메뉴 건너뛰기




Volumn 44, Issue , 2017, Pages 15-25

Genetics of gonadotropins and their receptors as markers of ovarian reserve and response in controlled ovarian stimulation

Author keywords

ART; FSH; gonadotropins; hCG; LH; ovarian reserve

Indexed keywords

CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; FOLLITROPIN; FOLLITROPIN BETA SUBUNIT; FOLLITROPIN RECEPTOR; GONADOTROPIN; GONADOTROPIN RECEPTOR; LUTEINIZING HORMONE; LUTEINIZING HORMONE BETA SUBUNIT; LUTEINIZING HORMONE RECEPTOR;

EID: 85019113453     PISSN: 15216934     EISSN: 15321932     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2017.04.002     Document Type: Review
Times cited : (29)

References (94)
  • 1
    • 26444456665 scopus 로고    scopus 로고
    • Regulation of primordial follicle assembly and development
    • Skinner, M.K., Regulation of primordial follicle assembly and development. Hum Reprod Update 11 (2005), 461–471, 10.1093/humupd/dmi020.
    • (2005) Hum Reprod Update , vol.11 , pp. 461-471
    • Skinner, M.K.1
  • 2
    • 84975079543 scopus 로고    scopus 로고
    • Poor ovarian reserve
    • Jirge, P.R., Poor ovarian reserve. J Hum Reprod Sci 9 (2016), 63–69, 10.4103/0974-1208.183514.
    • (2016) J Hum Reprod Sci , vol.9 , pp. 63-69
    • Jirge, P.R.1
  • 3
    • 0036217072 scopus 로고    scopus 로고
    • The lutropin/choriogonadotropin receptor, a 2002 perspective
    • Ascoli, M., Fanelli, F., Segaloff, D.L., The lutropin/choriogonadotropin receptor, a 2002 perspective. Endocr Rev 23 (2002), 141–174, 10.1210/edrv.23.2.0462.
    • (2002) Endocr Rev , vol.23 , pp. 141-174
    • Ascoli, M.1    Fanelli, F.2    Segaloff, D.L.3
  • 4
    • 0031457992 scopus 로고    scopus 로고
    • The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology
    • Simoni, M., Gromoll, J., Nieschlag, E., The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology. Endocr Rev 18 (1997), 739–773, 10.1210/edrv.18.6.0320.
    • (1997) Endocr Rev , vol.18 , pp. 739-773
    • Simoni, M.1    Gromoll, J.2    Nieschlag, E.3
  • 5
    • 84903777220 scopus 로고    scopus 로고
    • FSHR polymorphism p.N680S mediates different responses to FSH in vitro
    • Casarini, L., Moriondo, V., Marino, M., et al. FSHR polymorphism p.N680S mediates different responses to FSH in vitro. Mol Cell Endocrinol 393 (2014), 83–91, 10.1016/j.mce.2014.06.013.
    • (2014) Mol Cell Endocrinol , vol.393 , pp. 83-91
    • Casarini, L.1    Moriondo, V.2    Marino, M.3
  • 6
    • 84957811723 scopus 로고    scopus 로고
    • Impact of gene polymorphisms of gonadotropins and their receptors on human reproductive success
    • Casarini, L., Santi, D., Marino, M., Impact of gene polymorphisms of gonadotropins and their receptors on human reproductive success. Reproduction 150 (2015), R175–R184, 10.1530/REP-15-0251.
    • (2015) Reproduction , vol.150 , pp. R175-R184
    • Casarini, L.1    Santi, D.2    Marino, M.3
  • 7
    • 0033763139 scopus 로고    scopus 로고
    • Day 3 serum inhibin B and FSH and age as predictors of assisted reproduction treatment outcome
    • Creus, M., Peñarrubia, J., Fábregues, F., et al. Day 3 serum inhibin B and FSH and age as predictors of assisted reproduction treatment outcome. Hum Reprod 15 (2000), 2341–2346.
    • (2000) Hum Reprod , vol.15 , pp. 2341-2346
    • Creus, M.1    Peñarrubia, J.2    Fábregues, F.3
  • 8
    • 84876415201 scopus 로고    scopus 로고
    • Polymorphisms in gonadotropin and gonadotropin receptor genes as markers of ovarian reserve and response in in vitro fertilization
    • 970–8.e1
    • La Marca, A., Sighinolfi, G., Argento, C., et al. Polymorphisms in gonadotropin and gonadotropin receptor genes as markers of ovarian reserve and response in in vitro fertilization. Fertil Steril, 99, 2013, 10.1016/j.fertnstert.2013.01.086 970–8.e1.
    • (2013) Fertil Steril , vol.99
    • La Marca, A.1    Sighinolfi, G.2    Argento, C.3
  • 9
    • 84889686581 scopus 로고    scopus 로고
    • Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice
    • La Marca, A., Sunkara, S.K., Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice. Hum Reprod Update 20 (2014), 124–140, 10.1093/humupd/dmt037.
    • (2014) Hum Reprod Update , vol.20 , pp. 124-140
    • La Marca, A.1    Sunkara, S.K.2
  • 10
    • 85015487058 scopus 로고    scopus 로고
    • Comparison of different stimulation protocols used in in vitro fertilization: a review
    • Shrestha, D., La, X., Feng, H.L., Comparison of different stimulation protocols used in in vitro fertilization: a review. Ann Transl Med, 3, 2015, 137, 10.3978/j.issn.2305-5839.2015.04.09.
    • (2015) Ann Transl Med , vol.3 , pp. 137
    • Shrestha, D.1    La, X.2    Feng, H.L.3
  • 11
    • 23744489576 scopus 로고    scopus 로고
    • Comparison of a gonadotropin-releasing hormone (GnRH) antagonist and GnRH agonist flare-up regimen in poor responders undergoing ovarian stimulation
    • Malmusi, S., La Marca, A., Giulini, S., et al. Comparison of a gonadotropin-releasing hormone (GnRH) antagonist and GnRH agonist flare-up regimen in poor responders undergoing ovarian stimulation. Fertil Steril 84 (2005), 402–406, 10.1016/j.fertnstert.2005.01.139.
    • (2005) Fertil Steril , vol.84 , pp. 402-406
    • Malmusi, S.1    La Marca, A.2    Giulini, S.3
  • 12
    • 84929055239 scopus 로고    scopus 로고
    • Management of poor responders in IVF: is there anything new?
    • Ubaldi, F., Vaiarelli, A., D'Anna, R., et al. Management of poor responders in IVF: is there anything new?. Biomed Res Int, 2014, 2014, 352098, 10.1155/2014/352098.
