-
1
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
TCGA
-
TCGA (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
2
-
-
84875758730
-
Lessons from the Cancer Genome
-
Garraway LA, Lander ES, (2013) Lessons from the Cancer Genome. Cell 153: 17-37.
-
(2013)
Cell
, vol.153
, pp. 17-37
-
-
Garraway, L.A.1
Lander, E.S.2
-
3
-
-
79953902594
-
Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors
-
Miller C, Settle S, Sulman E, Aldape K, Milosavljevic A, (2011) Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors. BMC Medical Genomics 4: 34+.
-
(2011)
BMC Medical Genomics
, vol.4
-
-
Miller, C.1
Settle, S.2
Sulman, E.3
Aldape, K.4
Milosavljevic, A.5
-
4
-
-
84856532705
-
De Novo discovery of mutated driver pathways in cancer
-
Vandin F, Upfal E, Raphael BJ, (2012) De Novo discovery of mutated driver pathways in cancer. Genome Res 22: 375-385.
-
(2012)
Genome Res
, vol.22
, pp. 375-385
-
-
Vandin, F.1
Upfal, E.2
Raphael, B.J.3
-
5
-
-
84869447682
-
Efficient methods for identifying mutated driver pathways in cancer
-
Zhao J, Zhang S, Wu LY, Zhang XS, (2012) Efficient methods for identifying mutated driver pathways in cancer. Bioinformatics 28: 2940-2947.
-
(2012)
Bioinformatics
, vol.28
, pp. 2940-2947
-
-
Zhao, J.1
Zhang, S.2
Wu, L.Y.3
Zhang, X.S.4
-
6
-
-
84856535081
-
Mutual exclusivity analysis identifies oncogenic network modules
-
Ciriello G, Cerami E, Sander C, Schultz N, (2012) Mutual exclusivity analysis identifies oncogenic network modules. Genome research 22: 398-406.
-
(2012)
Genome Research
, vol.22
, pp. 398-406
-
-
Ciriello, G.1
Cerami, E.2
Sander, C.3
Schultz, N.4
-
8
-
-
48749118242
-
Combinatorial patterns of somatic gene mutations in cancer
-
Yeang CH, Mccormick F, Levine A, (2008) Combinatorial patterns of somatic gene mutations in cancer. FASEB J 22: 2605-2622.
-
(2008)
FASEB J
, vol.22
, pp. 2605-2622
-
-
Yeang, C.H.1
Mccormick, F.2
Levine, A.3
-
9
-
-
0032521433
-
Mutational analysis of the APC/betacatenin/Tcf pathway in colorectal cancer
-
Sparks AB, Morin PJ, Vogelstein B, Kinzler KW, (1998) Mutational analysis of the APC/betacatenin/Tcf pathway in colorectal cancer. Cancer Res 58: 1130-1134.
-
(1998)
Cancer Res
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
10
-
-
0037194728
-
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status
-
Rajagopalan H, Bardelli A, Lengauer C, Kinzler KW, Vogelstein B, et al. (2002) Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature 418: 934.
-
(2002)
Nature
, vol.418
, pp. 934
-
-
Rajagopalan, H.1
Bardelli, A.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
11
-
-
79959873016
-
Correlation of somatic mutation and expression identifies genes important in human glioblastoma progression and survival
-
Masica DL, Karchin R, (2011) Correlation of somatic mutation and expression identifies genes important in human glioblastoma progression and survival. Cancer Research 71: 4550-4561.
-
(2011)
Cancer Research
, vol.71
, pp. 4550-4561
-
-
Masica, D.L.1
Karchin, R.2
-
12
-
-
84882652197
-
Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma
-
Szczurek E, Misra N, Vingron M, (2013) Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma. International Journal of Cancer 133: 2123-2132.
-
(2013)
International Journal of Cancer
, vol.133
, pp. 2123-2132
-
-
Szczurek, E.1
Misra, N.2
Vingron, M.3
-
13
-
-
84874025843
-
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
-
Cibulskis K, Lawrence MS, Carter SL, Sivachenko A, Jaffe D, et al. (2013) Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat Biotech 31: 213-219.
-
(2013)
Nat Biotech
, vol.31
, pp. 213-219
-
-
Cibulskis, K.1
Lawrence, M.S.2
Carter, S.L.3
Sivachenko, A.4
Jaffe, D.5
-
14
-
-
84885074034
-
The Somatic Genomic Landscape of Glioblastoma
-
Brennan CW, Verhaak RGW, McKenna A, Campos B, Noushmehr H, et al. (2013) The Somatic Genomic Landscape of Glioblastoma. Cell 155: 462-477.
