Architecture of the human interactome defines protein communities and disease networks

Nature

Volumn 545, Issue 7655, 2017, Pages 505-509

  Huttlin, Edward L ^a   Bruckner, Raphael J ^a   Paulo, Joao A ^a   Cannon, Joe R ^a   Ting, Lily ^a   Baltier, Kurt ^a   Colby, Greg ^a   Gebreab, Fana ^a   Gygi, Melanie P ^a   Parzen, Hannah ^a   Szpyt, John ^a   Tam, Stanley ^a   Zarraga, Gabriela ^a   Pontano Vaites, Laura ^a   Swarup, Sharan ^a   White, Anne E ^a   Schweppe, Devin K ^a   Rad, Ramin ^a   Erickson, Brian K ^a   Obar, Robert A ^a,b   Guruharsha, K G ^b   Li, Kejie ^b   Artavanis Tsakonas, Spyros ^a,b   Gygi, Steven P ^a   Wade Harper, J ^a   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CULLIN; PROTEIN; PROTEOME;

ARCHITECTURE; CELLS AND CELL COMPONENTS; DISEASE; GENOME; PHYSIOLOGY; PROTEIN; PROTEOMICS;

AFFINITY PURIFICATION MASS SPECTROMETRY; ARTICLE; BARDET BIEDL SYNDROME; BIOPLEX 2.0; CELLULAR DISTRIBUTION; CONGENITAL DISORDER; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DISEASES; FEMALE; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN CELL; HYPERTENSION; IMMUNOPRECIPITATION; MASS SPECTROMETRY; NEOPLASM; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; CELL FUNCTION; CHEMISTRY; GENETICS; HUMAN GENOME; INTRACELLULAR SPACE; MARKOV CHAIN; METABOLISM; MOLECULAR GENETICS; PROTEIN DATABASE;

CELL PHYSIOLOGICAL PHENOMENA; DATABASES, PROTEIN; DISEASE; GENOME, HUMAN; HUMANS; INTRACELLULAR SPACE; MARKOV CHAINS; MASS SPECTROMETRY; MOLECULAR SEQUENCE ANNOTATION; OPEN READING FRAMES; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS; PROTEOME;

EID: 85019703671     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature22366     Document Type: Article

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