메뉴 건너뛰기




Volumn 35, Issue , 2017, Pages 83-88

Immunotherapeutic properties of chemotherapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; BORTEZOMIB; CISPLATIN; CYCLOPHOSPHAMIDE; DASATINIB; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IMATINIB; IRINOTECAN; OXALIPLATIN; PACLITAXEL; TRASTUZUMAB; ANTINEOPLASTIC AGENT;

EID: 85019555841     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2017.05.003     Document Type: Review
Times cited : (23)

References (55)
  • 3
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • Schreiber, R.D., Old, L.J., Smyth, M.J., Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science (80-.) 331 (2011), 1565–1570.
    • (2011) Science (80-.) , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 4
    • 0014046848 scopus 로고
    • Inhibition of in vitro lymphocyte transformation chemotherapy in Man1
    • Hersh, E.M., Oppenheim, J., Inhibition of in vitro lymphocyte transformation chemotherapy in Man1. Cancer Res. 27 (1967), 98–105.
    • (1967) Cancer Res. , vol.27 , pp. 98-105
    • Hersh, E.M.1    Oppenheim, J.2
  • 5
    • 0015846828 scopus 로고
    • Adriamycin and daunorubicin: a comparison of antitumor activities and tissue uptake in mice following immunosuppression
    • Schwartz, H.S., Grindey, G.B., Adriamycin and daunorubicin: a comparison of antitumor activities and tissue uptake in mice following immunosuppression. Cancer Res. 33 (1973), 1837–1844.
    • (1973) Cancer Res. , vol.33 , pp. 1837-1844
    • Schwartz, H.S.1    Grindey, G.B.2
  • 6
    • 84890111958 scopus 로고    scopus 로고
    • Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer
    • Bracci, L., Schiavoni, G., Sistigu, A., Belardelli, F., Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer. Cell Death Differ. 21 (2014), 15–25.
    • (2014) Cell Death Differ. , vol.21 , pp. 15-25
    • Bracci, L.1    Schiavoni, G.2    Sistigu, A.3    Belardelli, F.4
  • 7
    • 84930183507 scopus 로고    scopus 로고
    • PRRs are watching you: localization of innate sensing and signaling regulators
    • Chow, J., Franz, K.M., Kagan, J.C., PRRs are watching you: localization of innate sensing and signaling regulators. Virology 479:480 (2015), 104–109.
    • (2015) Virology , vol.479 , Issue.480 , pp. 104-109
    • Chow, J.1    Franz, K.M.2    Kagan, J.C.3
  • 10
    • 79551523389 scopus 로고    scopus 로고
    • Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis
    • Schiavoni, G., Sistigu, A., Valentini, M., Mattei, F., Sestili, P., Spadaro, F., Sanchez, M., Lorenzi, S., D'Urso, M.T., Belardelli, F., et al. Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis. Cancer Res. 71 (2011), 768–778.
    • (2011) Cancer Res. , vol.71 , pp. 768-778
    • Schiavoni, G.1    Sistigu, A.2    Valentini, M.3    Mattei, F.4    Sestili, P.5    Spadaro, F.6    Sanchez, M.7    Lorenzi, S.8    D'Urso, M.T.9    Belardelli, F.10
  • 17
    • 84947763610 scopus 로고    scopus 로고
    • Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1
    • This study reveals, by identifying candidate genetic defects in cancer patients treated with chemotherapy, the importance of FRP1 signaling in chemotherapy-induced anticancer immune responses.
    • Vacchelli, E., Ma, Y., Baracco, E.E., Sistigu, A., Enot, D.P., Pietrocola, F., Yang, H., Adjemian, S., Chaba, K., Semeraro, M., et al. Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1. Science (80-.) 350 (2015), 972–978 This study reveals, by identifying candidate genetic defects in cancer patients treated with chemotherapy, the importance of FRP1 signaling in chemotherapy-induced anticancer immune responses.
    • (2015) Science (80-.) , vol.350 , pp. 972-978
    • Vacchelli, E.1    Ma, Y.2    Baracco, E.E.3    Sistigu, A.4    Enot, D.P.5    Pietrocola, F.6    Yang, H.7    Adjemian, S.8    Chaba, K.9    Semeraro, M.10
  • 20
    • 15944410592 scopus 로고    scopus 로고
    • Inhibition of CD4 + 25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
    • Lutsiak, M.E.C., Semnani, R.T., De Pascalis, R., Kashmiri, S.V.S., Schlom, J., Sabzevari, H., Inhibition of CD4 + 25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood 105 (2005), 2862–2868.