    • (2014) Biomed Res Int , vol.2014 , pp. 352098
    • Ubaldi, F.1    Vaiarelli, A.2    D'Anna, R.3
  • 13
    • 85013782523 scopus 로고    scopus 로고
    • Poor responders in in vitro fertilization (IVF) therapy: the challenge continues
    • Oehninger, S., Poor responders in in vitro fertilization (IVF) therapy: the challenge continues. Facts Views Vis Obgyn 3 (2011), 101–108.
    • (2011) Facts Views Vis Obgyn , vol.3 , pp. 101-108
    • Oehninger, S.1
  • 14
    • 84895075036 scopus 로고    scopus 로고
    • Ovarian response markers lead to appropriate and effective use of corifollitropin alpha in assisted reproduction
    • La Marca, A., D'Ippolito, G., Ovarian response markers lead to appropriate and effective use of corifollitropin alpha in assisted reproduction. Reprod Biomed Online 28 (2014), 183–190, 10.1016/j.rbmo.2013.10.012.
    • (2014) Reprod Biomed Online , vol.28 , pp. 183-190
    • La Marca, A.1    D'Ippolito, G.2
  • 15
    • 84976519921 scopus 로고    scopus 로고
    • Introduction: determinants of polycystic ovary syndrome
    • Azziz, R., Introduction: determinants of polycystic ovary syndrome. Fertil Steril 106 (2016), 4–5, 10.1016/j.fertnstert.2016.05.009.
    • (2016) Fertil Steril , vol.106 , pp. 4-5
    • Azziz, R.1
  • 16
    • 84855646730 scopus 로고    scopus 로고
    • Effects of polymorphisms in gonadotropin and gonadotropin receptor genes on reproductive function
    • Casarini, L., Pignatti, E., Simoni, M., Effects of polymorphisms in gonadotropin and gonadotropin receptor genes on reproductive function. Rev Endocr Metab Disord 12 (2011), 303–321, 10.1007/s11154-011-9192-2.
    • (2011) Rev Endocr Metab Disord , vol.12 , pp. 303-321
    • Casarini, L.1    Pignatti, E.2    Simoni, M.3
  • 17
    • 84906315016 scopus 로고    scopus 로고
    • Genetic associations with diminished ovarian reserve: a systematic review of the literature
    • Greene, A.D., Patounakis, G., Segars, J.H., Genetic associations with diminished ovarian reserve: a systematic review of the literature. J Assist Reprod Genet 31 (2014), 935–946, 10.1007/s10815-014-0257-5.
    • (2014) J Assist Reprod Genet , vol.31 , pp. 935-946
    • Greene, A.D.1    Patounakis, G.2    Segars, J.H.3
  • 18
    • 0023735072 scopus 로고
    • Human follicle-stimulating hormone beta-subunit gene encodes multiple messenger ribonucleic acids
    • Jameson, J.L., Becker, C.B., Lindell, C.M., et al. Human follicle-stimulating hormone beta-subunit gene encodes multiple messenger ribonucleic acids. Mol Endocrinol 2 (1988), 806–815, 10.1210/mend-2-9-806.
    • (1988) Mol Endocrinol , vol.2 , pp. 806-815
    • Jameson, J.L.1    Becker, C.B.2    Lindell, C.M.3
  • 19
    • 77957166466 scopus 로고    scopus 로고
    • Genomics and genetics of gonadotropin beta-subunit genes: unique FSHB and duplicated LHB/CGB loci
    • Nagirnaja, L., Rull, K., Uusküla, L., et al. Genomics and genetics of gonadotropin beta-subunit genes: unique FSHB and duplicated LHB/CGB loci. Mol Cell Endocrinol 329 (2010), 4–16, 10.1016/j.mce.2010.04.024.
    • (2010) Mol Cell Endocrinol , vol.329 , pp. 4-16
    • Nagirnaja, L.1    Rull, K.2    Uusküla, L.3
  • 20
    • 84896257707 scopus 로고    scopus 로고
    • Mechanisms in endocrinology: genetics of FSH action: a 2014-and-beyond view
    • Simoni, M., Casarini, L., Mechanisms in endocrinology: genetics of FSH action: a 2014-and-beyond view. Eur J Endocrinol 170 (2014), R91–R107, 10.1530/EJE-13-0624.
    • (2014) Eur J Endocrinol , vol.170 , pp. R91-R107
    • Simoni, M.1    Casarini, L.2
  • 21
    • 54149105985 scopus 로고    scopus 로고
    • FSHB promoter polymorphism within evolutionary conserved element is associated with serum FSH level in men
    • Grigorova, M., Punab, M., Ausmees, K., et al. FSHB promoter polymorphism within evolutionary conserved element is associated with serum FSH level in men. Hum Reprod 23 (2008), 2160–2166, 10.1093/humrep/den216.
    • (2008) Hum Reprod , vol.23 , pp. 2160-2166
    • Grigorova, M.1    Punab, M.2    Ausmees, K.3
  • 22
    • 75149119672 scopus 로고    scopus 로고
    • Increased prevalance of the −211 T allele of follicle stimulating hormone (FSH) β subunit promoter polymorphism and lower serum FSH in infertile men
    • Grigorova, M., Punab, M., Poolamets, O., et al. Increased prevalance of the −211 T allele of follicle stimulating hormone (FSH) β subunit promoter polymorphism and lower serum FSH in infertile men. J Clin Endocrinol Metab 95 (2010), 100–108, 10.1210/jc.2009-1010.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 100-108
    • Grigorova, M.1    Punab, M.2    Poolamets, O.3
  • 23
    • 82455209032 scopus 로고    scopus 로고
    • Toward a pharmacogenetic approach to male infertility: polymorphism of follicle-stimulating hormone beta-subunit promoter
    • 1344–1349.e2
    • Ferlin, A., Vinanzi, C., Selice, R., et al. Toward a pharmacogenetic approach to male infertility: polymorphism of follicle-stimulating hormone beta-subunit promoter. Fertil Steril, 96, 2011, 10.1016/j.fertnstert.2011.09.034 1344–1349.e2.
