메뉴 건너뛰기




Volumn 13, Issue 5, 2017, Pages

Drosophila as a model for homeostatic, antibacterial, and antiviral mechanisms in the gut

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 9; EPIDERMAL GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN RECEPTOR;

EID: 85020215852     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006277     Document Type: Review
Times cited : (55)

References (58)
  • 1
    • 84922481687 scopus 로고    scopus 로고
    • Immunity in Drosophila melanogaster—from microbial recognition to whole-organism physiology
    • 25421701
    • Buchon N, Silverman N, Cherry S, Immunity in Drosophila melanogaster—from microbial recognition to whole-organism physiology. Nat Rev Immunol. 2014;14: 796–810. doi: 10.1038/nri3763 25421701
    • (2014) Nat Rev Immunol , vol.14 , pp. 796-810
    • Buchon, N.1    Silverman, N.2    Cherry, S.3
  • 2
    • 84964397412 scopus 로고    scopus 로고
    • From pathogens to microbiota: How Drosophila intestinal stem cells react to gut microbes
    • 26855015
    • Bonfini A, Liu X, Buchon N, From pathogens to microbiota: How Drosophila intestinal stem cells react to gut microbes. Dev Comp Immunol. 2016;64: 22–38. doi: 10.1016/j.dci.2016.02.008 26855015
    • (2016) Dev Comp Immunol , vol.64 , pp. 22-38
    • Bonfini, A.1    Liu, X.2    Buchon, N.3
  • 3
    • 84937512699 scopus 로고    scopus 로고
    • Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut
    • 26146076
    • Dutta D, Dobson AJ, Houtz PL, Gläßer C, Revah J, Korzelius J, et al. Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut. Cell Rep. 2015;12: 346–358. doi: 10.1016/j.celrep.2015.06.009 26146076
    • (2015) Cell Rep , vol.12 , pp. 346-358
    • Dutta, D.1    Dobson, A.J.2    Houtz, P.L.3    Gläßer, C.4    Revah, J.5    Korzelius, J.6
  • 4
    • 34147172817 scopus 로고    scopus 로고
    • Native microbial colonization of Drosophila melanogaster and its use as a model of Enterococcus faecalis pathogenesis
    • 17220307
    • Cox CR, Gilmore MS, Native microbial colonization of Drosophila melanogaster and its use as a model of Enterococcus faecalis pathogenesis. Infection and Immunity. 2007;75: 1565–1576. doi: 10.1128/IAI.01496-06 17220307
    • (2007) Infection and Immunity , vol.75 , pp. 1565-1576
    • Cox, C.R.1    Gilmore, M.S.2
  • 5
    • 80053435147 scopus 로고    scopus 로고
    • Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System
    • Chandler J, Lang J, Bhatnagar S, Eisen J, Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System. PLoS Genet. 2011.
    • (2011) PLoS Genet
    • Chandler, J.1    Lang, J.2    Bhatnagar, S.3    Eisen, J.4
  • 6
    • 84903939893 scopus 로고    scopus 로고
    • Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology
    • American Society for Microbiology
    • Broderick NA, Buchon N, Lemaitre B, Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. MBio. American Society for Microbiology; 2014;5: e01117–14.
