Unsaturated Fatty Acids Improve Atherosclerosis Markers in Obese and Overweight Non-diabetic Elderly Patients

Obesity Surgery

Volumn 27, Issue 10, 2017, Pages 2663-2671

  de Oliveira, Patrícia Amante ^a,b,c   Kovacs, Cristiane ^c   Moreira, Priscila ^c   Magnoni, Daniel ^c   Saleh, Mohamed Hassan ^c   Faintuch, Joel ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Dante Pazzanese Institute of Cardiology ^*  (Brazil)

^c INSTITUTO DANTE PAZZANESE DE CARDIOLOGIA   (Brazil)

Author keywords

Atherosclerosis; Carotid intima media thickness; Elderly; Inflammation; Obesity; Unsaturated fatty acids; Vascular endothelium; Vascular stiffness

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN B; C REACTIVE PROTEIN; LINSEED OIL; MARKER; OLIVE OIL; SUNFLOWER OIL; UNSATURATED FATTY ACID; BIOLOGICAL MARKER; EDIBLE OIL; VEGETABLE OIL;

ADULT; AGED; ANTHROPOMETRIC PARAMETERS; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; BIOCHEMICAL ANALYSIS; BRACHIAL ARTERY; CAROTID ARTERY; CONTROLLED STUDY; DIET; DOUBLE BLIND PROCEDURE; ECHOGRAPHY; ENDOTHELIUM; FEMALE; HUMAN; IMPEDANCE; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUPPLEMENTATION; VASODILATATION; BLOOD; CARDIOVASCULAR DISEASE; COMPLICATION; DIET THERAPY; DIETARY SUPPLEMENT; MIDDLE AGED; PATHOPHYSIOLOGY; RISK FACTOR; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ATHEROSCLEROSIS; BIOMARKERS; CARDIOVASCULAR DISEASES; CAROTID INTIMA-MEDIA THICKNESS; DIETARY FATS, UNSATURATED; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FATTY ACIDS, UNSATURATED; FEMALE; HUMANS; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; PLANT OILS; RISK FACTORS;

EID: 85018975713     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-017-2704-8     Document Type: Article

References (49)

