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Volumn 38, Issue , 2017, Pages 279-294

Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health

(13)  Manrai, Arjun K a   Cui, Yuxia b   Bushel, Pierre R b   Hall, Molly c   Karakitsios, Spyros d   Mattingly, Carolyn J e   Ritchie, Marylyn c,f   Schmitt, Charles g   Sarigiannis, Denis A d   Thomas, Duncan C h   Wishart, David i   Balshaw, David M b   Patel, Chirag J a,j  


Author keywords

Bioinformatics; Data standards; Environment wide association studies; Exposures; Genomics

Indexed keywords

BIOMEDICINE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; GENE INTERACTION; GENETIC ASSOCIATION; HUMAN; KNOWLEDGE; MEDICAL INFORMATICS; PRIORITY JOURNAL; PUBLIC HEALTH; REVIEW; BIOLOGY; ECOSYSTEM; MEDICAL RESEARCH; RISK FACTOR;

EID: 85017186712     PISSN: 01637525     EISSN: 15452093     Source Type: Book Series    
DOI: 10.1146/annurev-publhealth-082516-012737     Document Type: Review
Times cited : (88)

References (73)
  • 1
    • 85017149045 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. 1995. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. B 57(1):289-300
    • (1995) J. R. Stat. Soc. B , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 2
    • 84855452259 scopus 로고    scopus 로고
    • Estimating the health effects of exposure to multipollutant mixture
    • Billionnet C, Sherrill D, Annesi-Maesano I. 2012. Estimating the health effects of exposure to multipollutant mixture. Ann. Epidemiol. 22(2):126-41
    • (2012) Ann. Epidemiol , vol.22 , Issue.2 , pp. 126-141
    • Billionnet, C.1    Sherrill, D.2    Annesi-Maesano, I.3
  • 3
    • 18344396568 scopus 로고    scopus 로고
    • Minimum information about a microarray experiment (MIAME)-toward standards for microarray data
    • Brazma A, Hingamp P, Quackenbush J, SherlockG, Spellman P, et al. 2001. Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat. Genet. 29(4):365-71
    • (2001) Nat. Genet , vol.29 , Issue.4 , pp. 365-371
    • Brazma, A.1    Hingamp, P.2    Quackenbush, J.3    Sherlock, G.4    Spellman, P.5
  • 4
    • 84866162527 scopus 로고    scopus 로고
    • Exposome: Time for transformative research
    • Buck Louis GM, Sundaram R. 2012. Exposome: time for transformative research. Stat. Med. 31(22):2569-75
    • (2012) Stat. Med , vol.31 , Issue.22 , pp. 2569-2575
    • Buck Louis, G.M.1    Sundaram, R.2
  • 6
    • 1842840855 scopus 로고    scopus 로고
    • Toxicokinetic genetics: An approach to gene-environment and gene-gene interactions in complex metabolic pathways
    • Cortessis V, ThomasDC. 2004. Toxicokinetic genetics: an approach to gene-environment and gene-gene interactions in complex metabolic pathways. IARC Sci. Publ. (157):127-50
    • (2004) IARC Sci. Publ , Issue.157 , pp. 127-150
    • Cortessis, V.1    Thomas, D.C.2
  • 7
    • 66149137211 scopus 로고    scopus 로고
    • The preventable causes of death in the United States: Comparative risk assessment of dietary, lifestyle, and metabolic risk factors
    • Danaei G, Ding EL, Mozaffarian D, Taylor B, Rehm J, et al. 2009. The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors. PLOS Med. 6(4):e1000058
    • (2009) PLOS Med , vol.6 , Issue.4 , pp. e1000058
    • Danaei, G.1    Ding, E.L.2    Mozaffarian, D.3    Taylor, B.4    Rehm, J.5
  • 10
    • 77952822074 scopus 로고    scopus 로고
    • PheWAS: Demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations
    • Denny JC, Ritchie MD, Basford MA, Pulley JM, Bastarache L, et al. 2010. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics 26(9):1205-10