    • (2014) MBio , vol.5 , pp. e01117
    • Broderick, N.A.1    Buchon, N.2    Lemaitre, B.3
  • 7
    • 79959841282 scopus 로고    scopus 로고
    • Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster
    • 21631690,. Blackwell Publishing Ltd
    • Wong CNA, Ng P, Douglas AE, Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster. Environ Microbiol. Blackwell Publishing Ltd; 2011;13: 1889–1900. doi: 10.1111/j.1462-2920.2011.02511.x 21631690
    • (2011) Environ Microbiol , vol.13 , pp. 1889-1900
    • Wong, C.N.A.1    Ng, P.2    Douglas, A.E.3
  • 8
    • 84884675234 scopus 로고    scopus 로고
    • The inconstant gut microbiota of Drosophila species revealed by 16S rRNA gene analysis
    • 23719154
    • Wong AC-N, Chaston JM, Douglas AE, The inconstant gut microbiota of Drosophila species revealed by 16S rRNA gene analysis. ISME J. 2013;7: 1922–1932. doi: 10.1038/ismej.2013.86 23719154
    • (2013) ISME J , vol.7 , pp. 1922-1932
    • Wong, A.C.-N.1    Chaston, J.M.2    Douglas, A.E.3
  • 9
    • 84863870218 scopus 로고    scopus 로고
    • Gut-associated microbes of Drosophila melanogaster
    • 22572876
    • Broderick NA, Lemaitre B, Gut-associated microbes of Drosophila melanogaster. Gut Microbes. 2012;3: 307–321. doi: 10.4161/gmic.19896 22572876
    • (2012) Gut Microbes , vol.3 , pp. 307-321
    • Broderick, N.A.1    Lemaitre, B.2
  • 10
    • 80555143077 scopus 로고    scopus 로고
    • Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling
    • 22053049
    • Shin SC, Kim S-H, You H, Kim B, Kim AC, Lee K-A, et al. Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling. Science. 2011;334: 670–674. doi: 10.1126/science.1212782 22053049
    • (2011) Science , vol.334 , pp. 670-674
    • Shin, S.C.1    Kim, S.-H.2    You, H.3    Kim, B.4    Kim, A.C.5    Lee, K.-A.6
  • 11
    • 80052774197 scopus 로고    scopus 로고
    • Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing
    • 21907145
    • Storelli G, Defaye A, Erkosar B, Hols P, Royet J, Leulier F, Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing. Cell Metab. 2011;14: 403–414. doi: 10.1016/j.cmet.2011.07.012 21907145
    • (2011) Cell Metab , vol.14 , pp. 403-414
    • Storelli, G.1    Defaye, A.2    Erkosar, B.3    Hols, P.4    Royet, J.5    Leulier, F.6
  • 12
    • 84959017701 scopus 로고    scopus 로고
    • Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition
    • 26912894
    • Schwarzer M, Makki K, Storelli G, Machuca-Gayet I, Srutkova D, Hermanova P, et al. Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition. Science. 2016;351: 854–857. doi: 10.1126/science.aad8588 26912894
    • (2016) Science , vol.351 , pp. 854-857
    • Schwarzer, M.1    Makki, K.2    Storelli, G.3    Machuca-Gayet, I.4    Srutkova, D.5    Hermanova, P.6
  • 13
    • 70349617469 scopus 로고    scopus 로고
    • Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila
    • 19797770,. Cold Spring Harbor Lab
    • Buchon N, Broderick NA, Chakrabarti S, Lemaitre B, Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila. Genes Dev. Cold Spring Harbor Lab; 2009;23: 2333–2344. doi: 10.1101/gad.1827009 19797770
    • (2009) Genes Dev , vol.23 , pp. 2333-2344
    • Buchon, N.1    Broderick, N.A.2    Chakrabarti, S.3    Lemaitre, B.4
  • 14
    • 84892714390 scopus 로고    scopus 로고
    • PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan
    • 24439372
    • Guo L, Karpac J, Tran SL, Jasper H, PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan. Cell. 2014;156: 109–122. doi: 10.1016/j.cell.2013.12.018 24439372
    • (2014) Cell , vol.156 , pp. 109-122
    • Guo, L.1    Karpac, J.2    Tran, S.L.3    Jasper, H.4
  • 15
    • 85011945190 scopus 로고    scopus 로고
