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Volumn 8, Issue MAR, 2017, Pages

Exosomes isolated from ascites of T-cell lymphoma-bearing mice expressing surface CD24 and HSP-90 induce a tumor-specific immune response

Author keywords

Ascites; Exosomes; Immune response; T cell lymphoma; Tumor vaccine

Indexed keywords

ALIX PROTEIN; CARBOXYFLUORESCEIN SUCCINIMIDYL ESTER; CD24 ANTIGEN; CD63 ANTIGEN; CD81 ANTIGEN; CD9 ANTIGEN; FLUORESCENT DYE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; PEPTIDES AND PROTEINS; TETRASPANIN; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; TUMOR VACCINE; UNCLASSIFIED DRUG;

EID: 85017184464     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00286     Document Type: Article
Times cited : (51)

References (41)
  • 1
    • 84877585949 scopus 로고    scopus 로고
    • Extracellular vesicles: biology and emerging therapeutic opportunities
    • El Andaloussi S, Mäger I, Breakefield XO, Wood MJ. Extracellular vesicles: biology and emerging therapeutic opportunities. Nat Rev Drug Discov (2013) 12:347-57. doi: 10.1038/nrd3978
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 347-357
    • El Andaloussi, S.1    Mäger, I.2    Breakefield, X.O.3    Wood, M.J.4
  • 2
    • 84904704297 scopus 로고    scopus 로고
    • Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
    • Colombo M, Raposo G, Théry C. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol (2014) 30:255-89. doi:10.1146/annurev-cellbio-101512-122326
    • (2014) Annu Rev Cell Dev Biol , vol.30 , pp. 255-289
    • Colombo, M.1    Raposo, G.2    Théry, C.3
  • 3
    • 84959386845 scopus 로고    scopus 로고
    • Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
    • Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci U S A (2016) 113:E968-77. doi:10.1073/pnas.1521230113
    • (2016) Proc Natl Acad Sci U S A , vol.113 , pp. E968-E977
    • Kowal, J.1    Arras, G.2    Colombo, M.3    Jouve, M.4    Morath, J.P.5    Primdal-Bengtson, B.6
  • 4
    • 84934270711 scopus 로고    scopus 로고
    • Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications
    • De Toro J, Herschlik L, Waldner C, Mongini C. Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications. Front Immunol (2015) 6:203. doi:10.3389/fimmu.2015.00203
    • (2015) Front Immunol , vol.6 , pp. 203
    • De Toro, J.1    Herschlik, L.2    Waldner, C.3    Mongini, C.4
  • 5
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell (2011) 144:646-74. doi:10.1016/j.cell.2011.02.013
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 84879603171 scopus 로고    scopus 로고
    • Exosomes in tumor microenvironment influence cancer progression and metastasis
    • Kahlert C, Kalluri R. Exosomes in tumor microenvironment influence cancer progression and metastasis. J Mol Med (2013) 91:431-7. doi:10.1007/s00109-013-1020-6
    • (2013) J Mol Med , vol.91 , pp. 431-437
    • Kahlert, C.1    Kalluri, R.2
  • 7
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • Kucharzewska P, Christianson HC, Welch JE, Svensson KJ, Fredlund E, Ringnér M, et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci U S A (2013) 110:7312-7. doi:10.1073/pnas.1220998110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 7312-7317
    • Kucharzewska, P.1    Christianson, H.C.2    Welch, J.E.3    Svensson, K.J.4    Fredlund, E.5    Ringnér, M.6
  • 8
    • 78649958307 scopus 로고    scopus 로고
    • Cancer exosomes trigger fibroblast to myofibroblast differentiation
    • Webber J, Steadman R, Mason MD, Tabi Z, Clayton A. Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Res (2010) 70:9621-30. doi:10.1158/0008-5472.CAN-10-1722
