-
1
-
-
0028044629
-
The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose
-
COI: 1:CAS:528:DyaK2cXitFensbs%3D, PID: 8282810
-
Kanai Y, Lee WS, You G, Brown D, Hediger MA. The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. J Clin Invest. 1994;93(1):397–404.
-
(1994)
J Clin Invest
, vol.93
, Issue.1
, pp. 397-404
-
-
Kanai, Y.1
Lee, W.S.2
You, G.3
Brown, D.4
Hediger, M.A.5
-
2
-
-
0034997336
-
Renal Na(+)-glucose cotransporters
-
COI: 1:CAS:528:DC%2BD3MXjtVyku7g%3D, PID: 11133510
-
Wright EM. Renal Na(+)-glucose cotransporters. American journal of physiology Renal physiology. 2001;280(1):F10–8.
-
(2001)
American journal of physiology Renal physiology.
, vol.280
, Issue.1
, pp. F10-F18
-
-
Wright, E.M.1
-
3
-
-
84923791994
-
Pharmacodynamics, efficacy and safety of sodium-glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC2cXitFSqurjI, PID: 25488697
-
Scheen AJ. Pharmacodynamics, efficacy and safety of sodium-glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus. Drugs. 2015;75(1):33–59.
-
(2015)
Drugs
, vol.75
, Issue.1
, pp. 33-59
-
-
Scheen, A.J.1
-
4
-
-
84960433486
-
SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: a systematic review and network meta-analysis
-
PID: 26911584
-
Shyangdan DS, Uthman OA, Waugh N. SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: a systematic review and network meta-analysis. BMJ Open. 2016;6(2):e009417.
-
(2016)
BMJ Open
, vol.6
, Issue.2
-
-
Shyangdan, D.S.1
Uthman, O.A.2
Waugh, N.3
-
5
-
-
84874291673
-
Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise
-
COI: 1:STN:280:DC%2BC3s3lvVWlsQ%3D%3D, PID: 23279307
-
Stenlof K, Cefalu WT, Kim KA, Alba M, Usiskin K, Tong C, et al. Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab. 2013;15(4):372–82.
-
(2013)
Diabetes Obes Metab
, vol.15
, Issue.4
, pp. 372-382
-
-
Stenlof, K.1
Cefalu, W.T.2
Kim, K.A.3
Alba, M.4
Usiskin, K.5
Tong, C.6
-
6
-
-
77956921439
-
Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial
-
PID: 20566676
-
Ferrannini E, Ramos SJ, Salsali A, Tang W, List JF. Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial. Diabetes Care. 2010;33(10):2217–24.
-
(2010)
Diabetes Care
, vol.33
, Issue.10
, pp. 2217-2224
-
-
Ferrannini, E.1
Ramos, S.J.2
Salsali, A.3
Tang, W.4
List, J.F.5
-
7
-
-
84903557735
-
Efficacy and safety of luseogliflozin as monotherapy in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, phase 3 study
-
COI: 1:CAS:528:DC%2BC2cXhtVyitLrN, PID: 24708292
-
Seino Y, Sasaki T, Fukatsu A, Ubukata M, Sakai S, Samukawa Y. Efficacy and safety of luseogliflozin as monotherapy in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, phase 3 study. Curr Med Res Opin. 2014;30(7):1245–55.
-
(2014)
Curr Med Res Opin
, vol.30
, Issue.7
, pp. 1245-1255
-
-
Seino, Y.1
Sasaki, T.2
Fukatsu, A.3
Ubukata, M.4
Sakai, S.5
Samukawa, Y.6
-
8
-
-
84880543926
-
Efficacy and safety of canagliflozin treatment in older subjects with type 2 diabetes mellitus: a randomized trial
-
PID: 23680739
-
Bode B, Stenlof K, Sullivan D, Fung A, Usiskin K. Efficacy and safety of canagliflozin treatment in older subjects with type 2 diabetes mellitus: a randomized trial. Hospital practice. 2013;41(2):72–84.
-
(2013)
Hospital practice
, vol.41
, Issue.2
, pp. 72-84
-
-
Bode, B.1
Stenlof, K.2
Sullivan, D.3
Fung, A.4
Usiskin, K.5
-
9
-
-
84914181817
-
Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise
-
COI: 1:CAS:528:DC%2BC2cXhslemtrfF, PID: 24909293
-
Kaku K, Kiyosue A, Inoue S, Ueda N, Tokudome T, Yang J, et al. Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise. Diabetes Obes Metab. 2014;16(11):1102–10.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.11
, pp. 1102-1110
-
-
Kaku, K.1
Kiyosue, A.2
Inoue, S.3
Ueda, N.4
Tokudome, T.5
Yang, J.6
-
10
-
-
84904207974
-
Efficacy and safety of canagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled with diet and exercise: a 24-week, randomized, double-blind, placebo-controlled, phase III study
-
COI: 1:CAS:528:DC%2BC2cXhtFelurbL, PID: 25010793
-
Inagaki N, Kondo K, Yoshinari T, Takahashi N, Susuta Y, Kuki H. Efficacy and safety of canagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled with diet and exercise: a 24-week, randomized, double-blind, placebo-controlled, phase III study. Expert Opin Pharmacother. 2014;15(11):1501–15.
-
(2014)
Expert Opin Pharmacother
, vol.15
, Issue.11
, pp. 1501-1515
-
-
Inagaki, N.1
Kondo, K.2
Yoshinari, T.3
Takahashi, N.4
Susuta, Y.5
Kuki, H.6
-
11
-
-
84975318811
-
Efficacy and safety of canagliflozin in combination with insulin: a double-blind, randomized, placebo-controlled study in Japanese patients with type 2 diabetes mellitus
-
PID: 27316668
-
Inagaki N, Harashima S, Maruyama N, Kawaguchi Y, Goda M, Iijima H. Efficacy and safety of canagliflozin in combination with insulin: a double-blind, randomized, placebo-controlled study in Japanese patients with type 2 diabetes mellitus. Cardiovasc Diabetol. 2016;15:89.
-
(2016)
Cardiovasc Diabetol
, vol.15
, pp. 89
-
-
Inagaki, N.1
Harashima, S.2
Maruyama, N.3
Kawaguchi, Y.4
Goda, M.5
Iijima, H.6
-
12
-
-
77953857048
-
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC3cXotVagtro%3D, PID: 20609968
-
Bailey CJ, Gross JL, Pieters A, Bastien A, List JF. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;375(9733):2223–33.
