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Volumn 8, Issue , 2017, Pages

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

(36)  Bradley, Todd a   Pollara, Justin a   Santra, Sampa b   Vandergrift, Nathan a   Pittala, Srivamshi c   Bailey Kellogg, Chris c   Shen, Xiaoying a   Parks, Robert a   Goodman, Derrick a   Eaton, Amanda a   Balachandran, Harikrishnan b   MacH, Linh V b   Saunders, Kevin O a   Weiner, Joshua A c   Scearce, Richard a   Sutherland, Laura L a   Phogat, Sanjay d   Tartaglia, Jim d   Reed, Steven G e   Hu, Shiu Lok f   more..


Author keywords

[No Author keywords available]

Indexed keywords

DRUG ANTIBODY; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; COMPLEMENT; EPITOPE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; PROTEIN BINDING; RECOMBINANT PROTEIN;

EID: 85020430149     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms15711     Document Type: Article
Times cited : (110)

References (66)
  • 1
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with alvac and aidsvax to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm, S. et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361, 2209-2220 (2009).
    • (2009) N. Engl. J. Med , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1
  • 2
    • 84862764447 scopus 로고    scopus 로고
    • Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen alvac-HIV (vcp1521) and aidsvax b/e: A post-hoc analysis of the Thai phase 3 efficacy trial rv 144
    • Robb, M. L. et al. Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: a post-hoc analysis of the Thai phase 3 efficacy trial RV 144. Lancet 12, 531-537 (2012).
    • (2012) Lancet , vol.12 , pp. 531-537
    • Robb, M.L.1
  • 3
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn, N. M. et al. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J. Infect. Dis. 191, 654-665 (2005).
    • (2005) J. Infect. Dis , vol.191 , pp. 654-665
    • Flynn, N.M.1
  • 4
    • 33845433434 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    • Pitisuttithum, P. et al. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J. Infect. Dis. 194, 1661-1671 (2006).
    • (2006) J. Infect. Dis , vol.194 , pp. 1661-1671
    • Pitisuttithum, P.1
  • 5
    • 84929896699 scopus 로고    scopus 로고
    • Antibody responses to envelope glycoproteins in HIV-1 infection
    • Burton, D. R. & Mascola, J. R. Antibody responses to envelope glycoproteins in HIV-1 infection. Nat. Immunol. 16, 571-576 (2015).
    • (2015) Nat. Immunol , vol.16 , pp. 571-576
    • Burton, D.R.1    Mascola, J.R.2
  • 6
    • 84903610913 scopus 로고    scopus 로고
    • Progress in HIV-1 vaccine development
    • quiz 11
    • Haynes, B. F. et al. Progress in HIV-1 vaccine development. J. Allergy Clin. Immunol. 134, 3-10 quiz 11 (2014).
    • (2014) J. Allergy Clin. Immunol , vol.134 , pp. 3-10
    • Haynes, B.F.1
  • 7
    • 84859393693 scopus 로고    scopus 로고
    • Immune-correlates analysis of an HIV-1 vaccine efficacy trial
    • Haynes, B. F. et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N. Engl. J. Med. 366, 1275-1286 (2012).
    • (2012) N. Engl. J. Med , vol.366 , pp. 1275-1286
    • Haynes, B.F.1
  • 8
    • 84863932778 scopus 로고    scopus 로고
    • Magnitude and breadth of the neutralizing antibody response in the rv144 and vax003 HIV-1 vaccine efficacy trials
    • Montefiori, D. C. et al. Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials. J. Infect. Dis. 206, 431-441 (2012).
    • (2012) J. Infect. Dis , vol.206 , pp. 431-441
    • Montefiori, D.C.1
  • 9
    • 84899087118 scopus 로고    scopus 로고
    • Vaccine-induced env v1-v2 igg3 correlates with lower HIV-1 infection risk and declines soon after vaccination
    • Yates, N. L. et al. Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination. Sci. Transl. Med. 6, 228ra239 (2014).
