-
1
-
-
84938579430
-
Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: Significance in claudin-low breast cancer cells
-
Alsuliman A, Colak D, Al-Harazi O, Fitwi H, Tulbah A, Al-Tweigeri T, Al-Alwan M, Ghebeh H (2015) Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: significance in claudin-low breast cancer cells. Mol Cancer 14: 149.
-
(2015)
Mol Cancer
, vol.14
, pp. 149
-
-
Alsuliman, A.1
Colak, D.2
Al-Harazi, O.3
Fitwi, H.4
Tulbah, A.5
Al-Tweigeri, T.6
Al-Alwan, M.7
Ghebeh, H.8
-
2
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K, Pitot HC, Hamid O, Bhatia S, Martins R, Eaton K, Chen S, Salay TM, Alaparthy S, Grosso JF, Korman AJ, Parker SM, Agrawal S, Goldberg SM, Pardoll DM, Gupta A, Wigginton JM (2012) Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 366(26): 2455-2465.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
Pitot, H.C.11
Hamid, O.12
Bhatia, S.13
Martins, R.14
Eaton, K.15
Chen, S.16
Salay, T.M.17
Alaparthy, S.18
Grosso, J.F.19
Korman, A.J.20
Parker, S.M.21
Agrawal, S.22
Goldberg, S.M.23
Pardoll, D.M.24
Gupta, A.25
Wigginton, J.M.26
more..
-
3
-
-
84962366938
-
Differential expression of pd-l1 between primary and metastatic sites in clear-cell renal cell carcinoma
-
Callea M, Albiges L, Gupta M, Cheng SC, Genega EM, Fay AP, Song J, Carvo I, Bhatt RS, Atkins MB, Hodi FS, Choueiri TK, McDermott DF, Freeman GJ, Signoretti S (2015) Differential Expression of PD-L1 between Primary and Metastatic Sites in Clear-Cell Renal Cell Carcinoma. Cancer Immunol Res 3(10): 1158-1164.
-
(2015)
Cancer Immunol Res
, vol.3
, Issue.10
, pp. 1158-1164
-
-
Callea, M.1
Albiges, L.2
Gupta, M.3
Cheng, S.C.4
Genega, E.M.5
Fay, A.P.6
Song, J.7
Carvo, I.8
Bhatt, R.S.9
Atkins, M.B.10
Hodi, F.S.11
Choueiri, T.K.12
McDermott, D.F.13
Freeman, G.J.14
Signoretti, S.15
-
4
-
-
84959865627
-
Regulation of PD-L1: A novel role of pro-survival signalling in cancer
-
Chen J, Jiang CC, Jin L, Zhang XD (2016) Regulation of PD-L1: a novel role of pro-survival signalling in cancer. Ann Oncol 27(3): 409-416.
-
(2016)
Ann Oncol
, vol.27
, Issue.3
, pp. 409-416
-
-
Chen, J.1
Jiang, C.C.2
Jin, L.3
Zhang, X.D.4
-
5
-
-
84923251407
-
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
-
Chen L, Gibbons DL, Goswami S, Cortez MA, Ahn YH, Byers LA, Zhang X, Yi X, Dwyer D, Lin W, Diao L, Wang J, Roybal JD, Patel M, Ungewiss C, Peng D, Antonia S, Mediavilla-Varela M, Robertson G, Jones S, Suraokar M, Welsh JW, Erez B, Wistuba, Chen L, Peng D, Wang S, Ullrich SE, Heymach JV, Kurie JM, Qin FX (2014) Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression. Nat Commun 5: 5241.