-
(2010)
Lancet
, vol.375
, Issue.9733
, pp. 2223-2233
-
-
Bailey, C.J.1
Gross, J.L.2
Pieters, A.3
Bastien, A.4
List, J.F.5
-
13
-
-
84901455931
-
Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial
-
PID: 24722494
-
Haring HU, Merker L, Seewaldt-Becker E, Weimer M, Meinicke T, Broedl UC, et al. Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care. 2014;37(6):1650–9.
-
(2014)
Diabetes Care
, vol.37
, Issue.6
, pp. 1650-1659
-
-
Haring, H.U.1
Merker, L.2
Seewaldt-Becker, E.3
Weimer, M.4
Meinicke, T.5
Broedl, U.C.6
-
14
-
-
84887997289
-
Efficacy and safety of canagliflozin compared with placebo and sitagliptin in patients with type 2 diabetes on background metformin monotherapy: a randomised trial
-
COI: 1:CAS:528:DC%2BC3sXhsVOntrvO, PID: 24026211
-
Lavalle-Gonzalez FJ, Januszewicz A, Davidson J, Tong C, Qiu R, Canovatchel W, et al. Efficacy and safety of canagliflozin compared with placebo and sitagliptin in patients with type 2 diabetes on background metformin monotherapy: a randomised trial. Diabetologia. 2013;56(12):2582–92.
-
(2013)
Diabetologia
, vol.56
, Issue.12
, pp. 2582-2592
-
-
Lavalle-Gonzalez, F.J.1
Januszewicz, A.2
Davidson, J.3
Tong, C.4
Qiu, R.5
Canovatchel, W.6
-
15
-
-
84858020943
-
Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
-
COI: 1:CAS:528:DC%2BC38Xkt1yms78%3D, PID: 22238392
-
Bolinder J, Ljunggren O, Kullberg J, Johansson L, Wilding J, Langkilde AM, et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab. 2012;97(3):1020–31.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, Issue.3
, pp. 1020-1031
-
-
Bolinder, J.1
Ljunggren, O.2
Kullberg, J.3
Johansson, L.4
Wilding, J.5
Langkilde, A.M.6
-
16
-
-
84922108911
-
Ipragliflozin in combination with metformin for the treatment of Japanese patients with type 2 diabetes: ILLUMINATE, a randomized, double-blind, placebo-controlled study
-
COI: 1:CAS:528:DC%2BC2MXitlKrur8%3D, PID: 24919820
-
Kashiwagi A, Kazuta K, Goto K, Yoshida S, Ueyama E, Utsuno A. Ipragliflozin in combination with metformin for the treatment of Japanese patients with type 2 diabetes: ILLUMINATE, a randomized, double-blind, placebo-controlled study. Diabetes Obes Metab. 2015;17(3):304–8.
-
(2015)
Diabetes Obes Metab
, vol.17
, Issue.3
, pp. 304-308
-
-
Kashiwagi, A.1
Kazuta, K.2
Goto, K.3
Yoshida, S.4
Ueyama, E.5
Utsuno, A.6
-
17
-
-
84892368256
-
Dapagliflozin as monotherapy in drug-naive Asian patients with type 2 diabetes mellitus: a randomized, blinded, prospective phase III study
-
COI: 1:CAS:528:DC%2BC2cXivVOmtw%3D%3D, PID: 24378206
-
Ji L, Ma J, Li H, Mansfield TA, T'Joen CL, Iqbal N, et al. Dapagliflozin as monotherapy in drug-naive Asian patients with type 2 diabetes mellitus: a randomized, blinded, prospective phase III study. Clin Ther. 2014;36(1):84–100 e9.
-
(2014)
Clin Ther
, vol.36
, Issue.1
, pp. 80-84
-
-
Ji, L.1
Ma, J.2
Li, H.3
Mansfield, T.A.4
T'Joen, C.L.5
Iqbal, N.6
-
18
-
-
84928196614
-
Empagliflozin reduces blood pressure in patients with type 2 diabetes and hypertension
-
COI: 1:CAS:528:DC%2BC2MXksFyktLo%3D, PID: 25271206
-
Tikkanen I, Narko K, Zeller C, Green A, Salsali A, Broedl UC, et al. Empagliflozin reduces blood pressure in patients with type 2 diabetes and hypertension. Diabetes Care. 2015;38(3):420–8.
-
(2015)
Diabetes Care
, vol.38
, Issue.3
, pp. 420-428
-
-
Tikkanen, I.1
Narko, K.2
Zeller, C.3
Green, A.4
Salsali, A.5
Broedl, U.C.6
-
19
-
-
84885954870
-
Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial
-
COI: 1:CAS:528:DC%2BC2cXosFSks7k%3D, PID: 24622369
-
Roden M, Weng J, Eilbracht J, Delafont B, Kim G, Woerle HJ, et al. Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet Diabetes Endocrinol. 2013;1(3):208–19.
-
(2013)
The Lancet Diabetes Endocrinol.
, vol.1
, Issue.3
, pp. 208-219
-
-
Roden, M.1
Weng, J.2
Eilbracht, J.3
Delafont, B.4
Kim, G.5
Woerle, H.J.6
-
20
-
-
84899558137
-
Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative study
-
PID: 24678906
-
Kaku K, Watada H, Iwamoto Y, Utsunomiya K, Terauchi Y, Tobe K, et al. Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative study. Cardiovasc Diabetol. 2014;13:65.
-
(2014)
Cardiovasc Diabetol
, vol.13
, pp. 65
-
-
Kaku, K.1
Watada, H.2
Iwamoto, Y.3
Utsunomiya, K.4
Terauchi, Y.5
Tobe, K.6
-
21
-
-
84953638180
-
Reductions in mean 24-hour ambulatory blood pressure after 6-week treatment with canagliflozin in patients with type 2 diabetes mellitus and hypertension
-
COI: 1:CAS:528:DC%2BC28XnsFeltw%3D%3D
-
Townsend RR, Machin I, Ren J, Trujillo A, Kawaguchi M, Vijapurkar U, et al. Reductions in mean 24-hour ambulatory blood pressure after 6-week treatment with canagliflozin in patients with type 2 diabetes mellitus and hypertension. J Clin Hypertens. 2016;18(1):43–52.
-
(2016)
J Clin Hypertens
, vol.18
, Issue.1
, pp. 43-52
-
-
Townsend, R.R.1
Machin, I.2
Ren, J.3
Trujillo, A.4
Kawaguchi, M.5
Vijapurkar, U.6
-
22
-
-
84882251091
-
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis
-
PID: 24026259
-
Vasilakou D, Karagiannis T, Athanasiadou E, Mainou M, Liakos A, Bekiari E, et al. Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis. Ann Intern Med. 2013;159(4):262–74.