    • Preventing Age-Related Decline of Gut Compartmentalization Limits Microbiota Dysbiosis and Extends Lifespan
    • 26867182
    • Li H, Qi Y, Jasper H, Preventing Age-Related Decline of Gut Compartmentalization Limits Microbiota Dysbiosis and Extends Lifespan. Cell Host Microbe. 2016;19: 240–253. doi: 10.1016/j.chom.2016.01.008 26867182
    • (2016) Cell Host Microbe , vol.19 , pp. 240-253
    • Li, H.1    Qi, Y.2    Jasper, H.3
  • 16
    • 84992752714 scopus 로고    scopus 로고
    • Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality.—PubMed—NCBI
    • 26321641
    • Clark RI, Salazar A, Yamada R, Fitz-Gibbon S, Morselli M, Alcaraz J, et al. Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality.—PubMed—NCBI. Cell Rep. 2015;12: 1656–1667. doi: 10.1016/j.celrep.2015.08.004 26321641
    • (2015) Cell Rep , vol.12 , pp. 1656-1667
    • Clark, R.I.1    Salazar, A.2    Yamada, R.3    Fitz-Gibbon, S.4    Morselli, M.5    Alcaraz, J.6
  • 17
    • 84908321872 scopus 로고    scopus 로고
    • Transient adult microbiota, gut homeostasis and longevity: novel insights from the Drosophila model
    • 24983497
    • Erkosar B, Leulier F, Transient adult microbiota, gut homeostasis and longevity: novel insights from the Drosophila model. FEBS Lett. 2014;588: 4250–4257. doi: 10.1016/j.febslet.2014.06.041 24983497
    • (2014) FEBS Lett , vol.588 , pp. 4250-4257
    • Erkosar, B.1    Leulier, F.2
  • 18
    • 48649085941 scopus 로고    scopus 로고
    • PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling
    • 18692774
    • Lhocine N, Ribeiro PS, Buchon N, Wepf A, Wilson R, Tenev T, et al. PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling. Cell Host Microbe. 2008;4: 147–158. doi: 10.1016/j.chom.2008.07.004 18692774
    • (2008) Cell Host Microbe , vol.4 , pp. 147-158
    • Lhocine, N.1    Ribeiro, P.S.2    Buchon, N.3    Wepf, A.4    Wilson, R.5    Tenev, T.6
  • 19
    • 10744230355 scopus 로고    scopus 로고
    • The homeobox gene Caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia
    • 14673153
    • Ryu J-H, Nam K-B, Oh C-T, Nam H-J, Kim S-H, Yoon J-H, et al. The homeobox gene Caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia. Mol Cell Biol. 2004;24: 172–185. doi: 10.1128/MCB.24.1.172-185.2004 14673153
    • (2004) Mol Cell Biol , vol.24 , pp. 172-185
    • Ryu, J.-H.1    Nam, K.-B.2    Oh, C.-T.3    Nam, H.-J.4    Kim, S.-H.5    Yoon, J.-H.6
  • 20
    • 82055177179 scopus 로고    scopus 로고
    • Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection
    • 22118526
    • Paredes JC, Welchman DP, Poidevin M, Lemaitre B, Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection. Immunity. 2011;35: 770–779. doi: 10.1016/j.immuni.2011.09.018 22118526
    • (2011) Immunity , vol.35 , pp. 770-779
    • Paredes, J.C.1    Welchman, D.P.2    Poidevin, M.3    Lemaitre, B.4
  • 21
    • 84995575844 scopus 로고    scopus 로고
    • Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense
    • 27631699
    • Morris O, Liu X, Domingues C, Runchel C, Chai A, Basith S, et al. Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense. Cell Host Microbe. 2016;20: 283–295. doi: 10.1016/j.chom.2016.08.003 27631699
    • (2016) Cell Host Microbe , vol.20 , pp. 283-295
    • Morris, O.1    Liu, X.2    Domingues, C.3    Runchel, C.4    Chai, A.5    Basith, S.6
  • 23
    • 61749104447 scopus 로고    scopus 로고
    • Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity
    • 19289084
    • Ha E-M, Lee K-A, Park SH, Kim S-H, Nam H-J, Lee H-Y, et al. Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity. Dev Cell. 2009;16: 386–397. doi: 10.1016/j.devcel.2008.12.015 19289084