-
(2014)
Nat Commun
, vol.5
, pp. 5241
-
-
Chen, L.1
Gibbons, D.L.2
Goswami, S.3
Cortez, M.A.4
Ahn, Y.H.5
Byers, L.A.6
Zhang, X.7
Yi, X.8
Dwyer, D.9
Lin, W.10
Diao, L.11
Wang, J.12
Roybal, J.D.13
Patel, M.14
Ungewiss, C.15
Peng, D.16
Antonia, S.17
Mediavilla-Varela, M.18
Robertson, G.19
Jones, S.20
Suraokar, M.21
Welsh, J.W.22
Erez, B.23
Wistuba24
Chen, L.25
Peng, D.26
Wang, S.27
Ullrich, S.E.28
Heymach, J.V.29
Kurie, J.M.30
Qin, F.X.31
more..
-
6
-
-
84963612049
-
Combining epigenetic and immunotherapy to combat cancer
-
Chiappinelli KB, Zahnow CA, Ahuja N, Baylin SB (2016) Combining epigenetic and immunotherapy to combat cancer. Cancer Res 76(7): 1683-1689.
-
(2016)
Cancer Res
, vol.76
, Issue.7
, pp. 1683-1689
-
-
Chiappinelli, K.B.1
Zahnow, C.A.2
Ahuja, N.3
Baylin, S.B.4
-
7
-
-
84951856362
-
PD-L1 (B7-H1) expression and the immune tumor microenvironment in primary and metastatic breast carcinomas
-
Cimino-Mathews A, Thompson E, Taube JM, Ye X, Lu Y, Meeker A, Xu H, Sharma R, Lecksell K, Cornish TC, Cuka N, Argani P, Emens LA (2016) PD-L1 (B7-H1) expression and the immune tumor microenvironment in primary and metastatic breast carcinomas. Hum Pathol 47(1): 52-63.
-
(2016)
Hum Pathol
, vol.47
, Issue.1
, pp. 52-63
-
-
Cimino-Mathews, A.1
Thompson, E.2
Taube, J.M.3
Ye, X.4
Lu, Y.5
Meeker, A.6
Xu, H.7
Sharma, R.8
Lecksell, K.9
Cornish, T.C.10
Cuka, N.11
Argani, P.12
Emens, L.A.13
-
8
-
-
84964398060
-
Microsatellite instability as a biomarker for PD-1 blockade
-
Dudley JC, Lin MT, Le DT, Eshleman JR (2016) Microsatellite instability as a biomarker for PD-1 blockade. Clin Cancer Res 22(4): 813-820.
-
(2016)
Clin Cancer Res
, vol.22
, Issue.4
, pp. 813-820
-
-
Dudley, J.C.1
Lin, M.T.2
Le, D.T.3
Eshleman, J.R.4
-
9
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, LeabmanM, Xiao Y, Mokatrin A, Koeppen H, Hegde PS, Mellman I, Chen DS, Hodi FS (2014) Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 515(7528): 563-567.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
Fine, G.D.4
Hamid, O.5
Gordon, M.S.6
Sosman, J.A.7
McDermott, D.F.8
Powderly, J.D.9
Gettinger, S.N.10
Kohrt, H.E.11
Horn, L.12
Lawrence, D.P.13
Rost, S.14
Leabman, M.15
Xiao, Y.16
Mokatrin, A.17
Koeppen, H.18
Hegde, P.S.19
Mellman, I.20
Chen, D.S.21
Hodi, F.S.22
more..
-
10
-
-
84928760665
-
Anti-programmed cell death protein-1/ ligand-1 therapy in different cancers
-
Homet Moreno B, Ribas A (2015) Anti-programmed cell death protein-1/ ligand-1 therapy in different cancers. Br J Cancer 112(9): 1421-1427.
-
(2015)
Br J Cancer
, vol.112
, Issue.9
, pp. 1421-1427
-
-
Homet Moreno, B.1
Ribas, A.2
-
11
-
-
84942285381
-
Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1. 1
-
Howitt BE, Shukla SA, Sholl LM, Ritterhouse LL, Watkins JC, Rodig S, Stover E, Strickland KC, D'Andrea AD, Wu CJ, Matulonis UA, Konstantinopoulos PA (2015) Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1. 1 JAMA Oncol 1(9): 1319-1323.