    • (2005) Blood , vol.105 , pp. 2862-2868
    • Lutsiak, M.E.C.1    Semnani, R.T.2    De Pascalis, R.3    Kashmiri, S.V.S.4    Schlom, J.5    Sabzevari, H.6
  • 22
    • 84955118284 scopus 로고    scopus 로고
    • Low dose cyclophosphamide: mechanisms of T cell modulation
    • Madondo, M.T., Quinn, M., Plebanski, M., Low dose cyclophosphamide: mechanisms of T cell modulation. Cancer Treat. Rev. 42 (2016), 3–9.
    • (2016) Cancer Treat. Rev. , vol.42 , pp. 3-9
    • Madondo, M.T.1    Quinn, M.2    Plebanski, M.3
  • 24
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki, E., Kapoor, V., Jassar, A.S., Kaiser, L.R., Albelda, S.M., Gemcitabine selectively eliminates splenic Gr-1+/CD11b + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 11 (2005), 6713–6721.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 25
    • 77951086882 scopus 로고    scopus 로고
    • G. hiringhelli F: 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
    • Vincent, J., Mignot, G., Chalmin, F., Ladoire, S., Bruchard, M., Chevriaux, A., Martin, F., Apetoh, L., Rébé C., G. hiringhelli F: 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res. 70 (2010), 3052–3061.
    • (2010) Cancer Res. , vol.70 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3    Ladoire, S.4    Bruchard, M.5    Chevriaux, A.6    Martin, F.7    Apetoh, L.8    Rébé, C.9
  • 26
    • 84874232680 scopus 로고    scopus 로고
    • Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model
    • Sevko, A., Michels, T., Vrohlings, M., Umansky, L., Beckhove, P., Kato, M., Shurin, G.V., Shurin, M.R., Umansky, V., Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model. J. Immunol. 190 (2013), 2464–2471.
    • (2013) J. Immunol. , vol.190 , pp. 2464-2471
    • Sevko, A.1    Michels, T.2    Vrohlings, M.3    Umansky, L.4    Beckhove, P.5    Kato, M.6    Shurin, G.V.7    Shurin, M.R.8    Umansky, V.9
  • 27
    • 84909608106 scopus 로고    scopus 로고
    • Adverse immunoregulatory effects of 5FU and CPT11 chemotherapy on myeloid-derived suppressor cells and colorectal cancer outcomes
    • Kanterman, J., Sade-Feldman, M., Biton, M., Ish-Shalom, E., Lasry, A., Goldshtein, A., Hubert, A., Baniyash, M., Adverse immunoregulatory effects of 5FU and CPT11 chemotherapy on myeloid-derived suppressor cells and colorectal cancer outcomes. Cancer Res. 74 (2014), 6022–6035.
    • (2014) Cancer Res. , vol.74 , pp. 6022-6035
    • Kanterman, J.1    Sade-Feldman, M.2    Biton, M.3    Ish-Shalom, E.4    Lasry, A.5    Goldshtein, A.6    Hubert, A.7    Baniyash, M.8
  • 29
    • 84939526522 scopus 로고    scopus 로고
    • Early cytotoxic lymphocyte expansion contributes to a deep molecular response to dasatinib in patients with newly diagnosed chronic myeloid leukemia in the chronic phase: results of the D-first study
    • Iriyama, N., Fujisawa, S., Yoshida, C., Wakita, H., Chiba, S., Okamoto, S., Kawakami, K., Takezako, N., Kumagai, T., Inokuchi, K., et al. Early cytotoxic lymphocyte expansion contributes to a deep molecular response to dasatinib in patients with newly diagnosed chronic myeloid leukemia in the chronic phase: results of the D-first study. Am. J. Hematol. 90 (2015), 819–824.
    • (2015) Am. J. Hematol. , vol.90 , pp. 819-824
    • Iriyama, N.1    Fujisawa, S.2    Yoshida, C.3    Wakita, H.4    Chiba, S.5    Okamoto, S.6    Kawakami, K.7    Takezako, N.8    Kumagai, T.9    Inokuchi, K.10
  • 31
    • 84899073185 scopus 로고    scopus 로고
    • Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma
    • Lowe, D.B., Bose, A., Taylor, J.L., Tawbi, H., Lin, Y., Kirkwood, J.M., Storkus, W.J., Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma. Oncoimmunology, 3, 2014, e27589.
