Changes in gene expression of granulocytes during in vivo granulocyte colony-stimulating factor/dexamethasone mobilization for transfusion purposes

Blood

Volumn 113, Issue 23, 2009, Pages 5979-5998

  Drewniak, Agata ^a,b   Van Raam, Bram J ^a,b   Geissler, Judy ^a   Tool, Anton T J ^a   Mook, Olaf R F ^c   Van Den Berg, Timo K ^a   Baas, Frank ^c   Kuijpers, Taco W ^a,b  

^a SANQUIN RESEARCH   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CALPASTATIN; DEXAMETHASONE; GRANULOCYTE COLONY STIMULATING FACTOR; CALPAIN; ENZYME INHIBITOR; MESSENGER RNA;

APOPTOSIS; ARTICLE; CAST GENE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE; GENE EXPRESSION PROFILING; GRANULOCYTE; GRANULOCYTE TRANSFUSION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; NEUTROPHIL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; UNINDEXED SEQUENCE; BLOOD TRANSFUSION; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

APOPTOSIS; BLOOD TRANSFUSION; CALPAIN; DEXAMETHASONE; ENZYME INHIBITORS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTES; HUMANS; MALE; NEUTROPHILS; RNA, MESSENGER;

EID: 67651125048     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-10-182147     Document Type: Article

References (53)

