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Volumn 9, Issue 2, 2017, Pages

Liposomal formulations in clinical use: An updated review

Author keywords

Clinical trials; Drug delivery; Liposome technology; Liposomes; Marketed products; Nanotechnology; Therapeutics

Indexed keywords

AMPHOTERICIN B; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DIERUCOYLPHOSPHATIDYLCHOLINE; DIMYRISTOYL PHOSPHATIDYLCHOLINE; DIMYRISTOYLPHOSPHATIDYLGLYCEROL; DIOLEOLY SN GLYCERO PHOPHOETHANOLAMINE; DIOLEOYLPHOSPHATIDYLCHOLINE; DIOLEOYLPHOSPHATIDYLSERINE; DIPALMITOYLPHOSPHATIDYLGLYCEROL; DISTEAROYL SN GLYCERO PHOSPHOETHANOLAMINE; DISTEAROYLPHOSPHATIDIC ACID; DISTEAROYLPHOSPHATIDYLCHOLINE; DOXORUBICIN; EGG PHOSPHATIDYLCHOLINE; FLUOROURACIL; FOLINIC ACID; HYDROGENATED SOY PHOSPHATIDYLCHOLINE; IRINOTECAN; LIPOSOME; MACROGOL; METHOXY POLYETHYLENE GLYCOL; MIFAMURTIDE; MORPHINE SULFATE; PALMITOYLOLEOYLPHOSPHATIDYLCHOLINE; PHOSPHOLIPID; SPHINGOMYELIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCRISTINE;

EID: 85018516576     PISSN: None     EISSN: 19994923     Source Type: Journal    
DOI: 10.3390/pharmaceutics9020012     Document Type: Review
Times cited : (1588)

References (154)
  • 1
    • 85012373035 scopus 로고
    • Diffusion of univalent ions across the lamellae of swollen phospholipids
    • Bangham, A.; Standish, M.M.; Watkins, J. Diffusion of univalent ions across the lamellae of swollen phospholipids. J. Mol. Biol. 1965, 13, 238–252.
    • (1965) J. Mol. Biol , vol.13 , pp. 238-252
    • Bangham, A.1    Standish, M.M.2    Watkins, J.3
  • 3
    • 84861669644 scopus 로고    scopus 로고
    • Doxil®—The first FDA-approved nano-drug: Lessons learned
    • Barenholz, Y.C. Doxil®—The first FDA-approved nano-drug: Lessons learned. J. Control. Release 2012, 160, 117–134.
    • (2012) J. Control. Release , vol.160 , pp. 117-134
    • Barenholz, Y.C.1
  • 4
    • 0037124473 scopus 로고    scopus 로고
    • Introduction and overview of peptide and protein pegylation
    • Veronese, F.M.; Harris, J.M. Introduction and overview of peptide and protein pegylation. Adv. Drug Deliv. Rev. 2002, 54, 453.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 453
    • Veronese, F.M.1    Harris, J.M.2
  • 6
    • 0033774172 scopus 로고    scopus 로고
    • Clinical pharmacology of encapsulated sustained-release cytarabine
    • Murry, D.J.; Blaney, S.M. Clinical pharmacology of encapsulated sustained-release cytarabine. Ann. Pharmacother. 2000, 34, 1173–1178.
    • (2000) Ann. Pharmacother. , vol.34 , pp. 1173-1178
    • Murry, D.J.1    Blaney, S.M.2
  • 7
    • 84856452267 scopus 로고    scopus 로고
    • Liposomal drug formulations in cancer therapy: 15 Years along the road
    • Slingerland, M.; Guchelaar, H.-J.; Gelderblom, H. Liposomal drug formulations in cancer therapy: 15 Years along the road. Drug Discov. Today 2012, 17, 160–166.
    • (2012) Drug Discov. Today , vol.17 , pp. 160-166
    • Slingerland, M.1    Guchelaar, H.-J.2    Gelderblom, H.3
  • 9
    • 0037681850 scopus 로고    scopus 로고
    • Pharmacokinetics of pegylated liposomal doxorubicin
    • Gabizon, A.; Shmeeda, H.; Barenholz, Y. Pharmacokinetics of pegylated liposomal doxorubicin. Clin. Pharmacokinet. 2003, 42, 419–436.
    • (2003) Clin. Pharmacokinet. , vol.42 , pp. 419-436
    • Gabizon, A.1    Shmeeda, H.2    Barenholz, Y.3
  • 10
    • 0035085192 scopus 로고    scopus 로고
    • Liposome application: Problems and prospects
    • Barenholz, Y. Liposome application: Problems and prospects. Curr. Opin. Colloid interface Sci. 2001, 6, 66–77.
    • (2001) Curr. Opin. Colloid Interface Sci. , vol.6 , pp. 66-77
    • Barenholz, Y.1
  • 11
    • 85018483716 scopus 로고
    • Efficient Loading and Controlled Release of Amphipathic Molecules
    • Barenholz, Y.; Haran, G. Efficient Loading and Controlled Release of Amphipathic Molecules. U.S. Patent No. 5, 316, 771, 31 May 1994.
    • (1994) U.S. Patent No. 5 , vol.316 , Issue.771 , pp. 31
    • Barenholz, Y.1    Haran, G.2
  • 12
    • 0026453662 scopus 로고
    • Gelation of liposome interior A novel method for drug encapsulation
    • Lasic, D.; Frederik, P.; Stuart, M.; Barenholz, Y.; McIntosh, T. Gelation of liposome interior A novel method for drug encapsulation. FEBS Lett. 1992, 312, 255–258.
    • (1992) FEBS Lett , vol.312 , pp. 255-258
    • Lasic, D.1    Frederik, P.2    Stuart, M.3    Barenholz, Y.4    McIntosh, T.5
  • 14
    • 0029360317 scopus 로고
    • Liposome circulation time and tumor targeting: Implications for cancer chemotherapy
    • Gabizon, A.A. Liposome circulation time and tumor targeting: Implications for cancer chemotherapy. Adv. Drug Deliv. Rev. 1995, 16, 285–294.
    • (1995) Adv. Drug Deliv. Rev. , vol.16 , pp. 285-294
    • Gabizon, A.A.1
  • 15
    • 0028349925 scopus 로고
    • Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
    • Gabizon, A.; Catane, R.; Uziely, B.; Kaufman, B.; Safra, T.; Cohen, R.; Martin, F.; Huang, A.; Barenholz, Y. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. 1994, 54, 987–992.
    • (1994) Cancer Res. , vol.54 , pp. 987-992
    • Gabizon, A.1    Catane, R.2    Uziely, B.3    Kaufman, B.4    Safra, T.5    Cohen, R.6    Martin, F.7    Huang, A.8    Barenholz, Y.9
  • 16
    • 34548321254 scopus 로고    scopus 로고
    • Cardiac safety of liposomal anthracyclines
    • Batist, G. Cardiac safety of liposomal anthracyclines. Cardiovasc. Toxicol. 2007, 7, 72–74.
    • (2007) Cardiovasc. Toxicol. , vol.7 , pp. 72-74
    • Batist, G.1
  • 17
    • 70449699140 scopus 로고    scopus 로고
    • Liposomal daunorubicin as treatment for Kaposi’s sarcoma
    • Petre, C.E.; Dittmer, D.P. Liposomal daunorubicin as treatment for Kaposi’s sarcoma. Int. J. Nanomed. 2007, 2, 277.
    • (2007) Int. J. Nanomed. , vol.2 , pp. 277
    • Petre, C.E.1    Dittmer, D.P.2
  • 18
    • 11144310022 scopus 로고    scopus 로고
    • Advantages of liposomal delivery systems for anthracyclines
    • Amsterdam, The Netherlands
    • Allen, T.M.; Martin, F.J. Advantages of liposomal delivery systems for anthracyclines. In Seminars in Oncology; Elsevier: Amsterdam, The Netherlands, 2004.
    • Seminars in Oncology; Elsevier , pp. 2004
    • Allen, T.M.1    Martin, F.J.2
  • 19
    • 0028204863 scopus 로고
    • Daunoxome® treatment of solid tumors: Preclinical and clinical investigations
    • Forssen, E.A.; Ross, M.E. Daunoxome® treatment of solid tumors: Preclinical and clinical investigations. J. Liposome Res. 1994, 4, 481–512.