    • (2010) Cancer Res , vol.70 , pp. 9621-9630
    • Webber, J.1    Steadman, R.2    Mason, M.D.3    Tabi, Z.4    Clayton, A.5
  • 9
    • 84896818399 scopus 로고    scopus 로고
    • Regulation of immune responses by extracellular vesicles
    • Robbins PD, Morelli AE. Regulation of immune responses by extracellular vesicles. Nat Rev Immunol (2014) 14:195-208. doi:10.1038/nri3622
    • (2014) Nat Rev Immunol , vol.14 , pp. 195-208
    • Robbins, P.D.1    Morelli, A.E.2
  • 10
    • 24644435853 scopus 로고    scopus 로고
    • Dexosomes as a therapeutic cancer vaccine: from bench to bedside
    • Le Pecq J-B. Dexosomes as a therapeutic cancer vaccine: from bench to bedside. Blood Cells Mol Dis (2005) 35:129-35. doi:10.1016/j.bcmd.2005.06.003
    • (2005) Blood Cells Mol Dis , vol.35 , pp. 129-135
    • Le Pecq, J.-B.1
  • 11
    • 24644524011 scopus 로고    scopus 로고
    • Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis
    • Abusamra AJ, Zhong Z, Zheng X, Li M, Ichim TE, Chin JL, et al. Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis. Blood Cells Mol Dis (2005) 35:169-73. doi:10.1016/j.bcmd.2005.07.001
    • (2005) Blood Cells Mol Dis , vol.35 , pp. 169-173
    • Abusamra, A.J.1    Zhong, Z.2    Zheng, X.3    Li, M.4    Ichim, T.E.5    Chin, J.L.6
  • 12
    • 61849139471 scopus 로고    scopus 로고
    • Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells
    • Klibi J, Niki T, Riedel A, Pioche-Durieu C, Souquere S, Rubinstein E, et al. Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells. Blood (2009) 113:1957-66. doi:10.1182/blood-2008-02-142596
    • (2009) Blood , vol.113 , pp. 1957-1966
    • Klibi, J.1    Niki, T.2    Riedel, A.3    Pioche-Durieu, C.4    Souquere, S.5    Rubinstein, E.6
  • 13
  • 14
    • 34547686145 scopus 로고    scopus 로고
    • Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2
    • Clayton A, Mitchell JP, Court J, Mason MD, Tabi Z. Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2. Cancer Res (2007) 67:7458-66. doi:10.1158/0008-5472.CAN-06-3456
    • (2007) Cancer Res , vol.67 , pp. 7458-7466
    • Clayton, A.1    Mitchell, J.P.2    Court, J.3    Mason, M.D.4    Tabi, Z.5
  • 15
    • 31144451576 scopus 로고    scopus 로고
    • Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function
    • Liu C, Yu S, Zinn K, Wang J, Zhang L, Jia Y, et al. Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function. J Immunol (2006) 176:1375-85. doi:10.4049/jimmunol.176.3.1375
    • (2006) J Immunol , vol.176 , pp. 1375-1385
    • Liu, C.1    Yu, S.2    Zinn, K.3    Wang, J.4    Zhang, L.5    Jia, Y.6
  • 16
    • 77955406553 scopus 로고    scopus 로고
    • Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg)
    • Szajnik M, Czystowska M, Szczepanski MJ, Mandapathil M, Whiteside TL. Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg). PLoS One (2010) 5:e11469. doi:10.1371/journal.pone.0011469
    • (2010) PLoS One , vol.5
    • Szajnik, M.1    Czystowska, M.2    Szczepanski, M.J.3    Mandapathil, M.4    Whiteside, T.L.5
  • 17
    • 79955548092 scopus 로고    scopus 로고
    • Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC
    • Battke C, Ruiss R, Welsch U, Wimberger P, Lang S, Jochum S, et al. Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC. Cancer Immunol Immunother (2011) 60(5):639-48. doi:10.1007/s00262-011-0979-5
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.5 , pp. 639-648
    • Battke, C.1    Ruiss, R.2    Welsch, U.3    Wimberger, P.4    Lang, S.5    Jochum, S.6
  • 18
    • 18144369346 scopus 로고    scopus 로고