-
(2013)
Ann Intern Med
, vol.159
, Issue.4
, pp. 262-274
-
-
Vasilakou, D.1
Karagiannis, T.2
Athanasiadou, E.3
Mainou, M.4
Liakos, A.5
Bekiari, E.6
-
23
-
-
84898854471
-
Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis
-
COI: 1:CAS:528:DC%2BC2cXjsVKrur8%3D, PID: 24602971, e9
-
Baker WL, Smyth LR, Riche DM, Bourret EM, Chamberlin KW, White WB. Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis. Journal of the American Society of Hypertension: JASH. 2014;8(4):262–75. e9
-
(2014)
Journal of the American Society of Hypertension: JASH
, vol.8
, Issue.4
, pp. 262-275
-
-
Baker, W.L.1
Smyth, L.R.2
Riche, D.M.3
Bourret, E.M.4
Chamberlin, K.W.5
White, W.B.6
-
24
-
-
84959460390
-
Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: a randomised, double-blind, placebo-controlled, phase 3 study
-
COI: 1:CAS:528:DC%2BC28XhtFCisbbE, PID: 26620248
-
Weber MA, Mansfield TA, Cain VA, Iqbal N, Parikh S, Ptaszynska A. Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: a randomised, double-blind, placebo-controlled, phase 3 study. The Lancet Diabetes Endocrinol. 2016;4(3):211–20.
-
(2016)
The Lancet Diabetes Endocrinol.
, vol.4
, Issue.3
, pp. 211-220
-
-
Weber, M.A.1
Mansfield, T.A.2
Cain, V.A.3
Iqbal, N.4
Parikh, S.5
Ptaszynska, A.6
-
25
-
-
84880850027
-
Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes
-
COI: 1:CAS:528:DC%2BC3sXhtFygsr%2FE, PID: 23668478
-
Lambers Heerspink HJ, de Zeeuw D, Wie L, Leslie B, List J. Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes. Diabetes Obes Metab. 2013;15(9):853–62.
-
(2013)
Diabetes Obes Metab
, vol.15
, Issue.9
, pp. 853-862
-
-
Lambers Heerspink, H.J.1
de Zeeuw, D.2
Wie, L.3
Leslie, B.4
List, J.5
-
26
-
-
84901472559
-
Effects of hydrochlorothiazide on the pharmacokinetics, pharmacodynamics, and tolerability of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in healthy participants
-
COI: 1:CAS:528:DC%2BC2cXmtVCqsbs%3D, PID: 24726680
-
Devineni D, Vaccaro N, Polidori D, Rusch S, Wajs E. Effects of hydrochlorothiazide on the pharmacokinetics, pharmacodynamics, and tolerability of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in healthy participants. Clin Ther. 2014;36(5):698–710.
-
(2014)
Clin Ther
, vol.36
, Issue.5
, pp. 698-710
-
-
Devineni, D.1
Vaccaro, N.2
Polidori, D.3
Rusch, S.4
Wajs, E.5
-
27
-
-
0022343299
-
Exchangeable sodium and renin in hypertensive diabetic patients with and without nephropathy
-
PID: 3908321
-
O'Hare JA, Ferriss JB, Brady D, Twomey B, O'Sullivan DJ. Exchangeable sodium and renin in hypertensive diabetic patients with and without nephropathy. Hypertension. 1985;7(6 Pt 2):II43–8.
-
(1985)
Hypertension
, vol.7
, Issue.6
, pp. II43-II48
-
-
O'Hare, J.A.1
Ferriss, J.B.2
Brady, D.3
Twomey, B.4
O'Sullivan, D.J.5
-
28
-
-
33644688031
-
Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
-
COI: 1:CAS:528:DC%2BD2MXht12gs7fK, PID: 16306358
-
Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, Brown J. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes. 2005;54(12):3427–34.
-
(2005)
Diabetes
, vol.54
, Issue.12
, pp. 3427-3434
-
-
Rahmoune, H.1
Thompson, P.W.2
Ward, J.M.3
Smith, C.D.4
Hong, G.5
Brown, J.6
-
29
-
-
0242525141
-
Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials
-
COI: 1:CAS:528:DC%2BD3sXosFCmtrc%3D, PID: 12975389
-
Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension. 2003;42(5):878–84.
-
(2003)
Hypertension
, vol.42
, Issue.5
, pp. 878-884
-
-
Neter, J.E.1
Stam, B.E.2
Kok, F.J.3
Grobbee, D.E.4
Geleijnse, J.M.5
-
30
-
-
84892959743
-
The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus
-
PID: 24475922
-
Cherney DZ, Perkins BA, Soleymanlou N, Har R, Fagan N, Johansen OE, et al. The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus. Cardiovasc Diabetol. 2014;13:28.
-
(2014)
Cardiovasc Diabetol
, vol.13
, pp. 28
-
-
Cherney, D.Z.1
Perkins, B.A.2
Soleymanlou, N.3
Har, R.4
Fagan, N.5
Johansen, O.E.6
-
31
-
-
8844285190
-
Autonomic nervous function, arterial stiffness and blood pressure in patients with type I diabetes mellitus and normal urinary albumin excretion
-
PID: 15175635
-
van Ittersum FJ, Schram MT, van der Heijden-Spek JJ, Van Bortel LM, Elte JW, Biemond P, et al. Autonomic nervous function, arterial stiffness and blood pressure in patients with type I diabetes mellitus and normal urinary albumin excretion. J Hum Hypertens. 2004;18(11):761–8.
-
(2004)
J Hum Hypertens
, vol.18
, Issue.11
, pp. 761-768
-
-
van Ittersum, F.J.1
Schram, M.T.2
van der Heijden-Spek, J.J.3
Van Bortel, L.M.4
Elte, J.W.5
Biemond, P.6
-
32
-
-
0344874201
-
Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BD2cXhtlGiu74%3D
-
Diraison F, Moulin P, Beylot M. Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease. Diabetes & metabolism. 2003;29(5):478–85.
-
(2003)
Diabetes & metabolism
, vol.29
, Issue.5
, pp. 478-485
-
-
Diraison, F.1
Moulin, P.2
Beylot, M.3
-
33
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BD2MXktFSktLk%3D, PID: 15864352
-
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest. 2005;115(5):1343–51.