    • (1994) J. Liposome Res , vol.4 , pp. 481-512
    • Forssen, E.A.1    Ross, M.E.2
  • 20
    • 0026718957 scopus 로고
    • Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors
    • Forssen, E.A.; Coulter, D.M.; Proffitt, R.T. Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors. Cancer Res. 1992, 52, 3255–3261.
    • (1992) Cancer Res , vol.52 , pp. 3255-3261
    • Forssen, E.A.1    Coulter, D.M.2    Proffitt, R.T.3
  • 22
    • 0034075437 scopus 로고    scopus 로고
    • The pharmacokinetics of liposomal encapsulated daunorubicin are not modified by HAART in patients with HIV-associated Kaposi’s sarcoma. Cancer Chemother
    • Fumagalli, L.; Zucchetti, M.; Parisi, I.; Viganò, M.G.; Zecca, B.; Careddu, A.; D’Incalci, M.; Lazzarin, A. The pharmacokinetics of liposomal encapsulated daunorubicin are not modified by HAART in patients with HIV-associated Kaposi’s sarcoma. Cancer Chemother. Pharmacol. 2000, 45, 495–501.
    • (2000) Pharmacol , vol.45 , pp. 495-501
    • Fumagalli, L.1    Zucchetti, M.2    Parisi, I.3    Viganò, M.G.4    Zecca, B.5    Careddu, A.6    D’Incalci, M.7    Lazzarin, A.8
  • 23
    • 0014975590 scopus 로고
    • The pharmacokinetics of daunomycin in man. Clin. Pharmacol
    • Alberts, D.S.; Bachur, N.R.; Holtzman, J.L. The pharmacokinetics of daunomycin in man. Clin. Pharmacol. Ther. 1971, 12, 96–104.
    • (1971) Ther , vol.12 , pp. 96-104
    • Alberts, D.S.1    Bachur, N.R.2    Holtzman, J.L.3
  • 24
    • 0029102696 scopus 로고
    • Pharmacokinetics of intralumbar DTC-101 for the treatment of leptomeningeal metastases
    • Chamberlain, M.C.; Kormanik, P.; Howell, S.B.; Kim, S. Pharmacokinetics of intralumbar DTC-101 for the treatment of leptomeningeal metastases. Arch. Neurol. 1995, 52, 912–917.
    • (1995) Arch. Neurol. , vol.52 , pp. 912-917
    • Chamberlain, M.C.1    Kormanik, P.2    Howell, S.B.3    Kim, S.4
  • 26
    • 0032711629 scopus 로고    scopus 로고
    • Randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors
    • Glantz, M.J.; Jaeckle, K.A.; Chamberlain, M.C.; Phuphanich, S.; Recht, L.; Swinnen, L.J.; Maria, B.; LaFollette, S.; Schumann, G.B.; Cole, B.F. A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors. Clin. Cancer Res. 1999, 5, 3394–3402.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3394-3402
    • Glantz, M.J.1    Jaeckle, K.A.2    Chamberlain, M.C.3    Phuphanich, S.4    Recht, L.5    Swinnen, L.J.6    Maria, B.7    Lafollette, S.8    Schumann, G.B.9    Cole, B.10
  • 27
    • 0024211341 scopus 로고
    • Analysis of the effect of liposome encapsulation on the vesicant properties, acute and cardiac toxicities, and antitumor efficacy of doxorubicin
    • Balazsovits, J.; Mayer, L.; Bally, M.; Cullis, P.; McDonell, M.; Ginsberg, R.; Falk, R. Analysis of the effect of liposome encapsulation on the vesicant properties, acute and cardiac toxicities, and antitumor efficacy of doxorubicin. Cancer Chemother. Pharmacol. 1989, 23, 81–86.
    • (1989) Cancer Chemother. Pharmacol. , vol.23 , pp. 81-86
    • Balazsovits, J.1    Mayer, L.2    Bally, M.3    Cullis, P.4    McDonell, M.5    Ginsberg, R.6    Falk, R.7
  • 28
    • 0027299669 scopus 로고
    • Preclinical toxicology study of liposome encapsulated doxorubicin (TLC D-99): Comparison with doxorubicin and empty liposomes in mice and dogs
    • Kanter, P.; Bullard, G.; Pilkiewicz, F.; Mayer, L.; Cullis, P.; Pavelic, Z. Preclinical toxicology study of liposome encapsulated doxorubicin (TLC D-99): Comparison with doxorubicin and empty liposomes in mice and dogs. In Vivo 1992, 7, 85–95.
    • (1992) In Vivo , vol.7 , pp. 85-95
    • Kanter, P.1    Bullard, G.2    Pilkiewicz, F.3    Mayer, L.4    Cullis, P.5    Pavelic, Z.6
  • 29
    • 0034835602 scopus 로고    scopus 로고
    • Liposomal anthracyclines for breast cancer
    • Amsterdam, The Netherlands
    • Sparano, J.A.; Winer, E.P. Liposomal anthracyclines for breast cancer. In Seminars in Oncology; Elsevier: Amsterdam, The Netherlands, 2001.
    • Seminars in Oncology; Elsevier , pp. 2001
    • Sparano, J.A.1    Winer, E.P.2
  • 31
    • 0030977633 scopus 로고    scopus 로고
    • Intratumor distribution of doxorubicin following iv administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes
    • Harasym, T.O.; Cullis, P.R.; Bally, M.B. Intratumor distribution of doxorubicin following iv administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes. Cancer Chemother. Pharmacol. 1997, 40, 309–317.
    • (1997) Cancer Chemother. Pharmacol. , vol.40 , pp. 309-317
    • Harasym, T.O.1    Cullis, P.R.2    Bally, M.B.3
  • 32
    • 0036142158 scopus 로고    scopus 로고
    • Liposome-encapsulated doxorubicin compared with conventional doxorubicin in a randomized multicenter trial as first-line therapy of metastatic breast carcinoma
    • Harris, L.; Batist, G.; Belt, R.; Rovira, D.; Navari, R.; Azarnia, N.; Welles, L.; Winer, E. Liposome-encapsulated doxorubicin compared with conventional doxorubicin in a randomized multicenter trial as first-line therapy of metastatic breast carcinoma. Cancer 2002, 94, 25–36.
    • (2002) Cancer , vol.94 , pp. 25-36
    • Harris, L.1    Batist, G.2    Belt, R.3    Rovira, D.4    Navari, R.5    Azarnia, N.6    Welles, L.7    Winer, E.8
  • 33
    • 0035282073 scopus 로고    scopus 로고
    • Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer
    • Batist, G.; Ramakrishnan, G.; Rao, C.S.; Chandrasekharan, A.; Gutheil, J.; Guthrie, T.; Shah, P.; Khojasteh, A.; Nair, M.K.; Hoelzer, K. Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer. J. Clin. Oncol. 2001, 19, 1444–1454.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 1444-1454
    • Batist, G.1    Ramakrishnan, G.2    Rao, C.S.3    Chandrasekharan, A.4    Gutheil, J.5    Guthrie, T.6    Shah, P.7    Khojasteh, A.8    Nair, M.K.9    Hoelzer, K.10
  • 36
    • 77954752953 scopus 로고    scopus 로고
    • Mifamurtide in osteosarcoma—A practical review
    • Anderson, P.; Tomaras, M.; McConnell, K. Mifamurtide in osteosarcoma—A practical review. Drugs Today 2010, 46, 327–337.
    • (2010) Drugs Today , vol.46 , pp. 327-337
    • Anderson, P.1    Tomaras, M.2    McConnell, K.3
  • 39
    • 0028855939 scopus 로고
    • Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models
    • Webb, M.; Harasym, T.; Masin, D.; Bally, M.; Mayer, L. Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models. Br. J. Cancer 1995, 72, 896.
    • (1995) Br. J. Cancer , vol.72 , pp. 896
    • Webb, M.1    Harasym, T.2    Masin, D.3    Bally, M.4    Mayer, L.5
  • 41
    • 0034893950 scopus 로고    scopus 로고
    • Liposomal and nonliposomal drug pharmacokinetics after administration of liposome-encapsulated vincristine and their contribution to drug tissue distribution properties
    • Krishna, R.; Webb, M.S.; Onge, G.S.; Mayer, L.D. Liposomal and nonliposomal drug pharmacokinetics after administration of liposome-encapsulated vincristine and their contribution to drug tissue distribution properties. J. Pharmacol. Exp. Ther. 2001, 298, 1206–1212.