    • (2010) Bioinformatics , vol.26 , Issue.9 , pp. 1205-1210
    • Denny, J.C.1    Ritchie, M.D.2    Basford, M.A.3    Pulley, J.M.4    Bastarache, L.5
  • 11
    • 85006931035 scopus 로고    scopus 로고
    • A hybrid model for spatially and temporally resolved ozone exposures in the continental United States
    • Di Q, Rowland S, Koutrakis P, Schwartz J. 2017. A hybrid model for spatially and temporally resolved ozone exposures in the continental United States. J. Air Waste Manag. Assoc. 67:39-52
    • (2017) J. Air Waste Manag. Assoc , vol.67 , pp. 39-52
    • Di, Q.1    Rowland, S.2    Koutrakis, P.3    Schwartz, J.4
  • 12
    • 77249110418 scopus 로고    scopus 로고
    • Protecting human health from air pollution: Shifting from a single-pollutant to a multipollutant approach
    • Dominici F, Peng RD, Barr CD, Bell ML. 2010. Protecting human health from air pollution: shifting from a single-pollutant to a multipollutant approach. Epidemiology 21(2):187-94
    • (2010) Epidemiology , vol.21 , Issue.2 , pp. 187-194
    • Dominici, F.1    Peng, R.D.2    Barr, C.D.3    Bell, M.L.4
  • 13
    • 45849134070 scopus 로고    scopus 로고
    • Sparse inverse covariance estimation with the lasso
    • Friedman J, Hastie T, Tibshirani R. 2007. Sparse inverse covariance estimation with the lasso. Biostatistics 9:432-41
    • (2007) Biostatistics , vol.9 , pp. 432-441
    • Friedman, J.1    Hastie, T.2    Tibshirani, R.3
  • 14
    • 84881611825 scopus 로고    scopus 로고
    • Finding novel genes by testing G×E interactions in a genome-wide association study
    • Gauderman WJ, Zhang P, Morrison JL, Lewinger JP. 2013. Finding novel genes by testing G×E interactions in a genome-wide association study. Genet. Epidemiol. 37(6):603-13
    • (2013) Genet. Epidemiol , vol.37 , Issue.6 , pp. 603-613
    • Gauderman, W.J.1    Zhang, P.2    Morrison, J.L.3    Lewinger, J.P.4
  • 15
    • 33750722797 scopus 로고    scopus 로고
    • From a theoretical framework of human exposure and dose assessment to computational system implementation: TheModeling ENvironment for TOtal Risk Studies (MENTOR)
    • Georgopoulos PG, LioyPJ. 2006. From a theoretical framework of human exposure and dose assessment to computational system implementation: theModeling ENvironment for TOtal Risk Studies (MENTOR). J. Toxicol. Environ. Health. B Crit. Rev. 9(6):457-83
    • (2006) J. Toxicol. Environ. Health. B Crit. Rev , vol.9 , Issue.6 , pp. 457-483
    • Georgopoulos, P.G.1    Lioy, P.J.2
  • 17
    • 84905890259 scopus 로고    scopus 로고
    • Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank
    • Hall MA, Dudek SM, Goodloe R, Crawford DC, Pendergrass SA, et al. 2014. Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank. Pac. Symp. Biocomput. 2014:200-11
    • (2014) Pac. Symp. Biocomput , vol.2014 , pp. 200-211
    • Hall, M.A.1    Dudek, S.M.2    Goodloe, R.3    Crawford, D.C.4    Pendergrass, S.A.5
  • 18
    • 84919624872 scopus 로고    scopus 로고
    • Detection of pleiotropy through a phenome-wide association study (pheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study
    • Hall MA, Verma A, Brown-Gentry KD, Goodloe R, Boston J, et al. 2014. Detection of pleiotropy through a phenome-wide association study (pheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study. PLOS Genet. 10(12):e1004678
    • (2014) PLOS Genet , vol.10 , Issue.12 , pp. e1004678
    • Hall, M.A.1    Verma, A.2    Brown-Gentry, K.D.3    Goodloe, R.4    Boston, J.5
  • 20
    • 84906213269 scopus 로고    scopus 로고