    • (2014) Oncoimmunology , vol.3 , pp. e27589
    • Lowe, D.B.1    Bose, A.2    Taylor, J.L.3    Tawbi, H.4    Lin, Y.5    Kirkwood, J.M.6    Storkus, W.J.7
  • 32
    • 84995528360 scopus 로고    scopus 로고
    • Restoring lost anti-HER-2 Th1 immunity in breast cancer: a crucial role for Th1 cytokines in therapy and prevention
    • Nocera, N.F., Lee, M.C., La, Cruz LMD, Rosemblit, C., Czerniecki, B.J., Restoring lost anti-HER-2 Th1 immunity in breast cancer: a crucial role for Th1 cytokines in therapy and prevention. Front. Pharmacol. 7 (2016), 1–12.
    • (2016) Front. Pharmacol. , vol.7 , pp. 1-12
    • Nocera, N.F.1    Lee, M.C.2    La, C.L.3    Rosemblit, C.4    Czerniecki, B.J.5
  • 34
    • 84934339796 scopus 로고    scopus 로고
    • Progressive loss of anti-HER2 CD4(+) T-helper type 1 response in breast tumorigenesis and the potential for immune restoration
    • This study shows that impaired Th1 immune response in HER2-driven breast cancer patients can be restored by specific DC vaccination that may improve immune response to neoadjuvant trastuzumab/chemotherapy.
    • Datta, J., Rosemblit, C., Berk, E., Showalter, L., Namjoshi, P., Mick, R., Lee, K.P., Brod, A.M., Yang, R.L., Kelz, R.R., et al. Progressive loss of anti-HER2 CD4(+) T-helper type 1 response in breast tumorigenesis and the potential for immune restoration. Oncoimmunology, 4, 2015, e1022301 This study shows that impaired Th1 immune response in HER2-driven breast cancer patients can be restored by specific DC vaccination that may improve immune response to neoadjuvant trastuzumab/chemotherapy.
    • (2015) Oncoimmunology , vol.4 , pp. e1022301
    • Datta, J.1    Rosemblit, C.2    Berk, E.3    Showalter, L.4    Namjoshi, P.5    Mick, R.6    Lee, K.P.7    Brod, A.M.8    Yang, R.L.9    Kelz, R.R.10
  • 36
    • 84945237892 scopus 로고    scopus 로고
    • Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells
    • Hu, S., Liu, L., Chang, E.B., Wang, J.Y., Raufman, J.P., Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells. Mol. Cancer, 14, 2015, 180.
    • (2015) Mol. Cancer , vol.14 , pp. 180
    • Hu, S.1    Liu, L.2    Chang, E.B.3    Wang, J.Y.4    Raufman, J.P.5
  • 43
    • 84994831796 scopus 로고    scopus 로고
    • Enterococcus hirae and Barnesiella intestinihominis facilitate cyclophosphamide-induced therapeutic immunomodulatory effects
    • This study highlights that the anticancer efficacy of cyclophosphamide requires immune contexture changes that depend on some commensals from the gut microbiota.
    • Daillère, R., Vétizou, M., Waldschmitt, N., Yamazaki, T., Isnard, C., Poirier-Colame, V., Duong, C.P.M., Flament, C., Lepage, P., Roberti, M.P., et al. Enterococcus hirae and Barnesiella intestinihominis facilitate cyclophosphamide-induced therapeutic immunomodulatory effects. Immunity 45 (2016), 931–943 This study highlights that the anticancer efficacy of cyclophosphamide requires immune contexture changes that depend on some commensals from the gut microbiota.
    • (2016) Immunity , vol.45 , pp. 931-943
    • Daillère, R.1    Vétizou, M.2    Waldschmitt, N.3    Yamazaki, T.4    Isnard, C.5    Poirier-Colame, V.6    Duong, C.P.M.7    Flament, C.8    Lepage, P.9    Roberti, M.P.10
  • 44
    • 84920025561 scopus 로고    scopus 로고
    • Insights into the role of the microbiome in obesity and type 2 diabetes
    • Hartstra, A.V., Bouter, K.E.C., Bäckhed, F., Nieuwdorp, M., Insights into the role of the microbiome in obesity and type 2 diabetes. Diabetes Care 38 (2015), 159–165.