1. Adams KF, Schatzkin A, Harris TB, et al. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med. 2006;355:763–78.
2. Scaglione R, Argano C, Di CT, et al. Obesity and cardiovascular risk: the new public health problem of worldwide proportions. Expert Rev Cardiovasc Ther. 2004;2(2):203–12.
3. Jazet IM, Pijl H, Meinders AE. Adipose tissue as an endocrine organ: impact on insulin resistance. Neth J Med. 2003;61(6):194–212.
4. McGown C, Birerdinc A, Younossi ZM. Adipose tissue as an endocrine organ. Clin Liver Dis. 2014;18(1):41–58.
5. Safar ME, Thomas F, Blacher J, et al. Metabolic syndrome and age-related progression of aortic stiffness. J Am Coll Cardiol. 2006;47(1):72–5.
6. Simopoulos AP. Evolutionary aspects of the dietary omega-6:omega-3 fatty acid ratio: medical implications. World Rev Nutr Diet. 2009;100:1–21.
7. Abdelmagid SM, Barbe MF, Safadi FF. Role of inflammation in the aging bones. Life Sci. 2015;123:25–34.
8. Aharoni S, Lati Y, Aviram M, et al. Pomegranate juice polyphenols induce a phenotypic switch in macrophage polarization favoring a M2 anti-inflammatory state. Biofactors. 2015;41(1):44–51.
9. Wu J, Xia S, Kalionis B, et al. The role of oxidative stress and inflammation in cardiovascular aging. Biomed Res Int. 2014;2014:615312.
10. Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006;444:875–80.
11. Saleh MH, Bertolami MC, Assef JE, et al. Improvement of atherosclerotic markers in non-diabetic patients after bariatric surgery. Obes Surg. 2012;22(11):1701–7.
12. Simopoulos AP. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med. 2008;233:674–68.
13. Dittrich M, Jahreis G, Bothor K, et al. Benefits of foods supplemented with vegetable oils rich in α-linolenic, stearidonic or docosahexaenoic acid in hpertriglyceridemic subjects: a double-blind, randomized, controlled trail. Eur J Nutr. 2015;54:881–93.
14. Burdge G. Alpha-linolenic acid metabolism in men and women: nutritional and biological implications. Curr Opin Clin Nutr Metab Care. 2004;7:137–44.
15. Barceló-Coblijn G, Murphy EJ. Alpha-linolenic acid and its conversion to long chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels. Prog Lipid Res. 2009;48:355–74.
16. Goyens PLL, Spilker ME, Zock PL, et al. Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio. Am J Clin Nutr. 2006;84:44–53.
17. Wien M, Rajaram S, Oda K, et al. Decreasing the linoleic acid to alpha-linolenic acid diet ratio increases eicosapentaenoic acid in erythrocytes in adults. Lipids. 2010;45:683–92.
18. Khalesi S, Irwin C, Schubert M. Flaxseed consumption may reduce blood pressure: a systematic review and meta-analysis of controlled trials. J Nutr. 2015;145:758–65.
19. Hooper L, Summerbell CD, Thompson R, et al. Reduced or modified dietary fat for preventing cardiovascular disease. Cochrane Database Syst Rev. 2012;5:CD002137.
20. Shen J, Wilmot KA, Ghasemzadeh N, et al. Mediterranean dietary patterns and cardiovascular health. Annu Rev Nutr. 2015;35:425–49.
21. Perona JS, Cabello-Moruno R, Ruiz-Gutierrez V. The role of virgin olive oil components in the modulation of endothelial function. J Nut Biochem. 2006;17(7):429–45.
22. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report. Circulation. 2002;106:3143–421.
23. de Oliveira MF, Vieira OV. Extração de Óleo de Girassol Utilizando Miniprensa [Internet]. Brazilian Agricultural Research Corporation: Ministry of Agriculture, Livestock, and Food Supply; 2004 [cited. May 23. 2015; Available from: http://www.cnpso.embrapa.br/download/publicacao/documento_237.pdf
24. Correti MC, Anderson TJ, Benjamin EJ, et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilatation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol. 2002;39:257–65.
25. Teixeira HNP, Mesquita ET, Ribeiro ML, et al. Estudo da reatividade vascular em portadores de HIV com e sem uso de inibidor de protease. Arq Bras Cardiol. 2009;93(4):367–73.
26. Kim OY, Paik JK, Lee JY, et al. Follow-ups of metabolic, inflammatory and oxidative stress markers, and brachial-ankle pulse wave velocity in middle-aged subjects without metabolic syndrome. Clin Exp Hypertens. 2013;35(5):382–8.
27. Barceló-Coblijn G, Murphy EJ, Othman R, et al. Flaxseed oil and fish-oil capsule consumption alters human red blood cell n–3 fatty acid composition: a multiple-dosing trial comparing 2 sources of n–3 fatty acid. Am J Clin Nutr. 2008;88:801–9.