    • (2001) J. Pharmacol. Exp. Ther , vol.298 , pp. 1206-1212
    • Krishna, R.1    Webb, M.S.2    Onge, G.S.3    Mayer, L.D.4
  • 42
    • 68149156436 scopus 로고    scopus 로고
    • Vincristine sulfate liposomes injection (Marqibo) in heavily pretreated patients with refractory aggressive non-Hodgkin lymphoma
    • Rodriguez, M.; Pytlik, R.; Kozak, T.; Chhanabhai, M.; Gascoyne, R.; Lu, B.; Deitcher, S.R.; Winter, J.N. Vincristine sulfate liposomes injection (Marqibo) in heavily pretreated patients with refractory aggressive non-Hodgkin lymphoma. Cancer 2009, 115, 3475–3482.
    • (2009) Cancer , vol.115 , pp. 3475-3482
    • Rodriguez, M.1    Pytlik, R.2    Kozak, T.3    Chhanabhai, M.4    Gascoyne, R.5    Lu, B.6    Deitcher, S.R.7    Winter, J.N.8
  • 43
    • 33645047575 scopus 로고    scopus 로고
    • Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy
    • Drummond, D.C.; Noble, C.O.; Guo, Z.; Hong, K.; Park, J.W.; Kirpotin, D.B. Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy. Cancer Res. 2006, 66, 3271–3277.
    • (2006) Cancer Res , vol.66 , pp. 3271-3277
    • Drummond, D.C.1    Noble, C.O.2    Guo, Z.3    Hong, K.4    Park, J.W.5    Kirpotin, D.B.6
  • 44
    • 85018506474 scopus 로고    scopus 로고
    • Liposomes Useful for Drug Delivery. U.S. Patent No
    • Hong, K.; Drummond, D.C.; Kirpotin, D. Liposomes Useful for Drug Delivery. U.S. Patent No. US20160030341 A1, 4 February 2016.
    • (2016) US20160030341 , vol.A1 , pp. 4
    • Hong, K.1    Drummond, D.C.2    Kirpotin, D.3
  • 45
    • 84959459386 scopus 로고    scopus 로고
    • Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): A global, randomised, open-label, phase 3 trial
    • Wang-Gillam, A.; Li, C.-P.; Bodoky, G.; Dean, A.; Shan, Y.-S.; Jameson, G.; Macarulla, T.; Lee, K.-H.; Cunningham, D.; Blanc, J.F. Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): A global, randomised, open-label, phase 3 trial. Lancet 2016, 387, 545–557.
    • (2016) Lancet , vol.387 , pp. 545-557
    • Wang-Gillam, A.1    Li, C.-P.2    Bodoky, G.3    Dean, A.4    Shan, Y.-S.5    Jameson, G.6    Macarulla, T.7    Lee, K.-H.8    Cunningham, D.9    Blanc, J.F.10
  • 46
    • 0029899877 scopus 로고    scopus 로고
    • Amphotericin B lipid complex (Abelcet®) in the treatment of invasive mycoses: The North American experience
    • Lister, J. Amphotericin B lipid complex (Abelcet®) in the treatment of invasive mycoses: The North American experience. Eur. J. Haematol. 1996, 56, 18–23.
    • (1996) Eur. J. Haematol. , vol.56 , pp. 18-23
    • Lister, J.1
  • 47
    • 0025181867 scopus 로고
    • Incorporation of amphotericin B into large unilamellar vesicles composed of phosphatidylcholine and phosphatidylglycerol
    • Madden, T.; Janoff, A.; Cullis, P. Incorporation of amphotericin B into large unilamellar vesicles composed of phosphatidylcholine and phosphatidylglycerol. Chem. Phys. Lipids 1990, 52, 189–198.
    • (1990) Chem. Phys. Lipids , vol.52 , pp. 189-198
    • Madden, T.1    Janoff, A.2    Cullis, P.3
  • 49
  • 50
    • 0027140491 scopus 로고
    • Lipid complex (ABLC™): A molecular rationale for the attenuation of amphotericin B related toxicities
    • Janoff, A.; Perkins, W.; Saletan, S.; Swenson, C. Amphotericin B lipid complex (ABLC™): A molecular rationale for the attenuation of amphotericin B related toxicities. J. Liposome Res. 1993, 3, 451–471.
    • (1993) J. Liposome Res , vol.3 , pp. 451-471
    • Janoff, A.1    Perkins, W.2    Saletan, S.3    Swenson, C.4    Amphotericin, B.5
  • 52
    • 0027139351 scopus 로고
    • Development, characterization, efficacy and mode of action of AmBisome, a unilamellar liposomal formulation of amphotericin B
    • Adler-Moore, J.P.; Proffitt, R.T. Development, characterization, efficacy and mode of action of AmBisome, a unilamellar liposomal formulation of amphotericin B. J. Liposome Res. 1993, 3, 429–450.
    • (1993) J. Liposome Res. , vol.3 , pp. 429-450
    • Adler-Moore, J.P.1    Proffitt, R.T.2
  • 55
    • 0031904301 scopus 로고    scopus 로고
    • AmBisome (Liposomal amphotericin B): A comparative review
    • Boswell, G.; Buell, D.; Bekersky, I. AmBisome (liposomal amphotericin B): A comparative review. J. Clin. Pharmacol. 1998, 38, 583–592.
    • (1998) J. Clin. Pharmacol , vol.38 , pp. 583-592
    • Boswell, G.1    Buell, D.2    Bekersky, I.3
  • 56
    • 0025773798 scopus 로고
    • Novel antifungal drug delivery: Stable amphotericin B-cholesteryl sulfate discs
    • Guo, L.S.; Fielding, R.M.; Lasic, D.D.; Hamilton, R.L.; Mufson, D. Novel antifungal drug delivery: Stable amphotericin B-cholesteryl sulfate discs. Int. J. Pharm. 1991, 75, 45–54.
    • (1991) Int. J. Pharm. , vol.75 , pp. 45-54
    • Guo, L.S.1    Fielding, R.M.2    Lasic, D.D.3    Hamilton, R.L.4    Mufson, D.5
  • 57
    • 0026595038 scopus 로고
    • Relationship of pharmacokinetics and drug distribution in tissue to increased safety of amphotericin B colloidal dispersion in dogs
    • Fielding, R.; Singer, A.; Wang, L.; Babbar, S.; Guo, L. Relationship of pharmacokinetics and drug distribution in tissue to increased safety of amphotericin B colloidal dispersion in dogs. Antimicrob. Agents Chemother. 1992, 36, 299–307.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 299-307
    • Fielding, R.1    Singer, A.2    Wang, L.3    Babbar, S.4    Guo, L.5
  • 58
    • 0028932001 scopus 로고
    • Comparative tissue distribution and elimination of amphotericin B colloidal dispersion (Amphocil®) and Fungizone® after repeated dosing in rats. Pharm
    • Wang, L.H.; Fielding, R.M.; Smith, P.C.; Guo, L.S. Comparative tissue distribution and elimination of amphotericin B colloidal dispersion (Amphocil®) and Fungizone® after repeated dosing in rats. Pharm. Res. 1995, 12, 275–283.
    • (1995) Res , vol.12 , pp. 275-283
    • Wang, L.H.1    Fielding, R.M.2    Smith, P.C.3    Guo, L.S.4
  • 59
    • 0025845362 scopus 로고
    • Single-dose pharmacokinetics and tolerance of a cholesteryl sulfate complex of amphotericin B administered to healthy volunteers
    • Sanders, S.W.; Buchi, K.; Goddard, M.; Lang, J.; Tolman, K. Single-dose pharmacokinetics and tolerance of a cholesteryl sulfate complex of amphotericin B administered to healthy volunteers. Antimicrob. Agents Chemother. 1991, 35, 1029–1034.
