Characterization of TauC3 antibody and demonstration of its potential to block tau propagation

PLoS ONE

Volumn 12, Issue 5, 2017, Pages

  Nicholls, Samantha B ^a   Devos, Sarah L ^a   Commins, Caitlin ^a   Nobuhara, Chloe ^a   Bennett, Rachel E ^a   Corjuc, Diana L ^a   Maury, Eduardo ^a   Eftekharzadeh, Bahareh ^a   Akingbade, Ololade ^a   Fan, Zhanyun ^a   Roe, Allyson D ^a   Takeda, Shuko ^a   Wegmann, Susanne ^a   Hyman, Bradley T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN ANTIBODY; PROTEIN TAUC3 ANTIBODY; TAU PROTEIN; UNCLASSIFIED DRUG; ANTIBODY; CASP3 PROTEIN, HUMAN; CASPASE 3;

ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MISFOLDING; PROTEIN PURIFICATION; SURFACE PLASMON RESONANCE; WESTERN BLOTTING; ANTIBODY SPECIFICITY; BRAIN; CELL LINE; CHEMISTRY; IMMUNOLOGY; METABOLISM; MIDDLE AGED; NEUROFIBRILLARY TANGLE; PROTEIN FOLDING; VERY ELDERLY;

AGED, 80 AND OVER; ALZHEIMER DISEASE; ANTIBODIES; ANTIBODY SPECIFICITY; BRAIN; CASPASE 3; CELL LINE; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROFIBRILLARY TANGLES; PROTEIN FOLDING; TAU PROTEINS;

EID: 85019967130     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0177914     Document Type: Article

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