Tumour necrosis factor-α-mediated disruption of cerebrovascular endothelial barrier integrity in vitro involves the production of proinflammatory interleukin-6

Journal of Neurochemistry

Volumn 136, Issue 3, 2016, Pages 564-572

  Rochfort, Keith D ^a   Collins, Laura E ^a   McLoughlin, Alisha ^a   Cummins, Philip M ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

blood brain barrier; endothelial; IL 6; reactive oxygen species; TNF

Indexed keywords

INTERLEUKIN 6; NEUTRALIZING ANTIBODY; TIGHT JUNCTION PROTEIN; TUMOR NECROSIS FACTOR ALPHA; ANTIBODY; CADHERIN; CLAUDIN 5; LEUKOCYTE ANTIGEN; MESSENGER RNA; PROTEIN ZO1; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TJP1 PROTEIN, HUMAN; VASCULAR ENDOTHELIAL CADHERIN;

ARTICLE; BLOOD BRAIN BARRIER; CAPILLARY ENDOTHELIAL CELL; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANALYSIS OF VARIANCE; CAPILLARY PERMEABILITY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; METABOLISM; TIME FACTOR;

ANALYSIS OF VARIANCE; ANTIBODIES; ANTIGENS, CD; CADHERINS; CAPILLARY PERMEABILITY; CLAUDIN-5; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84955291052     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13408     Document Type: Article

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