    • (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 1029-1034
    • Sanders, S.W.1    Buchi, K.2    Goddard, M.3    Lang, J.4    Tolman, K.5
  • 61
    • 0029899107 scopus 로고    scopus 로고
    • Phase I study of amphotericin B colloidal dispersion for the treatment of invasive fungal infections after marrow transplant
    • Bowden, R.A.; Cays, M.; Gooley, T.; Mamelok, R.D.; van Burik, J.-A. Phase I study of amphotericin B colloidal dispersion for the treatment of invasive fungal infections after marrow transplant. J. Infect. Dis. 1996, 173, 1208–1215.
    • (1996) J. Infect. Dis , vol.173 , pp. 1208-1215
    • Bowden, R.A.1    Cays, M.2    Gooley, T.3    Mamelok, R.D.4    Van Burik, J.-A.5
  • 62
    • 85018520760 scopus 로고    scopus 로고
    • Vision through Photodynamic Therapy of the Eye. U.S. Patent No
    • Strong, H.A.; Levy, J.; Huber, G.; Fsadni, M. Vision through Photodynamic Therapy of the Eye. U.S. Patent No. US5910510 A, 8 June 1999.
    • (1999) US5910510 A , pp. 8
    • Strong, H.A.1    Levy, J.2    Huber, G.3    Fsadni, M.4
  • 63
    • 0027619793 scopus 로고
    • Liposomal delivery of a photosensitizer, benzoporphyrin derivative monoacid ring A (BPD), to tumor tissue in a mouse tumor model
    • Richter, A.M.; Waterfield, E.; Jain, A.K.; Canaan, A.J.; Allison, B.A.; Levy, J.G. Liposomal delivery of a photosensitizer, benzoporphyrin derivative monoacid ring A (BPD), to tumor tissue in a mouse tumor model. Photochem. Photobiol. 1993, 57, 1000–1006.
    • (1993) Photochem. Photobiol. , vol.57 , pp. 1000-1006
    • Richter, A.M.1    Waterfield, E.2    Jain, A.K.3    Canaan, A.J.4    Allison, B.A.5    Levy, J.G.6
  • 64
    • 0342632445 scopus 로고    scopus 로고
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of 2 randomized clinical trials—TAP report 1
    • Bressler, N.M. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of 2 randomized clinical trials—TAP report 1. Arch. Ophthalmol. 1999, 117, 1329–1345.
    • (1999) Arch. Ophthalmol. , vol.117 , pp. 1329-1345
    • Bressler, N.M.1
  • 65
    • 29144441223 scopus 로고    scopus 로고
    • Extended-Release Epidural Morphine (DepoDur™): An Old Drug with a New Profile
    • Alam, M.; Hartrick, C.T. Extended-Release Epidural Morphine (DepoDur™): An Old Drug with a New Profile. Pain Pract. 2005, 5, 349–353.
    • (2005) Pain Pract , vol.5 , pp. 349-353
    • Alam, M.1    Hartrick, C.T.2
  • 66
    • 27144433715 scopus 로고    scopus 로고
    • Sustained-Release Epidural Morphine (DepoDur™): A Review. Todays Ther
    • Hartrick, C.; Manvelian, G. Sustained-Release Epidural Morphine (DepoDur™): A Review. Todays Ther. Trends 2004, 22, 167–180.
    • (2004) Trends , vol.22 , pp. 167-180
    • Hartrick, C.1    Manvelian, G.2
  • 67
    • 0029790071 scopus 로고    scopus 로고
    • Sustained-release morphine for epidural analgesia in rats
    • Kim, T.; Murdande, S.; Gruber, A.; Kim, S. Sustained-release morphine for epidural analgesia in rats. J. Am. Soc. Anesthesiol. 1996, 85, 331–338.
    • (1996) J. Am. Soc. Anesthesiol , vol.85 , pp. 331-338
    • Kim, T.1    Murdande, S.2    Gruber, A.3    Kim, S.4
  • 68
    • 33748923981 scopus 로고    scopus 로고
    • Single-dose extended-release epidural morphine for pain following hip arthroplasty
    • Viscusi, E.R.; Kopacz, D.; Hartrick, C.; Martin, G.; Manvelian, G. Single-dose extended-release epidural morphine for pain following hip arthroplasty. Am. J. Ther. 2006, 13, 423–431.
    • (2006) Am. J. Ther , vol.13 , pp. 423-431
    • Viscusi, E.R.1    Kopacz, D.2    Hartrick, C.3    Martin, G.4    Manvelian, G.5
  • 69
    • 33845430694 scopus 로고    scopus 로고
    • Pharmacology of drugs formulated with DepoFoam™. Clin
    • Angst, M.S.; Drover, D.R. Pharmacology of drugs formulated with DepoFoam™. Clin. Pharmacokinet. 2006, 45, 1153–1176.
    • (2006) Pharmacokinet , vol.45 , pp. 1153-1176
    • Angst, M.S.1    Drover, D.R.2
  • 71
    • 77950991933 scopus 로고    scopus 로고
    • High-dose bupivacaine remotely loaded into multivesicular liposomes demonstrates slow drug release without systemic toxic plasma concentrations after subcutaneous administration in humans
    • Davidson, E.M.; Barenholz, Y.; Cohen, R.; Haroutiunian, S.; Kagan, L.; Ginosar, Y. High-dose bupivacaine remotely loaded into multivesicular liposomes demonstrates slow drug release without systemic toxic plasma concentrations after subcutaneous administration in humans. Anesth. Analg. 2010, 110, 1018–1023.
    • (2010) Anesth. Analg. , vol.110 , pp. 1018-1023
    • Davidson, E.M.1    Barenholz, Y.2    Cohen, R.3    Haroutiunian, S.4    Kagan, L.5    Ginosar, Y.6
  • 74
    • 84965021006 scopus 로고    scopus 로고
    • Pharmaceutical liposomal drug delivery: A review of new delivery systems and a look at the regulatory landscape
    • Zylberberg, C.; Matosevic, S. Pharmaceutical liposomal drug delivery: A review of new delivery systems and a look at the regulatory landscape. Drug Deliv. 2016, 23, 1–11.
    • (2016) Drug Deliv , vol.23 , pp. 1-11
    • Zylberberg, C.1    Matosevic, S.2
  • 77
    • 0141501161 scopus 로고    scopus 로고
    • Efficacy of virosome hepatitis A vaccine in young children in Nicaragua: Randomized placebo-controlled trial
    • Perez, O.M.; Herzog, C.; Zellmeyer, M.; Loáisiga, A.; Frösner, G.; Egger, M. Efficacy of virosome hepatitis A vaccine in young children in Nicaragua: Randomized placebo-controlled trial. J. Infect. Dis. 2003, 188, 671–677.
    • (2003) J. Infect. Dis , vol.188 , pp. 671-677
    • Perez, O.M.1    Herzog, C.2    Zellmeyer, M.3    Loáisiga, A.4    Frösner, G.5    Egger, M.6
  • 78
    • 0036883562 scopus 로고    scopus 로고
    • Long-term immunogenicity of an inactivated virosome hepatitis A vaccine
    • Bovier, P.; Bock, J.; Loutan, L.; Farinelli, T.; Glueck, R.; Herzog, C. Long-term immunogenicity of an inactivated virosome hepatitis A vaccine. J. Med. Virol. 2002, 68, 489–493.
    • (2002) J. Med. Virol , vol.68 , pp. 489-493
    • Bovier, P.1    Bock, J.2    Loutan, L.3    Farinelli, T.4    Glueck, R.5    Herzog, C.6
  • 79
    • 0037146938 scopus 로고    scopus 로고
    • New technology platforms in the development of vaccines for the future
    • Gluck, R.; Metcalfe, I. New technology platforms in the development of vaccines for the future. Vaccine 2002, 20, 10–16.
    • (2002) Vaccine , vol.20 , pp. 10-16
    • Gluck, R.1    Metcalfe, I.2
  • 80
    • 0028244249 scopus 로고
    • Immunogenicity of new virosome influenza vaccine in elderly people
    • Gluck, R.; Mischler, R.; Finkel, B.; Que, J.; Cryz, S.; Scarpa, B. Immunogenicity of new virosome influenza vaccine in elderly people. Lancet 1994, 344, 160–163.
