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Volumn 17, Issue 1, 2017, Pages

When more is less: Emergent suppressive interactions in three-drug combinations

Author keywords

Antagonism; Antibiotics; Drug resistance; Higher order interactions; Multiple stressors

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; CEFOXITIN; CHLORAMPHENICOL; CIPROFLOXACIN; CLINDAMYCIN; DOXYCYCLINE; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; NITROFURANTOIN; STREPTOMYCIN; TOBRAMYCIN; TRIMETHOPRIM; VANCOMYCIN; ANTIINFECTIVE AGENT;

EID: 85018775866     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/s12866-017-1017-3     Document Type: Article
Times cited : (24)

References (49)
  • 2
    • 78751477224 scopus 로고    scopus 로고
    • Challenges of antibacterial discovery
    • 1:CAS:528:DC%2BC3MXjtFSgu7s%3D 21233508 3021209
    • Silver LL. Challenges of antibacterial discovery. Clin Microbiol Rev. 2011;24:71-109.
    • (2011) Clin Microbiol Rev , vol.24 , pp. 71-109
    • Silver, L.L.1
  • 3
    • 77957980707 scopus 로고    scopus 로고
    • Origins and evolution of Antibiotic resistance
    • 1:CAS:528:DC%2BC3cXhsVSqurnO 20805405 2937522
    • Davies J, Davies D. Origins and evolution of Antibiotic resistance. Microbiol Mol Biol Rev. 2010;74:417-33.
    • (2010) Microbiol Mol Biol Rev , vol.74 , pp. 417-433
    • Davies, J.1    Davies, D.2
  • 4
    • 79956079536 scopus 로고    scopus 로고
    • Antibiotic adjuvants: multicomponent anti-infective strategies
    • Kalan L, Wright G. Antibiotic adjuvants: multicomponent anti-infective strategies. Expert Reviews Mol Med. 2011;13:e5.
    • (2011) Expert Reviews Mol Med , vol.13 , pp. e5
    • Kalan, L.1    Wright, G.2
  • 5
    • 52949141463 scopus 로고    scopus 로고
    • Accelerated evolution of resistance in multidrug environments
    • 1:CAS:528:DC%2BD1cXhtFKiurfI 18779569 2544564
    • Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R. Accelerated evolution of resistance in multidrug environments. Proc Natl Acad Sci U S A. 2008;105:13977-81.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13977-13981
    • Hegreness, M.1    Shoresh, N.2    Damian, D.3    Hartl, D.4    Kishony, R.5
  • 6
    • 0000419454 scopus 로고
    • Die Mischiarnei
    • Loewe S. Die Mischiarnei. Klin Wochenschr. 1927;6:1077-85.
    • (1927) Klin Wochenschr , vol.6 , pp. 1077-1085
    • Loewe, S.1
  • 7
    • 84946384873 scopus 로고
    • The toxicity of poisons applied jointly
    • 1:CAS:528:DyaH3cXhtFWq
    • Bliss CI. The toxicity of poisons applied jointly. Ann Appl Biol. 1939;26:585-615.
    • (1939) Ann Appl Biol , vol.26 , pp. 585-615
    • Bliss, C.I.1
  • 8
    • 65649124513 scopus 로고    scopus 로고
    • Drug interactions and the evolution of antibiotic resistance
    • 1:CAS:528:DC%2BD1MXlvFSiu7s%3D 19444248 2855488
    • Yeh PJ, Hegreness MJ, Aiden AP, Kishony R. Drug interactions and the evolution of antibiotic resistance. Nat Rev Microbiol. 2009;7:460-6.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 460-466
    • Yeh, P.J.1    Hegreness, M.J.2    Aiden, A.P.3    Kishony, R.4
  • 9
    • 0015484953 scopus 로고
    • Clinical significance of in vitro synergism between antibiotics in gram-negative infections
    • 1:STN:280:DyaE2c7lsFCmsw%3D%3D 4596743 444341
    • Klastersky J, Cappel R, Daneau D. Clinical significance of in vitro synergism between antibiotics in gram-negative infections. Antimicrob Agents Chemother. 1972;2:470-5.