    • WebProtégé: A collaborative Web-based platform for editing biomedical ontologies
    • HorridgeM, TudoracheT, Nuylas C, Vendetti J, NoyNF, MusenMA. 2014. WebProtégé: a collaborative Web-based platform for editing biomedical ontologies. Bioinformatics 30(16):2384-85
    • (2014) Bioinformatics , vol.30 , Issue.16 , pp. 2384-2385
    • Horridge, M.1    Tudorache, T.2    Nuylas, C.3    Vendetti, J.4    Noy, N.F.5    Musen, M.A.6
  • 21
    • 84867614472 scopus 로고    scopus 로고
    • Powerful cocktail methods for detecting genome-wide gene-environment interaction
    • Hsu L, Jiao S, Dai JY, Hutter C, Peters U, Kooperberg C. 2012. Powerful cocktail methods for detecting genome-wide gene-environment interaction. Genet. Epidemiol. 36(3):183-94
    • (2012) Genet. Epidemiol , vol.36 , Issue.3 , pp. 183-194
    • Hsu, L.1    Jiao, S.2    Dai, J.Y.3    Hutter, C.4    Peters, U.5    Kooperberg, C.6
  • 23
    • 77049105601 scopus 로고    scopus 로고
    • Researching genetic versus nongenetic determinants of disease: A comparison and proposed unification
    • Ioannidis JPA, Loy EY, Poulton R, Chia KS. 2009. Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification. Sci. Transl. Med. 1(7):7ps8
    • (2009) Sci. Transl. Med , vol.1 , Issue.7 , pp. 7ps8
    • Ioannidis, J.P.A.1    Loy, E.Y.2    Poulton, R.3    Chia, K.S.4
  • 24
    • 80054769484 scopus 로고    scopus 로고
    • A generic, cross-chemical predictive PBTK model with multiple entry routes running as application inMS Excel; Design of the model and comparison of predictions with experimental results
    • Jongeneelen FJ, Ten Berge WF. 2011. A generic, cross-chemical predictive PBTK model with multiple entry routes running as application inMS Excel; design of the model and comparison of predictions with experimental results. Ann. Occup. Hyg. 55(8):841-64
    • (2011) Ann. Occup. Hyg , vol.55 , Issue.8 , pp. 841-864
    • Jongeneelen, F.J.1    Ten Berge, W.F.2
  • 25
    • 77955144299 scopus 로고    scopus 로고
    • Replication in genome-wide association studies
    • Kraft P, Zeggini E, Ioannidis JPA. 2009. Replication in genome-wide association studies. Stat. Sci. 24(4):561-73
    • (2009) Stat. Sci. , vol.24 , Issue.4 , pp. 561-573
    • Kraft, P.1    Zeggini, E.2    Ioannidis, J.P.A.3
  • 27
    • 60149103126 scopus 로고    scopus 로고
    • Detecting gene-environment interactions using a combined case-only and casecontrol approach
    • Li D, Conti DV. 2009. Detecting gene-environment interactions using a combined case-only and casecontrol approach. Am. J. Epidemiol. 169(4):497-504
    • (2009) Am. J. Epidemiol , vol.169 , Issue.4 , pp. 497-504
    • Li, D.1    Conti, D.V.2
  • 28
    • 80455162391 scopus 로고    scopus 로고
    • Exposure science and the exposome: An opportunity for coherence in the environmental health sciences
    • Lioy PJ, Rappaport SM. 2011. Exposure science and the exposome: an opportunity for coherence in the environmental health sciences. Environ. Health Perspect. 119(11):466-67
    • (2011) Environ. Health Perspect , vol.119 , Issue.11 , pp. 466-467
    • Lioy, P.J.1    Rappaport, S.M.2
  • 29
    • 34748848639 scopus 로고    scopus 로고
    • The NCBI dbGaP database of genotypes and phenotypes
    • Mailman MD, Feolo M, Jin Y, KimuraM, Tryka K, et al. 2007. The NCBI dbGaP database of genotypes and phenotypes. Nat. Genet. 39(10):1181-86
    • (2007) Nat. Genet , vol.39 , Issue.10 , pp. 1181-1186
    • Mailman, M.D.1    Feolo, M.2    Jin, Y.3    Kimura, M.4    Tryka, K.5
  • 33
    • 84891338758 scopus 로고    scopus 로고