    • (1994) Lancet , vol.344 , pp. 160-163
    • Gluck, R.1    Mischler, R.2    Finkel, B.3    Que, J.4    Cryz, S.5    Scarpa, B.6
  • 81
    • 0030812765 scopus 로고    scopus 로고
    • Immunogenicity of trivalent subunit versus virosome-formulated influenza vaccines in geriatric patients
    • Conne, P.; Gauthey, L.; Vernet, P.; Althaus, B.; Que, J.U.; Finkel, B.; Glück, R.; Cryz, S.J. Immunogenicity of trivalent subunit versus virosome-formulated influenza vaccines in geriatric patients. Vaccine 1997, 15, 1675–1679.
    • (1997) Vaccine , vol.15 , pp. 1675-1679
    • Conne, P.1    Gauthey, L.2    Vernet, P.3    Althaus, B.4    Que, J.U.5    Finkel, B.6    Glück, R.7    Cryz, S.J.8
  • 83
    • 70349775657 scopus 로고    scopus 로고
    • Clinical trials of lipid-associated aerosolized amikacin: The arikace™ story
    • Wiley-Liss Div JohnWiley & Sons Inc.: Hoboken, NJ, USA
    • Clancy, J.P. Clinical trials of lipid-associated aerosolized amikacin: The arikace™ story. In Pediatric Pulmonology; Wiley-Liss Div JohnWiley & Sons Inc.: Hoboken, NJ, USA, 2009.
    • In Pediatric Pulmonology , pp. 2009
    • Clancy, J.P.1
  • 84
    • 84896713591 scopus 로고    scopus 로고
    • Phase 3 efficacy and safety data from randomized, multicenter study of liposomal amikacin for inhalation (ARIKACE) Compared with TOBI in cystic fibrosis patients with chronic infection due to Pseudomonas Aeruginosa
    • Bilton, D.; Pressler, T.; Fajac, I.; Clancy, J.P.; Sands, D.; Minic, P.; Cipolli, M.; LaRosa, M.; Galeva, I.; Sole, A.A. Phase 3 efficacy and safety data from randomized, multicenter study of liposomal amikacin for inhalation (ARIKACE) Compared with TOBI in cystic fibrosis patients with chronic infection due to Pseudomonas Aeruginosa. Pediatr. Pulmonol. 2013, 48, 207–453.
    • (2013) Pediatr. Pulmonol. , vol.48 , pp. 207-453
    • Bilton, D.1    Pressler, T.2    Fajac, I.3    Clancy, J.P.4    Sands, D.5    Minic, P.6    Cipolli, M.7    Larosa, M.8    Galeva, I.9    Sole, A.A.10
  • 88
    • 84883461036 scopus 로고    scopus 로고
    • Victories and deceptions in tumor immunology: Stimuvax®
    • Kroemer, G.; Zitvogel, L.; Galluzzi, L. Victories and deceptions in tumor immunology: Stimuvax®. Oncoimmunology 2013, 2, e23687.
    • (2013) Oncoimmunology , vol.2
    • Kroemer, G.1    Zitvogel, L.2    Galluzzi, L.3
  • 92
    • 46749097976 scopus 로고    scopus 로고
    • Repairing DNA damage in xeroderma pigmentosum: T4N5 lotion and gene therapy
    • Zahid, S.; Brownell, I. Repairing DNA damage in xeroderma pigmentosum: T4N5 lotion and gene therapy. J. Drugs Dermatol. 2008, 7, 405–408.
    • (2008) J. Drugs Dermatol. , vol.7 , pp. 405-408
    • Zahid, S.1    Brownell, I.2
  • 93
    • 0025845451 scopus 로고
    • Enhanced unscheduled DNA synthesis in UV-irradiated human skin explants treated with T4N5 liposomes
    • Yarosh, D.B.; Kibitel, J.T.; Green, L.A.; Spinowitz, A. Enhanced unscheduled DNA synthesis in UV-irradiated human skin explants treated with T4N5 liposomes. J. Investig. Dermatol. 1991, 97, 147–150.
    • (1991) J. Investig. Dermatol. , vol.97 , pp. 147-150
    • Yarosh, D.B.1    Kibitel, J.T.2    Green, L.A.3    Spinowitz, A.4
  • 94
    • 0034128674 scopus 로고    scopus 로고
    • Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factory
    • Wolf, P.; Müllegger, R.R.; Soyer, H.P.; Hofer, A.; Smolle, J.; Horn, M.; Cerroni, L.; Hofmann-Wellenhof, R.; Kerl, H.; Maier, H. Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factory. J. Investig. Dermatol. 2000, 114, 149–156.
    • (2000) J. Investig. Dermatol. , vol.114 , pp. 149-156
    • Wolf, P.1    Müllegger, R.R.2    Soyer, H.P.3    Hofer, A.4    Smolle, J.5    Horn, M.6    Cerroni, L.7    Hofmann-Wellenhof, R.8    Kerl, H.9    Maier, H.10
  • 95
    • 45549096212 scopus 로고    scopus 로고
    • T4 endonuclease V: Review and application to dermatology
    • Cafardi, J.A.; Elmets, C.A. T4 endonuclease V: Review and application to dermatology. Expert Opin. Biol. Ther. 2008, 8, 829–838.
    • (2008) Expert Opin. Biol. Ther. , vol.8 , pp. 829-838
    • Cafardi, J.A.1    Elmets, C.A.2
  • 96
    • 84856638259 scopus 로고    scopus 로고
    • Clinical development of liposome-based drugs: Formulation, characterization, and therapeutic efficacy
    • Chang, H.-I.; Yeh, M.-K. Clinical development of liposome-based drugs: Formulation, characterization, and therapeutic efficacy. Int. J. Nanomed. 2012, 7, 49–60.
    • (2012) Int. J. Nanomed , vol.7 , pp. 49-60
    • Chang, H.-I.1    Yeh, M.-K.2
  • 97
  • 98
    • 84876583174 scopus 로고    scopus 로고
    • Therapeutic effect of liposomal prostaglandin E1 in acute lower limb ischemia as an adjuvant to hybrid procedures
    • Li, J.; Wang, B.; Wang, Y.; Wu, F.; Li, P.; Li, Y.; Zhao, L.; Cui, W.; Ding, Y.; An, Q. Therapeutic effect of liposomal prostaglandin E1 in acute lower limb ischemia as an adjuvant to hybrid procedures. Exp. Ther. Med. 2013, 5, 1760–1764.
    • (2013) Exp. Ther. Med. , vol.5 , pp. 1760-1764
    • Li, J.1    Wang, B.2    Wang, Y.3    Wu, F.4    Li, P.5    Li, Y.6    Zhao, L.7    Cui, W.8    Ding, Y.9    An, Q.10
  • 99
    • 84907193975 scopus 로고    scopus 로고
    • Thermosensitive liposomes with higher phase transition temperature for targeted drug delivery to tumor
    • Chen, J.; He, C.-Q.; Lin, A.-H.; Gu, W.; Chen, Z.-P.; Li, W.; Cai, B.-C. Thermosensitive liposomes with higher phase transition temperature for targeted drug delivery to tumor. Int. J. Pharm. 2014, 475, 408–415.
    • (2014) Int. J. Pharm , vol.475 , pp. 408-415
    • Chen, J.1    He, C.-Q.2    Lin, A.-H.3    Gu, W.4    Chen, Z.-P.5    Li, W.6    Cai, B.-C.7
  • 101
    • 84890953343 scopus 로고    scopus 로고
    • Phototriggerable liposomes: Current research and future perspectives
    • Puri, A. Phototriggerable liposomes: Current research and future perspectives. Pharmaceutics 2013, 6, 1–25.
    • (2013) Pharmaceutics , vol.6 , pp. 1-25
    • Puri, A.1
  • 102
    • 85017575689 scopus 로고    scopus 로고
    • Phase I study of thermally sensitive liposomes containing doxorubicin (ThermoDox) given during radiofrequency ablation (RFA) in patients with unresectable hepatic malignancies
    • Orlando, FL, USA, 19–21 January 2007; The American Society of Clinical Oncology: Alexandria, VA, USA
    • Wood, B.; Poon, R.; Neeman, Z.; Eugeni, M.; Locklin, J.; Dromi, S.; Kachala, S.; Probhakar, R.; Hahne, W.; Libutti, S. Phase I study of thermally sensitive liposomes containing doxorubicin (ThermoDox) given during radiofrequency ablation (RFA) in patients with unresectable hepatic malignancies. In Proceedings of the Gastrointestinal Cancers Symposium, Orlando, FL, USA, 19–21 January 2007; The American Society of Clinical Oncology: Alexandria, VA, USA, 2007.