    • (2009) Dev Cell , vol.16 , pp. 386-397
    • Ha, E.-M.1    Lee, K.-A.2    Park, S.H.3    Kim, S.-H.4    Nam, H.-J.5    Lee, H.-Y.6
  • 24
    • 84877723813 scopus 로고    scopus 로고
    • Bacterial-Derived Uracil as a Modulator of Mucosal Immunity and Gut-Microbe Homeostasis in Drosophila
    • 23663779,.. Elsevier
    • Lee K-A, Kim S-H, Kim E-K, Ha E-M, You H, Kim B, et al. Bacterial-Derived Uracil as a Modulator of Mucosal Immunity and Gut-Microbe Homeostasis in Drosophila. Cell. Elsevier; 2013;153: 797–811. doi: 10.1016/j.cell.2013.04.009 23663779
    • (2013) Cell , vol.153 , pp. 797-811
    • Lee, K.-A.1    Kim, S.-H.2    Kim, E.-K.3    Ha, E.-M.4    You, H.5    Kim, B.6
  • 25
    • 84888864785 scopus 로고    scopus 로고
    • Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species
    • 24141879
    • Jones RM, Luo L, Ardita CS, Richardson AN, Kwon YM, Mercante JW, et al. Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species. EMBO J. 2013;32: 3017–3028. doi: 10.1038/emboj.2013.224 24141879
    • (2013) EMBO J , vol.32 , pp. 3017-3028
    • Jones, R.M.1    Luo, L.2    Ardita, C.S.3    Richardson, A.N.4    Kwon, Y.M.5    Mercante, J.W.6
  • 26
    • 33747586778 scopus 로고    scopus 로고
    • An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity
    • 16858400
    • Ryu J-H, Ha E-M, Oh C-T, Seol J-H, Brey PT, Jin I, et al. An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity. EMBO J. 2006;25: 3693–3701. doi: 10.1038/sj.emboj.7601233 16858400
    • (2006) EMBO J , vol.25 , pp. 3693-3701
    • Ryu, J.-H.1    Ha, E.-M.2    Oh, C.-T.3    Seol, J.-H.4    Brey, P.T.5    Jin, I.6
  • 27
    • 84876414806 scopus 로고    scopus 로고
    • The gut microbiota—masters of host development and physiology.—PubMed—NCBI
    • Sommer F, Bäckhed F, The gut microbiota—masters of host development and physiology.—PubMed—NCBI. Nature Reviews Microbiology. 2013;11: 227–238.
    • (2013) Nature Reviews Microbiology , vol.11 , pp. 227-238
    • Sommer, F.1    Bäckhed, F.2
  • 28
    • 84955513503 scopus 로고    scopus 로고
    • Reparative inflammation takes charge of tissue regeneration
    • 26791721
    • Karin M, Clevers H, Reparative inflammation takes charge of tissue regeneration. Nature. 2016;529: 307–315. doi: 10.1038/nature17039 26791721
    • (2016) Nature , vol.529 , pp. 307-315
    • Karin, M.1    Clevers, H.2
  • 29
    • 84882709450 scopus 로고    scopus 로고
    • Gut homeostasis in a microbial world: insights from Drosophila melanogaster
    • Buchon N, Broderick NA, Lemaitre B, Gut homeostasis in a microbial world: insights from Drosophila melanogaster. Nat Rev Micro. 2013;11: 615–626.
    • (2013) Nat Rev Micro , vol.11 , pp. 615-626
    • Buchon, N.1    Broderick, N.A.2    Lemaitre, B.3
  • 30
    • 84865108178 scopus 로고    scopus 로고
    • Peptidoglycan Sensing by the Receptor PGRP-LE in the Drosophila Gut Induces Immune Responses to Infectious Bacteria and Tolerance to Microbiota
    • 22901536
    • Bosco-Drayon V, Poidevin M, Boneca IG, Narbonne-Reveau K, Royet J, Charroux B, Peptidoglycan Sensing by the Receptor PGRP-LE in the Drosophila Gut Induces Immune Responses to Infectious Bacteria and Tolerance to Microbiota. Cell Host Microbe. 2012;12: 153–165. doi: 10.1016/j.chom.2012.06.002 22901536
    • (2012) Cell Host Microbe , vol.12 , pp. 153-165
    • Bosco-Drayon, V.1    Poidevin, M.2    Boneca, I.G.3    Narbonne-Reveau, K.4    Royet, J.5    Charroux, B.6
  • 31
    • 84864807751 scopus 로고    scopus 로고
    • Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE
    • Neyen C, Poidevin M, Roussel A, Lemaitre B, Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE. J Immunol. 2012.
