Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy

Stem Cell Research and Therapy

Volumn 8, Issue 1, 2017, Pages

  Wang, Bingying ^a,b   Jia, Haoyuan ^a   Zhang, Bin ^a   Wang, Juanjuan ^a   Ji, Cheng ^a   Zhu, Xueming ^b   Yan, Yongmin ^a   Yin, Lei ^a   Yu, Jing ^a   Qian, Hui ^a   Xu, Wenrong ^a  

^a JIANGSU UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Autophagy; Cisplatin; Exosome; Human umbilical cord mesenchymal stem cell; Nephrotoxicity

Indexed keywords

3 METHYLADENINE; AUTOPHAGY RELATED PROTEIN 5; AUTOPHAGY RELATED PROTEIN 7; CD63 ANTIGEN; CD81 ANTIGEN; CD9 ANTIGEN; CISPLATIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 1BETA; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P70; RAPAMYCIN; 3-METHYLADENINE; ADENINE; ATG5 PROTEIN, RAT; ATG7 PROTEIN, RAT; BIOLOGICAL MARKER; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOSOME; FEMALE; FETUS; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; KIDNEY CAPSULE; KIDNEY FUNCTION; KIDNEY TUBULE CELL; LUNG FIBROBLAST; MESENCHYMAL STEM CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NEPHROTOXICITY; NONHUMAN; PARTICLE SIZE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; TRANSMISSION ELECTRON MICROSCOPY; TUNEL ASSAY; UMBILICAL CORD BLOOD CELL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; FIBROBLAST; GENE EXPRESSION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; NEPHRITIS; PATHOLOGY; PRIMARY CELL CULTURE; SPRAGUE DAWLEY RAT; TRANSPLANTATION; UMBILICAL CORD;

ADENINE; ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; AUTOPHAGY-RELATED PROTEIN 7; BIOMARKERS; CELL DIFFERENTIATION; CELL LINE; CISPLATIN; EPITHELIAL CELLS; EXOSOMES; FEMALE; FETUS; FIBROBLASTS; GENE EXPRESSION; HUMANS; MESENCHYMAL STROMAL CELLS; MICROTUBULE-ASSOCIATED PROTEINS; NEPHRITIS; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; SIROLIMUS; UMBILICAL CORD;

EID: 85018466363     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/s13287-016-0463-4     Document Type: Article

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