-
(2005)
J Clin Invest
, vol.115
, Issue.5
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
34
-
-
80055020543
-
The effect of two energy-restricted diets, a low-fructose diet versus a moderate natural fructose diet, on weight loss and metabolic syndrome parameters: a randomized controlled trial
-
COI: 1:CAS:528:DC%2BC3MXhtlKjsLfL, PID: 21621801
-
Madero M, Arriaga JC, Jalal D, Rivard C, McFann K, Perez-Mendez O, et al. The effect of two energy-restricted diets, a low-fructose diet versus a moderate natural fructose diet, on weight loss and metabolic syndrome parameters: a randomized controlled trial. Metab Clin Exp. 2011;60(11):1551–9.
-
(2011)
Metab Clin Exp
, vol.60
, Issue.11
, pp. 1551-1559
-
-
Madero, M.1
Arriaga, J.C.2
Jalal, D.3
Rivard, C.4
McFann, K.5
Perez-Mendez, O.6
-
35
-
-
80052524011
-
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC3MXhtlCnsb3L, PID: 21672123
-
Strojek K, Yoon KH, Hruba V, Elze M, Langkilde AM, Parikh S. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial. Diabetes Obes Metab. 2011;13(10):928–38.
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.10
, pp. 928-938
-
-
Strojek, K.1
Yoon, K.H.2
Hruba, V.3
Elze, M.4
Langkilde, A.M.5
Parikh, S.6
-
36
-
-
84861079280
-
Effects of SGLT2 inhibitors on cardiovascular outcomes
-
PID: 22381403
-
Foote C, Perkovic V, Neal B. Effects of SGLT2 inhibitors on cardiovascular outcomes. Diab Vasc Dis Res. 2012;9(2):117–23.
-
(2012)
Diab Vasc Dis Res
, vol.9
, Issue.2
, pp. 117-123
-
-
Foote, C.1
Perkovic, V.2
Neal, B.3
-
37
-
-
84861781220
-
Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes
-
COI: 1:CAS:528:DC%2BC38Xps1Kit7k%3D, PID: 22492586
-
Rosenstock J, Aggarwal N, Polidori D, Zhao Y, Arbit D, Usiskin K, et al. Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes. Diabetes Care. 2012;35(6):1232–8.
-
(2012)
Diabetes Care
, vol.35
, Issue.6
, pp. 1232-1238
-
-
Rosenstock, J.1
Aggarwal, N.2
Polidori, D.3
Zhao, Y.4
Arbit, D.5
Usiskin, K.6
-
38
-
-
84882245160
-
Effects of dapagliflozin on cardiovascular risk factors
-
PID: 23748519
-
Ptaszynska A, Hardy E, Johnsson E, Parikh S, List J. Effects of dapagliflozin on cardiovascular risk factors. Postgrad Med. 2013;125(3):181–9.
-
(2013)
Postgrad Med
, vol.125
, Issue.3
, pp. 181-189
-
-
Ptaszynska, A.1
Hardy, E.2
Johnsson, E.3
Parikh, S.4
List, J.5
-
39
-
-
77956526215
-
Licensing drugs for diabetes
-
PID: 20819887
-
Lehman R, Yudkin JS, Krumholz H. Licensing drugs for diabetes. BMJ. 2010;341:c4805.
-
(2010)
BMJ
, vol.341
, pp. c4805
-
-
Lehman, R.1
Yudkin, J.S.2
Krumholz, H.3
-
40
-
-
84892479365
-
Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
-
COI: 1:CAS:528:DC%2BC2cXptFWhtw%3D%3D, PID: 23906445
-
Bolinder J, Ljunggren O, Johansson L, Wilding J, Langkilde AM, Sjostrom CD, et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Diabetes Obes Metab. 2014;16(2):159–69.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.2
, pp. 159-169
-
-
Bolinder, J.1
Ljunggren, O.2
Johansson, L.3
Wilding, J.4
Langkilde, A.M.5
Sjostrom, C.D.6
-
41
-
-
42149186337
-
Factors associated with percent change in visceral versus subcutaneous abdominal fat during weight loss: findings from a systematic review
-
COI: 1:STN:280:DC%2BD1c3ksVKrug%3D%3D
-
Chaston TB, Dixon JB. Factors associated with percent change in visceral versus subcutaneous abdominal fat during weight loss: findings from a systematic review. Int J Obes. 2008;32(4):619–28.
-
(2008)
Int J Obes
, vol.32
, Issue.4
, pp. 619-628
-
-
Chaston, T.B.1
Dixon, J.B.2
-
42
-
-
84925304127
-
Effect of weight loss on magnetic resonance imaging estimation of liver fat and volume in patients with nonalcoholic steatohepatitis
-
e1
-
Patel NS, Doycheva I, Peterson MR, Hooker J, Kisselva T, Schnabl B, et al. Effect of weight loss on magnetic resonance imaging estimation of liver fat and volume in patients with nonalcoholic steatohepatitis. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association. 2015;13(3):561–8. e1
-
(2015)
Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association
, vol.13
, Issue.3
, pp. 561-568
-
-
Patel, N.S.1
Doycheva, I.2
Peterson, M.R.3
Hooker, J.4
Kisselva, T.5
Schnabl, B.6
-
43
-
-
84934970451
-
Hepatic steatosis as a marker of metabolic dysfunction
-
COI: 1:CAS:528:DC%2BC2MXhvFSqtrjO, PID: 26102213
-
Fabbrini E, Magkos F. Hepatic steatosis as a marker of metabolic dysfunction. Nutrients. 2015;7(6):4995–5019.
-
(2015)
Nutrients
, vol.7
, Issue.6
, pp. 4995-5019
-
-
Fabbrini, E.1
Magkos, F.2
-
44
-
-
84923902007
-
Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats
-
COI: 1:CAS:528:DC%2BC2MXjt1artbs%3D, PID: 25701721
-
Hayashizaki-Someya Y, Kurosaki E, Takasu T, Mitori H, Yamazaki S, Koide K, et al. Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats. Eur J Pharmacol. 2015;754:19–24.
-
(2015)
Eur J Pharmacol
, vol.754
, pp. 19-24
-
-
Hayashizaki-Someya, Y.1
Kurosaki, E.2
Takasu, T.3
Mitori, H.4
Yamazaki, S.5
Koide, K.6
-
45
-
-
84953791948
-
The selective SGLT2 inhibitor ipragliflozin has a therapeutic effect on nonalcoholic steatohepatitis in mice
-
PID: 26731267
-
Honda Y, Imajo K, Kato T, Kessoku T, Ogawa Y, Tomeno W, et al. The selective SGLT2 inhibitor ipragliflozin has a therapeutic effect on nonalcoholic steatohepatitis in mice. PLoS One. 2016;11(1):e0146337.