    • (2007) Proceedings of the Gastrointestinal Cancers Symposium
    • Wood, B.1    Poon, R.2    Neeman, Z.3    Eugeni, M.4    Locklin, J.5    Dromi, S.6    Kachala, S.7    Probhakar, R.8    Hahne, W.9    Libutti, S.10
  • 104
    • 79551497883 scopus 로고    scopus 로고
    • The role of hyperthermia in the battle against cancer
    • Palazzi, M.; Maluta, S.; Dall’Oglio, S.; Romano, M. The role of hyperthermia in the battle against cancer. Tumori 2010, 96, 902.
    • (2010) Tumori , vol.96 , pp. 902
    • Palazzi, M.1    Maluta, S.2    Dall’Oglio, S.3    Romano, M.4
  • 105
    • 84886292840 scopus 로고    scopus 로고
    • Stimuli-responsive nanocarriers for drug delivery
    • Mura, S.; Nicolas, J.; Couvreur, P. Stimuli-responsive nanocarriers for drug delivery. Nat. Mater. 2013, 12, 991–1003.
    • (2013) Nat. Mater. , vol.12 , pp. 991-1003
    • Mura, S.1    Nicolas, J.2    Couvreur, P.3
  • 106
    • 84860471928 scopus 로고    scopus 로고
    • Nanoparticle delivery systems for cancer therapy: Advances in clinical and preclinical research
    • Egusquiaguirre, S.P.; Igartua, M.; Hernández, R.M.; Pedraz, J.L. Nanoparticle delivery systems for cancer therapy: Advances in clinical and preclinical research. Clin. Transl. Onco. 2012, 14, 83–93.
    • (2012) Clin. Transl. Onco. , vol.14 , pp. 83-93
    • Egusquiaguirre, S.P.1    Igartua, M.2    Hernández, R.M.3    Pedraz, J.L.4
  • 107
    • 68049142557 scopus 로고    scopus 로고
    • Clinical overview on Lipoplatin™: A successful liposomal formulation of cisplatin
    • Boulikas, T. Clinical overview on Lipoplatin™: A successful liposomal formulation of cisplatin. Expert Opin. Investig. Drugs 2009, 18, 1197–1218.
    • (2009) Expert Opin. Investig. Drugs , vol.18 , pp. 1197-1218
    • Boulikas, T.1
  • 108
    • 22944431611 scopus 로고    scopus 로고
    • Pharmacokinetics and adverse reactions of a new liposomal cisplatin (Lipoplatin): Phase I study
    • Sotiriosrigatos, E.D.; Viliotou, V.; Stathopoulos, J.G. Pharmacokinetics and adverse reactions of a new liposomal cisplatin (Lipoplatin): Phase I study. Oncol. Rep. 2005, 13, 589–595.
    • (2005) Oncol. Rep. , vol.13 , pp. 589-595
    • Sotiriosrigatos, E.D.1    Viliotou, V.2    Stathopoulos, J.G.3
  • 110
    • 77950461582 scopus 로고    scopus 로고
    • Study of liposomal cisplatin (Lipoplatin™) plus gemcitabine versus cisplatin plus gemcitabine as first line treatment in inoperable (stage IIIB/IV) non-small cell lung cancer
    • Mylonakis, N.; Athanasiou, A.; Ziras, N.; Angel, J.; Rapti, A.; Lampaki, S.; Politis, N.; Karanikas, C.; Kosmas, C. Phase II study of liposomal cisplatin (Lipoplatin™) plus gemcitabine versus cisplatin plus gemcitabine as first line treatment in inoperable (stage IIIB/IV) non-small cell lung cancer. Lung Cancer 2010, 68, 240–247.
    • (2010) Lung Cancer , vol.68 , pp. 240-247
    • Mylonakis, N.1    Athanasiou, A.2    Ziras, N.3    Angel, J.4    Rapti, A.5    Lampaki, S.6    Politis, N.7    Karanikas, C.8    Kosmas, C.9    Phase, I.I.10
  • 111
    • 22944467507 scopus 로고    scopus 로고
    • Systemic Lipoplatin infusion results in preferential tumor uptake in human studies
    • Boulikas, T.; Stathopoulos, G.P.; Volakakis, N.; Vougiouka, M. Systemic Lipoplatin infusion results in preferential tumor uptake in human studies. Anticancer Res. 2005, 25, 3031–3039.
    • (2005) Anticancer Res , vol.25 , pp. 3031-3039
    • Boulikas, T.1    Stathopoulos, G.P.2    Volakakis, N.3    Vougiouka, M.4
  • 113
    • 34548482374 scopus 로고    scopus 로고
    • Stealth liposomes: Review of the basic science, rationale, and clinical applications, existing and potential
    • Immordino, M.L.; Dosio, F.; Cattel, L. Stealth liposomes: Review of the basic science, rationale, and clinical applications, existing and potential. Int. J. Nanomed. 2006, 1, 297.
    • (2006) Int. J. Nanomed , vol.1 , pp. 297
    • Immordino, M.L.1    Dosio, F.2    Cattel, L.3
  • 114
    • 80055068792 scopus 로고    scopus 로고
    • Platinum formulations as anticancer drugs clinical and pre-clinical studies
    • Farrell, N.P. Platinum formulations as anticancer drugs clinical and pre-clinical studies. Curr. Top. Med. Chem. 2011, 11, 2623–2631.
    • (2011) Curr. Top. Med. Chem. , vol.11 , pp. 2623-2631
    • Farrell, N.P.1
  • 115
    • 1542382056 scopus 로고    scopus 로고
    • 268 A phase II trial of aroplatin (L-NDDP), a liposomal DACH platinum, in patients with metastatic colorectal cancer (CRC)-a preliminary report
    • Dragovich, T.; Mendelson, D.; Hoos, A.; Lewis, J.; Kurtin, S.; Richardson, K.; von Hoff, D. 268 A phase II trial of aroplatin (L-NDDP), a liposomal DACH platinum, in patients with metastatic colorectal cancer (CRC)-a preliminary report. Eur. J. Cancer Suppl. 2003, 1, S82–S83.
    • (2003) Eur. J. Cancer Suppl. , vol.1 , pp. S82-S83
    • Dragovich, T.1    Mendelson, D.2    Hoos, A.3    Lewis, J.4    Kurtin, S.5    Richardson, K.6    Von Hoff, D.7
  • 116
    • 0037714214 scopus 로고    scopus 로고
    • Tumour-inhibiting platinum complexes—State of the art and future perspectives
    • Springer: New York, NY, USA
    • Jakupec, M.; Galanski, M.; Keppler, B. Tumour-inhibiting platinum complexes—State of the art and future perspectives. In Reviews of physiology, Biochemistry and Pharmacology; Springer: New York, NY, USA, 2003; pp. 1–53.
    • (2003) In Reviews of Physiology, Biochemistry and Pharmacology , pp. 1-53
    • Jakupec, M.1    Galanski, M.2    Keppler, B.3
  • 117
    • 0029820711 scopus 로고    scopus 로고
    • Lyophilized preliposomal formulation of the non-cross-resistant anthracycline annamycin: Effect of surfactant on liposome formation, stability and size
    • Zou, Y.; Priebe, W.; Perez-Soler, R. Lyophilized preliposomal formulation of the non-cross-resistant anthracycline annamycin: Effect of surfactant on liposome formation, stability and size. Cancer Chemother. Pharmacol. 1996, 39, 103–108.
    • (1996) Cancer Chemother. Pharmacol. , vol.39 , pp. 103-108
    • Zou, Y.1    Priebe, W.2    Perez-Soler, R.3
  • 118
    • 0029122889 scopus 로고
    • Distribution of free and liposomal annamycin within human plasma is regulated by plasma triglyceride concentrations but not by lipid transfer protein
    • Wasan, K.M.; Perez-Soler, R. Distribution of free and liposomal annamycin within human plasma is regulated by plasma triglyceride concentrations but not by lipid transfer protein. J. Pharm. Sci. 1995, 84, 1094–1100.