    • (2012) J Immunol
    • Neyen, C.1    Poidevin, M.2    Roussel, A.3    Lemaitre, B.4
  • 32
    • 84864861276 scopus 로고    scopus 로고
    • The role of neutrophils during intestinal inflammation
    • 22491176
    • Fournier BM, Parkos CA, The role of neutrophils during intestinal inflammation. Mucosal immunology. 2012;5: 354–366. doi: 10.1038/mi.2012.24 22491176
    • (2012) Mucosal immunology , vol.5 , pp. 354-366
    • Fournier, B.M.1    Parkos, C.A.2
  • 34
    • 84992754324 scopus 로고    scopus 로고
    • The Drosophila CD36 Homologue croquemort Is Required to Maintain Immune and Gut Homeostasis during Development and Aging.—PubMed—NCBI
    • 27780230
    • Guillou A, Troha K, Wang H, Franc NC, Buchon N, O'Riordan M, The Drosophila CD36 Homologue croquemort Is Required to Maintain Immune and Gut Homeostasis during Development and Aging.—PubMed—NCBI. PLoS Pathog. 2016;12: e1005961. doi: 10.1371/journal.ppat.1005961 27780230
    • (2016) PLoS Pathog , vol.12 , pp. e1005961
    • Guillou, A.1    Troha, K.2    Wang, H.3    Franc, N.C.4    Buchon, N.5    O'Riordan, M.6
  • 35
    • 84930160218 scopus 로고    scopus 로고
    • Haemocytes control stem cell activity in the Drosophila intestine
    • 26005834
    • Ayyaz A, Li H, Jasper H, Haemocytes control stem cell activity in the Drosophila intestine. Nat Cell Biol. 2015;17: 736–748. doi: 10.1038/ncb3174 26005834
    • (2015) Nat Cell Biol , vol.17 , pp. 736-748
    • Ayyaz, A.1    Li, H.2    Jasper, H.3
  • 37
    • 60649091298 scopus 로고    scopus 로고
    • Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation
    • 19218090
    • Buchon N, Broderick NA, Poidevin M, Pradervand S, Lemaitre B, Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. Cell Host Microbe. 2009;5: 200–211. doi: 10.1016/j.chom.2009.01.003 19218090
    • (2009) Cell Host Microbe , vol.5 , pp. 200-211
    • Buchon, N.1    Broderick, N.A.2    Poidevin, M.3    Pradervand, S.4    Lemaitre, B.5
  • 38
    • 67549133157 scopus 로고    scopus 로고
    • Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
    • 19563763
    • Jiang H, Patel PH, Kohlmaier A, Grenley MO, Mcewen DG, Edgar BA, Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell. 2009;137: 1343–1355. doi: 10.1016/j.cell.2009.05.014 19563763
    • (2009) Cell , vol.137 , pp. 1343-1355
    • Jiang, H.1    Patel, P.H.2    Kohlmaier, A.3    Grenley, M.O.4    Mcewen, D.G.5    Edgar, B.A.6
  • 39
    • 78650977190 scopus 로고    scopus 로고
    • ,,,,,, EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila
    • 21167805
    • Jiang H, Grenley MO, Bravo M-J, Blumhagen RZ, Edgar BA,,,,EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila. Cell Stem Cell. 2011;8: 84–95. doi: 10.1016/j.stem.2010.11.026 21167805
    • (2011) Cell Stem Cell , vol.8 , pp. 84-95
    • Jiang, H.1    Grenley, M.O.2    Bravo, M.-J.3    Blumhagen, R.Z.4    Edgar, B.A.5
  • 40
    • 78650397479 scopus 로고    scopus 로고
    • Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection
    • 21176204,. BioMed Central Ltd
    • Buchon N, Broderick NA, Kuraishi T, Lemaitre B, Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol. BioMed Central Ltd; 2010;8: 152. doi: 10.1186/1741-7007-8-152 21176204