28. de Lorgeril M, Salen P, Martin JL, et al. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation. 1999;99:779–85.
29. Rastogi T, Reddy KS, Vaz M, et al. Diet and risk of ischemic heart disease in India. Am J Clin Nutr. 2004;79:582–92.
30. Derbali A, Mnafgui K, Affes M, et al. Cardioprotective effect of linseed oil against isoproterenol-induced myocardial infarction in Wistar rats: a biochemical and electrocardiographic study. J Physiol Biochem. 2015;71:281–8.
31. Zhao G, Etherton TD, Martin KR, et al. Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women. J Nutr. 2004;134:2991–7.
32. Bemelmans WJ, Lefrandt JD, Feskens EJ, et al. Increased alpha-linolenic acid intake lowers C-reactive protein, but has no effect on markers of atherosclerosis. Eur J Clin Nutr. 2004;58:1083–9.
33. Satoh N, Shimatsu A, Kotani K, et al. Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome. Hyperten Res. 2009;32:1004–8.
34. Huth PJ, Fulgoni 3rd VL, Larson BT. A systematic review of high-oleic vegetable oil substitutions for other fats and oils on cardiovascular disease risk factors: implications for novel high-oleic soybean oils. Adv Nutr. 2015;6:674–93.
35. Ramsden CE, Zamora D, Leelarthaepin B, et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. BMJ. 2013;346:e8707.
36. Woodhill JM, Palmer AJ, Leelarthaepin B, et al. Low fat, low cholesterol diet in secondary prevention of coronary heart disease. Adv Exp Med Biol. 1978;109:317–30.
37. Modena MG, Bonetti L, Coppi F, et al. Prognostic role of reversible endothelial dysfunction in hypertensive postmenopausal women. J Am Coll Cardiol. 2002;40:505–10.
38. Saleh MH. O impacto da cirurgia bariátrica na função endothelial, variáveis ecocardiográficas e perfil inflamatório [dissertation]. Instituto Dante Pazzanese de Cardiologia: São Paulo, Brazil; 2011.
39. Schiano V, Laurenzano E, Brevetti G, et al. Omega-3 polyunsaturated fatty acid in peripheral arterial disease: effect on lipid pattern, disease severity, inflammation profile, and endothelial function. Clin Nutr. 2008;27:241–7.
40. Tousoulis D, Plastiras A, Siasos G, et al. Omega-3 PUFAs improved endothelial function and arterial stiffness with a parallel anti-inflammatory effect in adults with metabolic syndrome. Atherosclerosis. 2014;232:10–6.
41. Goodfellow J, Bellamy MF, Ramsey MW, et al. Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia. J Am Coll Cardiol. 2000;35:265e70.
42. Siasos G, Tousoulis D, Oikonomou E, et al. Effects of omega-3 fatty acids on endothelial function, arterial wall properties, inflammatory and fibrinolytic status in smokers: a cross over study. Int J Cardiol. 2013;166:340–6.
43. Din JN, Archer RM, Harding SA, et al. Effect of ω-3 fatty acid supplementation on endothelial function, endogenous fibrinolysis and platelet activation in male cigarette smokers. Heart. 2013;99(3):168–74.
44. Tomiyama H, Takazawa K, Osa S, et al. Do eicosapentaenoic acid supplements attenuate age-related increases in arterial stiffness in patients with dyslipidemia? A preliminary study. Hypertens Res. 2005;28:651–5.
45. Takaki A, Umemoto S, Ono K, et al. Add-on therapy of EPA reduces oxidative stress and inhibits the progression of aortic stiffness in patients with coronary artery disease and statin therapy: a randomized controlled study. J Atheroscler Thromb. 2011;18(10):857–66.
46. Tolezani EC. Determinantes das propriedades funcionais e estruturais de grandes artérias em uma população de indivíduos adultos saudáveis [dissertation]. São Paulo: Universidade de São Paulo; 2012.
47. Angerer P, Kothny W, Störk S, et al. Effect of dietary supplementation with v-3 fatty acids on progression of atherosclerosis in carotid arteries. Cardiovasc Res. 2002;54:183–90.
48. Augustine AH, Lowenstein LM, Harris WS, et al. Treatment with omega-3 fatty acid ethyl-ester alters fatty acid composition of lipoproteins in overweight or obese adults with insulin resistance. Prostaglandins Leukot Essent Fatty Acids. 2014;90(2–3):69–75.
49. Mackay I, Ford I, Thies F, et al. Effect of omega-3 fatty acid supplementation on markers of platelet and endothelial function in patients with peripheral arterial disease. Atherosclerosis. 2012;221:514–20.