In vitro and in vivo antivirus activity of an antiprogrammed death-ligand 1 (PD-L1) ratbovine chimeric antibody against bovine leukemia virus infection

PLoS ONE

Volumn 12, Issue 4, 2017, Pages

  Nishimori, Asami ^a   Konnai, Satoru ^a   Okagawa, Tomohiro ^a   Maekawa, Naoya ^a   Ikebuchi, Ryoyo ^a   Goto, Shinya ^a   Sajiki, Yamato ^a   Suzuki, Yasuhiko ^b   Kohara, Junko ^c   Ogasawara, Satoshi ^d   Kato, Yukinari ^d   Murata, Shiro ^a   Ohashi, Kazuhiko ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c HOKKAIDO RESEARCH ORGANIZATION   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC ANTIBODY; MONOCLONAL ANTIBODY; PLASMID VECTOR; PROGRAMMED DEATH 1 LIGAND 1; ANTIVIRUS AGENT; GAMMA INTERFERON; HYBRID PROTEIN; VIRAL PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; BINDING ASSAY; BOVINE LEUKEMIA VIRUS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNE CELL FUNCTION ASSAY; IMMUNE RESPONSE; IMMUNIZATION; MALE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROVIRUS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR OCCUPANCY; UPREGULATION; ANIMAL; ANTIGEN ANTIBODY REACTION; B LYMPHOCYTE; BIOSYNTHESIS; BOVINE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENZOOTIC BOVINE LEUKOSIS; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; LYMPHOCYTE ACTIVATION; METABOLISM; MONONUCLEAR CELL; PHYSIOLOGY; RAT; VIROLOGY; VIRUS LOAD;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; ANTIVIRAL AGENTS; B-LYMPHOCYTES; B7-H1 ANTIGEN; CATTLE; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; ENZOOTIC BOVINE LEUKOSIS; INTERFERON-GAMMA; LEUKEMIA VIRUS, BOVINE; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; RATS; RECOMBINANT FUSION PROTEINS; VIRAL LOAD; VIRAL PROTEINS;

EID: 85018351182     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0174916     Document Type: Article

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