-
(2015)
JAMA Oncol
, vol.1
, Issue.9
, pp. 1319-1323
-
-
Howitt, B.E.1
Shukla, S.A.2
Sholl, L.M.3
Ritterhouse, L.L.4
Watkins, J.C.5
Rodig, S.6
Stover, E.7
Strickland, K.C.8
D'Andrea, A.D.9
Wu, C.J.10
Matulonis, U.A.11
Konstantinopoulos, P.A.12
-
12
-
-
0029954795
-
Assessment of invasive growth pattern and lymphocytic infiltration in colorectal cancer
-
Jass JR, Ajioka Y, Allen JP, Chan YF, Cohen RJ, Nixon JM, Radojkovic M, Restall AP, Stables SR, Zwi LJ (1996) Assessment of invasive growth pattern and lymphocytic infiltration in colorectal cancer. Histopathology 28(6): 543-548.
-
(1996)
Histopathology
, vol.28
, Issue.6
, pp. 543-548
-
-
Jass, J.R.1
Ajioka, Y.2
Allen, J.P.3
Chan, Y.F.4
Cohen, R.J.5
Nixon, J.M.6
Radojkovic, M.7
Restall, A.P.8
Stables, S.R.9
Zwi, L.J.10
-
13
-
-
84934298862
-
Pathologic factors associated with prognosis after adjuvant chemotherapy in stage II/III microsatellite-unstable colorectal cancers
-
Kim JH, Bae JM, Oh HJ, Lee HS, Kang GH (2015a) Pathologic factors associated with prognosis after adjuvant chemotherapy in stage II/III microsatellite-unstable colorectal cancers. J Pathol Transl Med 49(2): 118-128.
-
(2015)
J Pathol Transl Med
, vol.49
, Issue.2
, pp. 118-128
-
-
Kim, J.H.1
Bae, J.M.2
Oh, H.J.3
Lee, H.S.4
Kang, G.H.5
-
14
-
-
84971671412
-
Clinicopathologic, molecular, and prognostic implications of the loss of EPCAM expression in colorectal carcinoma
-
Kim JH, Bae JM, Song YS, Cho NY, Lee HS, Kang GH (2015b) Clinicopathologic, molecular, and prognostic implications of the loss of EPCAM expression in colorectal carcinoma. Oncotarget 7: 13372-13387.
-
(2015)
Oncotarget
, vol.7
, pp. 13372-13387
-
-
Kim, J.H.1
Bae, J.M.2
Song, Y.S.3
Cho, N.Y.4
Lee, H.S.5
Kang, G.H.6
-
15
-
-
84919389569
-
Comparative validation of assessment criteria for Crohn-like lymphoid reaction in colorectal carcinoma
-
Kim JH, Kim KJ, Bae JM, Rhee YY, Cho NY, Lee HS, Kang GH (2015c) Comparative validation of assessment criteria for Crohn-like lymphoid reaction in colorectal carcinoma. J Clin Pathol 68(1): 22-28.
-
(2015)
J Clin Pathol
, vol.68
, Issue.1
, pp. 22-28
-
-
Kim, J.H.1
Kim, K.J.2
Bae, J.M.3
Rhee, Y.Y.4
Cho, N.Y.5
Lee, H.S.6
Kang, G.H.7
-
16
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Duffy SM, Goldberg RM, de la Chapelle A, Koshiji M, Bhaijee F, Huebner T, Hruban RH, Wood LD, Cuka N, Pardoll DM, Papadopoulos N, Kinzler KW, Zhou S, Cornish TC, Taube JM, Anders RA, Eshleman JR, Vogelstein B, Diaz Jr. LA (2015) PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med 372(26): 2509-2520.