    • (1972) Antimicrob Agents Chemother , vol.2 , pp. 470-475
    • Klastersky, J.1    Cappel, R.2    Daneau, D.3
  • 10
    • 0001251342 scopus 로고
    • Lecture on the antagonism between the actions of active substances
    • 1:STN:280:DC%2BC3MzgvVSktw%3D%3D 20746808 2294062
    • Fraser TR. Lecture on the antagonism between the actions of active substances. Br Med J. 1872;2:457-9.
    • (1872) Br Med J , vol.2 , pp. 457-459
    • Fraser, T.R.1
  • 11
    • 33645396484 scopus 로고    scopus 로고
    • Functional classification of drugs by properties of their pairwise interactions
    • 1:CAS:528:DC%2BD28XivFSht7g%3D 16550172
    • Yeh P, Tschumi AI, Kishony R. Functional classification of drugs by properties of their pairwise interactions. Nat Genet. 2006;38:489-94.
    • (2006) Nat Genet , vol.38 , pp. 489-494
    • Yeh, P.1    Tschumi, A.I.2    Kishony, R.3
  • 12
    • 0015380117 scopus 로고
    • Combinations of antimicrobials
    • 40-&
    • Jawetz E, Smith L. Combinations of antimicrobials. Calif Med. 1972;117:40-&.
    • (1972) Calif Med , vol.117
    • Jawetz, E.1    Smith, L.2
  • 13
    • 34247277741 scopus 로고    scopus 로고
    • Antibiotic interactions that select against resistance
    • 1:CAS:528:DC%2BD2sXjslOlsbo%3D 17410176
    • Chait R, Craney A, Kishony R. Antibiotic interactions that select against resistance. Nature. 2007;446:668-71.
    • (2007) Nature , vol.446 , pp. 668-671
    • Chait, R.1    Craney, A.2    Kishony, R.3
  • 14
    • 54449092082 scopus 로고    scopus 로고
    • Drug interactions modulate the potential for evolution of resistance
    • 1:CAS:528:DC%2BD1cXht1aqur%2FO 18815368 2567468
    • Michel JB, Yeh PJ, Chait R, Moellering RC, Kishony R. Drug interactions modulate the potential for evolution of resistance. Proc Natl Acad Sci U S A. 2008;105:14918-23.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14918-14923
    • Michel, J.B.1    Yeh, P.J.2    Chait, R.3    Moellering, R.C.4    Kishony, R.5
  • 15
    • 77955480115 scopus 로고    scopus 로고
    • Optimal drug synergy in antimicrobial treatments
    • 20532210 2880566
    • Torella JP, Chait R, Kishony R. Optimal drug synergy in antimicrobial treatments. PLoS Comput Biol. 2010;6:e1000796.
    • (2010) PLoS Comput Biol , vol.6 , pp. e1000796
    • Torella, J.P.1    Chait, R.2    Kishony, R.3
  • 17
    • 84864369297 scopus 로고    scopus 로고
    • Mechanism-independent method for predicting response to multidrug combinations in bacteria
    • 1:CAS:528:DC%2BC38Xht1GktbjF 22773816 3409729
    • Wood K, Nishida S, Sontag ED, Cluzel P. Mechanism-independent method for predicting response to multidrug combinations in bacteria. Proc Natl Acad Sci U S A. 2012;109:12254-9.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 12254-12259
    • Wood, K.1    Nishida, S.2    Sontag, E.D.3    Cluzel, P.4
  • 19
    • 84983087709 scopus 로고    scopus 로고
    • Enhanced identification of synergistic and antagonistic emergent interactions among three or more drugs
    • Tekin E, Beppler C, White C, Mao Z, Savage VM, Yeh PJ. Enhanced identification of synergistic and antagonistic emergent interactions among three or more drugs. J R Soc Interface. 2016;13:119.
    • (2016) J R Soc Interface. , vol.13 , pp. 119
    • Tekin, E.1    Beppler, C.2    White, C.3    Mao, Z.4    Savage, V.M.5    Yeh, P.J.6
  • 20
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • 1:CAS:528:DC%2BD3cXktFais7c%3D 10829079 18686
    • Datsenko K, Wanner B. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A. 2000;97:6640-5.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6640-6645
    • Datsenko, K.1    Wanner, B.2
  • 22
    • 84874720377 scopus 로고    scopus 로고
    • Killing by bactericidal antibiotics does not depend on reactive oxygen species
    • 1:CAS:528:DC%2BC3sXjtlyksL8%3D 23471410
    • Keren I, Wu Y, Inocencio J, Mulcahy JR, Lewis K. Killing by bactericidal antibiotics does not depend on reactive oxygen species. Science. 2013;339:1213-6.