    • (2011) Fertil Steril , vol.96
    • Ferlin, A.1    Vinanzi, C.2    Selice, R.3
  • 24
    • 80052521669 scopus 로고    scopus 로고
    • Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters
    • Grigorova, M., Punab, M., Zilaitienė, B., et al. Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters. J Clin Endocrinol Metab 96 (2011), E1534–E1541, 10.1210/jc.2011-0632.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. E1534-E1541
    • Grigorova, M.1    Punab, M.2    Zilaitienė, B.3
  • 25
    • 84872067557 scopus 로고    scopus 로고
    • Effects of the FSH-β-subunit promoter polymorphism -211G->T on the hypothalamic-pituitary-ovarian axis in normally cycling women indicate a gender-specific regulation of gonadotropin secretion
    • Schüring, A.N., Busch, A.S., Bogdanova, N., et al. Effects of the FSH-β-subunit promoter polymorphism -211G->T on the hypothalamic-pituitary-ovarian axis in normally cycling women indicate a gender-specific regulation of gonadotropin secretion. J Clin Endocrinol Metab 98 (2013), E82–E86, 10.1210/jc.2012-2780.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. E82-E86
    • Schüring, A.N.1    Busch, A.S.2    Bogdanova, N.3
  • 26
    • 84959880080 scopus 로고    scopus 로고
    • Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health
    • Ruth, K.S., Beaumont, R.N., Tyrrell, J., et al. Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health. Hum Reprod 31 (2016), 473–481, 10.1093/humrep/dev318.
    • (2016) Hum Reprod , vol.31 , pp. 473-481
    • Ruth, K.S.1    Beaumont, R.N.2    Tyrrell, J.3
  • 27
    • 84876584430 scopus 로고    scopus 로고
    • The combination of genetic variants of the FSHB and FSHR genes affects serum FSH in women of reproductive age
    • La Marca, A., Papaleo, E., Alviggi, C., et al. The combination of genetic variants of the FSHB and FSHR genes affects serum FSH in women of reproductive age. Hum Reprod 28 (2013), 1369–1374, 10.1093/humrep/det061.
    • (2013) Hum Reprod , vol.28 , pp. 1369-1374
    • La Marca, A.1    Papaleo, E.2    Alviggi, C.3
  • 28
    • 84886778150 scopus 로고    scopus 로고
    • Mutations and polymorphisms in FSH receptor: functional implications in human reproduction
    • Desai, S.S., Roy, B.S., Mahale, S.D., Mutations and polymorphisms in FSH receptor: functional implications in human reproduction. Reproduction 146 (2013), R235–R248, 10.1530/REP-13-0351.
    • (2013) Reproduction , vol.146 , pp. R235-R248
    • Desai, S.S.1    Roy, B.S.2    Mahale, S.D.3
  • 29
    • 0036298619 scopus 로고    scopus 로고
    • Effects of follicle-stimulating hormone (FSH) and human chorionic gonadotropin in individuals with an inactivating mutation of the FSH receptor
    • Vaskivuo, T.E., Aittomäki, K., Anttonen, M., et al. Effects of follicle-stimulating hormone (FSH) and human chorionic gonadotropin in individuals with an inactivating mutation of the FSH receptor. Fertil Steril 78 (2002), 108–113, 10.1016/S0015-0282(02)03148-5.
    • (2002) Fertil Steril , vol.78 , pp. 108-113
    • Vaskivuo, T.E.1    Aittomäki, K.2    Anttonen, M.3
  • 30
    • 84947488691 scopus 로고    scopus 로고
    • Impact of follicle-stimulating hormone receptor variants in female infertility
    • Ilgaz, N.S., Aydos, O.S.E., Karadag, A., et al. Impact of follicle-stimulating hormone receptor variants in female infertility. J Assist Reprod Genet 32 (2015), 1659–1668, 10.1007/s10815-015-0572-5.
    • (2015) J Assist Reprod Genet , vol.32 , pp. 1659-1668
    • Ilgaz, N.S.1    Aydos, O.S.E.2    Karadag, A.3
  • 31
    • 84902164481 scopus 로고    scopus 로고
    • Constitutive activity in gonadotropin receptors
    • Ulloa-Aguirre, A., Reiter, E., Bousfield, G., et al. Constitutive activity in gonadotropin receptors. Adv Pharmacol 70 (2014), 37–80, 10.1016/B978-0-12-417197-8.00002-X.
    • (2014) Adv Pharmacol , vol.70 , pp. 37-80
    • Ulloa-Aguirre, A.1    Reiter, E.2    Bousfield, G.3
  • 32
    • 0030596101 scopus 로고    scopus 로고
    • Functional and clinical consequences of mutations in the FSH receptor
    • Gromoll, J., Simoni, M., Nordhoff, V., et al. Functional and clinical consequences of mutations in the FSH receptor. Mol Cell Endocrinol 125 (1996), 177–182.
    • (1996) Mol Cell Endocrinol , vol.125 , pp. 177-182
    • Gromoll, J.1    Simoni, M.2    Nordhoff, V.3
  • 33
    • 0029913238 scopus 로고    scopus 로고
    • An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man
    • Gromoll, J., Simoni, M., Nieschlag, E., An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man. J Clin Endocrinol Metab 81 (1996), 1367–1370.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1367-1370
    • Gromoll, J.1    Simoni, M.2    Nieschlag, E.3
  • 34
    • 0033678139 scopus 로고    scopus 로고
    • Ovarian response to follicle-stimulating hormone (FSH) stimulation depends on the FSH receptor genotype
    • Perez Mayorga, M., Gromoll, J., Behre, H.M., et al. Ovarian response to follicle-stimulating hormone (FSH) stimulation depends on the FSH receptor genotype. J Clin Endocrinol Metab 85 (2000), 3365–3369, 10.1210/jcem.85.9.6789.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3365-3369
    • Perez Mayorga, M.1    Gromoll, J.2    Behre, H.M.3
  • 35
    • 65249147155 scopus 로고    scopus 로고
    • Poor ovarian response to gonadotrophin stimulation is associated with FSH receptor polymorphism
    • Achrekar, S., Modi, D., Desai, S., et al. Poor ovarian response to gonadotrophin stimulation is associated with FSH receptor polymorphism. Reprod Biomed Online 18 (2009), 509–515, 10.1016/S1472-6483(10)60127-7.
    • (2009) Reprod Biomed Online , vol.18 , pp. 509-515
    • Achrekar, S.1    Modi, D.2    Desai, S.3
  • 36
    • 84857787794 scopus 로고    scopus 로고
    • Follicle-stimulating hormone receptor gene polymorphisms are not associated with ovarian reserve markers
    • Mohiyiddeen, L., Newman, W.G., McBurney, H., et al. Follicle-stimulating hormone receptor gene polymorphisms are not associated with ovarian reserve markers. Fertil Steril 97 (2012), 677–681, 10.1016/j.fertnstert.2011.12.040.
