Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection

Journal of Neuroimmunology

Volumn 308, Issue , 2017, Pages 118-130

  Cain, Matthew D ^a   Salimi, Hamid ^a   Gong, Yongfeng ^a   Yang, Lihua ^a   Hamilton, Samantha L ^a   Heffernan, James R ^a   Hou, Jianghui ^a   Miller, Mark J ^a   Klein, Robyn S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CX3CR1; CLAUDIN 5; INTERFERON; TETRATRICOPEPTIDE REPEAT PROTEIN; ADAPTOR PROTEIN; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

5' UNTRANSLATED REGION; ALPHAVIRUS INFECTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CELL INFILTRATION; CELL INTERACTION; CELL JUNCTION; CONTROLLED STUDY; ENDOTHELIUM CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMBRANE PERMEABILITY; MONONUCLEAR CELL; MOUSE; MULTIPHOTON MICROSCOPY; NERVE FIBER TRANSPORT; NEUROEPITHELIUM; NONHUMAN; NOSE INFECTION; OLFACTORY BULB; OLFACTORY CORTEX; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RHOMBENCEPHALON; RNA TRANSLATION; TIGHT JUNCTION; VENEZUELAN EQUINE ENCEPHALITIS; VIRAL CLEARANCE; VIRUS ENTRY; VIRUS EXPRESSION; VIRUS REPLICATION; VIRUS TRANSCRIPTION; ANIMAL; BRAIN; BRAIN CORTEX; C57BL MOUSE; CAPILLARY PERMEABILITY; CELL CULTURE; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; METABOLISM; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; ULTRASTRUCTURE; VENEZUELAN EQUINE ENCEPHALITIS VIRUS; VIROLOGY;

ADAPTOR PROTEIN COMPLEX 1; ALPHAVIRUS INFECTIONS; ANIMALS; ANIMALS, NEWBORN; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARY PERMEABILITY; CELLS, CULTURED; CEREBRAL CORTEX; CRICETINAE; DISEASE MODELS, ANIMAL; ENCEPHALITIS VIRUS, VENEZUELAN EQUINE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, CHEMOKINE; TUMOR NECROSIS FACTOR-ALPHA; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 85019114297     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2017.04.008     Document Type: Article

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