-
(2016)
PLoS One
, vol.11
, Issue.1
-
-
Honda, Y.1
Imajo, K.2
Kato, T.3
Kessoku, T.4
Ogawa, Y.5
Tomeno, W.6
-
46
-
-
84987624200
-
The Na+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels
-
COI: 1:CAS:528:DC%2BC28XhslaqtrrI, PID: 27381369
-
Hawley SA, Ford RJ, Smith BK, Gowans GJ, Mancini SJ, Pitt RD, et al. The Na+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes. 2016;65(9):2784–94.
-
(2016)
Diabetes
, vol.65
, Issue.9
, pp. 2784-2794
-
-
Hawley, S.A.1
Ford, R.J.2
Smith, B.K.3
Gowans, G.J.4
Mancini, S.J.5
Pitt, R.D.6
-
47
-
-
84961615237
-
Ipragliflozin improves hepatic steatosis in obese mice and liver dysfunction in type 2 diabetic patients irrespective of body weight reduction
-
PID: 26977813
-
Komiya C, Tsuchiya K, Shiba K, Miyachi Y, Furuke S, Shimazu N, et al. Ipragliflozin improves hepatic steatosis in obese mice and liver dysfunction in type 2 diabetic patients irrespective of body weight reduction. PLoS One. 2016;11(3):e0151511.
-
(2016)
PLoS One
, vol.11
, Issue.3
-
-
Komiya, C.1
Tsuchiya, K.2
Shiba, K.3
Miyachi, Y.4
Furuke, S.5
Shimazu, N.6
-
48
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
COI: 1:CAS:528:DC%2BC28XntVSkurs%3D, PID: 26378978
-
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;373(22):2117–28.
-
(2015)
N Engl J Med
, vol.373
, Issue.22
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
Fitchett, D.4
Bluhmki, E.5
Hantel, S.6
-
49
-
-
84895484977
-
Dapagliflozin treatment for type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials
-
COI: 1:CAS:528:DC%2BC2cXjvVymurs%3D, PID: 24115369
-
Zhang M, Zhang L, Wu B, Song H, An Z, Li S. Dapagliflozin treatment for type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Diabetes Metab Res Rev. 2014;30(3):204–21.
-
(2014)
Diabetes Metab Res Rev
, vol.30
, Issue.3
, pp. 204-221
-
-
Zhang, M.1
Zhang, L.2
Wu, B.3
Song, H.4
An, Z.5
Li, S.6
-
50
-
-
84924677348
-
Effect of canagliflozin on serum uric acid in patients with type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC2MXktVems7w%3D, PID: 25600248
-
Davies MJ, Trujillo A, Vijapurkar U, Damaraju CV, Meininger G. Effect of canagliflozin on serum uric acid in patients with type 2 diabetes mellitus. Diabetes Obes Metab. 2015;17(4):426–9.
-
(2015)
Diabetes Obes Metab
, vol.17
, Issue.4
, pp. 426-429
-
-
Davies, M.J.1
Trujillo, A.2
Vijapurkar, U.3
Damaraju, C.V.4
Meininger, G.5
-
51
-
-
84908555003
-
SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria
-
COI: 1:CAS:528:DC%2BC2cXht1yks73J, PID: 25044127
-
Chino Y, Samukawa Y, Sakai S, Nakai Y, Yamaguchi J, Nakanishi T, et al. SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria. Biopharm Drug Dispos. 2014;35(7):391–404.
-
(2014)
Biopharm Drug Dispos
, vol.35
, Issue.7
, pp. 391-404
-
-
Chino, Y.1
Samukawa, Y.2
Sakai, S.3
Nakai, Y.4
Yamaguchi, J.5
Nakanishi, T.6
-
52
-
-
84920971105
-
Glycosuria-mediated urinary uric acid excretion in patients with uncomplicated type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC2MXis12rtrY%3D, PID: 25377916
-
Lytvyn Y, Skrtic M, Yang GK, Yip PM, Perkins BA, Cherney DZ. Glycosuria-mediated urinary uric acid excretion in patients with uncomplicated type 1 diabetes mellitus. American journal of physiology Renal physiology. 2015;308(2):F77–83.
-
(2015)
American journal of physiology Renal physiology.
, vol.308
, Issue.2
, pp. F77-F83
-
-
Lytvyn, Y.1
Skrtic, M.2
Yang, G.K.3
Yip, P.M.4
Perkins, B.A.5
Cherney, D.Z.6
-
53
-
-
69549084672
-
Solute carrier family 2, member 9 and uric acid homeostasis
-
COI: 1:CAS:528:DC%2BD1MXpsFygtrc%3D, PID: 19593129
-
Cheeseman C. Solute carrier family 2, member 9 and uric acid homeostasis. Curr Opin Nephrol Hypertens. 2009;18(5):428–32.
-
(2009)
Curr Opin Nephrol Hypertens
, vol.18
, Issue.5
, pp. 428-432
-
-
Cheeseman, C.1
-
54
-
-
84923448295
-
SGLT-2 inhibitors and cardiovascular risk: proposed pathways and review of ongoing outcome trials
-
COI: 1:CAS:528:DC%2BC2MXkt1SqsLY%3D, PID: 25589482
-
Inzucchi SE, Zinman B, Wanner C, Ferrari R, Fitchett D, Hantel S, et al. SGLT-2 inhibitors and cardiovascular risk: proposed pathways and review of ongoing outcome trials. Diab Vasc Dis Res. 2015;12(2):90–100.
-
(2015)
Diab Vasc Dis Res
, vol.12
, Issue.2
, pp. 90-100
-
-
Inzucchi, S.E.1
Zinman, B.2
Wanner, C.3
Ferrari, R.4
Fitchett, D.5
Hantel, S.6
-
55
-
-
77957254503
-
The novel sodium glucose transporter 2 inhibitor dapagliflozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats
-
COI: 1:CAS:528:DC%2BC3cXhsVymurjO, PID: 20880347
-
Macdonald FR, Peel JE, Jones HB, Mayers RM, Westgate L, Whaley JM, et al. The novel sodium glucose transporter 2 inhibitor dapagliflozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats. Diabetes Obes Metab. 2010;12(11):1004–12.