    • (2014) Sci. Transl. Med , vol.6 , pp. 228ra239
    • Yates, N.L.1
  • 10
    • 84895174919 scopus 로고    scopus 로고
    • Vaccine-induced igg antibodies to v1v2 regions of multiple HIV-1 subtypes correlate with decreased risk of HIV-1 infection
    • Zolla-Pazner, S. et al. Vaccine-induced IgG antibodies to V1V2 regions of multiple HIV-1 subtypes correlate with decreased risk of HIV-1 infection. PLoS ONE 9, e87572 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e87572
    • Zolla-Pazner, S.1
  • 11
    • 84867653590 scopus 로고    scopus 로고
    • Increased HIV-1 vaccine efficacy against viruses with genetic signatures in env v2
    • Rolland, M. et al. Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2. Nature 490, 417-420 (2012).
    • (2012) Nature , vol.490 , pp. 417-420
    • Rolland, M.1
  • 12
    • 84880357204 scopus 로고    scopus 로고
    • Molecular evolution of the HIV-1 Thai epidemic between the time of rv144 immunogen selection to the execution of the vaccine efficacy trial
    • Kijak, G. H. et al. Molecular evolution of the HIV-1 Thai epidemic between the time of RV144 immunogen selection to the execution of the vaccine efficacy trial. J. Virol. 87, 7265-7281 (2013).
    • (2013) J. Virol , vol.87 , pp. 7265-7281
    • Kijak, G.H.1
  • 13
    • 9544220664 scopus 로고    scopus 로고
    • The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (a/e) recombinant of african origin
    • Gao, F. et al. The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (A/E) recombinant of African origin. J. Virol. 70, 7013-7029 (1996).
    • (1996) J. Virol , vol.70 , pp. 7013-7029
    • Gao, F.1
  • 14
    • 33748650568 scopus 로고    scopus 로고
    • Molecularly cloned sHIV-1157ipd3n4: A highly replicationcompetent, mucosally transmissible r5 simian-human immunodeficiency virus encoding HIV clade c env
    • Song, R. J. et al. Molecularly cloned SHIV-1157ipd3N4: a highly replicationcompetent, mucosally transmissible R5 simian-human immunodeficiency virus encoding HIV clade C Env. J. Virol. 80, 8729-8738 (2006).
    • (2006) J. Virol , vol.80 , pp. 8729-8738
    • Song, R.J.1
  • 15
    • 33846111016 scopus 로고    scopus 로고
    • Polyvalent vaccines for optimal coverage of potential t-cell epitopes in global HIV-1 variants
    • Fischer, W. et al. Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nat. Med. 13, 100-106 (2007).
    • (2007) Nat. Med , vol.13 , pp. 100-106
    • Fischer, W.1
  • 16
    • 84894593765 scopus 로고    scopus 로고
    • Toll-like receptor 7/8 (tlr7/8) and tlr9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques
    • Moody, M. A. et al. Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques. J. Virol. 88, 3329-3339 (2014).
    • (2014) J. Virol , vol.88 , pp. 3329-3339
    • Moody, M.A.1
  • 17
    • 84872809067 scopus 로고    scopus 로고
    • Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2
    • Liao, H. X. et al. Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. Immunity 38, 176-186 (2013).
    • (2013) Immunity , vol.38 , pp. 176-186
    • Liao, H.X.1
  • 18
    • 84860723906 scopus 로고    scopus 로고
    • Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: Implications for vaccine design
    • Bonsignori, M. et al. Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design. J. Virol. 86, 4688-4692 (2012).
    • (2012) J. Virol , vol.86 , pp. 4688-4692
    • Bonsignori, M.1
  • 19
    • 79960342938 scopus 로고    scopus 로고
    • An HIV-1 gp120 envelope human monoclonal antibody that recognizes a c1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (adcc) activity and defines a common adcc epitope in human HIV-1 serum
    • Ferrari, G. et al. An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum. J. Virol. 85, 7029-7036 (2011).