    • (2012) Fertil Steril , vol.97 , pp. 677-681
    • Mohiyiddeen, L.1    Newman, W.G.2    McBurney, H.3
  • 37
    • 22544475352 scopus 로고    scopus 로고
    • Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation
    • Behre, H.M., Greb, R.R., Mempel, A., et al. Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation. Pharmacogenet Genomics 15 (2005), 451–456.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 451-456
    • Behre, H.M.1    Greb, R.R.2    Mempel, A.3
  • 38
    • 84924049245 scopus 로고    scopus 로고
    • The Ser680Asn polymorphism in the follicle-stimulating hormone receptor gene is associated with the ovarian response in controlled ovarian hyperstimulation
    • Huang, X., Li, L., Hong, L., et al. The Ser680Asn polymorphism in the follicle-stimulating hormone receptor gene is associated with the ovarian response in controlled ovarian hyperstimulation. Clin Endocrinol (Oxf) 82 (2015), 577–583, 10.1111/cen.12573.
    • (2015) Clin Endocrinol (Oxf) , vol.82 , pp. 577-583
    • Huang, X.1    Li, L.2    Hong, L.3
  • 39
    • 55749090118 scopus 로고    scopus 로고
    • Follicle-stimulating hormone receptor and DAZL gene polymorphisms do not affect the age of menopause
    • Zerbetto, I., Gromoll, J., Luisi, S., et al. Follicle-stimulating hormone receptor and DAZL gene polymorphisms do not affect the age of menopause. Fertil Steril 90 (2008), 2264–2268, 10.1016/j.fertnstert.2007.10.036.
    • (2008) Fertil Steril , vol.90 , pp. 2264-2268
    • Zerbetto, I.1    Gromoll, J.2    Luisi, S.3
  • 40
    • 0030063155 scopus 로고    scopus 로고
    • An elevated day three follicle-stimulating hormone: luteinizing hormone ratio (FSH: LH) in the presence of a normal day 3 FSH predicts a poor response to controlled ovarian hyperstimulation
    • Mukherjee, T., Copperman, A.B., Lapinski, R., et al. An elevated day three follicle-stimulating hormone: luteinizing hormone ratio (FSH: LH) in the presence of a normal day 3 FSH predicts a poor response to controlled ovarian hyperstimulation. Fertil Steril 65 (1996), 588–593.
    • (1996) Fertil Steril , vol.65 , pp. 588-593
    • Mukherjee, T.1    Copperman, A.B.2    Lapinski, R.3
  • 41
    • 10344241479 scopus 로고    scopus 로고
    • Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism
    • Daelemans, C., Smits, G., de Maertelaer, V., et al. Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism. J Clin Endocrinol Metab 89 (2004), 6310–6315, 10.1210/jc.2004-1044.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6310-6315
    • Daelemans, C.1    Smits, G.2    de Maertelaer, V.3
  • 42
    • 84862175839 scopus 로고    scopus 로고
    • Genetic polymorphisms influence the ovarian response to rFSH stimulation in patients undergoing in vitro fertilization programs with ICSI
    • Boudjenah, R., Molina-Gomes, D., Torre, A., et al. Genetic polymorphisms influence the ovarian response to rFSH stimulation in patients undergoing in vitro fertilization programs with ICSI. PLoS One, 7, 2012, e38700, 10.1371/journal.pone.0038700.
    • (2012) PLoS One , vol.7 , pp. e38700
    • Boudjenah, R.1    Molina-Gomes, D.2    Torre, A.3
  • 43
    • 84930810440 scopus 로고    scopus 로고
    • Follicle-stimulating hormone receptor polymorphism affects the outcome of ovulation induction in normogonadotropic (World Health Organization class 2) anovulatory subfertility
    • 1081–1088.e3
    • Valkenburg, O., van Santbrink, E.J.P., König, T.E., et al. Follicle-stimulating hormone receptor polymorphism affects the outcome of ovulation induction in normogonadotropic (World Health Organization class 2) anovulatory subfertility. Fertil Steril, 103, 2015, 10.1016/j.fertnstert.2015.01.002 1081–1088.e3.
    • (2015) Fertil Steril , vol.103
    • Valkenburg, O.1    van Santbrink, E.J.P.2    König, T.E.3
  • 44
    • 20544466487 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in the promoter region influence the expression of the human follicle-stimulating hormone receptor
    • Wunsch, A., Ahda, Y., Banaz-Yaşar, F., et al. Single-nucleotide polymorphisms in the promoter region influence the expression of the human follicle-stimulating hormone receptor. Fertil Steril 84 (2005), 446–453, 10.1016/j.fertnstert.2005.02.031.
    • (2005) Fertil Steril , vol.84 , pp. 446-453
    • Wunsch, A.1    Ahda, Y.2    Banaz-Yaşar, F.3
  • 45
    • 80052524413 scopus 로고    scopus 로고
    • Follicle-stimulating hormone receptor polymorphism (G-29A) is associated with altered level of receptor expression in Granulosa cells
    • Desai, S.S., Achrekar, S.K., Pathak, B.R., et al. Follicle-stimulating hormone receptor polymorphism (G-29A) is associated with altered level of receptor expression in Granulosa cells. J Clin Endocrinol Metab 96 (2011), 2805–2812, 10.1210/jc.2011-1064.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 2805-2812
    • Desai, S.S.1    Achrekar, S.K.2    Pathak, B.R.3
  • 46
    • 84963966440 scopus 로고    scopus 로고
    • Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls
    • Busch, A.S., Hagen, C.P., Almstrup, K., et al. Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls. Hum Reprod 31 (2016), 897–904.
    • (2016) Hum Reprod , vol.31 , pp. 897-904
    • Busch, A.S.1    Hagen, C.P.2    Almstrup, K.3
  • 47
    • 84865681750 scopus 로고    scopus 로고
    • Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome
    • Shi, Y., Zhao, H., Shi, Y., et al. Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet 44 (2012), 1020–1025, 10.1038/ng.2384.
    • (2012) Nat Genet , vol.44 , pp. 1020-1025
    • Shi, Y.1    Zhao, H.2    Shi, Y.3
  • 48
    • 67651087304 scopus 로고    scopus 로고
    • Clomiphene citrate resistance in relation to follicle-stimulating hormone receptor Ser680Ser-polymorphism in polycystic ovary syndrome
    • Overbeek, A., Kuijper, E.A.M., Hendriks, M.L., et al. Clomiphene citrate resistance in relation to follicle-stimulating hormone receptor Ser680Ser-polymorphism in polycystic ovary syndrome. Hum Reprod 24 (2009), 2007–2013, 10.1093/humrep/dep114.
    • (2009) Hum Reprod , vol.24 , pp. 2007-2013
    • Overbeek, A.1    Kuijper, E.A.M.2    Hendriks, M.L.3
  • 49
    • 84867182661 scopus 로고    scopus 로고
    • LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling
    • Casarini, L., Lispi, M., Longobardi, S., et al. LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling. PLoS One, 7, 2012, e46682, 10.1371/journal.pone.0046682.
