Molecular insights into the differences in anti-inflammatory activities of green tea catechins on IL-1β signaling in rheumatoid arthritis synovial fibroblasts

Toxicology and Applied Pharmacology

Volumn 329, Issue , 2017, Pages 112-120

  Fechtner, Sabrina ^a   Singh, Anil ^a   Chourasia, Mukesh ^b   Ahmed, Salahuddin ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b Department of Biotechnology   (India)

Author keywords

Catechins; EGC; EGCG; Green tea; Inflammation; Rheumatoid arthritis

Indexed keywords

CATECHIN; CYCLOOXYGENASE 2; EPICATECHIN; EPIGALLOCATECHIN; GELATINASE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; ANTIINFLAMMATORY AGENT; ANTIRHEUMATIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; EPIGALLOCATECHIN GALLATE; GALLOCATECHIN; IL1B PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MMP2 PROTEIN, HUMAN; PROTEIN BINDING; PROTEIN C JUN; PROTEIN KINASE INHIBITOR; TEA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG SCREENING; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MOLECULAR DOCKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; TEA; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; ARTHRITIS, RHEUMATOID; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVE SITE; IMMUNOLOGY; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; PHOSPHORYLATION; PHYTOTHERAPY; SIGNAL TRANSDUCTION; SYNOVIUM;

ANTI-INFLAMMATORY AGENTS; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CATALYTIC DOMAIN; CATECHIN; CELLS, CULTURED; CYCLOOXYGENASE 2 INHIBITORS; FIBROBLASTS; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; MAP KINASE KINASE KINASES; MATRIX METALLOPROTEINASE 2; MOLECULAR DOCKING SIMULATION; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PHYTOTHERAPY; PLANTS, MEDICINAL; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-JUN; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; TEA;

EID: 85020036401     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2017.05.016     Document Type: Article

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