1. Grigg A, Vecchi L, Bardy P, Szer J. G-CSF stimulated donor granulocyte collections for prophylaxis and therapy of neutropenic sepsis. Aust N Z J Med. 1996;26:813-818. (Pubitemid 27072788)
2. Price TH, Bowden RA, Boeckh M, et al. Phase I/II trial of neutrophil transfusions from donors stimulated with G-CSF and dexamethasone for treatment of patients with infections in hematopoietic stem cell transplantation. Blood. 2000;95:3302-3309. (Pubitemid 30428457)
3. Grigull L, Pulver N, Goudeva L, et al. G-CSF mobilised granulocyte transfusions in 32 paediatric patients with neutropenic sepsis. Support Care Cancer. 2006;14:910-916. (Pubitemid 44244054)
4. Liles WC, Huang JE, Llewellyn C, et al. A comparative trial of granulocyte-colony-stimulating factor and dexamethasone, separately and in combination, for the mobilization of neutrophils in the peripheral blood of normal volunteers. Transfusion. 1997;37:182-187. (Pubitemid 27091904)
5. Eyles JL, Roberts AW, Metcalf D, Wicks IP. Granulocyte colony-stimulating factor and neutrophils-forgotten mediators of inflammatory disease. Nat Clin Pract Rheumatol. 2006;2:500-510. (Pubitemid 44340426)
6. Roilides E, Uhlig K, Venzon D, Pizzo PA, Walsh TJ. Prevention of corticosteroid-induced suppression of human polymorphonuclear leukocyte-induced damage of Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon. Infect Immun. 1993;61:4870-4877. (Pubitemid 23320547)
7. Nohmi T, Abe S, Tansho S, Yamaguchi H. Suppression of anti-Candida activity of murine and human neutrophils by glucocorticoids. Microbiol Immunol. 1994;38:977-982.
8. Filep JG, Delalandre A, Payette Y, Foldes-Filep E. Glucocorticoid receptor regulates expression of L-selectin and CD11/CD18 on human neutrophils. Circulation. 1997;96:295-301. (Pubitemid 27298435)
9. Leavey PJ, Sellins KS, Thurman G, et al. In vivo treatment with granulocyte colony-stimulating factor results in divergent effects on neutrophil functions measured in vitro. Blood. 1998;92:4366-4374.
10. Drewniak A, Boelens JJ, Vrielink H, et al. Granulocyte concentrates: prolonged functional capacity during storage in the presence of phenotypic changes. Haematologica. 2008;93: 1058-1067 (Pubitemid 351957023)
11. Colotta F, Re F, Polentarutti N, Sozzani S, Mantovani A. Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood. 1992;80:2012-2020.
12. Adachi S, Kubota M, Lin YW, et al. In vivo administration of granulocyte colony-stimulating factor promotes neutrophil survival in vitro. Eur J Haematol. 1994;53:129-134.
13. Liles WC, Dale DC, Klebanoff SJ. Glucocorticoids inhibit apoptosis of human neutrophils. Blood. 1995;86:3181-3188.
14. Chuang PI, Yee E, Karsan A, Winn RK, Harlan JM. A1 is a constitutive and inducible Bcl-2 homologue in mature human neutrophils. Biochem Biophys Res Commun. 1998;249:361-365. (Pubitemid 28431758)
15. Sivertson KL, Seeds MC, Long DL, Peachman KK, Bass DA. The differential effect of dexamethasone on granulocyte apoptosis involves stabilization of Mcl-1L in neutrophils but not in eosinophils. Cell Immunol. 2007;246:34-45.
16. Maianski NA, Mul FP, van Buul JD, Roos D, Kuijpers TW. Granulocyte colony-stimulating factor inhibits the mitochondria-dependent activation of caspase-3 in neutrophils. Blood. 2002;99:672-679. (Pubitemid 34533107)
17. van Raam BJ, Drewniak A, Groenewold V, van den Berg TK, Kuijpers TW. Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3. Blood. 2008;112:2046-2054.
18. Knepper-Nicolai B, Savill J, Brown SB. Constitutive apoptosis in human neutrophils requires synergy between calpains and the proteasome downstream of caspases. J Biol Chem. 1998;273: 30530-30536. (Pubitemid 28545529)
19. Kobayashi S, Yamashita K, Takeoka T, et al. Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia. J Biol Chem. 2002;277:33968-33977. (Pubitemid 35056213)
20. Altznauer F, Conus S, Cavalli A, Folkers G, Simon HU. Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis. J Biol Chem. 2004;279: 5947-5957. (Pubitemid 38220627)
21. Kuijpers TW, Tool AT, van der Schoot CE, et al. Membrane surface antigen expression on neutrophils: a reappraisal of the use of surface markers for neutrophil activation. Blood. 1991;78:1105-1111.
22. Roos D, de Boer M. Purification and cryopreservation of phagocytes from human blood. Methods Enzymol. 1986;132:225-243. (Pubitemid 17233572)
23. van Stijn A, Rowshani AT, Yong SL, et al. Human cytomegalovirus infection induces a rapid and sustained change in the expression of NK cell receptors on CD8+ T cells. J Immunol. 2008;180: 4550-4560.
24. Barret ER. Gene Expression Omnibus (GEO): Microarray data storage, submission, retrieval, and analysis. Methods Enzymol. 2006;411:352-369.
25. van Mirre E, Breunis WB, Geissler J, et al. Neutrophil responsiveness to IgG, as determined by fixed ratios of mRNA levels for activating and inhibitory FcgammaRII (CD32), is stable over time and unaffected by cytokines. Blood. 2006;108: 584-590. (Pubitemid 44063467)