    • (2012) PLoS One , vol.7 , pp. e46682
    • Casarini, L.1    Lispi, M.2    Longobardi, S.3
  • 50
    • 84956666390 scopus 로고    scopus 로고
    • Follicle-stimulating hormone potentiates the steroidogenic activity of chorionic gonadotropin and the anti-apoptotic activity of luteinizing hormone in human granulosa-lutein cells in vitro
    • Casarini, L., Riccetti, L., De Pascali, F., et al. Follicle-stimulating hormone potentiates the steroidogenic activity of chorionic gonadotropin and the anti-apoptotic activity of luteinizing hormone in human granulosa-lutein cells in vitro. Mol Cell Endocrinol 422 (2016), 103–114, 10.1016/j.mce.2015.12.008.
    • (2016) Mol Cell Endocrinol , vol.422 , pp. 103-114
    • Casarini, L.1    Riccetti, L.2    De Pascali, F.3
  • 51
    • 34548313698 scopus 로고    scopus 로고
    • Luteinizing hormone beta mutation and hypogonadism in men and women
    • Lofrano-Porto, A., Barra, G.B., Giacomini, L.A., et al. Luteinizing hormone beta mutation and hypogonadism in men and women. N Engl J Med 357 (2007), 897–904, 10.1056/NEJMoa071999.
    • (2007) N Engl J Med , vol.357 , pp. 897-904
    • Lofrano-Porto, A.1    Barra, G.B.2    Giacomini, L.A.3
  • 52
    • 70350754572 scopus 로고    scopus 로고
    • Normal spermatogenesis in a man with mutant luteinizing hormone
    • Achard, C., Courtillot, C., Lahuna, O., et al. Normal spermatogenesis in a man with mutant luteinizing hormone. N Engl J Med 361 (2009), 1856–1863, 10.1056/NEJMoa0805792.
    • (2009) N Engl J Med , vol.361 , pp. 1856-1863
    • Achard, C.1    Courtillot, C.2    Lahuna, O.3
  • 53
    • 84866148802 scopus 로고    scopus 로고
    • Hypogonadism in a patient with two novel mutations of the luteinizing hormone β-subunit gene expressed in a compound heterozygous form
    • Basciani, S., Watanabe, M., Mariani, S., et al. Hypogonadism in a patient with two novel mutations of the luteinizing hormone β-subunit gene expressed in a compound heterozygous form. J Clin Endocrinol Metab 97 (2012), 3031–3038, 10.1210/jc.2012-1986.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 3031-3038
    • Basciani, S.1    Watanabe, M.2    Mariani, S.3
  • 54
    • 84995842414 scopus 로고
    • Identification of two point mutations in the gene coding luteinizing hormone (LH) beta-subunit, associated with immunologically anomalous LH variants
    • Furui, K., Suganuma, N., Tsukahara, S., et al. Identification of two point mutations in the gene coding luteinizing hormone (LH) beta-subunit, associated with immunologically anomalous LH variants. J Clin Endocrinol Metab 78 (1994), 107–113, 10.1210/jcem.78.1.7904610.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 107-113
    • Furui, K.1    Suganuma, N.2    Tsukahara, S.3
  • 55
    • 0032893792 scopus 로고    scopus 로고
    • Increased prevalence of luteinizing hormone beta-subunit variant in patients with premature ovarian failure
    • Takahashi, K., Ozaki, T., Okada, M., et al. Increased prevalence of luteinizing hormone beta-subunit variant in patients with premature ovarian failure. Fertil Steril 71 (1999), 96–101.
    • (1999) Fertil Steril , vol.71 , pp. 96-101
    • Takahashi, K.1    Ozaki, T.2    Okada, M.3
  • 56
    • 0032775220 scopus 로고    scopus 로고
    • Association of molecular variants of luteinizing hormone with menstrual disorders
    • Ramanujam, L.N., Liao, W.X., Roy, A.C., et al. Association of molecular variants of luteinizing hormone with menstrual disorders. Clin Endocrinol (Oxf) 51 (1999), 243–246.
    • (1999) Clin Endocrinol (Oxf) , vol.51 , pp. 243-246
    • Ramanujam, L.N.1    Liao, W.X.2    Roy, A.C.3
  • 57
    • 84871221066 scopus 로고    scopus 로고
    • Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism
    • Alviggi, C., Clarizia, R., Pettersson, K., et al. Suboptimal response to GnRHa long protocol is associated with a common LH polymorphism. Reprod Biomed Online 22 (2011), S67–S72, 10.1016/S1472-6483(11)60011-4.
    • (2011) Reprod Biomed Online , vol.22 , pp. S67-S72
    • Alviggi, C.1    Clarizia, R.2    Pettersson, K.3
  • 58
    • 84878376382 scopus 로고    scopus 로고
    • A common polymorphic allele of the LH beta-subunit gene is associated with higher exogenous FSH consumption during controlled ovarian stimulation for assisted reproductive technology
    • Alviggi, C., Pettersson, K., Longobardi, S., et al. A common polymorphic allele of the LH beta-subunit gene is associated with higher exogenous FSH consumption during controlled ovarian stimulation for assisted reproductive technology. Reprod Biol Endocrinol, 11, 2013, 51, 10.1186/1477-7827-11-51.
    • (2013) Reprod Biol Endocrinol , vol.11 , pp. 51
    • Alviggi, C.1    Pettersson, K.2    Longobardi, S.3
  • 59
    • 0021260325 scopus 로고
    • The beta chorionic gonadotropin-beta luteinizing gene cluster maps to human chromosome 19
    • Julier, C., Weil, D., Couillin, P., et al. The beta chorionic gonadotropin-beta luteinizing gene cluster maps to human chromosome 19. Hum Genet 67 (1984), 174–177.
    • (1984) Hum Genet , vol.67 , pp. 174-177
    • Julier, C.1    Weil, D.2    Couillin, P.3
  • 60
    • 0017723084 scopus 로고
    • Isolation and amino acid sequence of COOH-terminal fragments from the beta subunit of human choriogonadotropin
    • Birken, S., Canfield, R.E., Isolation and amino acid sequence of COOH-terminal fragments from the beta subunit of human choriogonadotropin. J Biol Chem 252 (1977), 5386–5392.
    • (1977) J Biol Chem , vol.252 , pp. 5386-5392
    • Birken, S.1    Canfield, R.E.2
  • 61
    • 84999693706 scopus 로고    scopus 로고
    • Clinical applications of gonadotropins in the female: assisted reproduction and beyond
    • Casarini, L., Brigante, G., Simoni, M., et al. Clinical applications of gonadotropins in the female: assisted reproduction and beyond. Prog Mol Biol Transl Sci 143 (2016), 85–119, 10.1016/bs.pmbts.2016.08.002.
