메뉴 건너뛰기




Volumn 71, Issue 3, 2017, Pages 366-374

The PD-1 expressing immune phenotype of T cell exhaustion is prominent in the ‘immunoreactive’ microenvironment of colorectal carcinoma

Author keywords

anti tumour immunity; colorectal cancer; PD 1; T cell exhaustion; tumour infiltrating lymphocytes

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHLORDANE; GRANZYME B; PROGRAMMED DEATH 1 LIGAND 1; PROTEIN S 100; TRANSCRIPTION FACTOR FOXP3; PDCD1 PROTEIN, HUMAN; PROGRAMMED DEATH 1 RECEPTOR; TUMOR MARKER;

EID: 85020475365     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/his.13231     Document Type: Article
Times cited : (20)

References (30)
  • 1
    • 0032529466 scopus 로고    scopus 로고
    • CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer
    • Naito Y, Saito K, Shiiba K et al. CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res. 1998; 58; 3491–3494.
    • (1998) Cancer Res. , vol.58 , pp. 3491-3494
    • Naito, Y.1    Saito, K.2    Shiiba, K.3
  • 2
    • 5544242524 scopus 로고    scopus 로고
    • Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
    • Guidoboni M, Gafa R, Viel A et al. Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis. Am. J. Pathol. 2001; 159; 297–304.
    • (2001) Am. J. Pathol. , vol.159 , pp. 297-304
    • Guidoboni, M.1    Gafa, R.2    Viel, A.3
  • 3
    • 0035399602 scopus 로고    scopus 로고
    • Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens
    • Linnebacher M, Gebert J, Rudy W et al. Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens. Int. J. Cancer 2001; 93; 6–11.
    • (2001) Int. J. Cancer , vol.93 , pp. 6-11
    • Linnebacher, M.1    Gebert, J.2    Rudy, W.3
  • 4
    • 84922471654 scopus 로고    scopus 로고
    • Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies
    • Philips GK, Atkins M. Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies. Int. Immunol. 2014; 27; 33–46.
    • (2014) Int. Immunol. , vol.27 , pp. 33-46
    • Philips, G.K.1    Atkins, M.2
  • 5
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry JE. T cell exhaustion. Nat. Immunol. 2011; 12; 492–499.
    • (2011) Nat. Immunol. , vol.12 , pp. 492-499
    • Wherry, J.E.1
  • 6
    • 84959865627 scopus 로고    scopus 로고
    • Regulation of PD-L1: a novel role of pro-survival signalling in cancer
    • Chen J, Jiang CC, Jin L, Zhang XD. Regulation of PD-L1: a novel role of pro-survival signalling in cancer. Ann. Oncol. 2016; 27; 409–416.
    • (2016) Ann. Oncol. , vol.27 , pp. 409-416
    • Chen, J.1    Jiang, C.C.2    Jin, L.3    Zhang, X.D.4
  • 7
    • 84907486438 scopus 로고    scopus 로고
    • The programmed death-1 immune-suppressive pathway: barrier to antitumor immunity
    • Ostrand-Rosenberg S, Horn LA, Haile ST. The programmed death-1 immune-suppressive pathway: barrier to antitumor immunity. J. Immunol. 2014; 193; 3835–3841.
    • (2014) J. Immunol. , vol.193 , pp. 3835-3841
    • Ostrand-Rosenberg, S.1    Horn, L.A.2    Haile, S.T.3
  • 8
    • 84978063254 scopus 로고    scopus 로고
    • Characterisation of PD-L1-positive subsets of microsatellite-unstable colorectal cancers
    • Kim JH, Park HE, Cho N-Y, Lee HS, Kang HG. Characterisation of PD-L1-positive subsets of microsatellite-unstable colorectal cancers. Br. J. Cancer 2016; 115; 490–496.
    • (2016) Br. J. Cancer , vol.115 , pp. 490-496
    • Kim, J.H.1    Park, H.E.2    Cho, N.-Y.3    Lee, H.S.4    Kang, H.G.5
  • 9
    • 84969610700 scopus 로고    scopus 로고
    • PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes
    • Rosenbaum MW, Bledsoe JR, Morales-Oyarvide V, Huynh TG, Mino-Kenudson M. PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes. Mod. Pathol. 2016; 29; 1104–1112.
    • (2016) Mod. Pathol. , vol.29 , pp. 1104-1112