    • (2011) J. Virol , vol.85 , pp. 7029-7036
    • Ferrari, G.1
  • 20
    • 84880816240 scopus 로고    scopus 로고
    • Epitope mapping of conformational v2-specific anti-HIV human monoclonal antibodies reveals an immunodominant site in v2
    • Mayr, L. M., Cohen, S., Spurrier, B., Kong, X. P. & Zolla-Pazner, S. Epitope mapping of conformational V2-specific anti-HIV human monoclonal antibodies reveals an immunodominant site in V2. PLoS ONE 8, e70859 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e70859
    • Mayr, L.M.1    Cohen, S.2    Spurrier, B.3    Kong, X.P.4    Zolla-Pazner, S.5
  • 21
    • 39449098115 scopus 로고    scopus 로고
    • HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral t cells
    • Arthos, J. et al. HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. Nat. Immunol. 9, 301-309 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 301-309
    • Arthos, J.1
  • 22
    • 84873033705 scopus 로고    scopus 로고
    • Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus siv(mac251) acquisition in an immunization regimen that mimics the rv-144 Thai trial
    • Pegu, P. et al. Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial. J. Virol. 87, 1708-1719 (2013).
    • (2013) J. Virol , vol.87 , pp. 1708-1719
    • Pegu, P.1
  • 23
    • 84874670092 scopus 로고    scopus 로고
    • Protection afforded by an HIV vaccine candidate in macaques depends on the dose of sivmac251 at challenge exposure
    • Vaccari, M. et al. Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure. J. Virol. 87, 3538-3548 (2013).
    • (2013) J. Virol , vol.87 , pp. 3538-3548
    • Vaccari, M.1
  • 24
    • 84886778874 scopus 로고    scopus 로고
    • Protective efficacy of a global HIV-1 mosaic vaccine against heterologous sHIV challenges in rhesus monkeys
    • Barouch, D. H. et al. Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys. Cell 155, 531-539 (2013).
    • (2013) Cell , vol.155 , pp. 531-539
    • Barouch, D.H.1
  • 25
    • 84856482137 scopus 로고    scopus 로고
    • Vaccine protection against acquisition of neutralizationresistant siv challenges in rhesus monkeys
    • Barouch, D. H. et al. Vaccine protection against acquisition of neutralizationresistant SIV challenges in rhesus monkeys. Nature 482, 89-93 (2012).
    • (2012) Nature , vol.482 , pp. 89-93
    • Barouch, D.H.1
  • 26
    • 84937950533 scopus 로고    scopus 로고
    • Protective efficacy of adenovirus/protein vaccines against siv challenges in rhesus monkeys
    • Barouch, D. H. et al. Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys. Science 349, 320-324 (2015).
    • (2015) Science , vol.349 , pp. 320-324
    • Barouch, D.H.1
  • 27
    • 84904113226 scopus 로고    scopus 로고
    • HIV-1 vaccine-induced c1 and v2 env-specific antibodies synergize for increased antiviral activities
    • Pollara, J. et al. HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. J. Virol. 88, 7715-7726 (2014).
    • (2014) J. Virol , vol.88 , pp. 7715-7726
    • Pollara, J.1
  • 28
    • 0032540418 scopus 로고    scopus 로고
    • Gastrointestinal tract as a major site of cd4+ t cell depletion and viral replication in siv infection
    • Veazey, R. S. et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 280, 427-431 (1998).
    • (1998) Science , vol.280 , pp. 427-431
    • Veazey, R.S.1
  • 29
    • 84991712477 scopus 로고    scopus 로고
    • Sustained virologic control in siv+ macaques after antiretroviral and alpha4beta7 antibody therapy
    • Byrareddy, S. N. et al. Sustained virologic control in SIV+ macaques after antiretroviral and alpha4beta7 antibody therapy. Science 354, 197-202 (2016).
    • (2016) Science , vol.354 , pp. 197-202
    • Byrareddy, S.N.1
  • 30
    • 84939947397 scopus 로고    scopus 로고
    • Targeting alpha4beta7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-Associated lymphoid tissue from infection
    • Byrareddy, S. N. et al. Targeting alpha4beta7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-Associated lymphoid tissue from infection. Nat. Med. 20, 1397-1400 (2014).
    • (2014) Nat. Med , vol.20 , pp. 1397-1400
    • Byrareddy, S.N.1
  • 31
    • 77950806408 scopus 로고    scopus 로고
    • New algorithms and methods to estimate maximumlikelihood phylogenies: Assessing the performance of phyml 3.0
    • Guindon, S. et al. New algorithms and methods to estimate maximumlikelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol. 59, 307-321 (2010).
    • (2010) Syst Biol , vol.59 , pp. 307-321
    • Guindon, S.1
  • 32
    • 70349778470 scopus 로고    scopus 로고
    • Modeling sequence evolution in acute HIV-1 infection
    • Lee, H. Y. et al. Modeling sequence evolution in acute HIV-1 infection. J. Theor. Biol. 261, 341-360 (2009).