    • (2016) Prog Mol Biol Transl Sci , vol.143 , pp. 85-119
    • Casarini, L.1    Brigante, G.2    Simoni, M.3
  • 62
    • 33747050669 scopus 로고    scopus 로고
    • Recurrent miscarriage
    • Rai, R., Regan, L., Recurrent miscarriage. Lancet 368 (2006), 601–611, 10.1016/S0140-6736(06)69204-0.
    • (2006) Lancet , vol.368 , pp. 601-611
    • Rai, R.1    Regan, L.2
  • 63
    • 57349129548 scopus 로고    scopus 로고
    • Chorionic gonadotropin β-gene variants are associated with recurrent miscarriage in two European populations
    • Rull, K., Nagirnaja, L., Ulander, V.-M., et al. Chorionic gonadotropin β-gene variants are associated with recurrent miscarriage in two European populations. J Clin Endocrinol Metab 93 (2008), 4697–4706, 10.1210/jc.2008-1101.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4697-4706
    • Rull, K.1    Nagirnaja, L.2    Ulander, V.-M.3
  • 64
    • 34547411000 scopus 로고    scopus 로고
    • Genomic checkpoints for exon 10 usage in the luteinizing hormone receptor type 1 and type 2
    • Gromoll, J., Lahrmann, L., Godmann, M., et al. Genomic checkpoints for exon 10 usage in the luteinizing hormone receptor type 1 and type 2. Mol Endocrinol 21 (2007), 1984–1996, 10.1210/me.2006-0506.
    • (2007) Mol Endocrinol , vol.21 , pp. 1984-1996
    • Gromoll, J.1    Lahrmann, L.2    Godmann, M.3
  • 65
    • 0034456625 scopus 로고    scopus 로고
    • Male hypogonadism caused by homozygous deletion of exon 10 of the luteinizing hormone (LH) receptor: differential action of human chorionic gonadotropin and LH
    • Gromoll, J., Eiholzer, U., Nieschlag, E., et al. Male hypogonadism caused by homozygous deletion of exon 10 of the luteinizing hormone (LH) receptor: differential action of human chorionic gonadotropin and LH. J Clin Endocrinol Metab 85 (2000), 2281–2286, 10.1210/jcem.85.6.6636.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2281-2286
    • Gromoll, J.1    Eiholzer, U.2    Nieschlag, E.3
  • 66
    • 84994257349 scopus 로고    scopus 로고
    • Differences in signal activation by LH and hCG are mediated by the LH/CG receptor's extracellular hinge region
    • Grzesik, P., Kreuchwig, A., Rutz, C., et al. Differences in signal activation by LH and hCG are mediated by the LH/CG receptor's extracellular hinge region. Front Endocrinol (Lausanne), 2015, 6, 10.3389/fendo.2015.00140.
    • (2015) Front Endocrinol (Lausanne) , pp. 6
    • Grzesik, P.1    Kreuchwig, A.2    Rutz, C.3
  • 67
    • 0037775660 scopus 로고    scopus 로고
    • A new subclass of the luteinizing hormone/chorionic gonadotropin receptor lacking exon 10 messenger RNA in the New World monkey (Platyrrhini) lineage
    • Gromoll, J., Wistuba, J., Terwort, N., et al. A new subclass of the luteinizing hormone/chorionic gonadotropin receptor lacking exon 10 messenger RNA in the New World monkey (Platyrrhini) lineage. Biol Reprod 69 (2003), 75–80, 10.1095/biolreprod.102.014902.
    • (2003) Biol Reprod , vol.69 , pp. 75-80
    • Gromoll, J.1    Wistuba, J.2    Terwort, N.3
  • 68
    • 43249113471 scopus 로고    scopus 로고
    • Mutations in a novel, cryptic exon of the luteinizing hormone/chorionic gonadotropin receptor gene cause male pseudohermaphroditism
    • Kossack, N., Simoni, M., Richter-Unruh, A., et al. Mutations in a novel, cryptic exon of the luteinizing hormone/chorionic gonadotropin receptor gene cause male pseudohermaphroditism. PLoS Med, 5, 2008, e88, 10.1371/journal.pmed.0050088.
    • (2008) PLoS Med , vol.5 , pp. e88
    • Kossack, N.1    Simoni, M.2    Richter-Unruh, A.3
  • 69
    • 84872494236 scopus 로고    scopus 로고
    • Aberrant transcription of the LHCGR gene caused by a mutation in exon 6A leads to Leydig cell hypoplasia type II
    • Kossack, N., Troppmann, B., Richter-Unruh, A., et al. Aberrant transcription of the LHCGR gene caused by a mutation in exon 6A leads to Leydig cell hypoplasia type II. Mol Cell Endocrinol 366 (2013), 59–67, 10.1016/j.mce.2012.11.018.
    • (2013) Mol Cell Endocrinol , vol.366 , pp. 59-67
    • Kossack, N.1    Troppmann, B.2    Richter-Unruh, A.3
  • 70
    • 84883032068 scopus 로고    scopus 로고
    • Structural and functional plasticity of the luteinizing hormone/choriogonadotrophin receptor
    • Troppmann, B., Kleinau, G., Krause, G., et al. Structural and functional plasticity of the luteinizing hormone/choriogonadotrophin receptor. Hum Reprod Update 19 (2013), 583–602, 10.1093/humupd/dmt023.
    • (2013) Hum Reprod Update , vol.19 , pp. 583-602
    • Troppmann, B.1    Kleinau, G.2    Krause, G.3
  • 71
    • 0030025051 scopus 로고    scopus 로고
    • Brief report: testicular and ovarian resistance to luteinizing hormone caused by inactivating mutations of the luteinizing hormone-receptor gene
    • Latronico, A.C., Anasti, J., Arnhold, I.J., et al. Brief report: testicular and ovarian resistance to luteinizing hormone caused by inactivating mutations of the luteinizing hormone-receptor gene. N Engl J Med 334 (1996), 507–512, 10.1056/NEJM199602223340805.