    • (2015) Diabetes Care , vol.38 , pp. 159-165
    • Hartstra, A.V.1    Bouter, K.E.C.2    Bäckhed, F.3    Nieuwdorp, M.4
  • 46
    • 84908608590 scopus 로고    scopus 로고
    • The gut microbiota, bacterial metabolites and colorectal cancer
    • Louis, P., Hold, G.L., Flint, H.J., The gut microbiota, bacterial metabolites and colorectal cancer. Nat. Rev. Microbiol. 12 (2014), 661–672.
    • (2014) Nat. Rev. Microbiol. , vol.12 , pp. 661-672
    • Louis, P.1    Hold, G.L.2    Flint, H.J.3
  • 48
    • 68149155982 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
    • Peggs, K.S., Quezada, S.A., Chambers, C.A., Korman, A.J., Allison, J.P., Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J. Exp. Med. 206 (2009), 1717–1725.
    • (2009) J. Exp. Med. , vol.206 , pp. 1717-1725
    • Peggs, K.S.1    Quezada, S.A.2    Chambers, C.A.3    Korman, A.J.4    Allison, J.P.5
  • 50
    • 84956619454 scopus 로고    scopus 로고
    • Acquired resistance to immunotherapy and future challenges
    • Views of three scientists on evidence for the existence of acquired resistance to immunotherapy in patients and discussion of future issues related to immunotherapy.
    • Restifo, N.P., Smyth, M.J., Snyder, A., Acquired resistance to immunotherapy and future challenges. Nat. Rev. Cancer 16 (2016), 121–126 Views of three scientists on evidence for the existence of acquired resistance to immunotherapy in patients and discussion of future issues related to immunotherapy.
    • (2016) Nat. Rev. Cancer , vol.16 , pp. 121-126
    • Restifo, N.P.1    Smyth, M.J.2    Snyder, A.3
  • 51
    • 84937246543 scopus 로고    scopus 로고
    • Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?
    • Apetoh, L., Ladoire, S., Coukos, G., Ghiringhelli, F., Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?. Ann. Oncol. 26 (2015), 1813–1823.
    • (2015) Ann. Oncol. , vol.26 , pp. 1813-1823
    • Apetoh, L.1    Ladoire, S.2    Coukos, G.3    Ghiringhelli, F.4
  • 52
    • 84958124766 scopus 로고    scopus 로고
    • Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy
    • The authors show that chemotherapeutic agents by inducing tumor immunogenicity through the triggering of tumor T cell infiltration can sensitize unresponsive neoplasms to immune checkpoint blockers.
    • Pfirschke, C., Engblom, C., Rickelt, S., Cortez-Retamozo, V., Garris, C., Pucci, F., Yamazaki, T., Poirier-Colame, V., Newton, A., Redouane, Y., et al. Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy. Immunity 44 (2016), 343–354 The authors show that chemotherapeutic agents by inducing tumor immunogenicity through the triggering of tumor T cell infiltration can sensitize unresponsive neoplasms to immune checkpoint blockers.
    • (2016) Immunity , vol.44 , pp. 343-354
    • Pfirschke, C.1    Engblom, C.2    Rickelt, S.3    Cortez-Retamozo, V.4    Garris, C.5    Pucci, F.6    Yamazaki, T.7    Poirier-Colame, V.8    Newton, A.9    Redouane, Y.10
  • 54
    • 85006987606 scopus 로고    scopus 로고
    • Anti – PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM
    • This study reveals that local delivery of chemotherapy can ameliorate the effects of immunotherapy, hence highlighting a novel aspect to consider for the optimization of chemo-immunotherapy combination.
    • Mathios, D., Kim, J.E., Mangraviti, A., Phallen, J., Park, C., Jackson, C.M., Garzon-muvdi, T., Kim, E., Theodros, D., Polanczyk, M., et al. Anti – PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM. Sci. Transl. Med. 8 (2016), 1–12 This study reveals that local delivery of chemotherapy can ameliorate the effects of immunotherapy, hence highlighting a novel aspect to consider for the optimization of chemo-immunotherapy combination.
    • (2016) Sci. Transl. Med. , vol.8 , pp. 1-12
    • Mathios, D.1    Kim, J.E.2    Mangraviti, A.3    Phallen, J.4    Park, C.5    Jackson, C.M.6    Garzon-muvdi, T.7    Kim, E.8    Theodros, D.9    Polanczyk, M.10
  • 55
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: impact on clinical outcome
    • Fridman, W.H., Pagès, F., Sautès-Fridman, C., Galon, J., The immune contexture in human tumours: impact on clinical outcome. Nat. Rev. Cancer 12 (2012), 298–306.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pagès, F.2    Sautès-Fridman, C.3    Galon, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.