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
Bartlett, B.R.4
Kemberling, H.5
Eyring, A.D.6
Skora, A.D.7
Luber, B.S.8
Azad, N.S.9
Laheru, D.10
Biedrzycki, B.11
Donehower, R.C.12
Zaheer, A.13
Fisher, G.A.14
Crocenzi, T.S.15
Lee, J.J.16
Duffy, S.M.17
Goldberg, R.M.18
De La Chapelle, A.19
Koshiji, M.20
Bhaijee, F.21
Huebner, T.22
Hruban, R.H.23
Wood, L.D.24
Cuka, N.25
Pardoll, D.M.26
Papadopoulos, N.27
Kinzler, K.W.28
Zhou, S.29
Cornish, T.C.30
Taube, J.M.31
Anders, R.A.32
Eshleman, J.R.33
Vogelstein, B.34
Diaz, L.A.35
more..
-
17
-
-
84922369377
-
The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints
-
Llosa NJ, Cruise M, Tam A, Wicks EC, Hechenbleikner EM, Taube JM, Blosser RL, Fan H, Wang H, Luber BS, Zhang M, Papadopoulos N, Kinzler KW, Vogelstein B, Sears CL, Anders RA, Pardoll DM, Housseau F (2015) The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discov 5(1): 43-51.
-
(2015)
Cancer Discov
, vol.5
, Issue.1
, pp. 43-51
-
-
Llosa, N.J.1
Cruise, M.2
Tam, A.3
Wicks, E.C.4
Hechenbleikner, E.M.5
Taube, J.M.6
Blosser, R.L.7
Fan, H.8
Wang, H.9
Luber, B.S.10
Zhang, M.11
Papadopoulos, N.12
Kinzler, K.W.13
Vogelstein, B.14
Sears, C.L.15
Anders, R.A.16
Pardoll, D.M.17
Housseau, F.18
-
18
-
-
84958836241
-
PD-1 and PD-L1 blockade in gastrointestinal malignancies
-
Lote H, Cafferkey C, Chau I (2015) PD-1 and PD-L1 blockade in gastrointestinal malignancies. Cancer Treat Rev 41(10): 893-903.
-
(2015)
Cancer Treat Rev
, vol.41
, Issue.10
, pp. 893-903
-
-
Lote, H.1
Cafferkey, C.2
Chau, I.3
-
19
-
-
84896488996
-
Tumour-infiltrating inflammation and prognosis in colorectal cancer: Systematic review and meta-analysis
-
Mei Z, Liu Y, Liu C, Cui A, Liang Z, Wang G, Peng H, Cui L, Li C (2014) Tumour-infiltrating inflammation and prognosis in colorectal cancer: systematic review and meta-analysis. Br J Cancer 110(6): 1595-1605.
-
(2014)
Br J Cancer
, vol.110
, Issue.6
, pp. 1595-1605
-
-
Mei, Z.1
Liu, Y.2
Liu, C.3
Cui, A.4
Liang, Z.5
Wang, G.6
Peng, H.7
Cui, L.8
Li, C.9
-
20
-
-
84960413790
-
Programmed death-ligand 1 expression in muscle-invasive bladder cancer cystectomy specimens and lymph node metastasis: A reliable treatment selection biomarker
-
Mukherji D, Jabbour MN, Saroufim M, Temraz S, Nasr R, Charafeddine M, Assi R, Shamseddine A, Tawil AN (2016) Programmed death-ligand 1 expression in muscle-invasive bladder cancer cystectomy specimens and lymph node metastasis: a reliable treatment selection biomarker? Clin Genitourin Cancer 14(2): 183-187.
-
(2016)
Clin Genitourin Cancer
, vol.14
, Issue.2
, pp. 183-187
-
-
Mukherji, D.1
Jabbour, M.N.2
Saroufim, M.3
Temraz, S.4
Nasr, R.5
Charafeddine, M.6
Assi, R.7
Shamseddine, A.8
Tawil, A.N.9
-
21
-
-
84974711217
-
PD-L1 expression in tumour buds of colorectal carcinoma
-
Prall F, Huhns M (2015) PD-L1 expression in tumour buds of colorectal carcinoma. Histopathology 69: 158-160.
