메뉴 건너뛰기




Volumn 33, Issue 6, 2017, Pages 814-821

WeSME: Uncovering mutual exclusivity of cancer drivers and beyond

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; BREAST TUMOR; FEMALE; GENETICS; HUMAN; MUTATION; PROCEDURES; TUMOR GENE;

EID: 85018313480     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btw242     Document Type: Article
Times cited : (62)

References (34)
  • 1
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Alexandrov, L.B. et al. (2013) Signatures of mutational processes in human cancer. Nature, 500, 415-421.
    • (2013) Nature , vol.500 , pp. 415-421
    • Alexandrov, L.B.1
  • 2
    • 84938600057 scopus 로고    scopus 로고
    • Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations
    • Babur, O. et al. (2015) Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations. Genome Biol., 16, 45.
    • (2015) Genome Biol. , vol.16 , pp. 45
    • Babur, O.1
  • 3
    • 84862523863 scopus 로고    scopus 로고
    • Sequence analysis of mutations and translocations across Breast cancer subtypes
    • Banerji, S. et al. (2012) Sequence analysis of mutations and translocations across breast cancer subtypes. Nature, 486, 405-409.
    • (2012) Nature , vol.486 , pp. 405-409
    • Banerji, S.1
  • 4
    • 84874188583 scopus 로고    scopus 로고
    • APOBEC3B is an enzymatic source of mutation in Breast cancer
    • Burns, M.B. et al. (2013) APOBEC3B is an enzymatic source of mutation in breast cancer. Nature, 494, 366-370.
    • (2013) Nature , vol.494 , pp. 366-370
    • Burns, M.B.1
  • 5
    • 84877254190 scopus 로고    scopus 로고
    • Integrated genomic characterization of endometrial carcinoma
    • Cancer Genome Atlas Research, N. et al.
    • Cancer Genome Atlas Research, N. et al. (2013) Integrated genomic characterization of endometrial carcinoma. Nature, 497, 67-73.
    • (2013) Nature , vol.497 , pp. 67-73
  • 6
    • 84924184255 scopus 로고    scopus 로고
    • APOBEC3B expression in Breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation
    • Cescon, D.W. et al. (2015) APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation. Proc. Natl. Acad. Sci. USA, 112, 2841-2846.
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 2841-2846
    • Cescon, D.W.1
  • 7
    • 84856535081 scopus 로고    scopus 로고
    • Mutual exclusivity analysis identifies oncogenic network modules
    • Ciriello, G. et al. (2012) Mutual exclusivity analysis identifies oncogenic network modules. Genome Res., 22, 398-406.
    • (2012) Genome Res. , vol.22 , pp. 398-406
    • Ciriello, G.1
  • 8
    • 0031816005 scopus 로고    scopus 로고
    • P300/CREB binding protein-related protein p270 is a component of Mammalian SWI/SNF complexes
    • Dallas, P.B. et al. (1998) p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes. Mol. Cell. Biol., 18, 3596-3603.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3596-3603
    • Dallas, P.B.1
  • 9
    • 73449108812 scopus 로고    scopus 로고
    • Epistatic interactions govern chemically-induced lung tumor susceptibility and kras mutation site in murine C57BL/ 6J-chra/J chromosome substitution strains
    • Dwyer-Nield, L.D. et al. (2010) Epistatic interactions govern chemically-induced lung tumor susceptibility and Kras mutation site in murine C57BL/ 6J-ChrA/J chromosome substitution strains. Int. J. Cancer J. Int. Cancer, 126, 125-132.
    • (2010) Int. J. Cancer J. Int. Cancer , vol.126 , pp. 125-132
    • Dwyer-Nield, L.D.1
  • 10
    • 79953737587 scopus 로고    scopus 로고
    • Diverse roles and interactions of the SWI/SNF chromatin remodeling complex revealed using global approaches
    • Euskirchen, G.M. et al. (2011) Diverse roles and interactions of the SWI/SNF chromatin remodeling complex revealed using global approaches. PLoS Genet., 7, e1002008.
    • (2011) PLoS Genet. , vol.7 , pp. e1002008
    • Euskirchen, G.M.1
  • 11
    • 84924303574 scopus 로고    scopus 로고
    • Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer
    • Harris, R.S. (2015) Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer. Breast Cancer Res.: BCR, 17, 8.
    • (2015) Breast Cancer Res.: BCR , vol.17 , pp. 8
    • Harris, R.S.1
  • 12
    • 84903390239 scopus 로고    scopus 로고
    • APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development
    • Henderson, S. et al. (2014) APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development. Cell Rep., 7, 1833-1841.
    • (2014) Cell Rep. , vol.7 , pp. 1833-1841
    • Henderson, S.1
  • 13
    • 84887084951 scopus 로고    scopus 로고
    • Network-based stratification of tumor mutations
    • Hofree, M. et al. (2013) Network-based stratification of tumor mutations. Nat. Methods, 10, 1108-1115.
    • (2013) Nat. Methods , vol.10 , pp. 1108-1115
    • Hofree, M.1
  • 14
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth, C. et al. (2013) Mutational landscape and significance across 12 major cancer types. Nature, 502, 333-339.
    • (2013) Nature , vol.502 , pp. 333-339
    • Kandoth, C.1
  • 15
    • 84931042163 scopus 로고    scopus 로고
    • MEMCover: Integrated analysis of mutual exclusivity and functional network reveals dysregulated pathways across multiple cancer types
    • Kim, Y.A. et al. (2015) MEMCover: integrated analysis of mutual exclusivity and functional network reveals dysregulated pathways across multiple cancer types. Bioinformatics, 31, i284-i292.
    • (2015) Bioinformatics , vol.31 , pp. i284-i292
    • Kim, Y.A.1
  • 16
    • 84962106951 scopus 로고    scopus 로고
    • Understanding genotype-phenotype effects in cancer via network approaches
    • Kim, Y.A., Cho, D-Y and Przytycka, T.M. (2016) Understanding Genotype-Phenotype Effects in Cancer via Network Approaches. PLoS Comput Biol., 12, e1004747.
    • (2016) PLoS Comput Biol. , vol.12 , pp. e1004747
    • Kim, Y.A.1    Cho, D.-Y.2    Przytycka, T.M.3
  • 17
    • 84872037386 scopus 로고    scopus 로고
    • Bridging the gap between genotype and phenotype via network approaches
    • Kim, Y.A. and Przytycka, T.M. (2012) Bridging the gap between genotype and phenotype via network approaches. Front. Genet., 3, 227.
    • (2012) Front. Genet. , vol.3 , pp. 227
    • Kim, Y.A.1    Przytycka, T.M.2
  • 18
    • 84880507665 scopus 로고    scopus 로고
    • Mutational heterogeneity in cancer and the search for new cancer-associated genes
    • Lawrence, M.S. et al. (2013) Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature, 499, 214-218.
    • (2013) Nature , vol.499 , pp. 214-218
    • Lawrence, M.S.1
  • 19
    • 84892833777 scopus 로고    scopus 로고
    • Discovery and saturation analysis of cancer genes across 21 tumour types
    • Lawrence, M.S. et al. (2014) Discovery and saturation analysis of cancer genes across 21 tumour types. Nature, 505, 495-501.
    • (2014) Nature , vol.505 , pp. 495-501
    • Lawrence, M.S.1
  • 20
    • 84878498657 scopus 로고    scopus 로고
    • Simultaneous identification of multiple driver pathways in cancer
    • Leiserson, M.D. et al. (2013) Simultaneous identification of multiple driver pathways in cancer. PLoS Comput. Biol., 9, e1003054.
    • (2013) PLoS Comput. Biol. , vol.9 , pp. e1003054
    • Leiserson, M.D.1
  • 21
    • 84938567345 scopus 로고    scopus 로고
    • CoMEt: A statistical approach to identify combinations of mutually exclusive alterations in cancer
    • Leiserson, M.D. et al. (2015) CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer. Genome Biol., 16, 160.
    • (2015) Genome Biol. , vol.16 , pp. 160
    • Leiserson, M.D.1
  • 22
    • 79955613209 scopus 로고    scopus 로고
    • Histone acetylation by CBP and p300 at doublestrand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors
    • Ogiwara, H. et al. (2011) Histone acetylation by CBP and p300 at doublestrand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene, 30, 2135-2146.
    • (2011) Oncogene , vol.30 , pp. 2135-2146
