AMP-activated protein kinase inhibits TGF-β-, angiotensin II-, aldosterone-, high glucose-, and albumin-induced epithelial-mesenchymal transition

American Journal of Physiology - Renal Physiology

Volumn 304, Issue 6, 2013, Pages

  Lee, Jang Han ^a   Kim, Ji Hyun ^a   Kim, Ja Seon ^a   Chang, Jai Won ^a   Kim, Soon Bae ^a   Park, Jung Sik ^a   Lee, Sang Koo ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

AMPK; EMT; Heme oxygenase 1; Nox4; ROS; Thioredoxin

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE PHOSPHATE; ACETYLCYSTEINE; ALBUMIN; ALDOSTERONE; ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN II; GLUCOSE; HEME OXYGENASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; THIOREDOXIN; TIRON; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; (6-(4-(2-PIPERIDIN-1-YLETHOXY)PHENYL))-3-PYRIDIN-4-YLPYRAZOLO(1,5-A)PYRIMIDINE; (6 (4 (2 PIPERIDIN 1 YLETHOXY)PHENYL)) 3 PYRIDIN 4 YLPYRAZOLO(1,5 A)PYRIMIDINE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ALBUMINOID; DRUG DERIVATIVE; HMOX1 PROTEIN, HUMAN; NOX4 PROTEIN, HUMAN; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RIBONUCLEOSIDE;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; KIDNEY FIBROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; CELL LINE; ENZYMOLOGY; METABOLISM; NEPHROSCLEROSIS;

ALBUMINS; ALDOSTERONE; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANGIOTENSIN II; CELL LINE; EPITHELIAL-MESENCHYMAL TRANSITION; GLUCOSE; HEME OXYGENASE-1; HUMANS; METFORMIN; NADPH OXIDASE; NEPHROSCLEROSIS; PYRAZOLES; PYRIMIDINES; REACTIVE OXYGEN SPECIES; RIBONUCLEOSIDES; THIOREDOXINS; TRANSFORMING GROWTH FACTOR BETA;

MLCS; MLOWN;

EID: 84877928942     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00148.2012     Document Type: Article

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