Sphingolipids

Biochemistry of Lipids, Lipoproteins and Membranes: Sixth Edition

Volumn , Issue , 2016, Pages 297-326

  Futerman, Anthony H ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Ceramide; Glycosphingolipids; Human disease; Lipid biosynthesis; Lipid degradation; Lipid signalling; Rafts; Sphingosine 1 phosphate

Indexed keywords

EID: 85018193899     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-444-63438-2.00010-9     Document Type: Chapter

References (45)

1. Beckmann N., et al. Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons. Front. Physiol. 2014, 5:331.
2. Bejaoui K., et al. SPTLC1 is mutated in hereditary sensory neuropathy, type 1. Nat. Genet. 2001, 27(3):261-262.
3. Bigaud M., et al. Second generation S1P pathway modulators: research strategies and clinical developments. Biochim. Biophys. Acta 2014, 1841(5):745-758.
4. Brinkmann V. FTY720 (fingolimod) in multiple sclerosis: therapeutic effects in the immune and the central nervous system. Br. J. Pharmacol. 2009, 158(5):1173-1182.
5. Brown D.A., Rose J.K. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell 1992, 68(3):533-544.
6. D'Angelo G., et al. Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. Nature 2013, 501(7465):116-120.
7. Donati C., Cencetti F., Bruni P. New insights into the role of sphingosine 1-phosphate and lysophosphatidic acid in the regulation of skeletal muscle cell biology. Biochim. Biophys. Acta 2013, 1831(1):176-184.
8. Futerman A.H., Riezman H. The ins and outs of sphingolipid synthesis. Trends Cell Biol 2005, 15(6):312-318.
9. Goñi F.M., Alonso A. Effects of ceramide and other simple sphingolipids on membrane lateral structure. Biochim. Biophys. Acta 2009, 1788(1):169-177.
10. Grassme H., et al. Acidic sphingomyelinase mediates entry of N-gonorrhoeae into nonphagocytic cells. Cell 1997, 91(5):605-615.
11. Gravel R.A., et al. The GM2 gangliosidosis. The Metabolic and Molecular Bases of Inherited Disease 2001, 3827-3876. McGraw-Hill Inc. C.R. Scriver (Ed.).
12. Hanada K., et al. CERT-mediated trafficking of ceramide. Biochim. Biophys. Acta 2009, 1791(7):684-691.
13. Hanada K., et al. Molecular machinery for non-vesicular trafficking of ceramide. Nature 2003, 426(6968):803-809.
14. Hannun Y.A., Obeid L.M. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 2008, 9(2):139-150.
15. Hannun Y.A., et al. Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding invitro and in human platelets. J. Biol. Chem. 1986, 261(27):12604-12609.
16. Hannun Y.A., Luberto C., Argraves K.M. Enzymes of sphingolipid metabolism: from modular to integrative signaling. Biochemistry 2001, 40(16):4893-4903.
17. Horinouchi K., et al. Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease. Nat. Genet. 1995, 10(3):288-293.
18. Ichikawa S., Hirabayashi Y. Glucosylceramide synthase and glycosphingolipid synthesis. Trends Cell. Biol. 1998, 8:198-202.
19. Ikushiro H., Hayashi H. Mechanistic enzymology of serine palmitoyltransferase. Biochim. Biophys. Acta 2011, 1814(11):1474-1480.
20. Kolesnick R.N., Paley A.E. 1,2-diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. J. Biol. Chem. 1987, 262(19):9204-9210.
21. Kolter T., Sandhoff K. Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids. Annu. Rev. Cell Dev. Biol. 2005, 21:81-103.
22. Kornhuber J., et al. The ceramide system as a novel antidepressant target. Trends Pharmacol. Sci. 2014, 1-12.
23. Levy M., Futerman A.H. Mammalian ceramide synthases. IUBMB Life 2010, 62(5):347-356.
24. Lipsky N.G., Pagano R.E. A vital stain for the Golgi. Science 1985, 228:745-747.
25. Lowther J., et al. Structural, mechanistic and regulatory studies of serine palmitoyltransferase. Biochem. Soc. Trans. 2012, 40(3):547-554.
26. Maceyka M., Spiegel S. Sphingolipid metabolites in inflammatory disease. Nature 2014, 510(7503):58-67.
27. Matloubian M., et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 2004, 427(6972):355-360.
28. Merrill A.H.J. Sphingolipids. Biochemistry of Lipids, Lipoproteins and Membranes 2008, 364-397. Elsevier, Amsterdam. D.E. Vance, J.E. Vance (Eds.).
29. Merrill A.H. Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. Chem. Rev. 2011, 111(10):6387-6422.
30. Paris F., et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001, 293(5528):293-297.
31. Park J.-W., Park W.-J., Futerman A.H. Ceramide synthases as potential targets for therapeutic intervention in human diseases. Biochim. Biophys. Acta 2014, 1841:671-681.
32. Platt F.M. Sphingolipid lysosomal storage disorders. Nature 2014, 510(7503):68-75.
33. Rosen H., et al. Sphingosine 1-phosphate receptor signaling. Annu. Rev. Biochem. 2009, 78:743-768.
34. Saddoughi S.A., Ogretmen B. Diverse functions of ceramide in cancer cell death and proliferation. Adv. Cancer Res. 2013, 117:37-58.
35. Sandhoff K., Harzer K. Gangliosides and gangliosidoses: principles of molecular and metabolic pathogenesis. J. Neurosci. 2013, 33(25):10195-10208.
36. Simons K., Gerl M.J. Revitalizing membrane rafts: new tools and insights. Nat. Rev. Mol. Cell Biol. 2010, 11(10):688-699.
37. Simons K., Ikonen E. Functional rafts in cell membranes. Nature 1997, 387(6633):569-572.
38. Spiegel S., Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat. Rev. Mol. Cell Biol. 2003, 4(5):397-407.
39. Thudicum J.L.W. A Treatise on the Chemical Composition of the Brain, Hamden 1874, Republished in 1962 by Archon Books.
40. Tidhar R., Futerman A.H. The complexity of sphingolipid biosynthesis in the endoplasmic reticulum. Biochim. Biophys. Acta 2013, 1833(11):2511-2518.
41. Tirodkar T.S., Voelkel-Johnson C. Sphingolipids in apoptosis. Exp. Oncol. 2012, 34(3):231-242.
42. Venkataraman K., Futerman A.H. Comparison of the metabolism of L-erythro- and L-threo-sphinganines and ceramides in cultured cells and in subcellular fractions. Biochim. Biophys. Acta 2001, 1530(2-3):219-226.
43. Zhang H., et al. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J. Cell Biol. 1991, 114:155-167.
44. Zhang Y., et al. Ceramide-enriched membrane domains-structure and function. Biochim. Biophys. Acta 2009, 1788(1):178-183.
45. Zigdon H., Meshcheriakova A., Futerman A.H. From sheep to mice to cells: tools for the study of the sphingolipidoses. Biochim. Biophys. Acta 2014, 1841(8):1189-1199.