    • (1996) N Engl J Med , vol.334 , pp. 507-512
    • Latronico, A.C.1    Anasti, J.2    Arnhold, I.J.3
  • 72
    • 0029843814 scopus 로고    scopus 로고
    • An inactivating mutation of the luteinizing hormone receptor causes amenorrhea in a 46,XX female
    • Toledo, S.P., Brunner, H.G., Kraaij, R., et al. An inactivating mutation of the luteinizing hormone receptor causes amenorrhea in a 46,XX female. J Clin Endocrinol Metab 81 (1996), 3850–3854, 10.1210/jcem.81.11.8923827.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3850-3854
    • Toledo, S.P.1    Brunner, H.G.2    Kraaij, R.3
  • 73
    • 0032230361 scopus 로고    scopus 로고
    • A homozygous microdeletion in Helix 7 of the luteinizing hormone receptor associated with familial testicular and ovarian resistance is due to both decreased cell surface expression and impaired effector activation by the cell surface receptor
    • Latronico, A.C., Chai, Y., Arnhold, I.J.P., et al. A homozygous microdeletion in Helix 7 of the luteinizing hormone receptor associated with familial testicular and ovarian resistance is due to both decreased cell surface expression and impaired effector activation by the cell surface receptor. Mol Endocrinol 12 (1998), 442–450, 10.1210/mend.12.3.0077.
    • (1998) Mol Endocrinol , vol.12 , pp. 442-450
    • Latronico, A.C.1    Chai, Y.2    Arnhold, I.J.P.3
  • 74
    • 0031732299 scopus 로고    scopus 로고
    • A novel mutation of the human luteinizing hormone receptor in 46XY and 46XX sisters
    • Stavrou, S.S., Zhu, Y.S., Cai, L.Q., et al. A novel mutation of the human luteinizing hormone receptor in 46XY and 46XX sisters. J Clin Endocrinol Metab 83 (1998), 2091–2098, 10.1210/jcem.83.6.4855.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2091-2098
    • Stavrou, S.S.1    Zhu, Y.S.2    Cai, L.Q.3
  • 75
    • 47649089467 scopus 로고    scopus 로고
    • A new LH receptor splice mutation responsible for male hypogonadism with subnormal sperm production in the propositus, and infertility with regular cycles in an affected sister
    • Bruysters, M., Christin-Maitre, S., Verhoef-Post, M., et al. A new LH receptor splice mutation responsible for male hypogonadism with subnormal sperm production in the propositus, and infertility with regular cycles in an affected sister. Hum Reprod 23 (2008), 1917–1923, 10.1093/humrep/den180.
    • (2008) Hum Reprod , vol.23 , pp. 1917-1923
    • Bruysters, M.1    Christin-Maitre, S.2    Verhoef-Post, M.3
  • 76
    • 58149145155 scopus 로고    scopus 로고
    • Inactivating mutations of luteinizing hormone β-subunit or luteinizing hormone receptor cause oligo-amenorrhea and infertility in women
    • Arnhold, I.J., Lofrano-Porto, A., Latronico, A.C., Inactivating mutations of luteinizing hormone β-subunit or luteinizing hormone receptor cause oligo-amenorrhea and infertility in women. Horm Res Paediatr 71 (2009), 75–82, 10.1159/000183895.
    • (2009) Horm Res Paediatr , vol.71 , pp. 75-82
    • Arnhold, I.J.1    Lofrano-Porto, A.2    Latronico, A.C.3
  • 77
    • 0042262627 scopus 로고    scopus 로고
    • Empty follicle syndrome in two sisters with three cycles: case report
    • Onalan, G., Pabuçcu, R., Onalan, R., et al. Empty follicle syndrome in two sisters with three cycles: case report. Hum Reprod 18 (2003), 1864–1867.
    • (2003) Hum Reprod , vol.18 , pp. 1864-1867
    • Onalan, G.1    Pabuçcu, R.2    Onalan, R.3
  • 78
    • 79960626975 scopus 로고    scopus 로고
    • Inherited mutation of the luteinizing hormone/choriogonadotropin receptor (LHCGR) in empty follicle syndrome
    • Yariz, K.O., Walsh, T., Uzak, A., et al. Inherited mutation of the luteinizing hormone/choriogonadotropin receptor (LHCGR) in empty follicle syndrome. Fertil Steril 96 (2011), e125–e130, 10.1016/j.fertnstert.2011.05.057.
    • (2011) Fertil Steril , vol.96 , pp. e125-e130
    • Yariz, K.O.1    Walsh, T.2    Uzak, A.3
  • 79
    • 84860327967 scopus 로고    scopus 로고
    • A novel luteinizing hormone/chorionic gonadotropin receptor mutation associated with amenorrhea, low oocyte yield, and recurrent pregnancy loss
    • Bentov, Y., Kenigsberg, S., Casper, R.F., A novel luteinizing hormone/chorionic gonadotropin receptor mutation associated with amenorrhea, low oocyte yield, and recurrent pregnancy loss. Fertil Steril 97 (2012), 1165–1168, 10.1016/j.fertnstert.2012.02.002.
    • (2012) Fertil Steril , vol.97 , pp. 1165-1168
    • Bentov, Y.1    Kenigsberg, S.2    Casper, R.F.3
  • 80
    • 0029840021 scopus 로고    scopus 로고
    • Response to challenge with gonadotropin-releasing hormone agonist in a mother and her two sons with a constitutively activating mutation of the luteinizing hormone receptor–a clinical research center study
    • Rosenthal, I.M., Refetoff, S., Rich, B., et al. Response to challenge with gonadotropin-releasing hormone agonist in a mother and her two sons with a constitutively activating mutation of the luteinizing hormone receptor–a clinical research center study. J Clin Endocrinol Metab 81 (1996), 3802–3806, 10.1210/jcem.81.10.8855841.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3802-3806
    • Rosenthal, I.M.1    Refetoff, S.2    Rich, B.3
  • 81
    • 0027372340 scopus 로고
    • A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
    • Shenker, A., Laue, L., Kosugi, S., et al. A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. Nature 365 (1993), 652–654, 10.1038/365652a0.
    • (1993) Nature , vol.365 , pp. 652-654
    • Shenker, A.1    Laue, L.2    Kosugi, S.3
  • 82
    • 0033748221 scopus 로고    scopus 로고
    • The effect of distinct activating mutations of the luteinizing hormone receptor gene on the pituitary-gonadal axis in both sexes
    • Latronico, A.C., Lins, T.S., Brito, V.N., et al. The effect of distinct activating mutations of the luteinizing hormone receptor gene on the pituitary-gonadal axis in both sexes. Clin Endocrinol (Oxf) 53 (2000), 609–613.
    • (2000) Clin Endocrinol (Oxf) , vol.53 , pp. 609-613
    • Latronico, A.C.1    Lins, T.S.2    Brito, V.N.3
  • 83
    • 84955171199 scopus 로고    scopus 로고
    • Association between genes encoding components of the leutinizing hormone/luteinizing hormone-choriogonadotrophin receptor pathway and polycystic ovary syndrome in Egyptian women
    • El-Shal, A.S., Zidan, H.E., Rashad, N.M., et al. Association between genes encoding components of the leutinizing hormone/luteinizing hormone-choriogonadotrophin receptor pathway and polycystic ovary syndrome in Egyptian women. IUBMB Life 68 (2016), 23–36.