    • The nature of nurture: Refining the definition of the exposome
    • Miller GW, Jones DP. 2014. The nature of nurture: refining the definition of the exposome. Toxicol. Sci. 137(1):1-2
    • (2014) Toxicol. Sci. , vol.137 , Issue.1 , pp. 1-2
    • Miller, G.W.1    Jones, D.P.2
  • 34
    • 1542347858 scopus 로고    scopus 로고
    • Actual causes of death in the United States, 2000
    • Mokdad AH, Marks JS, Stroup DF, Gerberding JL. 2004. Actual causes of death in the United States, 2000. JAMA 291(10):1238-45
    • (2004) JAMA , vol.291 , Issue.10 , pp. 1238-1245
    • Mokdad, A.H.1    Marks, J.S.2    Stroup, D.F.3    Gerberding, J.L.4
  • 35
    • 84856181067 scopus 로고    scopus 로고
    • Testing gene-environment interaction in large-scale case-control association studies: Possible choices and comparisons
    • Mukherjee B, Ahn J, Gruber SB, Chatterjee N. 2012. Testing gene-environment interaction in large-scale case-control association studies: possible choices and comparisons. Am. J. Epidemiol. 175(3):177-90
    • (2012) Am. J. Epidemiol , vol.175 , Issue.3 , pp. 177-190
    • Mukherjee, B.1    Ahn, J.2    Gruber, S.B.3    Chatterjee, N.4
  • 36
    • 84901569100 scopus 로고    scopus 로고
    • An efficient and robust method for analyzing population pharmacokinetic data in genome-wide pharmacogenomic studies: A generalized estimating equation approach
    • Nagashima K, Sato Y, Noma H, Hamada C. 2013. An efficient and robust method for analyzing population pharmacokinetic data in genome-wide pharmacogenomic studies: a generalized estimating equation approach. Stat. Med. 32(27):4838-58
    • (2013) Stat. Med , vol.32 , Issue.27 , pp. 4838-4858
    • Nagashima, K.1    Sato, Y.2    Noma, H.3    Hamada, C.4
  • 37
    • 67849128700 scopus 로고    scopus 로고
    • BioPortal: Ontologies and integrated data resources at the click of a mouse
    • Noy NF, Shah NH, Whetzel PL, Dai B, Dorf M, et al. 2009. BioPortal: ontologies and integrated data resources at the click of a mouse. Nucleic Acids Res. 37(Suppl. 2):W170-73
    • (2009) Nucleic Acids Res , vol.37 , Issue.2 , pp. W170-W173
    • Noy, N.F.1    Shah, N.H.2    Whetzel, P.L.3    Dai, B.4    Dorf, M.5
  • 38
    • 77953886372 scopus 로고    scopus 로고
    • An environment-wide association study (EWAS) on type 2 diabetes mellitus
    • Patel CJ, Bhattacharya J, Butte AJ. 2010. An environment-wide association study (EWAS) on type 2 diabetes mellitus. PLOS ONE 5(5):e10746
    • (2010) PLOS ONE , vol.5 , Issue.5 , pp. e10746
    • Patel, C.J.1    Bhattacharya, J.2    Butte, A.J.3
  • 39
    • 84876500725 scopus 로고    scopus 로고
    • Systematic identification of interaction effects between genome-and environment-wide associations in type 2 diabetes mellitus
    • Patel CJ, Chen R, Kodama K, Ioannidis JPA, Butte AJ. 2013. Systematic identification of interaction effects between genome-and environment-wide associations in type 2 diabetes mellitus. Hum. Genet. 132(5):495-508
    • (2013) Hum. Genet , vol.132 , Issue.5 , pp. 495-508
    • Patel, C.J.1    Chen, R.2    Kodama, K.3    Ioannidis, J.P.A.4    Butte, A.J.5
  • 40
    • 84863511620 scopus 로고    scopus 로고
    • Systematic evaluation of environmental factors: Persistent pollutants and nutrients correlated with serum lipid levels
    • Patel CJ, Cullen MR, Ioannidis JPA, Butte AJ. 2012. Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels. Int. J. Epidemiol. 41(3):828-43
    • (2012) Int. J. Epidemiol , vol.41 , Issue.3 , pp. 828-843
    • Patel, C.J.1    Cullen, M.R.2    Ioannidis, J.P.A.3    Butte, A.J.4
  • 41