    • (2010) BMC Biol , vol.8 , pp. 152
    • Buchon, N.1    Broderick, N.A.2    Kuraishi, T.3    Lemaitre, B.4
  • 42
    • 84951283991 scopus 로고    scopus 로고
    • Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
    • 26649819
    • Lindemans CA, Calafiore M, Mertelsmann AM, O’Connor MH, Dudakov JA, Jenq RR, et al. Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration. Nature. 2015;528: 560–564. doi: 10.1038/nature16460 26649819
    • (2015) Nature , vol.528 , pp. 560-564
    • Lindemans, C.A.1    Calafiore, M.2    Mertelsmann, A.M.3    O’Connor, M.H.4    Dudakov, J.A.5    Jenq, R.R.6
  • 45
    • 84945892538 scopus 로고    scopus 로고
    • Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer
    • 26503053,. Nature Research
    • Gregorieff A, Liu Y, Inanlou MR, Khomchuk Y, Wrana JL, Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer. Nature. Nature Research; 2015;526: 715–718. doi: 10.1038/nature15382 26503053
    • (2015) Nature , vol.526 , pp. 715-718
    • Gregorieff, A.1    Liu, Y.2    Inanlou, M.R.3    Khomchuk, Y.4    Wrana, J.L.5
  • 47
    • 84949798263 scopus 로고    scopus 로고
    • Signal integration by Ca2+ regulates intestinal stem-cell activity
    • 26633624
    • Deng H, Gerencser AA, Jasper H, Signal integration by Ca2+ regulates intestinal stem-cell activity. Nature. 2015;528: 212–217. doi: 10.1038/nature16170 26633624
    • (2015) Nature , vol.528 , pp. 212-217
    • Deng, H.1    Gerencser, A.A.2    Jasper, H.3
  • 48
    • 84988447946 scopus 로고    scopus 로고
    • Discovery of novel targets for antivirals: learning from flies
    • 27657660
    • Martins N, Imler J-L, Meignin C, Discovery of novel targets for antivirals: learning from flies. Curr Opin Virol. 2016;20: 64–70. doi: 10.1016/j.coviro.2016.09.005 27657660
    • (2016) Curr Opin Virol , vol.20 , pp. 64-70
    • Martins, N.1    Imler, J.-L.2    Meignin, C.3
  • 49
    • 84969975020 scopus 로고    scopus 로고
    • The diversity of insect antiviral immunity: insights from viruses
    • 27232381
    • Marques JT, Imler J-L, The diversity of insect antiviral immunity: insights from viruses. Current Opinion in Microbiology. 2016;32: 71–76. doi: 10.1016/j.mib.2016.05.002 27232381
    • (2016) Current Opinion in Microbiology , vol.32 , pp. 71-76
    • Marques, J.T.1    Imler, J.-L.2
  • 50
    • 84919665943 scopus 로고    scopus 로고
    • The Toll-dorsal pathway is required for resistance to viral oral infection in Drosophila
    • 25473839
    • Ferreira ÁG, Naylor H, Esteves SS, Pais IS, Martins NE, Teixeira L, The Toll-dorsal pathway is required for resistance to viral oral infection in Drosophila. PLoS Pathog. 2014;10: e1004507. doi: 10.1371/journal.ppat.1004507 25473839
    • (2014) PLoS Pathog , vol.10 , pp. e1004507
    • Ferreira, Á.G.1    Naylor, H.2    Esteves, S.S.3    Pais, I.S.4    Martins, N.E.5    Teixeira, L.6
  • 52
    • 84946024949 scopus 로고    scopus 로고
    • Wolbachia-Mediated Antiviral Protection in Drosophila Larvae and Adults following Oral Infection
    • 26407882