    • Rosenbaum, M.W.1    Bledsoe, J.R.2    Morales-Oyarvide, V.3    Huynh, T.G.4    Mino-Kenudson, M.5
  • 10
    • 84974711217 scopus 로고    scopus 로고
    • PD-L1 expression in tumour buds of colorectal carcinoma
    • Prall F, Hühns M. PD-L1 expression in tumour buds of colorectal carcinoma. Histopathology 2016; 69; 158–159.
    • (2016) Histopathology , vol.69 , pp. 158-159
    • Prall, F.1    Hühns, M.2
  • 12
    • 33847787987 scopus 로고    scopus 로고
    • HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression
    • Dierssen JWF, de Miranda NFCC, Ferrone S et al. HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression. BMC Cancer 2007; 7; 33–44.
    • (2007) BMC Cancer , vol.7 , pp. 33-44
    • Dierssen, J.W.F.1    de Miranda, N.F.C.C.2    Ferrone, S.3
  • 13
    • 84900542868 scopus 로고    scopus 로고
    • The intratumoural subsite and relation of CD8+ and FOXP3+ T lymphocytes in colorectal cancer provide important prognostic clues
    • Ling A, Edin S, Wikberg ML, Öberg Å, Palmqvist R. The intratumoural subsite and relation of CD8+ and FOXP3+ T lymphocytes in colorectal cancer provide important prognostic clues. Br. J. Cancer 2014; 110; 2551–2559.
    • (2014) Br. J. Cancer , vol.110 , pp. 2551-2559
    • Ling, A.1    Edin, S.2    Wikberg, M.L.3    Öberg, Å.4    Palmqvist, R.5
  • 14
    • 84938416397 scopus 로고    scopus 로고
    • Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
    • De Smedt L, Lemahieu J, Palmans S et al. Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis. Br. J. Cancer 2015; 113; 500–509.
    • (2015) Br. J. Cancer , vol.113 , pp. 500-509
    • De Smedt, L.1    Lemahieu, J.2    Palmans, S.3
  • 15
    • 33745500432 scopus 로고    scopus 로고
    • CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies
    • Ogino S, Cantor M, Kawasaki T et al. CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies. Gut 2006; 55; 1000–1006.
    • (2006) Gut , vol.55 , pp. 1000-1006
    • Ogino, S.1    Cantor, M.2    Kawasaki, T.3
  • 16
    • 69449105785 scopus 로고    scopus 로고
    • Chromosomally and microsatellite stable colorectal carcinomas without the CpG island methylator phenotype in a molecular classification
    • Ostwald C, Linnebacher M, Weirich V, Prall F. Chromosomally and microsatellite stable colorectal carcinomas without the CpG island methylator phenotype in a molecular classification. Int. J. Oncol. 2009; 35; 321–327.
    • (2009) Int. J. Oncol. , vol.35 , pp. 321-327
    • Ostwald, C.1    Linnebacher, M.2    Weirich, V.3    Prall, F.4
  • 17
    • 84911446514 scopus 로고    scopus 로고
    • Sequential immunohistochemistry: a promising new tool for the pathology laboratory
    • Van den Brand M, Hoevenaars BM, Sigmans JHM et al. Sequential immunohistochemistry: a promising new tool for the pathology laboratory. Histopathology 2014; 65; 651–657.
    • (2014) Histopathology , vol.65 , pp. 651-657
    • Van den Brand, M.1    Hoevenaars, B.M.2    Sigmans, J.H.M.3
  • 18
    • 67649660551 scopus 로고    scopus 로고
    • Redefining chronic viral infection
    • Virgin HW, Wherry EJ, Ahmed R. Redefining chronic viral infection. Cell 2009; 138; 30–50.
    • (2009) Cell , vol.138 , pp. 30-50
    • Virgin, H.W.1    Wherry, E.J.2    Ahmed, R.3
  • 19
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • Barber DL, Wherry EJ, Masopust D et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006; 439; 682–687.
    • (2006) Nature , vol.439 , pp. 682-687
    • Barber, D.L.1    Wherry, E.J.2    Masopust, D.3
  • 20
    • 84964853563 scopus 로고    scopus 로고
    • Targeting PD-1 and TIM-3 pathways to reverse CD8 T cell exhaustion and enhance ex-vivo T cell responses to autologous dendritic/tumor vaccines