    • (1995) J. Pharm. Sci. , vol.84 , pp. 1094-1100
    • Wasan, K.M.1    Perez-Soler, R.2
  • 119
    • 23444443192 scopus 로고
    • Antitumor activity of free and liposome-entrapped annamycin, a lipophilic anthracycline antibiotic with non-cross-resistance properties
    • Zou, Y.; Ling, Y.H.; Van, N.T.; Priebe, W.; Perez-Soler, R. Antitumor activity of free and liposome-entrapped annamycin, a lipophilic anthracycline antibiotic with non-cross-resistance properties. Cancer Res. 1994, 54, 1479–1484.
    • (1994) Cancer Res , vol.54 , pp. 1479-1484
    • Zou, Y.1    Ling, Y.H.2    Van, N.T.3    Priebe, W.4    Perez-Soler, R.5
  • 120
    • 33947588149 scopus 로고    scopus 로고
    • New therapeutic strategies for the treatment of acute lymphoblastic leukaemia
    • Pui, C.-H.; Jeha, S. New therapeutic strategies for the treatment of acute lymphoblastic leukaemia. Nat. Rev. Drug Discov. 2007, 6, 149–165.
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 149-165
    • Pui, C.-H.1    Jeha, S.2
  • 123
    • 12144290727 scopus 로고    scopus 로고
    • Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma
    • Zamboni, W.C.; Gervais, A.C.; Egorin, M.J.; Schellens, J.H.; Zuhowski, E.G.; Pluim, D.; Joseph, E.; Hamburger, D.R.; Working, P.K.; Colbern, G. Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma. Cancer Chemother. Pharmacol. 2004, 53, 329–336.
    • (2004) Cancer Chemother. Pharmacol. , vol.53 , pp. 329-336
    • Zamboni, W.C.1    Gervais, A.C.2    Egorin, M.J.3    Schellens, J.H.4    Zuhowski, E.G.5    Pluim, D.6    Joseph, E.7    Hamburger, D.R.8    Working, P.K.9    Colbern, G.10
  • 125
    • 34547741657 scopus 로고    scopus 로고
    • STEALTH® liposomal CKD-602, a topoisomerase I inhibitor, improves the therapeutic index in human tumor xenograft models
    • Yu, N.Y.; Conway, C.; Pena, R.L.; Chen, J.Y. STEALTH® liposomal CKD-602, a topoisomerase I inhibitor, improves the therapeutic index in human tumor xenograft models. Anticancer Res. 2007, 27, 2541–2545.
    • (2007) Anticancer Res , vol.27 , pp. 2541-2545
    • Yu, N.Y.1    Conway, C.2    Pena, R.L.3    Chen, J.Y.4
  • 126
  • 127
    • 0346392116 scopus 로고    scopus 로고
    • Development and characterization of a novel liposome-based formulation of SN-38
    • Zhang, J.A.; Xuan, T.; Parmar, M.; Ma, L.; Ugwu, S.; Ali, S.; Ahmad, I. Development and characterization of a novel liposome-based formulation of SN-38. Int. J. Pharm. 2004, 270, 93–107.
    • (2004) Int. J. Pharm. , vol.270 , pp. 93-107
    • Zhang, J.A.1    Xuan, T.2    Parmar, M.3    Ma, L.4    Ugwu, S.5    Ali, S.6    Ahmad, I.7
  • 129
    • 30544445340 scopus 로고    scopus 로고
    • A National Cancer Institute of Canada Clinical Trials Group Study–IND. 135: Phase I/II study of irinotecan (camptosar), oxaliplatin and raltitrexed (tomudex) (COT) in patients with advanced colorectal cancer
    • Maroun, J.; Jonker, D.; Seymour, L.; Goel, R.; Vincent, M.; Kocha, W.; Cripps, C.; Fisher, B.; Lister, D.; Malpage, A. A National Cancer Institute of Canada Clinical Trials Group Study–IND. 135: Phase I/II study of irinotecan (camptosar), oxaliplatin and raltitrexed (tomudex) (COT) in patients with advanced colorectal cancer. Eur. J. Cancer 2006, 42, 193–199.
    • (2006) Eur. J. Cancer , vol.42 , pp. 193-199
    • Maroun, J.1    Jonker, D.2    Seymour, L.3    Goel, R.4    Vincent, M.5    Kocha, W.6    Cripps, C.7    Fisher, B.8    Lister, D.9    Malpage, A.10
  • 130
    • 9644268054 scopus 로고    scopus 로고
    • Development and characterization of a novel Cremophor® EL free liposome-based paclitaxel (LEP-ETU) formulation
    • Zhang, J.A.; Anyarambhatla, G.; Ma, L.; Ugwu, S.; Xuan, T.; Sardone, T.; Ahmad, I. Development and characterization of a novel Cremophor® EL free liposome-based paclitaxel (LEP-ETU) formulation. Eur. J. Pharm. Biopharm. 2005, 59, 177–187.
    • (2005) Eur. J. Pharm. Biopharm. , vol.59 , pp. 177-187
    • Zhang, J.A.1    Anyarambhatla, G.2    Ma, L.3    Ugwu, S.4    Xuan, T.5    Sardone, T.6    Ahmad, I.7
  • 132
    • 84890315773 scopus 로고    scopus 로고
    • Bioequivalence of Liposome-Entrapped Paclitaxel Easy-To-Use (LEP-ETU) formulation and paclitaxel in polyethoxylated castor oil: A randomized, two-period crossover study in patients with advanced cancer
    • Slingerland, M.; Guchelaar, H.-J.; Rosing, H.; Scheulen, M.E.; van Warmerdam, L.J.; Beijnen, J.H.; Gelderblom, H. Bioequivalence of Liposome-Entrapped Paclitaxel Easy-To-Use (LEP-ETU) formulation and paclitaxel in polyethoxylated castor oil: A randomized, two-period crossover study in patients with advanced cancer. Clin. Ther. 2013, 35, 1946–1954.
    • (2013) Clin. Ther. , vol.35 , pp. 1946-1954
    • Slingerland, M.1    Guchelaar, H.-J.2    Rosing, H.3    Scheulen, M.E.4    Van Warmerdam, L.J.5    Beijnen, J.H.6
  • 136
    • 0034067560 scopus 로고    scopus 로고
    • The nonclinical safety evaluation of the anticancer drug ATRAGEN® (Liposomal all-trans-retinoic acid)
    • Wallace, T.L.; Larson, J.L.; Bazemore, S.A.; Wilson, C.W.; Cossum, P.A. The nonclinical safety evaluation of the anticancer drug ATRAGEN® (Liposomal all-trans-retinoic acid). Int. J. Toxicol. 2000, 19, 33–42.
    • (2000) Int. J. Toxicol , vol.19 , pp. 33-42
    • Wallace, T.L.1    Larson, J.L.2    Bazemore, S.A.3    Wilson, C.W.4    Cossum, P.A.5
  • 137
    • 0035169587 scopus 로고    scopus 로고
    • Treatment of newly diagnosed and relapsed acute promyelocytic leukemia with intravenous liposomal all-transretinoic acid
    • Douer, D.; Estey, E.; Santillana, S.; Bennett, J.M.; Lopez-Bernstein, G.; Boehm, K.; Williams, T. Treatment of newly diagnosed and relapsed acute promyelocytic leukemia with intravenous liposomal all-transretinoic acid. Blood 2001, 97, 73–80.
    • (2001) Blood , vol.97 , pp. 73-80
    • Douer, D.1    Estey, E.2    Santillana, S.3    Bennett, J.M.4    Lopez-Bernstein, G.5    Boehm, K.6    Williams, T.7
  • 138
    • 34047185817 scopus 로고    scopus 로고
    • Drug carriers in pharmaceutical design: Promises and progress
    • Dutta, R.C. Drug carriers in pharmaceutical design: Promises and progress. Curr. Pharm. Des. 2007, 13, 761–769.