-
(2015)
Histopathology
, vol.69
, pp. 158-160
-
-
Prall, F.1
Huhns, M.2
-
22
-
-
84904024273
-
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
-
Taube JM, Klein A, Brahmer JR, Xu H, Pan X, Kim JH, Chen L, Pardoll DM, Topalian SL, Anders RA (2014) Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res 20(19): 5064-5074.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.19
, pp. 5064-5074
-
-
Taube, J.M.1
Klein, A.2
Brahmer, J.R.3
Xu, H.4
Pan, X.5
Kim, J.H.6
Chen, L.7
Pardoll, D.M.8
Topalian, S.L.9
Anders, R.A.10
-
23
-
-
84941797037
-
Classifying cancers based on T-cell infiltration and PD-L1
-
Teng MW, Ngiow SF, Ribas A, Smyth MJ (2015) Classifying cancers based on T-cell infiltration and PD-L1. Cancer Res 75(11): 2139-2145.
-
(2015)
Cancer Res
, vol.75
, Issue.11
, pp. 2139-2145
-
-
Teng, M.W.1
Ngiow, S.F.2
Ribas, A.3
Smyth, M.J.4
-
24
-
-
84928062583
-
Immune checkpoint blockade: A common denominator approach to cancer therapy
-
Topalian SL, Drake CG, Pardoll DM (2015) Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 27(4): 450-461.
-
(2015)
Cancer Cell
, vol.27
, Issue.4
, pp. 450-461
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
25
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M (2012) Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 366(26): 2443-2454.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
Leming, P.D.11
Spigel, D.R.12
Antonia, S.J.13
Horn, L.14
Drake, C.G.15
Pardoll, D.M.16
Chen, L.17
Sharfman, W.H.18
Anders, R.A.19
Taube, J.M.20
McMiller, T.L.21
Xu, H.22
Korman, A.J.23
Jure-Kunkel, M.24
Agrawal, S.25
McDonald, D.26
Kollia, G.D.27
Gupta, A.28
Wigginton, J.M.29
Sznol, M.30
more..
-
26
-
-
84938529978
-
PD-L1 induces epithelial-to-mesenchymal transition via activating SREBP-1c in renal cell carcinoma
-
Wang Y, Wang H, Zhao Q, Xia Y, Hu X, Guo J (2015) PD-L1 induces epithelial-to-mesenchymal transition via activating SREBP-1c in renal cell carcinoma. Med Oncol 32(8): 212.
-
(2015)
Med Oncol
, vol.32
, Issue.8
, pp. 212
-
-
Wang, Y.1
Wang, H.2
Zhao, Q.3
Xia, Y.4
Hu, X.5
Guo, J.6
-
27
-
-
84922367332
-
The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy
-
Xiao Y, Freeman GJ (2015) The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy. Cancer Discov 5(1): 16-18.
-
(2015)
Cancer Discov
, vol.5
, Issue.1
, pp. 16-18
-
-
Xiao, Y.1
Freeman, G.J.2
-
28
-
-
85012982978
-
Clinical significance of programmed death ligand-1 (PD-L1) in colorectal serrated adenocarcinoma
-
Zhu H, Qin H, Huang Z, Li S, Zhu X, He J, Yang J, Yu X, Yi X (2015) Clinical significance of programmed death ligand-1 (PD-L1) in colorectal serrated adenocarcinoma. Int J Clin Exp Pathol 8(8): 9351-9359.
-
(2015)
Int J Clin Exp Pathol
, vol.8
, Issue.8
, pp. 9351-9359
-
-
Zhu, H.1
Qin, H.2
Huang, Z.3
Li, S.4
Zhu, X.5
He, J.6
Yang, J.7
Yu, X.8
Yi, X.9
|