    • (2009) J. Theor. Biol , vol.261 , pp. 341-360
    • Lee, H.Y.1
  • 33
    • 83455254775 scopus 로고    scopus 로고
    • Structure of HIV-1 gp120 v1/v2 domain with broadly neutralizing antibody pg9
    • McLellan, J. S. et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature 480, 336-343 (2011).
    • (2011) Nature , vol.480 , pp. 336-343
    • McLellan, J.S.1
  • 34
    • 47049113161 scopus 로고    scopus 로고
    • Web-based design and evaluation of t-cell vaccine candidates
    • Thurmond, J. et al. Web-based design and evaluation of T-cell vaccine candidates. Bioinformatics 24, 1639-1640 (2008).
    • (2008) Bioinformatics , vol.24 , pp. 1639-1640
    • Thurmond, J.1
  • 35
    • 84875771414 scopus 로고    scopus 로고
    • Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1
    • Liao, H. X. et al. Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1. J. Virol. 87, 4185-4201 (2013).
    • (2013) J. Virol , vol.87 , pp. 4185-4201
    • Liao, H.X.1
  • 36
    • 33746689169 scopus 로고    scopus 로고
    • A group m consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype b and c HIV-1 primary viruses
    • Liao, H. X. et al. A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. Virology 353, 268-282 (2006).
    • (2006) Virology , vol.353 , pp. 268-282
    • Liao, H.X.1
  • 37
    • 84940771125 scopus 로고    scopus 로고
    • Human non-neutralizing HIV-1 envelope monoclonal antibodies limit the number of founder viruses during sHIV mucosal infection in rhesus macaques
    • Santra, S. et al. Human non-neutralizing HIV-1 envelope monoclonal antibodies limit the number of founder viruses during SHIV mucosal infection in rhesus macaques. PLoS Pathogens 11, e1005042 (2015).
    • (2015) PLoS Pathogens , vol.11 , pp. e1005042
    • Santra, S.1
  • 38
    • 80052938385 scopus 로고    scopus 로고
    • Analysis of a clonal lineage of HIV-1 envelope v2/v3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
    • Bonsignori, M. et al. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. J. Virol. 85, 9998-10009 (2011).
    • (2011) J. Virol , vol.85 , pp. 9998-10009
    • Bonsignori, M.1
  • 39
    • 84876797103 scopus 로고    scopus 로고
    • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
    • Liao, H. X. et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature 496, 469-476 (2013).
    • (2013) Nature , vol.496 , pp. 469-476
    • Liao, H.X.1
  • 40
    • 84938125125 scopus 로고    scopus 로고
    • Vaccine-induced linear epitope-specific antibodies to simian immunodeficiency virus sivmac239 envelope are distinct from those induced to the human immunodeficiency virus type 1 envelope in nonhuman primates
    • Shen, X. et al. Vaccine-induced linear epitope-specific antibodies to simian immunodeficiency virus SIVmac239 envelope are distinct from those induced to the human immunodeficiency virus type 1 envelope in nonhuman primates. J. Virol. 89, 8643-8650 (2015).
    • (2015) J. Virol , vol.89 , pp. 8643-8650
    • Shen, X.1
  • 41
    • 80055104586 scopus 로고    scopus 로고
    • Polyclonal b cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals
    • Tomaras, G. D. et al. Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals. J. Virol. 85, 11502-11519 (2011).
    • (2011) J. Virol , vol.85 , pp. 11502-11519
    • Tomaras, G.D.1
  • 42
    • 84906084946 scopus 로고    scopus 로고
    • Optimization and validation of the tzm-bl assay for standardized assessments of neutralizing antibodies against HIV-1
    • Sarzotti-Kelsoe, M. et al. Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1. J. Immunol. Methods 409, 131-146 (2014).
    • (2014) J. Immunol. Methods , vol.409 , pp. 131-146
    • Sarzotti-Kelsoe, M.1
  • 43
    • 73949127978 scopus 로고    scopus 로고
    • Tiered categorization of a diverse panel of HIV-1 env pseudoviruses for assessment of neutralizing antibodies
    • Seaman, M. S. et al. Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies. J. Virol. 84, 1439-1452 (2010).
