Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease

American Journal of Human Genetics

Volumn 100, Issue 6, 2017, Pages 940-953

  Ko, Yi An ^a   Yi, Huiguang ^a   Qiu, Chengxiang ^a   Huang, Shizheng ^a   Park, Jihwan ^a   Ledo, Nora ^a   Köttgen, Anna ^b   Li, Hongzhe ^c   Rader, Daniel J ^c   Pack, Michael A ^a   Brown, Christopher D ^c   Susztak, Katalin ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

CKD; eQTL; gene network; gene regulation; GWAS; kidney

Indexed keywords

HISTONE DEACETYLASE 1; INTERFERON REGULATORY FACTOR 1; RNA; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR ZEB1; BETA MANNOSIDASE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CBX3 GENE; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE SILENCING; GENETIC REGULATION; GENETIC VARIABILITY; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMAN; HUMAN TISSUE; KDM5B GENE; KIDNEY CORTEX; KIDNEY FUNCTION; KIDNEY TISSUE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS; RNA SEQUENCE; SIX5 GENE; TRANSCRIPTION INITIATION SITE; ZEBRA FISH; ANIMAL; GENE EXPRESSION REGULATION; GENE LINKAGE DISEQUILIBRIUM; GENE REGULATORY NETWORK; GENETICS; KIDNEY; KIDNEY DISEASE; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; QUANTITATIVE TRAIT; REPRODUCIBILITY; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; BASE SEQUENCE; BETA-MANNOSIDASE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GENE REGULATORY NETWORKS; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; KIDNEY; KIDNEY DISEASES; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE; REPRODUCIBILITY OF RESULTS; ZEBRAFISH;

EID: 85020079716     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2017.05.004     Document Type: Article

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