-
(2010)
Diabetes Obes Metab
, vol.12
, Issue.11
, pp. 1004-1012
-
-
Macdonald, F.R.1
Peel, J.E.2
Jones, H.B.3
Mayers, R.M.4
Westgate, L.5
Whaley, J.M.6
-
56
-
-
84997354438
-
Canagliflozin, a sodium glucose cotransporter 2 inhibitor, attenuates obesity-induced inflammation in the nodose ganglion, hypothalamus, and skeletal muscle of mice
-
Naznin F, Sakoda H, Okada T, Tsubouchi H, Waise TM, Arakawa K et al. Canagliflozin, a sodium glucose cotransporter 2 inhibitor, attenuates obesity-induced inflammation in the nodose ganglion, hypothalamus, and skeletal muscle of mice. Eur J Pharmacol. 2016.
-
(2016)
Eur J Pharmacol
-
-
Naznin, F.1
Sakoda, H.2
Okada, T.3
Tsubouchi, H.4
Waise, T.M.5
Arakawa, K.6
-
57
-
-
85019327829
-
The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE−/− mice fed a western diet
-
Han JH, Oh TJ, Lee G, Maeng HJ, Lee DH, Kim KM et al. The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE−/− mice fed a western diet. Diabetologia. 2016.
-
(2016)
Diabetologia
-
-
Han, J.H.1
Oh, T.J.2
Lee, G.3
Maeng, H.J.4
Lee, D.H.5
Kim, K.M.6
-
58
-
-
84959375542
-
SGLT2 inhibitors provide an effective therapeutic option for diabetes complicated with insulin antibodies
-
COI: 1:CAS:528:DC%2BC2sXjtVOiu7c%3D, PID: 26549210
-
Hayashi A, Takano K, Kawai S, Shichiri M. SGLT2 inhibitors provide an effective therapeutic option for diabetes complicated with insulin antibodies. Endocr J. 2016;63(2):187–91.
-
(2016)
Endocr J
, vol.63
, Issue.2
, pp. 187-191
-
-
Hayashi, A.1
Takano, K.2
Kawai, S.3
Shichiri, M.4
-
59
-
-
84964823083
-
Low-carbohydrate diet combined with SGLT2 inhibitor for refractory hyperglycemia caused by insulin antibodies
-
COI: 1:CAS:528:DC%2BC28XnsVWgtbs%3D, PID: 27321315
-
Shigeno R, Horie I, Ando T, Abiru N, Kawakami A. Low-carbohydrate diet combined with SGLT2 inhibitor for refractory hyperglycemia caused by insulin antibodies. Diabetes Res Clin Pract. 2016;116:43–5.
-
(2016)
Diabetes Res Clin Pract
, vol.116
, pp. 43-45
-
-
Shigeno, R.1
Horie, I.2
Ando, T.3
Abiru, N.4
Kawakami, A.5
-
60
-
-
79959487586
-
Temporal trends in the prevalence of diabetic kidney disease in the United States
-
COI: 1:CAS:528:DC%2BC3MXotVahsLw%3D, PID: 21693741
-
de Boer IH, Rue TC, Hall YN, Heagerty PJ, Weiss NS, Himmelfarb J. Temporal trends in the prevalence of diabetic kidney disease in the United States. JAMA. 2011;305(24):2532–9.
-
(2011)
JAMA
, vol.305
, Issue.24
, pp. 2532-2539
-
-
de Boer, I.H.1
Rue, T.C.2
Hall, Y.N.3
Heagerty, P.J.4
Weiss, N.S.5
Himmelfarb, J.6
-
61
-
-
84930465070
-
Standards of medical care in diabetes—2015: summary of revisions
-
38 Suppl:S4
-
Standards of medical care in diabetes—2015: summary of revisions. Diabetes Care. 2015;38 Suppl:S4.
-
(2015)
Diabetes Care
-
-
-
62
-
-
32444451549
-
Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes
-
COI: 1:CAS:528:DC%2BD28Xht1Sru70%3D, PID: 16453013
-
Remuzzi G, Benigni A, Remuzzi A. Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes. J Clin Invest. 2006;116(2):288–96.
-
(2006)
J Clin Invest
, vol.116
, Issue.2
, pp. 288-296
-
-
Remuzzi, G.1
Benigni, A.2
Remuzzi, A.3
-
63
-
-
84892588641
-
SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice
-
COI: 1:CAS:528:DC%2BC2cXitleit7Y%3D, PID: 24226524
-
Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, et al. SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. American journal of physiology Renal physiology. 2014;306(2):F194–204.
-
(2014)
American journal of physiology Renal physiology
, vol.306
, Issue.2
, pp. F194-F204
-
-
Vallon, V.1
Gerasimova, M.2
Rose, M.A.3
Masuda, T.4
Satriano, J.5
Mayoux, E.6
-
64
-
-
84903528312
-
Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice
-
PID: 24960177
-
Terami N, Ogawa D, Tachibana H, Hatanaka T, Wada J, Nakatsuka A, et al. Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice. PLoS One. 2014;9(6):e100777.
-
(2014)
PLoS One
, vol.9
, Issue.6
-
-
Terami, N.1
Ogawa, D.2
Tachibana, H.3
Hatanaka, T.4
Wada, J.5
Nakatsuka, A.6
-
65
-
-
84975153660
-
The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes
-
Cherney D, Lund SS, Perkins BA, Groop PH, Cooper ME, Kaspers S et al. The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes. Diabetologia 2016.
-
(2016)
Diabetologia
-
-
Cherney, D.1
Lund, S.S.2
Perkins, B.A.3
Groop, P.H.4
Cooper, M.E.5
Kaspers, S.6
-
66
-
-
84893214045
-
Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC2cXitFSqtLg%3D, PID: 24334175
-
Cherney DZ, Perkins BA, Soleymanlou N, Maione M, Lai V, Lee A, et al. Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation. 2014;129(5):587–97.
-
(2014)
Circulation
, vol.129
, Issue.5
, pp. 587-597
-
-
Cherney, D.Z.1
Perkins, B.A.2
Soleymanlou, N.3
Maione, M.4
Lai, V.5
Lee, A.6
-
67
-
-
84871213936
-
Renal hyperfiltration related to diabetes mellitus and obesity in human disease
-
PID: 22253940
-
Sasson AN, Cherney DZ. Renal hyperfiltration related to diabetes mellitus and obesity in human disease. World J Diabetes. 2012;3(1):1–6.
-
(2012)
World J Diabetes
, vol.3
, Issue.1
, pp. 1-6
-
-
Sasson, A.N.1
Cherney, D.Z.2
-
68
-
-
0031721708
-
Nitric oxide release as an essential mitigating step in tubuloglomerular feedback: observations during intrarenal nitric oxide clamp
-
COI: 1:CAS:528:DyaK1cXlvVagtLk%3D, PID: 9727367
-
Turkstra E, Braam B, Koomans HA. Nitric oxide release as an essential mitigating step in tubuloglomerular feedback: observations during intrarenal nitric oxide clamp. Journal of the American Society of Nephrology: JASN. 1998;9(9):1596–603.