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.W.2
McKenna, A.3
Campos, B.4
Noushmehr, H.5
-
15
-
-
84884997982
-
Emerging landscape of oncogenic signatures across human cancers
-
Ciriello G, Miller ML, Aksoy BA, Senbabaoglu Y, Schultz N, et al. (2013) Emerging landscape of oncogenic signatures across human cancers. Nat Genet 45: 1127-1133.
-
(2013)
Nat Genet
, vol.45
, pp. 1127-1133
-
-
Ciriello, G.1
Miller, M.L.2
Aksoy, B.A.3
Senbabaoglu, Y.4
Schultz, N.5
-
16
-
-
0000646447
-
Likelihood ratio tests for model selection and non-nested hypotheses
-
Vuong QH, (1989) Likelihood ratio tests for model selection and non-nested hypotheses. Econometrica 57: 307-33.
-
(1989)
Econometrica
, vol.57
, pp. 307-333
-
-
Vuong, Q.H.1
-
17
-
-
0033997322
-
The role of membrane-associated adaptors in T cell receptor signalling
-
Zhang W, Samelson LE, (2000) The role of membrane-associated adaptors in T cell receptor signalling. Semin Immunol 12: 35-41.
-
(2000)
Semin Immunol
, vol.12
, pp. 35-41
-
-
Zhang, W.1
Samelson, L.E.2
-
18
-
-
0032479864
-
T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane
-
Bruyns E, Marie-Cardine A, Kirchgessner H, Sagolla K, Shevchenko A, et al. (1998) T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane. J Exp Med 188: 561-575.
-
(1998)
J Exp Med
, vol.188
, pp. 561-575
-
-
Bruyns, E.1
Marie-Cardine, A.2
Kirchgessner, H.3
Sagolla, K.4
Shevchenko, A.5
-
19
-
-
68549115631
-
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma
-
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, et al. (2008) Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harb Symp Quant Biol 73: 427-437.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 427-437
-
-
Zheng, H.1
Ying, H.2
Yan, H.3
Kimmelman, A.C.4
Hiller, D.J.5
-
20
-
-
0038666344
-
The gene ratios c-MYC:cyclin-dependent kinase (CDK)N2A and CCND1:CDKN2A correlate with poor prognosis in squamous cell carcinoma of the head and neck
-
Akervall J, Bockmuhl U, Petersen I, Yang K, Carey TE, et al. (2003) The gene ratios c-MYC:cyclin-dependent kinase (CDK)N2A and CCND1:CDKN2A correlate with poor prognosis in squamous cell carcinoma of the head and neck. Clin Cancer Res 9: 1750-1755.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1750-1755
-
-
Akervall, J.1
Bockmuhl, U.2
Petersen, I.3
Yang, K.4
Carey, T.E.5
-
21
-
-
0034050050
-
Loss of PTEN facilitates HIF-1-mediated gene expression
-
Zundel W, Schindler C, Haas-Kogan D, Koong A, Kaper F, et al. (2000) Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev 14: 391-396.
-
(2000)
Genes Dev
, vol.14
, pp. 391-396
-
-
Zundel, W.1
Schindler, C.2
Haas-Kogan, D.3
Koong, A.4
Kaper, F.5
-
22
-
-
78651482046
-
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
-
Song MS, Carracedo A, Salmena L, Song SJ, Egia A, et al. (2011) Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner. Cell 144: 187-199.
-
(2011)
Cell
, vol.144
, pp. 187-199
-
-
Song, M.S.1
Carracedo, A.2
Salmena, L.3
Song, S.J.4
Egia, A.5
-
23
-
-
34548677928
-
Comment on "The consensus coding sequences of human breast and colorectal cancers"
-
Getz G, Hoing H, Mesirov JP, Golub TR, Meyerson M, et al. (2007) Comment on "The consensus coding sequences of human breast and colorectal cancers". Science 317: 1500.
-
(2007)
Science
, vol.317
, pp. 1500
-
-
Getz, G.1
Hoing, H.2
Mesirov, J.P.3
Golub, T.R.4
Meyerson, M.5
-
24
-
-
38049100456
-
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
-
Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, et al. (2007) Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci USA 104: 20007-20012.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20007-20012
-
-
Beroukhim, R.1
Getz, G.2
Nghiemphu, L.3
Barretina, J.4
Hsueh, T.5
-
25
-
-
84866002291
-
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
-
Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, et al. (2012) The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data. Cancer Discovery 2: 401-404.
-
(2012)
Cancer Discovery
, vol.2
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
Gross, B.E.4
Sumer, S.O.5
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