-
2
-
-
0642307263
-
The outcome of liver transplantation in patients with hepatocellular carcinoma in the United States between 1988 and 2001: 5-year survival has improved significantly with time
-
Yoo HY, Patt CH, Geschwind JF, Thuluvath PJ. The outcome of liver transplantation in patients with hepatocellular carcinoma in the United States between 1988 and 2001: 5-year survival has improved significantly with time. J Clin Oncol. 2003;21:4329-35.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4329-4335
-
-
Yoo, H.Y.1
Patt, C.H.2
Geschwind, J.F.3
Thuluvath, P.J.4
-
4
-
-
84855805682
-
Tumoral and angiogenesis factors in hepatocellular carcinoma after locoregional therapy
-
Farris III AB, Dursun N, Dhanasekaran R, Coban I, McIntosh EB, Adsay NV. Tumoral and angiogenesis factors in hepatocellular carcinoma after locoregional therapy. Pathol Res Pract. 2012;208:15-21.
-
(2012)
Pathol Res Pract
, vol.208
, pp. 15-21
-
-
Farris, A.B.1
Dursun, N.2
Dhanasekaran, R.3
Coban, I.4
McIntosh, E.B.5
Adsay, N.V.6
-
5
-
-
0037320451
-
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
-
Oshiumi H, Matsumoto M, Funami K, Akazawa T, Seya T. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat Immunol. 2003;4:161-7.
-
(2003)
Nat Immunol
, vol.4
, pp. 161-167
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
6
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science. 2003;301:640-3.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
-
7
-
-
3142724031
-
Toll-like receptor signaling
-
Akira S, Takeda K. Toll-like receptor signaling. Nat Rev Immunol. 2004;4:499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
8
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
O'Neill LA, Bowie AG. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol. 2007;7:353-64.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
9
-
-
2442605662
-
Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways
-
Han KJ, Su X, Xu LG, Bin LH, Zhang J, Shu HB. Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. J Biol Chem. 2004;279:15652-61.
-
(2004)
J Biol Chem
, vol.279
, pp. 15652-15661
-
-
Han, K.J.1
Su, X.2
Xu, L.G.3
Bin, L.H.4
Zhang, J.5
Shu, H.B.6
-
10
-
-
17144413785
-
Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif
-
Kaiser WJ, Offermann MK. Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif. J Immunol. 2005;174:4942-52.
-
(2005)
J Immunol
, vol.174
, pp. 4942-4952
-
-
Kaiser, W.J.1
Offermann, M.K.2
-
11
-
-
4344622049
-
Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages
-
Ruckdeschel K, Pfaffinger G, Haase R, Sing A, Weighardt H, Häcker G, et al. Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages. J Immunol. 2004;173:3320-8.
-
(2004)
J Immunol
, vol.173
, pp. 3320-3328
-
-
Ruckdeschel, K.1
Pfaffinger, G.2
Haase, R.3
Sing, A.4
Weighardt, H.5
Häcker, G.6
-
12
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle S, Vaidya S, O'Connell R, Dadgostar H, Dempsey P, Wu T, et al. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity. 2002;17:251-63.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
-
13
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation
-
Meylan E, Burns K, Hofmann K, Blancheteau V, Martinon F, Kelliher M, et al. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol. 2004;5:503-7.
-
(2004)
Nat Immunol
, vol.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
Kelliher, M.6
-
14
-
-
4344613405
-
Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling
-
Gohda J, Matsumura T, Inoue J. Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling. J Immunol. 2004;173:2913-7.
-
(2004)
J Immunol
, vol.173
, pp. 2913-2917
-
-
Gohda, J.1
Matsumura, T.2
Inoue, J.3
-
15
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling
-
Sato S, Sugiyama M, Yamamoto M, Watanabe Y, Kawai T, Takeda K, et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J Immunol. 2003;171:4304-10.
-
(2003)
J Immunol
, vol.171
, pp. 4304-4310
-
-
Sato, S.1
Sugiyama, M.2
Yamamoto, M.3
Watanabe, Y.4
Kawai, T.5
Takeda, K.6
-
16
-
-
0038714270
-
Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
-
Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X. Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J Biol Chem. 2003;278:16713-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 16713-16719
-
-
Jiang, Z.1
Zamanian-Daryoush, M.2
Nie, H.3
Silva, A.M.4
Williams, B.R.5
Li, X.6
-
17
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, et al. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 2005;19:2668-81.
