Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease

Science

Volumn 354, Issue 6316, 2016, Pages 1148-1152

  Akiyama, Benjamin M ^a   Laurence, Hannah M ^a,b   Massey, Aaron R ^a   Costantino, David A ^a   Xie, Xuping ^c   Yang, Yujiao ^c   Shi, Pei Yong ^c   Nix, Jay C ^d   Beckham, J David ^a   Kieft, Jeffrey S ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXONUCLEASE; PROTEIN; TRANSFER RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA; VIRUS RNA; XRN1 PROTEIN; XRRNA; EXORIBONUCLEASE;

CELLS AND CELL COMPONENTS; ENZYME; ENZYME ACTIVITY; MOSQUITO; MUTATION; PATHOGENICITY; RNA; RODENT; VIRUS;

3' UNTRANSLATED REGION; AEDES ALBOPICTUS; ANIMAL CELL; ANTICODON; ARTICLE; BASE PAIRING; CONFORMATIONAL TRANSITION; DENGUE VIRUS; EPITHELIUM CELL; GENE MUTATION; HUMAN; HUMAN CELL; MOUSE; MULTI PSEUDOKNOT STRUCTURE; MURRAY VALLEY ENCEPHALITIS VIRUS; NERVE CELL; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RNA STRUCTURE; SEQUENCE ALIGNMENT; STATIC ELECTRICITY; VIRUS VIRULENCE; WILD TYPE; X RAY; ZIKA FEVER; ZIKA VIRUS; ANIMAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; CONFORMATION; GENETICS; METABOLISM; MOSQUITO; MUTATION; VERO CELL LINE; VIROLOGY;

MUS; ZIKA VIRUS;

ANIMALS; CERCOPITHECUS AETHIOPS; CULICIDAE; EPITHELIAL CELLS; EXORIBONUCLEASES; HUMANS; MICE; MUTATION; NEURONS; NUCLEIC ACID CONFORMATION; RNA, UNTRANSLATED; RNA, VIRAL; VERO CELLS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 84996940106     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aah3963     Document Type: Article

References (30)

1. J. S. Mackenzie, D. J. Gubler, L. R. Petersen, Nat. Med. 10 (suppl.), S98-S109 (2004).
2. L. R. Petersen, D. J. Jamieson, A. M. Powers, M. A. Honein, N. Engl. J. Med. 374, 1552-1563 (2016).
3. B. D. Lindenbach, H. J. Thiel, C. M. Rice, in Fields Virology, D. M. Knipe, P. M. Howley, Eds. (Lippincott Williams & Wilkins, ed. 5, 2007), chap. 33.
4. G. P. Pijlman et al., Cell Host Microbe 4, 579-591 (2008).
5. G. Manokaran et al., Science 350, 217-221 (2015).
6. A. Schuessler et al., J. Virol. 86, 5708-5718 (2012).
7. E. Schnettler et al., J. Virol. 86, 13486-13500 (2012).
8. J. A. Roby, G. P. Pijlman, J. Wilusz, A. A. Khromykh, Viruses 6, 404-427 (2014).
9. K. Bidet, D. Dadlani, M. A. Garcia-Blanco, PLOS Pathog. 10, e1004242 (2014).
10. S. L. Moon et al., Virology 485, 322-329 (2015).
11. S. L. Moon et al., RNA 18, 2029-2040 (2012).
12. A. M. Ward et al., RNA Biol. 8, 1173-1186 (2011).
13. M. M. Emara, H. Liu, W. G. Davis, M. A. Brinton, J. Virol. 82, 10657-10670 (2008).
14. G. P. Göertz et al., J. Virol. 90, 10145-10159 (2016).
15. A. P. Durbin et al., J. Infect. Dis. 191, 710-718 (2005).
16. S. M. Villordo, C. V. Filomatori, I. Sánchez-Vargas, C. D. Blair, A. V. Gamarnik, PLOS Pathog. 11, e1004604 (2015).
17. V. Proutski, E. A. Gould, E. C. Holmes, Nucleic Acids Res. 25, 1194-1202 (1997).
18. J. S. Kieft, J. L. Rabe, E. G. Chapman, RNA Biol. 12, 1169-1177 (2015).
19. E. G. Chapman, S. L. Moon, J. Wilusz, J. S. Kieft, eLife 3, e01892 (2014).
20. S. M. Villordo, J. M. Carballeda, C. V. Filomatori, A. V. Gamarnik, Trends Microbiol. 24, 270-283 (2016).
21. E. G. Chapman et al., Science 344, 307-310 (2014).
22. A. Funk et al., J. Virol. 84, 11407-11417 (2010).
23. P. A. Silva, C. F. Pereira, T. J. Dalebout, W. J. Spaan, P. J. Bredenbeek, J. Virol. 84, 11395-11406 (2010).
24. R. Y. Chang et al., Vet. Microbiol. 166, 11-21 (2013).
25. M. Levitt, Nature 224, 759-763 (1969).
26. L. D. Sherlin et al., J. Mol. Biol. 299, 431-446 (2000).
27. C. Shan et al., Cell Host Microbe 19, 891-900 (2016).
28. M. Jinek, S. M. Coyle, J. A. Doudna, Mol. Cell 41, 600-608 (2011).
29. J. H. Chang, S. Xiang, K. Xiang, J. L. Manley, L. Tong, Nat. Struct. Mol. Biol. 18, 270-276 (2011).
30. N. B. Leontis, E. Westhof, RNA 7, 499-512 (2001).