A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

Nature Medicine

Volumn 23, Issue 6, 2017, Pages 763-767

  Shan, Chao ^a   Muruato, Antonio E ^b   Nunes, Bruno T D ^a,c   Luo, Huanle ^a   Xie, Xuping ^a   Medeiros, Daniele B A ^a,c   Wakamiya, Maki ^a   Tesh, Robert B ^a,b   Barrett, Alan D ^a,b   Wang, Tian ^a   Weaver, Scott C ^a,b   Vasconcelos, Pedro F C ^c,d   Rossi, Shannan L ^a,b   Shi, Pei Yong ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c INSTITUTO EVANDRO CHAGAS   (Brazil)

^d UNIVERSIDADE DO ESTADO DO PARÁ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

LIVE VACCINE; NEUTRALIZING ANTIBODY; NUCLEOTIDE; VIRUS RNA; ZIKA VIRUS VACCINE; 3' UNTRANSLATED REGION; INTERFERON; INTERFERON RECEPTOR;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL MODEL; GENOME; IMMUNITY; INOCULATION; MOSQUITO; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SYNTHESIS; T LYMPHOCYTE; VIREMIA; VIRULENCE; WILD TYPE; AEDES; ANIMAL; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MOSQUITO VECTOR; MUTATION; REAL TIME POLYMERASE CHAIN REACTION; VACCINE IMMUNOGENICITY; VERO CELL LINE; VIROLOGY; VIRUS REPLICATION; ZIKA VIRUS; ZIKA VIRUS INFECTION;

3' UNTRANSLATED REGIONS; AEDES; ANIMALS; ANTIBODIES, NEUTRALIZING; CERCOPITHECUS AETHIOPS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOGENICITY, VACCINE; INTERFERON TYPE I; MICE; MICE, KNOCKOUT; MOSQUITO VECTORS; MUTATION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, INTERFERON; RNA, VIRAL; VACCINES, ATTENUATED; VERO CELLS; VIRUS REPLICATION; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85017269111     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4322     Document Type: Article

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