-
(2005)
Genes Dev
, vol.19
, pp. 2668-2681
-
-
Shim, J.H.1
Xiao, C.2
Paschal, A.E.3
Bailey, S.T.4
Rao, P.5
Hayden, M.S.6
-
18
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007;132:2557-76.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
19
-
-
84904266099
-
The long noncoding RNA expression profile of hepatocellular carcinoma identified by microarray analysis
-
Zhu J, Liu S, Ye F, Shen Y, Tie Y, Zhu J, et al. The long noncoding RNA expression profile of hepatocellular carcinoma identified by microarray analysis. PLoS One. 2014;9:e101707.
-
(2014)
PLoS One
, vol.9
, pp. e101707
-
-
Zhu, J.1
Liu, S.2
Ye, F.3
Shen, Y.4
Tie, Y.5
Zhu, J.6
-
20
-
-
84870915632
-
Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients
-
Chew V, Tow C, Huang C, Bard-Chapeau E, Copeland NG, Jenkins NA, et al. Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients. J Natl Cancer Inst. 2012;104:1796-807.
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 1796-1807
-
-
Chew, V.1
Tow, C.2
Huang, C.3
Bard-Chapeau, E.4
Copeland, N.G.5
Jenkins, N.A.6
-
21
-
-
0041331693
-
Subcellular localization of Toll-like receptor 3 in human dendritic cells
-
Matsumoto M, Funami K, Tanabe M, Oshiumi H, Shingai M, Seto Y, et al. Subcellular localization of Toll-like receptor 3 in human dendritic cells. J Immunol. 2003;171:3154-62.
-
(2003)
J Immunol
, vol.171
, pp. 3154-3162
-
-
Matsumoto, M.1
Funami, K.2
Tanabe, M.3
Oshiumi, H.4
Shingai, M.5
Seto, Y.6
-
22
-
-
10244270620
-
p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells
-
Pisegna S, Pirozzi G, Piccoli M, Frati L, Santoni A, Palmieri G. p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells. Blood. 2004;104:4157-64.
-
(2004)
Blood
, vol.104
, pp. 4157-4164
-
-
Pisegna, S.1
Pirozzi, G.2
Piccoli, M.3
Frati, L.4
Santoni, A.5
Palmieri, G.6
-
23
-
-
77957940944
-
Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis
-
Farina GA, York MR, Di Marzio M, Collins CA, Meller S, Homey B, et al. Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis. J Invest Dermatol. 2010;130:2583-93.
-
(2010)
J Invest Dermatol
, vol.130
, pp. 2583-2593
-
-
Farina, G.A.1
York, M.R.2
Marzio, M.3
Collins, C.A.4
Meller, S.5
Homey, B.6
-
24
-
-
14044267522
-
Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
-
Guillot L, Le Goffic R, Bloch S, Escriou N, Akira S, Chignard M, et al. Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J Biol Chem. 2005;280:5571-80.
-
(2005)
J Biol Chem
, vol.280
, pp. 5571-5580
-
-
Guillot, L.1
Goffic, R.2
Bloch, S.3
Escriou, N.4
Akira, S.5
Chignard, M.6
-
25
-
-
20444442721
-
Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes
-
Li K, Chen Z, Kato N, Gale Jr M, Lemon SM. Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. J Biol Chem. 2005;280:16739-47.
-
(2005)
J Biol Chem
, vol.280
, pp. 16739-16747
-
-
Li, K.1
Chen, Z.2
Kato, N.3
Gale, M.4
Lemon, S.M.5
-
26
-
-
58149195681
-
Dual topology of functional Toll-like receptor 3 expression in human hepatocellular carcinoma: differential signaling mechanisms of TLR3-induced NF-ΚB activation and apoptosis
-
Yoneda K, Sugimoto K, Shiraki K, Tanaka J, Beppu T, Fuke H, et al. Dual topology of functional Toll-like receptor 3 expression in human hepatocellular carcinoma: differential signaling mechanisms of TLR3-induced NF-ΚB activation and apoptosis. Int J Oncol. 2008;33:929-36.
