The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development

Immunity

Volumn 46, Issue 5, 2017, Pages 818-834.e4

  Miyazaki, Masaki ^a,b   Miyazaki, Kazuko ^a,b   Chen, Kenian ^c   Jin, Yi ^c   Turner, Jacob ^c   Moore, Amanda J ^b   Saito, Rintaro ^d   Yoshida, Kenichi ^e   Ogawa, Seishi ^e   Rodewald, Hans Reimer ^f   Lin, Yin C ^c   Kawamoto, Hiroshi ^a   Murre, Cornelis ^b  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e KYOTO UNIVERSITY   (Japan)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

basic helix loop helix transcription factor; E ID protein axis; E2A; early T cell progenitor; HEB; innate lymphoid cell; Notch signaling; regulome; T cell development

Indexed keywords

NOTCH1 RECEPTOR; PROTEIN; RAG1 PROTEIN; RAG2 PROTEIN; T LYMPHOCYTE RECEPTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; INHIBITOR OF DIFFERENTIATION 2; TCF3 PROTEIN, MOUSE; TRANSCRIPTOME;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL EXPANSION; CELL FATE; CELL MATURATION; CELL POPULATION; ENHANCER REGION; GENE LOCUS; INNATE IMMUNITY; LYMPHOID CELL; LYMPHOID ORGAN; NONHUMAN; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; THYMUS; ADAPTIVE IMMUNITY; ANIMAL; CLUSTER ANALYSIS; CYTOLOGY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; IMMUNOLOGY; IMMUNOMODULATION; IMMUNOPHENOTYPING; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; LYMPHOID PROGENITOR CELL; METABOLISM; MOUSE; PHENOTYPE; THYMOCYTE; TRANSGENIC MOUSE;

ADAPTIVE IMMUNITY; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CLUSTER ANALYSIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; IMMUNITY, INNATE; IMMUNOMODULATION; IMMUNOPHENOTYPING; INHIBITOR OF DIFFERENTIATION PROTEIN 2; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; LYMPHOID PROGENITOR CELLS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE; T-CELL ANTIGEN RECEPTOR SPECIFICITY; THYMOCYTES; TRANSCRIPTOME;

EID: 85019479989     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.04.022     Document Type: Article

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