    • (2013) Science , vol.339 , pp. 1213-1216
    • Keren, I.1    Wu, Y.2    Inocencio, J.3    Mulcahy, J.R.4    Lewis, K.5
  • 26
    • 84920148375 scopus 로고    scopus 로고
    • Synergistic interactions of vancomycin with different antibiotics against Escherichia coli: trimethoprim and nitrofurantoin display strong synergies with vancomycin against wild-type E. coli
    • 25348521
    • Zhou A, Kang TM, Yuan J, Beppler C, Nguyen C, Mao Z, Nguyen MQ, Yeh P, Miller JH. Synergistic interactions of vancomycin with different antibiotics against Escherichia coli: trimethoprim and nitrofurantoin display strong synergies with vancomycin against wild-type E. coli. Antimicrob Agents Chemother. 2015;59:276-81.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 276-281
    • Zhou, A.1    Kang, T.M.2    Yuan, J.3    Beppler, C.4    Nguyen, C.5    Mao, Z.6    Nguyen, M.Q.7    Yeh, P.8    Miller, J.H.9
  • 28
    • 33748698411 scopus 로고    scopus 로고
    • The world of subinhibitory antibiotic concentrations
    • 1:CAS:528:DC%2BD28XpvFSis7s%3D 16942902
    • Davies J, Spiegelman GB, Yim G. The world of subinhibitory antibiotic concentrations. Curr Opin Microbiol. 2006;9:445-53.
    • (2006) Curr Opin Microbiol , vol.9 , pp. 445-453
    • Davies, J.1    Spiegelman, G.B.2    Yim, G.3
  • 29
    • 33644871218 scopus 로고    scopus 로고
    • The truth about antibiotics
    • 1:CAS:528:DC%2BD28XksFSru7o%3D 16503195
    • Yim G, Wang HH, Davies J. The truth about antibiotics. Int J Med Microbiol. 2006;296:163-70.
    • (2006) Int J Med Microbiol , vol.296 , pp. 163-170
    • Yim, G.1    Wang, H.H.2    Davies, J.3
  • 30
    • 33845884076 scopus 로고    scopus 로고
    • Antibiotics as intermicrobial signaling agents instead of weapons
    • 1:CAS:528:DC%2BD2sXhs1yrtQ%3D%3D 17148599 1682013
    • Linares JF, Gustafsson I, Baquero F, Martinez JL. Antibiotics as intermicrobial signaling agents instead of weapons. Proc Natl Acad Sci U S A. 2006;103:19484-9.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19484-19489
    • Linares, J.F.1    Gustafsson, I.2    Baquero, F.3    Martinez, J.L.4
  • 32
    • 11244297914 scopus 로고    scopus 로고
    • Modular epistasis in yeast metabolism
    • 1:CAS:528:DC%2BD2cXhtFChsLzJ 15592468
    • Segre D, DeLuna A, Church G, Kishony R. Modular epistasis in yeast metabolism. Nat Genet. 2005;37:77-83.
    • (2005) Nat Genet , vol.37 , pp. 77-83
    • Segre, D.1    DeLuna, A.2    Church, G.3    Kishony, R.4
  • 33
    • 33749242962 scopus 로고    scopus 로고
    • Epistasis correlates to genomic complexity
    • 16983079 1599975
    • Sanjuán R, Elena SF. Epistasis correlates to genomic complexity. Proc Natl Acad Sci U S A. 2006;103:14402-5.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14402-14405
    • Sanjuán, R.1    Elena, S.F.2
  • 34
    • 77649182884 scopus 로고    scopus 로고
    • Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks
    • 1:CAS:528:DC%2BC3cXhtVWrtb0%3D 20101242 2837480
    • He X, Qian W, Wang Z, Li Y, Zhang J. Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks. Nat Genet. 2010;42:272-6.