-
(2008)
Int J Oncol
, vol.33
, pp. 929-936
-
-
Yoneda, K.1
Sugimoto, K.2
Shiraki, K.3
Tanaka, J.4
Beppu, T.5
Fuke, H.6
-
27
-
-
0034025957
-
The IRF-3 transcription factor mediates Sendai virus-induced apoptosis
-
Heylbroeck C, Balachandran S, Servant MJ, DeLuca C, Barber GN, Lin R, et al. The IRF-3 transcription factor mediates Sendai virus-induced apoptosis. J Virol. 2000;74:3781-92.
-
(2000)
J Virol
, vol.74
, pp. 3781-3792
-
-
Heylbroeck, C.1
Balachandran, S.2
Servant, M.J.3
DeLuca, C.4
Barber, G.N.5
Lin, R.6
-
28
-
-
67651160923
-
Toll-like receptor 3 signaling attenuates liver regeneration
-
Zorde-Khvalevsky E, Abramovitch R, Barash H, Spivak-Pohis I, Rivkin L, Rachmilewitz J, et al. Toll-like receptor 3 signaling attenuates liver regeneration. Hepatology. 2009;50:198-206.
-
(2009)
Hepatology
, vol.50
, pp. 198-206
-
-
Zorde-Khvalevsky, E.1
Abramovitch, R.2
Barash, H.3
Spivak-Pohis, I.4
Rivkin, L.5
Rachmilewitz, J.6
-
29
-
-
2342564453
-
Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand/Fas interaction
-
Heath RM, Jayne DG, O'Leary R, Morrison EE, Guillou PJ. Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand/Fas interaction. Br J Cancer. 2004;90:1437-42.
-
(2004)
Br J Cancer
, vol.90
, pp. 1437-1442
-
-
Heath, R.M.1
Jayne, D.G.2
O'Leary, R.3
Morrison, E.E.4
Guillou, P.J.5
-
30
-
-
34347263727
-
Role of Bcl-2 family members on apoptosis: what we have learned from knock-out mice
-
Roset R, Ortet L, Gil-Gomez G. Role of Bcl-2 family members on apoptosis: what we have learned from knock-out mice. Front Biosci. 2007;12:4722-30.
-
(2007)
Front Biosci
, vol.12
, pp. 4722-4730
-
-
Roset, R.1
Ortet, L.2
Gil-Gomez, G.3
-
31
-
-
0035969963
-
An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7
-
Shin S, Sung BJ, Cho YS, Kim HJ, Ha NC, Hwang JI, et al. An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7. Biochemistry. 2001;13:1117-23.
-
(2001)
Biochemistry
, vol.13
, pp. 1117-1123
-
-
Shin, S.1
Sung, B.J.2
Cho, Y.S.3
Kim, H.J.4
Ha, N.C.5
Hwang, J.I.6
-
32
-
-
0033017328
-
Caspase inhibitors in prevention of apoptosis
-
Rudel T. Caspase inhibitors in prevention of apoptosis. Herz. 1999;24:236-41.
-
(1999)
Herz
, vol.24
, pp. 236-241
-
-
Rudel, T.1
-
33
-
-
51049100571
-
Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8
-
Maelfait J, Vercammen E, Janssens S, Schotte P, Haegman M, Magez S, et al. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J Exp Med. 2008;205:1967-73.
-
(2008)
J Exp Med
, vol.205
, pp. 1967-1973
-
-
Maelfait, J.1
Vercammen, E.2
Janssens, S.3
Schotte, P.4
Haegman, M.5
Magez, S.6
-
34
-
-
0030955880
-
Nonparenchymal cells from regenerating rat liver generate interleukin-1alpha and -1beta: a mechanism of negative regulation of hepatocyte proliferation
-
Boulton R, Woodman A, Calnan D, Selden C, Tam F, Hodgson H. Nonparenchymal cells from regenerating rat liver generate interleukin-1alpha and -1beta: a mechanism of negative regulation of hepatocyte proliferation. Hepatology. 1997;26:49-58.
