Modified Panax ginseng extract regulates autophagy by AMPK signaling in A549 human lung cancer cells

Oncology Reports

Volumn 37, Issue 6, 2017, Pages 3287-3296

  Yoo, Hwa Seung ^a   Kim, Jung Min ^b   Jo, Eunbi ^c   Cho, Chong Kwan ^a   Lee, Seung Yeul ^c   Kang, Hwan Su ^c   Lee, Min Goo ^d   Yang, Pei Ying ^e   Jang, Ik Soon ^c,e  

^a Daejeon University   (South Korea)

^b Genoplan Inc   (South Korea)

^c Korea Basic Science Institute (KBSI)   (South Korea)

^d Korea University College of Medicine   (South Korea)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

Akt mTOR pathway; AMPK pathway; Autophagy; NSCLC cells

Indexed keywords

ADENYLATE KINASE; GINSENG EXTRACT; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; BECLIN 1; EIF4EBP1 PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, HUMAN; PHOSPHOPROTEIN; PLANT EXTRACT; PRKAA1 PROTEIN, HUMAN; SAPONIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG CANCER CELL LINE; MICROARRAY ANALYSIS; MITOSIS INHIBITION; NON SMALL CELL LUNG CANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; A-549 CELL LINE; CHEMISTRY; DRUG EFFECTS; GENETICS; LUNG TUMOR; METABOLISM; PANAX; PATHOLOGY;

A549 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMP-ACTIVATED PROTEIN KINASES; AUTOPHAGY; BECLIN-1; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MICROTUBULE-ASSOCIATED PROTEINS; PANAX; PHOSPHOPROTEINS; PLANT EXTRACTS; SAPONINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 85019566592     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2017.5590     Document Type: Article

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