    • Liu J, Zhang S, Hu Y et al. Targeting PD-1 and TIM-3 pathways to reverse CD8 T cell exhaustion and enhance ex-vivo T cell responses to autologous dendritic/tumor vaccines. J. Immunother. 2016; 39; 171–180.
    • (2016) J. Immunother. , vol.39 , pp. 171-180
    • Liu, J.1    Zhang, S.2    Hu, Y.3
  • 21
    • 0022891340 scopus 로고
    • Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 1986; 315; 1650–1659.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 22
    • 0022453271 scopus 로고
    • The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases
    • Jass JR, Atkin WS, Cuzick J et al. The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases. Histopathology 1986; 10; 437–459.
    • (1986) Histopathology , vol.10 , pp. 437-459
    • Jass, J.R.1    Atkin, W.S.2    Cuzick, J.3
  • 23
    • 0028176765 scopus 로고
    • From Dukes through Jass: pathological indicators in rectal cancer
    • Harrison JC, Dean PJ, El-Zeky F, Vander Zwaag R. From Dukes through Jass: pathological indicators in rectal cancer. Hum. Pathol. 1994; 25; 498–505.
    • (1994) Hum. Pathol. , vol.25 , pp. 498-505
    • Harrison, J.C.1    Dean, P.J.2    El-Zeky, F.3    Vander Zwaag, R.4
  • 24
    • 3142604756 scopus 로고    scopus 로고
    • Prognostic role of CD8+ tumor-infiltrating lymphocytes in stage III colorectal cancer with and without microsatellite instability
    • Prall F, Dührkop T, Weirich V et al. Prognostic role of CD8+ tumor-infiltrating lymphocytes in stage III colorectal cancer with and without microsatellite instability. Hum. Pathol. 2004; 35; 808–816.
    • (2004) Hum. Pathol. , vol.35 , pp. 808-816
    • Prall, F.1    Dührkop, T.2    Weirich, V.3
  • 25
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J, Costes A, Sanchez-Cabo F et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313; 1960–1964.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 26
    • 84922367332 scopus 로고    scopus 로고
    • The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy
    • Xiao Y, Freeman GJ. The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy. Cancer Discov. 2015; 5; 16–18.
    • (2015) Cancer Discov. , vol.5 , pp. 16-18
    • Xiao, Y.1    Freeman, G.J.2
  • 27
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012; 487; 330–337.
    • (2012) Nature , vol.487 , pp. 330-337
  • 28
    • 85016170378 scopus 로고    scopus 로고
    • Response to PD-1 blockade in microsatellite stable metastatic colorectal cancer harboring a POLE mutation
    • Gong J, Wang C, Lee PP, Chu P, Fakih M. Response to PD-1 blockade in microsatellite stable metastatic colorectal cancer harboring a POLE mutation. J. Natl. Compr. Canc. Netw. 2017; 15; 142–147.
    • (2017) J. Natl. Compr. Canc. Netw. , vol.15 , pp. 142-147
    • Gong, J.1    Wang, C.2    Lee, P.P.3    Chu, P.4    Fakih, M.5
  • 29
    • 84868632631 scopus 로고    scopus 로고
    • Linear quantification of lymphoid infiltration of the tumor margin: a reproducible method, developed with colorectal cancer tissues, for assessing a highly variable prognostic factor
    • Allard MA, Bachet JB, Beauchet A et al. Linear quantification of lymphoid infiltration of the tumor margin: a reproducible method, developed with colorectal cancer tissues, for assessing a highly variable prognostic factor. Diagn. Pathol. 2012; 7; 156–167.
    • (2012) Diagn. Pathol. , vol.7 , pp. 156-167
    • Allard, M.A.1    Bachet, J.B.2    Beauchet, A.3
  • 30
    • 84890280907 scopus 로고    scopus 로고
    • Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours
    • Galon J, Mlecnik B, Bindea G et al. Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours. J. Pathol. 2014; 232; 199–209.
    • (2014) J. Pathol. , vol.232 , pp. 199-209
    • Galon, J.1    Mlecnik, B.2    Bindea, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.