-
(1997)
Hepatology
, vol.26
, pp. 49-58
-
-
Boulton, R.1
Woodman, A.2
Calnan, D.3
Selden, C.4
Tam, F.5
Hodgson, H.6
-
35
-
-
84872240151
-
Matrix metalloproteinase-2 as a target for head and neck cancer therapy
-
Chien MH, Lin CW, Cheng CW, Wen YC, Yang SF. Matrix metalloproteinase-2 as a target for head and neck cancer therapy. Expert Opin Ther Targets. 2013;17:203-16.
-
(2013)
Expert Opin Ther Targets
, vol.17
, pp. 203-216
-
-
Chien, M.H.1
Lin, C.W.2
Cheng, C.W.3
Wen, Y.C.4
Yang, S.F.5
-
36
-
-
0037065852
-
Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration
-
Iwaguro H, Yamaguchi J, Kalka C, Murasawa S, Masuda H, Hayashi S, et al. Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. Circulation. 2002;105:732-8.
-
(2002)
Circulation
, vol.105
, pp. 732-738
-
-
Iwaguro, H.1
Yamaguchi, J.2
Kalka, C.3
Murasawa, S.4
Masuda, H.5
Hayashi, S.6
-
37
-
-
34047266512
-
Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing
-
Matsumoto T, Kawamoto A, Kuroda R, Ishikawa M, Mifune Y, Iwasaki H, et al. Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing. Am J Pathol. 2006;169:1440-57.
-
(2006)
Am J Pathol
, vol.169
, pp. 1440-1457
-
-
Matsumoto, T.1
Kawamoto, A.2
Kuroda, R.3
Ishikawa, M.4
Mifune, Y.5
Iwasaki, H.6
-
38
-
-
33750991077
-
CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cells
-
Kawamoto A, Iwasaki H, Kusano K, Murayama T, Oyamada A, Silver M, et al. CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cells. Circulation. 2006;114:2163-9.
-
(2006)
Circulation
, vol.114
, pp. 2163-2169
-
-
Kawamoto, A.1
Iwasaki, H.2
Kusano, K.3
Murayama, T.4
Oyamada, A.5
Silver, M.6
-
39
-
-
81855194057
-
The functional expression of TLR3 in EPCs impairs cell proliferation by induction of cell apoptosis and cell cycle progress inhibition
-
Yang M, Xiao Z, Lv Q, Liu X, Zhou L, Chen X, et al. The functional expression of TLR3 in EPCs impairs cell proliferation by induction of cell apoptosis and cell cycle progress inhibition. Int Immunopharmacol. 2011;11:2118-24.
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 2118-2124
-
-
Yang, M.1
Xiao, Z.2
Lv, Q.3
Liu, X.4
Zhou, L.5
Chen, X.6
-
40
-
-
84862912428
-
Double-stranded RNA-induced TLR3 activation inhibits angiogenesis and triggers apoptosis of human hepatocellular carcinoma cells
-
Guo Z, Chen L, Zhu Y, Zhang Y, He S, Qin J, et al. Double-stranded RNA-induced TLR3 activation inhibits angiogenesis and triggers apoptosis of human hepatocellular carcinoma cells. Oncol Rep. 2012;27:396-402.
-
(2012)
Oncol Rep
, vol.27
, pp. 396-402
-
-
Guo, Z.1
Chen, L.2
Zhu, Y.3
Zhang, Y.4
He, S.5
Qin, J.6
-
41
-
-
80053088189
-
Hepatocellular carcinoma
-
El-Serag HB. Hepatocellular carcinoma. N Engl J Med. 2011;365:1118-27.
-
(2011)
N Engl J Med
, vol.365
, pp. 1118-1127
-
-
El-Serag, H.B.1
-
42
-
-
84867147874
-
Prognosis of patients with hepatocellular carcinoma. Validation and ranking of established staging-systems in a large western HCC-cohort
-
Op den Winkel M, Nagel D, Sappl J, op den Winkel P, Lamerz R, Zech CJ, et al. Prognosis of patients with hepatocellular carcinoma. Validation and ranking of established staging-systems in a large western HCC-cohort. PLoS One. 2012;7:e45066.
-
(2012)
PLoS One
, vol.7
, pp. e45066
-
-
Winkel, M.1
Nagel, D.2
Sappl, J.3
Winkel, P.4
Lamerz, R.5
Zech, C.J.6
|