-
(1998)
Journal of the American Society of Nephrology: JASN
, vol.9
, Issue.9
, pp. 1596-1603
-
-
Turkstra, E.1
Braam, B.2
Koomans, H.A.3
-
69
-
-
84866656037
-
Glomerular hyperfiltration and renal disease progression in type 2 diabetes
-
COI: 1:CAS:528:DC%2BC38Xhs1Gks7%2FJ, PID: 22773704
-
Ruggenenti P, Porrini EL, Gaspari F, Motterlini N, Cannata A, Carrara F, et al. Glomerular hyperfiltration and renal disease progression in type 2 diabetes. Diabetes Care. 2012;35(10):2061–8.
-
(2012)
Diabetes Care
, vol.35
, Issue.10
, pp. 2061-2068
-
-
Ruggenenti, P.1
Porrini, E.L.2
Gaspari, F.3
Motterlini, N.4
Cannata, A.5
Carrara, F.6
-
70
-
-
84878060305
-
Effects of a new SGLT2 inhibitor, luseogliflozin, on diabetic nephropathy in T2DN rats
-
COI: 1:CAS:528:DC%2BC3sXptlOgsL4%3D, PID: 23492941
-
Kojima N, Williams JM, Takahashi T, Miyata N, Roman RJ. Effects of a new SGLT2 inhibitor, luseogliflozin, on diabetic nephropathy in T2DN rats. J Pharmacol Exp Ther. 2013;345(3):464–72.
-
(2013)
J Pharmacol Exp Ther
, vol.345
, Issue.3
, pp. 464-472
-
-
Kojima, N.1
Williams, J.M.2
Takahashi, T.3
Miyata, N.4
Roman, R.J.5
-
71
-
-
1942422098
-
ACE2, a new regulator of the renin-angiotensin system
-
COI: 1:CAS:528:DC%2BD2cXjsVeguro%3D, PID: 15109615
-
Burrell LM, Johnston CI, Tikellis C, Cooper ME. ACE2, a new regulator of the renin-angiotensin system. Trends in endocrinology and metabolism: TEM. 2004;15(4):166–9.
-
(2004)
Trends in endocrinology and metabolism: TEM
, vol.15
, Issue.4
, pp. 166-169
-
-
Burrell, L.M.1
Johnston, C.I.2
Tikellis, C.3
Cooper, M.E.4
-
72
-
-
84962613532
-
Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
-
COI: 1:CAS:528:DC%2BC28Xhs1yisb3E, PID: 27009625
-
Wu JH, Foote C, Blomster J, Toyama T, Perkovic V, Sundstrom J, et al. Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: a systematic review and meta-analysis. The Lancet Diabetes Endocrinol. 2016;4(5):411–9.
-
(2016)
The Lancet Diabetes Endocrinol.
, vol.4
, Issue.5
, pp. 411-419
-
-
Wu, J.H.1
Foote, C.2
Blomster, J.3
Toyama, T.4
Perkovic, V.5
Sundstrom, J.6
-
73
-
-
84922257190
-
Heart failure: a cardiovascular outcome in diabetes that can no longer be ignored
-
COI: 1:CAS:528:DC%2BC2MXhsVamsbc%3D, PID: 24731668
-
McMurray JJ, Gerstein HC, Holman RR, Pfeffer MA. Heart failure: a cardiovascular outcome in diabetes that can no longer be ignored. The Lancet Diabetes Endocrinol. 2014;2(10):843–51.
-
(2014)
The Lancet Diabetes Endocrinol
, vol.2
, Issue.10
, pp. 843-851
-
-
McMurray, J.J.1
Gerstein, H.C.2
Holman, R.R.3
Pfeffer, M.A.4
-
74
-
-
84964799148
-
Dipeptidyl peptidase-4 inhibitors and heart failure: analysis of spontaneous reports submitted to the FDA adverse event reporting system
-
COI: 1:CAS:528:DC%2BC28XjtFOnurw%3D, PID: 27067162
-
Raschi E, Poluzzi E, Koci A, Antonazzo IC, Marchesini G, De Ponti F. Dipeptidyl peptidase-4 inhibitors and heart failure: analysis of spontaneous reports submitted to the FDA adverse event reporting system. Nutrition, metabolism, and cardiovascular diseases: NMCD. 2016;26(5):380–6.
-
(2016)
Nutrition, metabolism, and cardiovascular diseases: NMCD
, vol.26
, Issue.5
, pp. 380-386
-
-
Raschi, E.1
Poluzzi, E.2
Koci, A.3
Antonazzo, I.C.4
Marchesini, G.5
De Ponti, F.6
-
75
-
-
33646766401
-
Role of diuretics in the prevention of heart failure: the antihypertensive and lipid-lowering treatment to prevent heart attack trial
-
COI: 1:CAS:528:DC%2BD28XktVWhtLY%3D, PID: 16651474
-
Davis BR, Piller LB, Cutler JA, Furberg C, Dunn K, Franklin S, et al. Role of diuretics in the prevention of heart failure: the antihypertensive and lipid-lowering treatment to prevent heart attack trial. Circulation. 2006;113(18):2201–10.
-
(2006)
Circulation
, vol.113
, Issue.18
, pp. 2201-2210
-
-
Davis, B.R.1
Piller, L.B.2
Cutler, J.A.3
Furberg, C.4
Dunn, K.5
Franklin, S.6
-
76
-
-
84872532310
-
Association between glycated haemoglobin and the risk of congestive heart failure in diabetes mellitus: systematic review and meta-analysis
-
COI: 1:CAS:528:DC%2BC3sXhsVKrsLc%3D, PID: 23099356
-
Erqou S, Lee CT, Suffoletto M, Echouffo-Tcheugui JB, de Boer RA, van Melle JP, et al. Association between glycated haemoglobin and the risk of congestive heart failure in diabetes mellitus: systematic review and meta-analysis. Eur J Heart Fail. 2013;15(2):185–93.
-
(2013)
Eur J Heart Fail
, vol.15
, Issue.2
, pp. 185-193
-
-
Erqou, S.1
Lee, C.T.2
Suffoletto, M.3
Echouffo-Tcheugui, J.B.4
de Boer, R.A.5
van Melle, J.P.6
-
77
-
-
0032902850
-
The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years
-
COI: 1:STN:280:DyaK1M3ms1Crsw%3D%3D, PID: 10333939
-
Coutinho M, Gerstein HC, Wang Y, Yusuf S. The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care. 1999;22(2):233–40.