    • 84911368398 scopus 로고    scopus 로고
    • Placing epidemiological results in the context of multiplicity and typical correlations of exposures
    • Patel CJ, Ioannidis JPA. 2014. Placing epidemiological results in the context of multiplicity and typical correlations of exposures. J. Epidemiol. Community Health 68(11):1096-100
    • (2014) J. Epidemiol. Community Health , vol.68 , Issue.11 , pp. 1096-1100
    • Patel, C.J.1    Ioannidis, J.P.A.2
  • 42
    • 84901759936 scopus 로고    scopus 로고
    • Studying the elusive environment in large scale
    • Patel CJ, Ioannidis JPA. 2014. Studying the elusive environment in large scale. JAMA 311(21):2173-74
    • (2014) JAMA , vol.311 , Issue.21 , pp. 2173-2174
    • Patel, C.J.1    Ioannidis, J.P.A.2
  • 43
    • 84971326365 scopus 로고    scopus 로고
    • Development of exposome correlation globes to map out environment-wide associations
    • Patel CJ, Manrai AK. 2015. Development of exposome correlation globes to map out environment-wide associations. Pac. Symp. Biocomput. 2015:231-42
    • (2015) Pac. Symp. Biocomput , vol.2015 , pp. 231-242
    • Patel, C.J.1    Manrai, A.K.2
  • 44
    • 84992588804 scopus 로고    scopus 로고
    • A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey
    • Patel CJ, Pho N, McDuffie M, Easton-Marks J, Kothari C, et al. 2016. A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey. Sci. Data 3:160096
    • (2016) Sci. Data , vol.3 , pp. 160096
    • Patel, C.J.1    Pho, N.2    McDuffie, M.3    Easton-Marks, J.4    Kothari, C.5
  • 45
    • 79952493624 scopus 로고    scopus 로고
    • QSARs for PBPK modelling of environmental contaminants
    • Peyret T, Krishnan K. 2011. QSARs for PBPK modelling of environmental contaminants. SAR QSAR Environ. Res. 22(1-2):129-69
    • (2011) SAR QSAR Environ. Res , vol.22 , Issue.1-2 , pp. 129-169
    • Peyret, T.1    Krishnan, K.2
  • 46
    • 84933279742 scopus 로고    scopus 로고
    • Meta-analysis of the heritability of human traits based on fifty years of twin studies
    • Polderman TJC, Benyamin B, Leeuw CA, Sullivan PF, van Bochoven A, et al. 2015. Meta-analysis of the heritability of human traits based on fifty years of twin studies. Nat. Genet. 47(7):702-9
    • (2015) Nat. Genet , vol.47 , Issue.7 , pp. 702-709
    • Polderman, T.J.C.1    Benyamin, B.2    Leeuw, C.A.3    Sullivan, P.F.4    Van Bochoven, A.5
  • 47
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. 2006. Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet. 38(8):904-9
    • (2006) Nat. Genet , vol.38 , Issue.8 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 48
    • 79952494531 scopus 로고    scopus 로고
    • An integrated QSAR-PBPK modelling approach for predicting the inhalation toxicokinetics of mixtures of volatile organic chemicals in the rat
    • Price K, Krishnan K. 2011. An integrated QSAR-PBPK modelling approach for predicting the inhalation toxicokinetics of mixtures of volatile organic chemicals in the rat. SAR QSAR Environ. Res. 22(1-2):107-28
    • (2011) SAR QSAR Environ. Res , vol.22 , Issue.1-2 , pp. 107-128
    • Price, K.1    Krishnan, K.2
  • 49
    • 34548292504 scopus 로고    scopus 로고
    • Plink: A tool set for wholegenome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, et al. 2007. Plink: a tool set for wholegenome association and population-based linkage analyses. Am. J. Hum. Genet. 81(3):559-75
    • (2007) Am. J. Hum. Genet , vol.81 , Issue.3 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.R.5
  • 50
    • 84977644984 scopus 로고    scopus 로고