    • Stevanovic AL, Arnold PA, Johnson KN, Goodrich-Blai H, Wolbachia-Mediated Antiviral Protection in Drosophila Larvae and Adults following Oral Infection. Applied and Environmental Microbiology. 2015;81: 8215–8223. doi: 10.1128/AEM.02841-15 26407882
    • (2015) Applied and Environmental Microbiology , vol.81 , pp. 8215-8223
    • Stevanovic, A.L.1    Arnold, P.A.2    Johnson, K.N.3    Goodrich-Blai, H.4
  • 53
    • 84970011985 scopus 로고    scopus 로고
    • Analysis of the Contribution of Hemocytes and Autophagy to Drosophila Antiviral Immunity
    • 27009948,.. American Society for Microbiology
    • Lamiable O, Arnold J, de Faria IJDS, Olmo RP, Bergami F, Meignin C, et al. Analysis of the Contribution of Hemocytes and Autophagy to Drosophila Antiviral Immunity. J Virol. American Society for Microbiology; 2016;90: 5415–5426. doi: 10.1128/JVI.00238-16 27009948
    • (2016) J Virol , vol.90 , pp. 5415-5426
    • Lamiable, O.1    Arnold, J.2    de Faria, I.J.D.S.3    Olmo, R.P.4    Bergami, F.5    Meignin, C.6
  • 54
    • 58149143149 scopus 로고    scopus 로고
    • The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster. Keller L, editor
    • Teixeira L, Ferreira A, Ashburner M, The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster. Keller L, editor. PLoS Biol. 2008;6: e2.
    • (2008) PLoS Biol , vol.6 , pp. e2
    • Teixeira, L.1    Ferreira, A.2    Ashburner, M.3
  • 55
    • 55349146939 scopus 로고    scopus 로고
    • Wolbachia and virus protection in insects
    • 18974344
    • Hedges LM, Brownlie JC, O'Neill SL, Johnson KN, Wolbachia and virus protection in insects. Science. 2008;322: 702. doi: 10.1126/science.1162418 18974344
    • (2008) Science , vol.322 , pp. 702
    • Hedges, L.M.1    Brownlie, J.C.2    O'Neill, S.L.3    Johnson, K.N.4
  • 56
    • 84991730777 scopus 로고    scopus 로고
    • Wolbachia: A biological control strategy against arboviral diseases
    • 27681542
    • Mohanty I, Rath A, Mahapatra N, Hazra RK, Wolbachia: A biological control strategy against arboviral diseases. J Vector Borne Dis. 2016;53: 199–207. 27681542
    • (2016) J Vector Borne Dis , vol.53 , pp. 199-207
    • Mohanty, I.1    Rath, A.2    Mahapatra, N.3    Hazra, R.K.4
  • 57
    • 84954439150 scopus 로고    scopus 로고
    • Viruses and the Microbiota
    • 25821837
    • Robinson CM, Pfeiffer JK, Viruses and the Microbiota. Annu Rev Virol. 2014;1: 55–69. doi: 10.1146/annurev-virology-031413-085550 25821837
    • (2014) Annu Rev Virol , vol.1 , pp. 55-69
    • Robinson, C.M.1    Pfeiffer, J.K.2
  • 58
    • 84947426731 scopus 로고    scopus 로고
    • Microbiota-Dependent Priming of Antiviral Intestinal Immunity in Drosophila
    • 26567510
    • Sansone CL, Cohen J, Yasunaga A, Xu J, Osborn G, Subramanian H, et al. Microbiota-Dependent Priming of Antiviral Intestinal Immunity in Drosophila. Cell Host Microbe. 2015;18: 571–581. doi: 10.1016/j.chom.2015.10.010 26567510
    • (2015) Cell Host Microbe , vol.18 , pp. 571-581
    • Sansone, C.L.1    Cohen, J.2    Yasunaga, A.3    Xu, J.4    Osborn, G.5    Subramanian, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.