    • (2010) J. Virol , vol.84 , pp. 1439-1452
    • Seaman, M.S.1
  • 44
    • 79960555557 scopus 로고    scopus 로고
    • High-throughput quantitative analysis of HIV-1 and siv-specific adcc-mediating antibody responses
    • Pollara, J. et al. High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses. Cytometry A 79, 603-612 (2011).
    • (2011) Cytometry A , vol.79 , pp. 603-612
    • Pollara, J.1
  • 45
    • 0030611643 scopus 로고    scopus 로고
    • Fc gammariiia-158v/f polymorphism influences the binding of igg by natural killer cell fc gammariiia, independently of the fc gammariiia-48l/r/h phenotype
    • Koene, H. R. et al. Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype. Blood 90, 1109-1114 (1997).
    • (1997) Blood , vol.90 , pp. 1109-1114
    • Koene, H.R.1
  • 46
    • 78049255341 scopus 로고    scopus 로고
    • Replication competent molecular clones of HIV-1 expressing renilla luciferase facilitate the analysis of antibody inhibition in pbmc
    • Edmonds, T. G. et al. Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC. Virology 408, 1-13 (2010).
    • (2010) Virology , vol.408 , pp. 1-13
    • Edmonds, T.G.1
  • 47
    • 84940978465 scopus 로고    scopus 로고
    • Association of HIV-1 envelope-specific breast milk iga responses with reduced risk of postnatal mother-to-child transmission of HIV-1
    • Pollara, J. et al. Association of HIV-1 envelope-specific breast milk IgA responses with reduced risk of postnatal mother-to-child transmission of HIV-1. J. Virol. 89, 9952-9961 (2015).
    • (2015) J. Virol , vol.89 , pp. 9952-9961
    • Pollara, J.1
  • 48
    • 0028131273 scopus 로고
    • Interleukin (il) 15 is a novel cytokine that activates human natural killer cells via components of the il-2 receptor
    • Carson, W. E. et al. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J. Exp. Med. 180, 1395-1403 (1994).
    • (1994) J. Exp. Med , vol.180 , pp. 1395-1403
    • Carson, W.E.1
  • 49
    • 79952310878 scopus 로고    scopus 로고
    • A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples
    • Ackerman, M. E. et al. A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. J. Immunol. Methods 366, 8-19 (2011).
    • (2011) J. Immunol. Methods , vol.366 , pp. 8-19
    • Ackerman, M.E.1
  • 50
    • 84984793166 scopus 로고    scopus 로고
    • Antibody-mediated internalization of infectious HIV-1 virions differs among antibody isotypes and subclasses
    • Tay, M. Z. et al. Antibody-mediated internalization of infectious HIV-1 virions differs among antibody isotypes and subclasses. PLoS Pathogens 12, e1005817 (2016).
    • (2016) PLoS Pathogens , vol.12 , pp. e1005817
    • Tay, M.Z.1
  • 51
    • 84867472665 scopus 로고    scopus 로고
    • High-throughput, multiplexed igg subclassing of antigen-specific antibodies from clinical samples
    • Brown, E. P. et al. High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples. J. Immunol. Methods 386, 117-123 (2012).
    • (2012) J. Immunol. Methods , vol.386 , pp. 117-123
    • Brown, E.P.1
  • 52
    • 84989873558 scopus 로고    scopus 로고
    • Igg binding characteristics of rhesus macaque fcgammar
    • Chan, Y. N. et al. IgG binding characteristics of rhesus macaque FcgammaR. J. Immunol. 197, 2936-2947 (2016).
    • (2016) J. Immunol , vol.197 , pp. 2936-2947
    • Chan, Y.N.1
  • 53
    • 84903776700 scopus 로고    scopus 로고
    • Highly parallel characterization of igg fc binding interactions
    • Boesch, A. W. et al. Highly parallel characterization of IgG Fc binding interactions. mAbs 6, 915-927 (2014).
    • (2014) MAbs , vol.6 , pp. 915-927
    • Boesch, A.W.1
  • 54
    • 84899105650 scopus 로고    scopus 로고
    • Polyfunctional fc-effector profiles mediated by igg subclass selection distinguish rv144 and vax003 vaccines
    • Chung, A. W. et al. Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines. Sci. Transl. Med. 6, 228ra238 (2014).