    • Genetic factors are not the major causes of chronic diseases
    • Rappaport SM. 2016. Genetic factors are not the major causes of chronic diseases. PLOS ONE 11(4):e0154387
    • (2016) PLOS ONE , vol.11 , Issue.4 , pp. e0154387
    • Rappaport, S.M.1
  • 52
    • 77958192172 scopus 로고    scopus 로고
    • Environment and disease risks
    • Rappaport SM, Smith MT. 2010. Environment and disease risks. Science 330:460-61
    • (2010) Science , vol.330 , pp. 460-461
    • Rappaport, S.M.1    Smith, M.T.2
  • 53
    • 80051690360 scopus 로고    scopus 로고
    • A computational framework for aggregate and cumulative exposure assessment
    • Sarigiannis D, Gotti A, Karakitsios S. 2011. A computational framework for aggregate and cumulative exposure assessment. Epidemiology 22:96-97
    • (2011) Epidemiology , vol.22 , pp. 96-97
    • Sarigiannis, D.1    Gotti, A.2    Karakitsios, S.3
  • 54
    • 73949113353 scopus 로고    scopus 로고
    • Reflections on new directions for risk assessment of environmental chemical mixtures
    • Sarigiannis D, Gotti A, Reale GC, Marafante E. 2009. Reflections on new directions for risk assessment of environmental chemical mixtures. Int. J. Risk Assess. Manag. 13:216
    • (2009) Int. J. Risk Assess. Manag , vol.13 , pp. 216
    • Sarigiannis, D.1    Gotti, A.2    Reale, G.C.3    Marafante, E.4
  • 55
    • 35948989284 scopus 로고    scopus 로고
    • The OBO foundry: Coordinated evolution of ontologies to support biomedical data integration
    • Smith B, Ashburner M, Rosse C, Bard J, Bug W, et al. 2007. The OBO foundry: coordinated evolution of ontologies to support biomedical data integration. Nat. Biotechnol. 25(11):1251-55
    • (2007) Nat. Biotechnol , vol.25 , Issue.11 , pp. 1251-1255
    • Smith, B.1    Ashburner, M.2    Rosse, C.3    Bard, J.4    Bug, W.5
  • 56
    • 85017186987 scopus 로고    scopus 로고
    • updated July 12
    • SNPedia. 2014. Heritability. SNPedia, updated July 12 http://www.snpedia.com/index.php/ Heritability
    • (2014) Heritability. SNPedia
  • 57
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. 2005. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. PNAS 102(43):15545-50
    • (2005) PNAS , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5
  • 58
    • 84886541634 scopus 로고    scopus 로고
    • Statistical strategies for constructing health risk models with multiple pollutants and their interactions: Possible choices and comparisons
    • Sun Z, Tao Y, Li S, Ferguson KK, Meeker JD, et al. 2013. Statistical strategies for constructing health risk models with multiple pollutants and their interactions: possible choices and comparisons. Environ. Health 12(1):85
    • (2013) Environ. Health , vol.12 , Issue.1 , pp. 85
    • Sun, Z.1    Tao, Y.2    Li, S.3    Ferguson, K.K.4    Meeker, J.D.5
  • 59
    • 77949772292 scopus 로고    scopus 로고
    • Gene-environment-wide association studies: Emerging approaches
    • Thomas D. 2010. Gene-environment-wide association studies: emerging approaches. Nat. Rev. Genet. 11(4):259-72
    • (2010) Nat. Rev. Genet , vol.11 , Issue.4 , pp. 259-272
    • Thomas, D.1
  • 60
    • 0024217358 scopus 로고
    • Models for exposure-time-response relationships with applications to cancer epidemiology
    • Thomas DC. 1988. Models for exposure-time-response relationships with applications to cancer epidemiology. Annu. Rev. Public Health 9:451-82
    • (1988) Annu. Rev. Public Health , vol.9 , pp. 451-482
    • Thomas, D.C.1
  • 61
    • 85018193775 scopus 로고    scopus 로고
