Selective loss of early differentiated, highly functional pd1high CD4 T cells with HIV progression

PLoS ONE

Volumn 10, Issue 12, 2015, Pages

  Paris, Robert M ^a,c   Petrovas, Constantinos ^a   Ferrando Martinez, Sara ^a   Moysi, Eirini ^a,b   Boswell, Kristin L ^a   Archer, Eva ^a   Yamamoto, Takuya ^a   Ambrozak, David ^a   Casazza, Joseph P ^a   Haubrich, Richard ^d   Connors, Mark ^a   Ake, Julie ^c   Kim, Jerome H ^e   Koup, Richard A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Military HIV Research Program   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e International Vaccine Institute   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR5; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAG PROTEIN; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 7 RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROGRAMMED DEATH 1 RECEPTOR; VIRUS DNA; VIRUS RNA; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CCR5 PROTEIN, HUMAN; CYTOKINE; PDCD1 PROTEIN, HUMAN;

ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; INFECTION SENSITIVITY; LYMPHOCYTE PROLIFERATION; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; UPREGULATION; VIRUS LOAD; VIRUS REPLICATION; BIOSYNTHESIS; CD4 LYMPHOCYTE COUNT; DISEASE COURSE; DRUG EFFECTS; FLOW CYTOMETRY; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; DISEASE PROGRESSION; FLOW CYTOMETRY; HIV INFECTIONS; HIV-1; HUMANS; POLYMERASE CHAIN REACTION; PROGRAMMED CELL DEATH 1 RECEPTOR; RECEPTORS, CCR5; VIRAL LOAD;

EID: 84956703782     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0144767     Document Type: Article

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