Critical role of the cAMP-PKA pathway in hyperglycemia-induced epigenetic activation of fibrogenic program in the kidney

FASEB Journal

Volumn 31, Issue 5, 2017, Pages 2065-2075

  Deb, Dilip K ^a   Bao, Riyue ^a   Li, Yan Chun ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

ChIP Seq; Diabetic complication; Histone acetylation; Protein kinase A; Renal fibrosis

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER 1; HISTONE ACETYLTRANSFERASE; RNA POLYMERASE II; SYNAPTOTAGMIN I; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; DIABETIC NEPHROPATHY; ENZYME INHIBITION; EPIGENETIC REPRESSION; FIBROGENESIS; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HISTONE ACETYLATION; HYPERGLYCEMIA; KIDNEY; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; GENETIC EPIGENESIS; GENETICS; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIABETES MELLITUS, EXPERIMENTAL; EPIGENESIS, GENETIC; HYPERGLYCEMIA; KIDNEY; MICE; NF-KAPPA B; NUCLEAR PROTEINS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 85019435260     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201601116R     Document Type: Article

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