    • Assessing the exposome with external measures: Commentary on the state of the science and research recommendations
    • Turner M, Nieuwenhuijsen M, Anderson K, Balshaw D, Cui Y, et al. 2017. Assessing the exposome with external measures: commentary on the state of the science and research recommendations. Annu. Rev. Public Health 38:215-39
    • (2017) Annu. Rev. Public Health , vol.38 , pp. 215-239
    • Turner, M.1    Nieuwenhuijsen, M.2    Anderson, K.3    Balshaw, D.4    Cui, Y.5
  • 62
    • 84869876493 scopus 로고    scopus 로고
    • A nutrient-wide association study on blood pressure
    • Tzoulaki I, Patel CJ, Okamura T, Chan Q, Brown IJ, et al. 2012. A nutrient-wide association study on blood pressure. Circulation 126(21):2456-64
    • (2012) Circulation , vol.126 , Issue.21 , pp. 2456-2464
    • Tzoulaki, I.1    Patel, C.J.2    Okamura, T.3    Chan, Q.4    Brown, I.J.5
  • 63
    • 85006671057 scopus 로고    scopus 로고
    • Updated Sept. 22, US EPA, Washington, DC
    • US EPA (US Environ. Prot. Agency). 2014. Toxic Substances Control Act (TSCA) search. Updated Sept. 22, US EPA, Washington, DC. http://www.epa.gov/enviro/facts/tsca/tsca-search.html
    • (2014) Toxic Substances Control Act (TSCA) Search
  • 65
  • 66
    • 0001880068 scopus 로고    scopus 로고
    • The Bayesian analysis of population pharmacokineticmodels
    • Wakefield J. 1996. The Bayesian analysis of population pharmacokineticmodels. J. Am. Stat. Assoc. 91:62-75
    • (1996) J. Am. Stat. Assoc , vol.91 , pp. 62-75
    • Wakefield, J.1
  • 67
    • 84891790401 scopus 로고    scopus 로고
    • The NHGRIGWASCatalog, a curated resource of SNP-trait associations
    • Welter D, MacArthur J, Morales J, Burdett T, Hall P, et al. 2014. The NHGRIGWASCatalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42(1):D1001-6
    • (2014) Nucleic Acids Res , vol.42 , Issue.1 , pp. D1001-D1006
    • Welter, D.1    MacArthur, J.2    Morales, J.3    Burdett, T.4    Hall, P.5
  • 68
    • 23844523425 scopus 로고    scopus 로고
    • Complementing the genome with an "exposome": The outstanding challenge of environmental exposuremeasurement in molecular epidemiology
    • Wild CP. 2005. Complementing the genome with an "exposome": the outstanding challenge of environmental exposuremeasurement in molecular epidemiology. Cancer Epidemiol. Biomarkers Prev. 14(8):1847-50
    • (2005) Cancer Epidemiol. Biomarkers Prev , vol.14 , Issue.8 , pp. 1847-1850
    • Wild, C.P.1
  • 69
    • 84858668898 scopus 로고    scopus 로고
    • The exposome: From concept to utility
    • Wild CP. 2012. The exposome: from concept to utility. Int. J. Epidemiol. 41(1):24-32
    • (2012) Int. J. Epidemiol , vol.41 , Issue.1 , pp. 24-32
    • Wild, C.P.1
  • 72
    • 0033947604 scopus 로고    scopus 로고
    • Exposure measurement error in time-series studies of air pollution: Concepts and consequences
    • Zeger SL, Thomas D, Dominici F, Samet JM, Schwartz J, et al. 2000. Exposure measurement error in time-series studies of air pollution: concepts and consequences. Environ. Health Perspect. 108(5):419-26
    • (2000) Environ. Health Perspect , vol.108 , Issue.5 , pp. 419-426
    • Zeger, S.L.1    Thomas, D.2    Dominici, F.3    Samet, J.M.4    Schwartz, J.5
  • 73
    • 16244401458 scopus 로고    scopus 로고
    • Regularization and variable selection via the elastic net
    • ZouH, HastieT. 2005. Regularization and variable selection via the elastic net. J. R. Stat. Soc. B 67(2):301-20
    • (2005) J. R. Stat. Soc. B , vol.67 , Issue.2 , pp. 301-320
    • Zou, H.1    Hastie, T.2


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