    • (2014) Sci. Transl. Med , vol.6 , pp. 228ra238
    • Chung, A.W.1
  • 55
    • 77950537175 scopus 로고    scopus 로고
    • Regularization paths for generalized linear models via coordinate descent
    • Friedman, J., Hastie, T. & Tibshirani, R. Regularization paths for generalized linear models via coordinate descent. J. Stat. Softw. 33, 1-22 (2010).
    • (2010) J. Stat. Softw , vol.33 , pp. 1-22
    • Friedman, J.1    Hastie, T.2    Tibshirani, R.3
  • 56
    • 77954676863 scopus 로고    scopus 로고
    • Permutation tests for studying classifier performance
    • Ojala, M. & Garriga, G. C. Permutation tests for studying classifier performance. J. Mach. Learn. Res. 11, 1833-1863 (2010).
    • (2010) J. Mach. Learn. Res , vol.11 , pp. 1833-1863
    • Ojala, M.1    Garriga, G.C.2
  • 57
    • 0000336139 scopus 로고
    • Regression models and life-tables
    • Cox, D. R. Regression models and life-tables. J. R. Stat. Soc. B 34, 187-+ (1972).
    • (1972) J. R. Stat. Soc. B , vol.34 , pp. 187
    • Cox, D.R.1
  • 59
    • 1942485113 scopus 로고
    • Polychoric and polyserial correlations
    • Drasgow, F. Polychoric and polyserial correlations. Encyclopedia Stat. 7, 68-74 (1986).
    • (1986) Encyclopedia Stat , vol.7 , pp. 68-74
    • Drasgow, F.1
  • 60
    • 0030069896 scopus 로고    scopus 로고
    • Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
    • Harrell, Jr. F. E., Lee, K. L. & Mark, D. B. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat. Med. 15, 361-387 (1996).
    • (1996) Stat. Med , vol.15 , pp. 361-387
    • Harrell, F.E.1    Lee, K.L.2    Mark, D.B.3
  • 61
    • 84918548024 scopus 로고    scopus 로고
    • Antibody light-chain-restricted recognition of the site of immune pressure in the rv144 HIV-1 vaccine trial is phylogenetically conserved
    • Wiehe, K. et al. Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved. Immunity 41, 909-918 (2014).
    • (2014) Immunity , vol.41 , pp. 909-918
    • Wiehe, K.1
  • 62
    • 85000360533 scopus 로고    scopus 로고
    • Reconstructing a b-cell clonal lineage. I. Statistical inference of unobserved ancestors
    • Kepler, T. B. Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors. F1000Res. 2, 103 (2013).
    • (2013) F1000Res , vol.2 , pp. 103
    • Kepler, T.B.1
  • 63
    • 77951949737 scopus 로고    scopus 로고
    • Soda2: A hidden markov model approach for identification of immunoglobulin rearrangements
    • Munshaw, S. & Kepler, T. B. SoDA2: a Hidden Markov Model approach for identification of immunoglobulin rearrangements. Bioinformatics 26, 867-872 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 867-872
    • Munshaw, S.1    Kepler, T.B.2
  • 64
    • 64949164763 scopus 로고    scopus 로고
    • High-throughput isolation of immunoglobulin genes from single human b cells and expression as monoclonal antibodies
    • Liao, H. X. et al. High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies. J. Virol. Methods 158, 171-179 (2009).
    • (2009) J. Virol. Methods , vol.158 , pp. 171-179
    • Liao, H.X.1
  • 65
    • 80055118908 scopus 로고    scopus 로고
    • Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated
    • Liao, H. X. et al. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. J. Exp. Med. 208, 2237-2249 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 2237-2249
    • Liao, H.X.1
  • 66
    • 84961356295 scopus 로고    scopus 로고
    • Identification of new regions in HIV-1 gp120 variable 2 and 3 loops that bind to alpha4beta7 integrin receptor
    • Peachman, K. K. et al. Identification of new regions in HIV-1 gp120 variable 2 and 3 loops that bind to alpha4beta7 integrin receptor. PLoS ONE 10, e0143895 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0143895
    • Peachman, K.K.1


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