Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells

Journal of Biological Chemistry

Volumn 292, Issue 14, 2017, Pages 5665-5675

  Lee, Hak Joo ^a,b   Lee, Doug Yoon ^a   Mariappan, Meenalakshmi M ^a,b   Feliers, Denis ^a,b   Ghosh Choudhury, Goutam ^a,b   Abboud, Hanna E ^a,b   Gorin, Yves ^a   Kasinath, Balakuntalam S ^a,b  

^a University of Texas Health Science Center   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CELLS; CYTOLOGY; ENZYME ACTIVITY; GLUCOSE; HYDROGEN SULFIDE; NITRIC OXIDE; PROTEINS; SULFUR DETERMINATION;

AMP-ACTIVATED PROTEIN KINASE; EPITHELIAL CELLS; INDUCIBLE NITRIC OXIDE SYNTHASE; MATRIX PROTEINS; REACTIVE OXYGEN SPECIES; RENAL EPITHELIAL CELLS; SODIUM HYDROSULFIDE; THERAPEUTIC TARGETS;

GLUCOSE OXIDASE;

ACETYL COENZYME A CARBOXYLASE; ADENYLATE KINASE; HYDROGEN SULFIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; LAMININ; LAMININ GAMMA1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; AMIDINE; BENZYLAMINE DERIVATIVE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE; NITRIC OXIDE; NOS2 PROTEIN, MOUSE; NOX4 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SCLEROPROTEIN;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETIC NEPHROPATHY; ENZYME INHIBITION; EPITHELIUM CELL; GLOMERULUS EPITHELIUM; KIDNEY TUBULE FUNCTION; MESANGIUM CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PODOCYTE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DIABETIC NEPHROPATHIES; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; KIDNEY PROXIMAL TUBULE; METABOLISM; PATHOLOGY;

AMIDINES; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BENZYLAMINES; DIABETIC NEPHROPATHIES; EPITHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; HYDROGEN SULFIDE; KIDNEY TUBULES, PROXIMAL; MICE; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS;

EID: 85017333461     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.766758     Document Type: Article

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