    • (2010) Nat Genet , vol.42 , pp. 272-276
    • He, X.1    Qian, W.2    Wang, Z.3    Li, Y.4    Zhang, J.5
  • 35
    • 84986879765 scopus 로고    scopus 로고
    • Prediction of multidimensional drug dose responses based on measurements of drug pairs
    • 1:CAS:528:DC%2BC28XhsVWjtrnF 27562164 5027409
    • Zimmer A, Katzir I, Dekel E, Mayo AE, Alon U. Prediction of multidimensional drug dose responses based on measurements of drug pairs. Proc Natl Acad Sci U S A. 2016;113:10442-7.
    • (2016) Proc Natl Acad Sci U S A , vol.113 , pp. 10442-10447
    • Zimmer, A.1    Katzir, I.2    Dekel, E.3    Mayo, A.E.4    Alon, U.5
  • 38
    • 70350769418 scopus 로고    scopus 로고
    • Non-optimal microbial response to antibiotics underlies suppressive drug interactions
    • 1:CAS:528:DC%2BD1MXhsFylsbbN 19914165 2838386
    • Bollenbach T, Quan S, Chait R, Kishony R. Non-optimal microbial response to antibiotics underlies suppressive drug interactions. Cell. 2009;139:707-18.
    • (2009) Cell , vol.139 , pp. 707-718
    • Bollenbach, T.1    Quan, S.2    Chait, R.3    Kishony, R.4
  • 39
    • 77950836148 scopus 로고    scopus 로고
    • Comparative pharmacodynamic interaction analysis of triple combinations of caspofungin and voriconazole or ravuconazole with subinhibitory concentrations of amphotericin B against Aspergillus spp
    • 1:CAS:528:DC%2BC3cXmtFOhur4%3D 19389068
    • Demchok J, Meletiadis J, Roilides E, Walsh T. Comparative pharmacodynamic interaction analysis of triple combinations of caspofungin and voriconazole or ravuconazole with subinhibitory concentrations of amphotericin B against Aspergillus spp. Mycoses. 2010;53:239-45.
    • (2010) Mycoses , vol.53 , pp. 239-245
    • Demchok, J.1    Meletiadis, J.2    Roilides, E.3    Walsh, T.4
  • 40
    • 74249121667 scopus 로고    scopus 로고
    • Inhibition of Staphylococcus aureus in broth and meat broth using synergies of phenolics and organic acids
    • 20004993
    • de Oliveira CE, Stamford TL, Gomes Neto NJ, de Souza EL. Inhibition of Staphylococcus aureus in broth and meat broth using synergies of phenolics and organic acids. Int J Food Microbiol. 2010;137:312-6.
    • (2010) Int J Food Microbiol , vol.137 , pp. 312-316
    • De Oliveira, C.E.1    Stamford, T.L.2    Gomes Neto, N.J.3    De Souza, E.L.4
  • 41
    • 84899585166 scopus 로고    scopus 로고
    • Suppressive drug interactions between antifungals
    • 24766845
    • de Vos MG, Bollenbach T. Suppressive drug interactions between antifungals. Chem Biol. 2014;21:439-40.
    • (2014) Chem Biol , vol.21 , pp. 439-440
    • De Vos, M.G.1    Bollenbach, T.2
  • 42
    • 84930678786 scopus 로고    scopus 로고
    • Counteraction of antibiotic production and degradation stabilizes microbial communities
    • 1:CAS:528:DC%2BC2MXht1WlurjN 25992546 4551410
    • Kelsic ED, Zhao J, Vetsigian K, Kishony R. Counteraction of antibiotic production and degradation stabilizes microbial communities. Nature. 2015;521:516-9.
    • (2015) Nature , vol.521 , pp. 516-519
    • Kelsic, E.D.1    Zhao, J.2    Vetsigian, K.3    Kishony, R.4
  • 43
    • 84962421663 scopus 로고    scopus 로고
    • Multi-locus genotypes underlying temperature sensitivity in a Mutationally induced trait
    • 26990313 4798298
    • Lee JT, Taylor MB, Shen A, Ehrenreich IM. Multi-locus genotypes underlying temperature sensitivity in a Mutationally induced trait. PLoS Genet. 2016;12:e1005929.