    • (2016) IUBMB Life , vol.68 , pp. 23-36
    • El-Shal, A.S.1    Zidan, H.E.2    Rashad, N.M.3
  • 84
    • 84862012197 scopus 로고    scopus 로고
    • The 312N variant of the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) confers up to 2·7-fold increased risk of polycystic ovary syndrome in a Sardinian population
    • Capalbo, A., Sagnella, F., Apa, R., et al. The 312N variant of the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) confers up to 2·7-fold increased risk of polycystic ovary syndrome in a Sardinian population. Clin Endocrinol (Oxf) 77 (2012), 113–119.
    • (2012) Clin Endocrinol (Oxf) , vol.77 , pp. 113-119
    • Capalbo, A.1    Sagnella, F.2    Apa, R.3
  • 85
    • 40049094341 scopus 로고    scopus 로고
    • Polymorphisms of the luteinizing hormone/chorionic gonadotropin receptor gene: association with maldescended testes and male infertility
    • Simoni, M., Tüttelmann, F., Michel, C., et al. Polymorphisms of the luteinizing hormone/chorionic gonadotropin receptor gene: association with maldescended testes and male infertility. Pharmacogenet Genomics 18 (2008), 193–200, 10.1097/FPC.0b013e3282f4e98c.
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 193-200
    • Simoni, M.1    Tüttelmann, F.2    Michel, C.3
  • 86
    • 84924348216 scopus 로고    scopus 로고
    • Association of luteinizing hormone chorionic gonadotropin receptor gene polymorphism (rs2293275) with polycystic ovarian syndrome
    • Thathapudi, S., Kodati, V., Erukkambattu, J., et al. Association of luteinizing hormone chorionic gonadotropin receptor gene polymorphism (rs2293275) with polycystic ovarian syndrome. Genet Test Mol Biomark 19 (2015), 128–132, 10.1089/gtmb.2014.0249.
    • (2015) Genet Test Mol Biomark , vol.19 , pp. 128-132
    • Thathapudi, S.1    Kodati, V.2    Erukkambattu, J.3
  • 87
    • 84863224246 scopus 로고    scopus 로고
    • LH receptor gene expression in cumulus cells in women entering an ART program
    • Papamentzelopoulou, M., Mavrogianni, D., Partsinevelos, G.A., et al. LH receptor gene expression in cumulus cells in women entering an ART program. J Assist Reprod Genet 29 (2012), 409–416, 10.1007/s10815-012-9729-7.
    • (2012) J Assist Reprod Genet , vol.29 , pp. 409-416
    • Papamentzelopoulou, M.1    Mavrogianni, D.2    Partsinevelos, G.A.3
  • 88
    • 0031945479 scopus 로고    scopus 로고
    • Premature luteinization: could it be an early manifestation of low ovarian reserve?
    • Younis, J.S., Haddad, S., Matilsky, M., et al. Premature luteinization: could it be an early manifestation of low ovarian reserve?. Fertil Steril 69 (1998), 461–465.
    • (1998) Fertil Steril , vol.69 , pp. 461-465
    • Younis, J.S.1    Haddad, S.2    Matilsky, M.3
  • 89
    • 84866607665 scopus 로고    scopus 로고
    • Combined effects of the variants FSHB −211G>T and FSHR 2039A>G on male reproductive parameters
    • Tüttelmann, F., Laan, M., Grigorova, M., et al. Combined effects of the variants FSHB −211G>T and FSHR 2039A>G on male reproductive parameters. J Clin Endocrinol Metab 97 (2012), 3639–3647, 10.1210/jc.2012-1761.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 3639-3647
    • Tüttelmann, F.1    Laan, M.2    Grigorova, M.3
  • 90
    • 84960193221 scopus 로고    scopus 로고
    • Combined assessment of polymorphisms in the LHCGR and FSHR genes predict chance of pregnancy after in vitro fertilization
    • Lindgren, I., Bååth, M., Uvebrant, K., et al. Combined assessment of polymorphisms in the LHCGR and FSHR genes predict chance of pregnancy after in vitro fertilization. Hum Reprod 31 (2016), 672–683, 10.1093/humrep/dev342.
    • (2016) Hum Reprod , vol.31 , pp. 672-683
    • Lindgren, I.1    Bååth, M.2    Uvebrant, K.3
  • 91
    • 85031856220 scopus 로고    scopus 로고
    • The carriers of the A/G-G/G allelic combination of the c.2039 A>G and c.-29 G>A FSH receptor polymorphisms retrieve the highest number of oocytes in IVF/ICSI cycles
    • Allegra, A., Marino, A., Raimondo, S., et al. The carriers of the A/G-G/G allelic combination of the c.2039 A>G and c.-29 G>A FSH receptor polymorphisms retrieve the highest number of oocytes in IVF/ICSI cycles. J Assist Reprod Genet, 2016.
    • (2016) J Assist Reprod Genet
    • Allegra, A.1    Marino, A.2    Raimondo, S.3
  • 92
    • 84886252742 scopus 로고    scopus 로고
    • Two sexes, one genome: the evolutionary dynamics of intralocus sexual conflict
    • Pennell, T.M., Morrow, E.H., Two sexes, one genome: the evolutionary dynamics of intralocus sexual conflict. Ecol Evol 3 (2013), 1819–1834.
    • (2013) Ecol Evol , vol.3 , pp. 1819-1834
    • Pennell, T.M.1    Morrow, E.H.2
  • 93
    • 84957900819 scopus 로고    scopus 로고
    • Is polycystic ovary syndrome a sexual conflict? A review
    • Casarini, L., Simoni, M., Brigante, G., Is polycystic ovary syndrome a sexual conflict? A review. Reprod Biomed Online 32 (2016), 350–361, 10.1016/j.rbmo.2016.01.011.
    • (2016) Reprod Biomed Online , vol.32 , pp. 350-361
    • Casarini, L.1    Simoni, M.2    Brigante, G.3
  • 94
    • 84909998765 scopus 로고    scopus 로고
    • The polycystic ovary syndrome evolutionary paradox: a genome-wide association studies-based, in silico, evolutionary explanation
    • Casarini, L., Brigante, G., The polycystic ovary syndrome evolutionary paradox: a genome-wide association studies-based, in silico, evolutionary explanation. J Clin Endocrinol Metab 99 (2014), E2412–E2420.
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E2412-E2420
    • Casarini, L.1    Brigante, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.