang, N. D., Hetherington, C. J., Darlington, G. J., and Tenen, D. G. (1997) Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 94, 569-574 (Pubitemid 27053674)
28. Zhang, P., Iwama, A., Datta, M. W., Darlington, G. J., Link, D. C., and Tenen, D. G. (1998) Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis. J. Exp. Med. 188, 1173-1184 (Pubitemid 28443340)
29. Shen, X. Z., Lukacher, A. E., Billet, S., Williams, I. R., and Bernstein, K. E. (2008) Expression of angiotensin-converting enzyme changes major histocompatibility complex class I peptide presentation by modifying C termini of peptide precursors. J. Biol. Chem. 283, 9957-9965
30. Haznedaroglu, I. C., and Ozturk, M. A. (2003) Towards the understanding of the local hematopoietic bone marrow reninangiotensin system. Int. J. Biochem. Cell Biol. 35, 867-880 (Pubitemid 36379328)
31. Tsubakimoto, Y., Yamada, H., Yokoi, H., Kishida, S., Takata, H., Kawahito, H., Matsui, A., Urao, N., Nozawa, Y., Hirai, H., Imanishi, J., Ashihara, E., Maekawa, T., Takahashi, T., Okigaki, M., and Matsubara, H. (2009) Bone marrow angiotensin AT1 receptor regulates differentiation of monocyte lineage progenitors from hematopoietic stem cells. Arterioscler. Thromb. Vasc. Biol. 29, 1529-1536
32. Pascual, D. W., and Bost, K. L. (1990) Substance P production by P388D1 macrophages: a possible autocrine function for this neuropeptide. Immunology 71, 52-56 (Pubitemid 20296071)
33. Greeno, E. W., Mantyh, P., Vercellotti, G. M., and Moldow, C. F. (1993) Functional neurokinin 1 receptors for substance P are expressed by human vascular endothelium. J. Exp. Med. 177, 1269-1276 (Pubitemid 23117118)
34. Garcia, G. E. ANG II receptor antagonists as modulators of macrophages polarization. (2010) Am. J. Physiol. Renal Physiol. 298, F868-F869
35. Alonso, F., Krattinger, N., Mazzolai, L., Simon, A., Waeber, G., Meda, P., and Haefliger, J. A. (2010) An angiotensin II-and NF-κB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension. Cardiovasc. Res. 87, 166-176
36. Nagai, Y., Garrett, K. P., Ohta, S., Bahrun, U., Kouro, T., Akira, S., Takatsu, K., and Kincade, P. W. (2006) Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 24, 801-812 (Pubitemid 43867369)
37. Ueda, Y., Cain, D. W., Kuraoka, M., Kondo, M., and Kelsoe, G. (2009) IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia. J. Immunol 182, 6477-6484
38. Yao, Z., Li, P., Zhang, Q., Schwarz, E. M., Keng, P., Arbini, A., Boyce, B. F., and Xing, L. (2006) Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J. Biol. Chem. 281, 11846-11855 (Pubitemid 43855445)
39. Riviere, G., Michaud, A., Corradi, H. R., Sturrock, E. D., Ravi Acharya, K., Cogez, V., Bohin, J. P., Vieau, D., and Corvol, P. (2007) Characterization of the first angiotensin-converting like enzyme in bacteria: ancestor ACE is already active. Gene 399, 81-90 (Pubitemid 47069803)
40. Bonnet, D., Lemoine, F. M., Khoury, E., Pradelles, P., Najman, A, and Guigon, M. (1992) Reversible inhibitory effects and absence of toxicity of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) in human long-term bone marrow culture. Exp. Hematol. 20, 1165-1169
41. Rodgers, K., Xiong, S., and DiZerega, G. S. (2003) Effect of angiotensin II and angiotensin (1-7) on hematopoietic recovery after intravenous chemotherapy. Cancer Chemother. Pharmacol. 151, 97-106 (Pubitemid 36259469)
42. Bramucci, M., Miano, A., Quassinti, L., Maccari, E., Murri, O., and Amici, D. (1999) Presence and comparison of angiotensin converting enzyme in commercial cell culture sera. Biochem. Mol. Biol. Int. 47, 107-115 (Pubitemid 29112710)