    • (2007) Curr. Pharm. Des. , vol.13 , pp. 761-769
    • Dutta, R.C.1
  • 139
    • 84921038571 scopus 로고    scopus 로고
    • Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications
    • Wicki, A.; Witzigmann, D.; Balasubramanian, V.; Huwyler, J. Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications. J. Control. Release 2015, 200, 138–157.
    • (2015) J. Control. Release , vol.200 , pp. 138-157
    • Wicki, A.1    Witzigmann, D.2    Balasubramanian, V.3    Huwyler, J.4
  • 140
    • 13844266185 scopus 로고    scopus 로고
    • Separation of liposome-entrapped mitoxantrone from nonliposomal mitoxantrone in plasma
    • Ahmad, A.; Wang, Y.-F.; Ahmad, I. Separation of liposome-entrapped mitoxantrone from nonliposomal mitoxantrone in plasma: Pharmacokinetics in mice. Methods Enzymol. 2005, 391, 176–185.
    • (2005) Pharmacokinetics in Mice. Methods Enzymol. , vol.391 , pp. 176-185
    • Ahmad, A.1    Wang, Y.-F.2    Ahmad, I.3
  • 141
    • 85018501567 scopus 로고    scopus 로고
    • Advanced drug delivery in cancer therapy
    • Mitra, C.H.L.A., Cheng, K., Eds.; JohnWiley & Sons: Hoboken, NJ, USA
    • Tayi, W.; Cheng, K. Advanced drug delivery in cancer therapy. In Advanced Drug Delivery; Mitra, C.H.L.A., Cheng, K., Eds.; JohnWiley & Sons: Hoboken, NJ, USA, 2013.
    • (2013) Advanced Drug Delivery
    • Tayi, W.1    Cheng, K.2
  • 143
    • 84931825879 scopus 로고    scopus 로고
    • Liposomal delivery of nucleic acid-based anticancer therapeutics: BP-100–1.01. Expert Opin
    • Ashizawa, A.T.; Cortes, J. Liposomal delivery of nucleic acid-based anticancer therapeutics: BP-100–1.01. Expert Opin. Drug deliv. 2015, 12, 1107–1120.
    • (2015) Drug Deliv , vol.12 , pp. 1107-1120
    • Ashizawa, A.T.1    Cortes, J.2
  • 144
    • 85018515576 scopus 로고    scopus 로고
    • Safety, Pharmacokinetics, and Efficacy of BP-100–1.01 (Liposomal Grb-2 Antisense Oligonucleotide) in Patients with Refractory or Relapsed Acute Myeloid Leukemia (AML), Philadelphia Chromosome Positive Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL), and Myelodysplastic Syndrome (MDS)
    • Ohanian, M.; Kantarjian, H.M.; Ravandi, F.; Borthakur, G.; Garcia-Manero, G.; Andreeff, M.; Jabbour, E.; Konopleva, M.; Lim, M.; Pierce, S. Safety, Pharmacokinetics, and Efficacy of BP-100–1.01 (Liposomal Grb-2 Antisense Oligonucleotide) in Patients with Refractory or Relapsed Acute Myeloid Leukemia (AML), Philadelphia Chromosome Positive Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL), and Myelodysplastic Syndrome (MDS). Blood 2015, 126, 3801–3801.
    • (2015) Blood , vol.126 , pp. 3801
    • Ohanian, M.1    Kantarjian, H.M.2    Ravandi, F.3    Borthakur, G.4    Garcia-Manero, G.5    Andreeff, M.6    Jabbour, E.7    Konopleva, M.8    Lim, M.9    Pierce, S.10
  • 145
    • 85062147168 scopus 로고    scopus 로고
    • Nanotechnology for enhanced bioactivity of bioactive phytomolecules
    • Grumezescu, A.M., Ed.; Elsevier: Amsterdam, The Netherlands
    • Singh, R.; Kumari, P.; Kumar, S. Nanotechnology for enhanced bioactivity of bioactive phytomolecules. In Nutrient Delivery; Grumezescu, A.M., Ed.; Elsevier: Amsterdam, The Netherlands, 2016.
    • (2016) Nutrient Delivery
    • Singh, R.1    Kumari, P.2    Kumar, S.3
  • 146
    • 84908501841 scopus 로고    scopus 로고
    • Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery. Nat
    • Torchilin, V.P. Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery. Nat. Rev. Drug Discov. 2014, 13, 813–827.
    • (2014) Rev. Drug Discov , vol.13 , pp. 813-827
    • Torchilin, V.P.1
  • 147
    • 85018467000 scopus 로고    scopus 로고
    • Nanotherapeutic platforms for cancer treatment: From preclinical development to clinical application
    • Grumezescu, A., Holban, A.M., Eds.; Elsevier: Amsterdam, The Netherlands
    • Egusquiaguirre, S.P.; Pedraz, J.L.; Hernandez, R.M.; Igartua, M. Nanotherapeutic platforms for cancer treatment: From preclinical development to clinical application. In Nanoarchitectonics for Smart Delivery and Drug Targeting; Grumezescu, A., Holban, A.M., Eds.; Elsevier: Amsterdam, The Netherlands, 2016; pp. 813–869.
    • (2016) Nanoarchitectonics for Smart Delivery and Drug Targeting , pp. 813-869
    • Egusquiaguirre, S.P.1    Pedraz, J.L.2    Hernandez, R.M.3    Igartua, M.4
  • 148
    • 84880144292 scopus 로고    scopus 로고
    • Recent developments in nanoparticle-based siRNA delivery for cancer therapy
    • Lee, J.-M.; Yoon, T.-J.; Cho, Y.-S. Recent developments in nanoparticle-based siRNA delivery for cancer therapy. BioMed Res. Int. 2013.
    • (2013) Biomed Res. Int.
    • Lee, J.-M.1    Yoon, T.-J.2    Cho, Y.-S.3
  • 149
    • 84948717926 scopus 로고    scopus 로고
    • Clinical experiences with systemically administered siRNA-based therapeutics in cancer
    • Zuckerman, J.E.; Davis, M.E. Clinical experiences with systemically administered siRNA-based therapeutics in cancer. Nat. Rev. Drug Discov. 2015, 14, 843–856.
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 843-856
    • Zuckerman, J.E.1    Davis, M.E.2
  • 150
    • 84879074792 scopus 로고    scopus 로고
    • A review of the current status of siRNA nanomedicines in the treatment of cancer
    • Resnier, P.; Montier, T.; Mathieu, V.; Benoit, J.-P.; Passirani, C. A review of the current status of siRNA nanomedicines in the treatment of cancer. Biomaterials 2013, 34, 6429–6443.
    • (2013) Biomaterials , vol.34 , pp. 6429-6443
    • Resnier, P.1    Montier, T.2    Mathieu, V.3    Benoit, J.-P.4    Passirani, C.5
  • 152
    • 84870245984 scopus 로고    scopus 로고
    • Enhanced brain drug delivery: Safely crossing the blood–brain barrier. Drug Discov
    • Gaillard, P.J.; Visser, C.C.; Appeldoorn, C.C.; Rip, J. Enhanced brain drug delivery: Safely crossing the blood–brain barrier. Drug Discov. Today Technol. 2012, 9, e155–e160.
    • (2012) Today Technol , vol.9 , pp. e155-e160
    • Gaillard, P.J.1    Visser, C.C.2    Appeldoorn, C.C.3    Rip, J.4
  • 153
    • 84902962391 scopus 로고    scopus 로고
    • Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx, ®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study
    • Birngruber, T.; Raml, R.; Gladdines, W.; Gatschelhofer, C.; Gander, E.; Ghosh, A.; Kroath, T.; Gaillard, P.J.; Pieber, T.R.; Sinner, F. Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx, ®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study. J. Pharm. Sci. 2014, 103, 1945–1948.
    • (2014) J. Pharm. Sci , vol.103 , pp. 1945-1948
    • Birngruber, T.1    Raml, R.2    Gladdines, W.3    Gatschelhofer, C.4    Gander, E.5    Ghosh, A.6    Kroath, T.7    Gaillard, P.J.8    Pieber, T.R.9    Sinner, F.10
  • 154
    • 84997047916 scopus 로고    scopus 로고
    • To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine? J
    • Danhier, F. To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine? J. Control. Release 2016, 244, 108–121.
    • (2016) Control. Release , vol.244 , pp. 108-121
    • Danhier, F.1


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