Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases

Human Molecular Genetics

Volumn 24, Issue 12, 2015, Pages 3305-3313

  Guo, Hui ^a,b   Fortune, Mary D ^a   Burren, Oliver S ^a   Schofield, Ellen ^a   Todd, John A ^a   Wallace, Chris ^a,c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM15 GENE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE THYROID DISEASE; B LYMPHOCYTE; CARD9 GENE; CASE CONTROL STUDY; CELIAC DISEASE; CELLS BY BODY ANATOMY; CHROMOSOME 15Q; CONTROLLED STUDY; CROHN DISEASE; CTSH GENE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC REGULATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; LTBR GENE; MAJOR CLINICAL STUDY; MONOCYTE; MULTIPLE SCLEROSIS; NARCOLEPSY; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PSORIASIS; QUANTITATIVE TRAIT LOCUS; RGS1 GENE; RHEUMATOID ARTHRITIS; SYNGR1 GENE; THYROID DISEASE; ULCERATIVE COLITIS; BAYES THEOREM; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; QUANTITATIVE TRAIT;

BAYES THEOREM; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNE SYSTEM DISEASES; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE;

EID: 84930422605     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv077     Document Type: Article

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