    • (2016) PLoS Genet , vol.12 , pp. e1005929
    • Lee, J.T.1    Taylor, M.B.2    Shen, A.3    Ehrenreich, I.M.4
  • 44
    • 0036139176 scopus 로고    scopus 로고
    • Bacteriophage therapy rescues mice bacteremic from a clinical isolate of vancomycin-resistant Enterococcus faecium
    • 1:CAS:528:DC%2BD3MXptlKht74%3D 11748184 127648
    • Biswas B, Adhya S, Washart P, Paul B, Trostel AN, Powell B, Carlton R, Merril CR. Bacteriophage therapy rescues mice bacteremic from a clinical isolate of vancomycin-resistant Enterococcus faecium. Infect Immun. 2002;70:204-10.
    • (2002) Infect Immun , vol.70 , pp. 204-210
    • Biswas, B.1    Adhya, S.2    Washart, P.3    Paul, B.4    Trostel, A.N.5    Powell, B.6    Carlton, R.7    Merril, C.R.8
  • 45
    • 0037379524 scopus 로고    scopus 로고
    • Use of genetically engineered phage to deliver antimicrobial agents to bacteria: an alternative therapy for treatment of bacterial infections
    • 1:CAS:528:DC%2BD3sXivVSnu7Y%3D 12654662 152521
    • Westwater C, Kasman LM, Schofield DA, Werner PA, Dolan JW, Schmidt MG, Norris JS. Use of genetically engineered phage to deliver antimicrobial agents to bacteria: an alternative therapy for treatment of bacterial infections. Antimicrob Agents Chemother. 2003;47:1301-7.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1301-1307
    • Westwater, C.1    Kasman, L.M.2    Schofield, D.A.3    Werner, P.A.4    Dolan, J.W.5    Schmidt, M.G.6    Norris, J.S.7
  • 46
    • 84855894994 scopus 로고    scopus 로고
    • Reversing bacterial resistance to antibiotics by phage-mediated delivery of dominant sensitive genes
    • 1:CAS:528:DC%2BC38XhsVOiur4%3D 22113912 3264097
    • Edgar R, Friedman N, Molshanski-Mor S, Qimron U. Reversing bacterial resistance to antibiotics by phage-mediated delivery of dominant sensitive genes. Appl Environ Microbiol. 2012;78:744-51.
    • (2012) Appl Environ Microbiol , vol.78 , pp. 744-751
    • Edgar, R.1    Friedman, N.2    Molshanski-Mor, S.3    Qimron, U.4
  • 47
    • 0036070576 scopus 로고    scopus 로고
    • Bacteriophage control of bacterial virulence
    • 1:CAS:528:DC%2BD38XlsFCms7Y%3D 12117903 128183
    • Wagner PL, Waldor MK. Bacteriophage control of bacterial virulence. Infect Immun. 2002;70:3985-93.
    • (2002) Infect Immun , vol.70 , pp. 3985-3993
    • Wagner, P.L.1    Waldor, M.K.2
  • 48
    • 0035933529 scopus 로고    scopus 로고
    • A protein antibiotic in the phage Qbeta virion: diversity in lysis targets
    • 1:CAS:528:DC%2BD3MXkslSht7g%3D 11423662
    • Bernhardt TG, Wang IN, Struck DK, Young R. A protein antibiotic in the phage Qbeta virion: diversity in lysis targets. Science. 2001;292:2326-9.
    • (2001) Science , vol.292 , pp. 2326-2329
    • Bernhardt, T.G.1    Wang, I.N.2    Struck, D.K.3    Young, R.4
  • 49
    • 84877048448 scopus 로고    scopus 로고
    • Predatory bacteria: a potential ally against multidrug-resistant gram-negative pathogens
    • 1:CAS:528:DC%2BC3sXnsVKgs78%3D 23650563 3641118
    • Kadouri DE, To K, Shanks RM, Doi Y. Predatory bacteria: a potential ally against multidrug-resistant gram-negative pathogens. PLoS ONE. 2013;8:e63397.
    • (2013) PLoS ONE , vol.8 , pp. e63397
    • Kadouri, D.E.1    To, K.2    Shanks, R.M.3    Doi, Y.4


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