-
(1999)
Diabetes Care
, vol.22
, Issue.2
, pp. 233-240
-
-
Coutinho, M.1
Gerstein, H.C.2
Wang, Y.3
Yusuf, S.4
-
78
-
-
37349080234
-
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension
-
PID: 18071071
-
van Heerebeek L, Hamdani N, Handoko ML, Falcao-Pires I, Musters RJ, Kupreishvili K, et al. Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension. Circulation. 2008;117(1):43–51.
-
(2008)
Circulation
, vol.117
, Issue.1
, pp. 43-51
-
-
van Heerebeek, L.1
Hamdani, N.2
Handoko, M.L.3
Falcao-Pires, I.4
Musters, R.J.5
Kupreishvili, K.6
-
79
-
-
34347352169
-
Diabetic cardiomyopathy revisited
-
PID: 17592090
-
Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation. 2007;115(25):3213–23.
-
(2007)
Circulation
, vol.115
, Issue.25
, pp. 3213-3223
-
-
Boudina, S.1
Abel, E.D.2
-
80
-
-
84975698839
-
Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME(R) trial
-
PID: 26819227
-
Fitchett D, Zinman B, Wanner C, Lachin JM, Hantel S, Salsali A, et al. Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME(R) trial. Eur Heart J. 2016;37(19):1526–34.
-
(2016)
Eur Heart J
, vol.37
, Issue.19
, pp. 1526-1534
-
-
Fitchett, D.1
Zinman, B.2
Wanner, C.3
Lachin, J.M.4
Hantel, S.5
Salsali, A.6
-
81
-
-
84975840750
-
Can a shift in fuel energetics explain the beneficial cardiorenal outcomes in the EMPA-REG OUTCOME study?
-
PID: 27289124
-
Mudaliar S, Alloju S, Henry RR. Can a shift in fuel energetics explain the beneficial cardiorenal outcomes in the EMPA-REG OUTCOME study? A Unifying Hypothesis Diabetes care. 2016;39(7):1115–22.
-
(2016)
A Unifying Hypothesis Diabetes care
, vol.39
, Issue.7
, pp. 1115-1122
-
-
Mudaliar, S.1
Alloju, S.2
Henry, R.R.3
-
82
-
-
84975853831
-
CV protection in the EMPA-REG OUTCOME trial: a “thrifty substrate” hypothesis
-
PID: 27289126
-
Ferrannini E, Mark M, Mayoux E. CV protection in the EMPA-REG OUTCOME trial: a “thrifty substrate” hypothesis. Diabetes Care. 2016;39(7):1108–14.
-
(2016)
Diabetes Care
, vol.39
, Issue.7
, pp. 1108-1114
-
-
Ferrannini, E.1
Mark, M.2
Mayoux, E.3
-
83
-
-
85019333447
-
Os 05-04 Empagliflozin exerts cardio- and Nephro-protective effects in Cohen-Rosenthal diabetic hypertensive rats
-
PID: 27753929
-
Abassi Z, Leor J, Landa N, Younis F, Hollander K, Mayoux E, et al. Os 05-04 Empagliflozin exerts cardio- and Nephro-protective effects in Cohen-Rosenthal diabetic hypertensive rats. J Hypertens. 2016;34(Suppl 1):e58–9.
-
(2016)
J Hypertens
, vol.34
, pp. e58-e59
-
-
Abassi, Z.1
Leor, J.2
Landa, N.3
Younis, F.4
Hollander, K.5
Mayoux, E.6
-
84
-
-
84978252552
-
Research into the effect of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus (REFORM) trial rationale and design
-
PID: 27422625
-
Singh JS, Fathi A, Vickneson K, Mordi I, Mohan M, Houston JG, et al. Research into the effect of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus (REFORM) trial rationale and design. Cardiovasc Diabetol. 2016;15:97.
-
(2016)
Cardiovasc Diabetol
, vol.15
, pp. 97
-
-
Singh, J.S.1
Fathi, A.2
Vickneson, K.3
Mordi, I.4
Mohan, M.5
Houston, J.G.6
-
85
-
-
85019335367
-
Euglycemic diabetic ketoacidosis with elevated acetone in a patient taking a sodium-glucose cotransporter-2 (SGLT2) inhibitor
-
Andrews TJ, Cox RD, Parker C, Kolb J. Euglycemic diabetic ketoacidosis with elevated acetone in a patient taking a sodium-glucose cotransporter-2 (SGLT2) inhibitor. J Emerg Med. 2016.
-
(2016)
J Emerg Med
-
-
Andrews, T.J.1
Cox, R.D.2
Parker, C.3
Kolb, J.4
-
86
-
-
84974663153
-
Euglycemic diabetic ketoacidosis in a 27 year-old female patient with type-1-diabetes treated with sodium-glucose cotransporter-2 (SGLT2) inhibitor Canagliflozin
-
PID: 27375734
-
Bader N, Mirza L. Euglycemic diabetic ketoacidosis in a 27 year-old female patient with type-1-diabetes treated with sodium-glucose cotransporter-2 (SGLT2) inhibitor Canagliflozin. Pakistan journal of medical sciences. 2016;32(3):786–8.
-
(2016)
Pakistan journal of medical sciences
, vol.32
, Issue.3
, pp. 786-788
-
-
Bader, N.1
Mirza, L.2
-
87
-
-
84964334442
-
Safety and tolerability of empagliflozin in patients with type 2 diabetes
-
COI: 1:CAS:528:DC%2BC28XlsF2gtr0%3D, PID: 27085585
-
Kohler S, Salsali A, Hantel S, Kaspers S, Woerle HJ, Kim G, et al. Safety and tolerability of empagliflozin in patients with type 2 diabetes. Clin Ther. 2016;38(6):1299–313.
-
(2016)
Clin Ther
, vol.38
, Issue.6
, pp. 1299-1313
-
-
Kohler, S.1
Salsali, A.2
Hantel, S.3
Kaspers, S.4
Woerle, H.J.5
Kim, G.6
-
88
-
-
84945206560
-
Efficacy and safety of dapagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetes mellitus
-
PID: 26474563
-
Fioretto P, Giaccari A, Sesti G. Efficacy and safety of dapagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetes mellitus. Cardiovasc Diabetol. 2015;14:142.
-
(2015)
Cardiovasc Diabetol
, vol.14
, pp. 142
-
-
Fioretto, P.1
Giaccari, A.2
Sesti, G.3
|