26. Stroncek DF, Matthews CL, Follmann D, Leitman SF. Kinetics of G-CSF-induced granulocyte mobilization in healthy subjects: effects of route of administration and addition of dexamethasone. Transfusion. 2002;42:597-602.
27. Matmati M, Pouwels W, van Bruggen R, et al. The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes. J Leukoc Biol. 2007;81: 440-448. (Pubitemid 46198395)
28. Buzzeo MP, Yang J, Casella G, Reddy V. Hematopoietic stem cell mobilization with G-CSF induces innate inflammation yet suppresses adaptive immune gene expression as revealed by microarray analysis. Exp Hematol. 2007;35:1456-1465. (Pubitemid 47302592)
29. Bakker AB, Baker E, Sutherland GR, Phillips JH, Lanier LL. Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells. Proc Natl Acad Sci U S A. 1999;96:9792-9796. (Pubitemid 29398811)
30. Arce I, Martinez-Munoz L, Roda-Navarro P, Fernandez-Ruiz E. The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. Eur J Immunol. 2004;34:210-220. (Pubitemid 38111537)
31. Barondes SH, Castronovo V, Cooper DN, et al. Galectins: a family of animal beta-galactoside-binding lectins. Cell. 1994;76:597-598. (Pubitemid 24070645)
32. Rabinovich GA, Rubinstein N, Toscano MA. Role of galectins in inflammatory and immunomodulatory processes. Biochim Biophys Acta. 2002;1572:274-284. (Pubitemid 35246350)
33. Farnworth SL, Henderson NC, MacKinnon AC, et al. Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function. Am J Pathol. 2008;172:395-405.
34. Gupta M, Gupta SK, Balliet AG, et al. Hematopoietic cells from Gadd45a- and Gadd45bdeficient mice are sensitized to genotoxic-stress-induced apoptosis. Oncogene. 2005; 24:7170-7179. (Pubitemid 41679279)
35. Gupta M, Gupta SK, Hoffman B, Liebermann DA. Gadd45a and Gadd45b protect hematopoietic cells from UV-induced apoptosis via distinct signaling pathways, including p38 activation and JNK inhibition. J Biol Chem. 2006;281:17552-17558. (Pubitemid 44035554)
36. Todd B, Moore D, Deivanayagam CC, et al. A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J Mol Biol. 2003;328:131-146. (Pubitemid 36390286)
37. Wolach B, van der Laan LJ, Maianski NA, et al. Growth factors G-CSF and GM-CSF differentially preserve chemotaxis of neutrophils aging in vitro. Exp Hematol. 2007;35:541-550. (Pubitemid 46427962)
38. Schmidt M, Pauels HG, Lugering N, et al. Glucocorticoids induce apoptosis in human monocytes: potential role of IL-1 beta. J Immunol. 1999;163:3484-3490. (Pubitemid 29431853)
39. Meagher LC, Cousin JM, Seckl JR, Haslett C. Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. J Immunol. 1996;156: 4422-4428. (Pubitemid 26165843)
40. Kato T, Takeda Y, Nakada T, Sendo F. Inhibition by dexamethasone of human neutrophil apoptosis in vitro. Nat Immunol. 1995;14:198-208. (Pubitemid 26146447)
41. Melloni E, De Tullio R, Averna M, et al. Properties of calpastatin forms in rat brain. FEBS Lett. 1998; 431:55-58. (Pubitemid 28330851)
42. Wang KK, Posmantur R, Nadimpalli R, et al. Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis. Arch Biochem Biophys. 1998;356:187-196. (Pubitemid 28387723)
43. Blomgren K, Hallin U, Andersson AL, et al. Calpastatin is up-regulated in response to hypoxia and is a suicide substrate to calpain after neonatal cerebral hypoxia-ischemia. J Biol Chem. 1999; 274:14046-14052. (Pubitemid 129518709)
44. Bussolino F, Wang JM, Defilippi P, et al. Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. Nature. 1989;337:471-473. (Pubitemid 19047464)
45. Avalos BR. Molecular analysis of the granulocyte colony-stimulating factor receptor. Blood. 1996; 88:761-777. (Pubitemid 26333294)
46. Schneider A, Kruger C, Steigleder T, et al. The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest. 2005;115: 2083-2098. (Pubitemid 41134150)
47. Hayashi R, Wada H, Ito K, Adcock IM. Effects of glucocorticoids on gene transcription. Eur J Pharmacol. 2004;500:51-62.
48. Lévesque JP, Hendy J, Takamatsu Y, et al. Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment. Exp Hematol. 2002;30:440-449. (Pubitemid 34556735)
49. Hubel K, Rodger E, Gaviria JM, et al. Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte-colony-stimulating factor. Transfusion. 2005;45:1876-1889. (Pubitemid 43971414)
50. Mochizuki K, Kikuta A, Ohto H, et al. Extended storage of granulocyte concentrates mobilized by G-CSF with/without dexamethasone and collected by bag separation method. Transfus Med. 2007;17:296-303. (Pubitemid 47197758)
51. Inomata M, Hayashi M, Nakamura M, Saito Y, Kawashima S. Properties of erythrocyte membrane binding and autolytic activation of calcium-activated neutral protease. J Biol Chem. 1989; 264:18838-18843. (Pubitemid 19277637)
52. Kato M, Nonaka T, Maki M, Kikuchi H, Imajoh-Ohmi S. Caspases cleave the aminoterminal calpain inhibitory unit of calpastatin during apoptosis in human Jurkat T cells. J Biochem. 2000;127:297-305. (Pubitemid 30136913)
53. Squier MK, Sehnert AJ, Sellins KS, et al. Calpain and calpastatin regulate neutrophil apoptosis. J Cell Physiol. 1999;178:311-319.