    • Ogiwara, H.1
  • 23
    • 84943237337 scopus 로고    scopus 로고
    • APOBEC3B-mediated cytidine deamination is required for estrogen receptor action in Breast cancer
    • Periyasamy, M. et al. (2015) APOBEC3B-mediated cytidine deamination is required for estrogen receptor action in breast cancer. Cell Rep., 13, 108-121.
    • (2015) Cell Rep. , vol.13 , pp. 108-121
    • Periyasamy, M.1
  • 24
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: A software environment for integrated models of biomolecular interaction networks
    • Shannon, P. et al. (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res., 13, 2498-2504.
    • (2003) Genome Res. , vol.13 , pp. 2498-2504
    • Shannon, P.1
  • 25
    • 0033592891 scopus 로고    scopus 로고
    • PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis
    • Su, Z.Z. et al. (1999) PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis. Proc. Natl. Acad. Sci. USA, 96, 15115-15120.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 15115-15120
    • Su, Z.Z.1
  • 26
    • 84925424005 scopus 로고    scopus 로고
    • The nucleolar ubiquitin-specific protease USP36 deubi-quitinates and stabilizes c-myc
    • Sun, X.X. et al. (2015) The nucleolar ubiquitin-specific protease USP36 deubi-quitinates and stabilizes c-Myc. Proc. Natl. Acad. Sci. USA, 112, 3734-3739.
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 3734-3739
    • Sun, X.X.1
  • 27
    • 84897386130 scopus 로고    scopus 로고
    • Modeling mutual exclusivity of cancer mutations
    • Szczurek, E. and Beerenwinkel, N. (2014) Modeling mutual exclusivity of cancer mutations. PLoS Comput. Biol., 10, e1003503.
    • (2014) PLoS Comput. Biol. , vol.10 , pp. e1003503
    • Szczurek, E.1    Beerenwinkel, N.2
  • 28
    • 84885129618 scopus 로고    scopus 로고
    • Comprehensive identification of mutational cancer driver genes across 12 tumor types
    • Tamborero, D. et al. (2013) Comprehensive identification of mutational cancer driver genes across 12 tumor types. Sci. Rep., 3, 2650.
    • (2013) Sci. Rep. , vol.3 , pp. 2650
    • Tamborero, D.1
  • 29
    • 84871995408 scopus 로고    scopus 로고
    • GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility
    • Theodorou, V. et al. (2013) GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility. Genome Res., 23, 12-22.
    • (2013) Genome Res. , vol.23 , pp. 12-22
    • Theodorou, V.1
  • 30
    • 33847293670 scopus 로고    scopus 로고
    • High-throughput oncogene mutation profiling in human cancer
    • Thomas, R.K. et al. (2007) High-throughput oncogene mutation profiling in human cancer. Nat. Genet., 39, 347-351.
    • (2007) Nat. Genet. , vol.39 , pp. 347-351
    • Thomas, R.K.1
  • 31
    • 84856532705 scopus 로고    scopus 로고
    • De novo discovery of mutated driver pathways in cancer
    • Vandin, F. et al. (2012) De novo discovery of mutated driver pathways in cancer. Genome Res., 22, 375-385.
    • (2012) Genome Res. , vol.22 , pp. 375-385
    • Vandin, F.1
  • 32
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein, B. and Kinzler, K.W. (2004) Cancer genes and the pathways they control. Nat. Med., 10, 789-799.
    • (2004) Nat. Med. , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 33
    • 84859727700 scopus 로고    scopus 로고
    • The role of innate APOBEC3G and adaptive AID immune responses in HLA-HIV/SIV immunized SHIV infected macaques
    • Wang, Y. et al. (2012) The role of innate APOBEC3G and adaptive AID immune responses in HLA-HIV/SIV immunized SHIV infected macaques. PLoS One, 7, e34433.
    • (2012) PLoS One , vol.7 , pp. e34433
    • Wang, Y.1
  • 34
    • 84923360343 scopus 로고    scopus 로고
    • Widespread genetic epistasis among cancer genes
    • Wang, X. et al. (2014) Widespread genetic epistasis among cancer genes. Nat. Commun., 5, 4828.
    • (2014) Nat. Commun. , vol.5 , pp. 4828
    • Wang, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.