    • A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
    • Morse MA, Garst J, Osada T, Khan S, Hobeika A, Clay TM, et al. A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer. J Transl Med (2005) 3:9. doi:10.1186/1479-5876-3-9
    • (2005) J Transl Med , vol.3 , pp. 9
    • Morse, M.A.1    Garst, J.2    Osada, T.3    Khan, S.4    Hobeika, A.5    Clay, T.M.6
  • 19
    • 41149172340 scopus 로고    scopus 로고
    • Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
    • Dai S, Wei D, Wu Z, Zhou X, Wei X, Huang H, et al. Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer. Mol Ther (2008) 16:782-90. doi:10.1038/mt.2008.1
    • (2008) Mol Ther , vol.16 , pp. 782-790
    • Dai, S.1    Wei, D.2    Wu, Z.3    Zhou, X.4    Wei, X.5    Huang, H.6
  • 20
    • 70350593773 scopus 로고    scopus 로고
    • Exosomes in tumour immunity
    • Clayton A, Mason MD. Exosomes in tumour immunity. Curr Oncol (2009) 16:46-9. doi:10.3747/co.v16i3.367
    • (2009) Curr Oncol , vol.16 , pp. 46-49
    • Clayton, A.1    Mason, M.D.2
  • 21
    • 33746944049 scopus 로고    scopus 로고
    • BCR-bound antigen is targeted to exosomes in human follicular lymphoma B-cells
    • Rialland P, Lankar D, Raposo G, Bonnerot C, Hubert P. BCR-bound antigen is targeted to exosomes in human follicular lymphoma B-cells. Biol Cell (2006) 98:491-501. doi:10.1042/BC20060027
    • (2006) Biol Cell , vol.98 , pp. 491-501
    • Rialland, P.1    Lankar, D.2    Raposo, G.3    Bonnerot, C.4    Hubert, P.5
  • 22
    • 80053067140 scopus 로고    scopus 로고
    • Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3
    • Aung T, Chapuy B, Vogel D, Wenzel D, Oppermann M, Lahmann M, et al. Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3. Proc Natl Acad Sci U S A (2011) 108:15336-41. doi:10.1073/pnas.1102855108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 15336-15341
    • Aung, T.1    Chapuy, B.2    Vogel, D.3    Wenzel, D.4    Oppermann, M.5    Lahmann, M.6
  • 23
    • 79251581240 scopus 로고    scopus 로고
    • Exosomes containing glycoprotein 350 released by EBV-transformed B cells selectively target B cells through CD21 and block EBV infection in vitro
    • Vallhov H, Gutzeit C, Johansson SM, Nagy N, Paul M, Li Q, et al. Exosomes containing glycoprotein 350 released by EBV-transformed B cells selectively target B cells through CD21 and block EBV infection in vitro. J Immunol (2011) 186:73-82. doi:10.4049/jimmunol.1001145
    • (2011) J Immunol , vol.186 , pp. 73-82
    • Vallhov, H.1    Gutzeit, C.2    Johansson, S.M.3    Nagy, N.4    Paul, M.5    Li, Q.6
  • 24
    • 0034761734 scopus 로고    scopus 로고
    • Characterization of the immunophenotype and the metastatic properties of a murine T-lymphoma cell line. Unexpected expression of cytoplasmatic CD4
    • Mongini C, Ruybal P, Gravisaco MJ, Croci M, Sánchez Lockhart M, Fabris V, et al. Characterization of the immunophenotype and the metastatic properties of a murine T-lymphoma cell line. Unexpected expression of cytoplasmatic CD4. In Vitro Cell Dev Biol Anim (2001) 37:499-504. doi:10.1290/1071-2690(2001)037<0499:COTIAT>2.0.CO;2
    • (2001) In Vitro Cell Dev Biol Anim , vol.37 , pp. 499-504
    • Mongini, C.1    Ruybal, P.2    Gravisaco, M.J.3    Croci, M.4    Sánchez Lockhart, M.5    Fabris, V.6
  • 25
    • 42749085108 scopus 로고    scopus 로고
    • Isolation and characterization of exosomes from cell culture supernatants
    • Théry C, Amigorena S, Raposo G, Clayton A. Isolation and characterization of exosomes from cell culture supernatants. Curr Protoc Cell Biol (2006) 3.22.1-3.22.29. doi:10.1002/0471143030.cb0322s30
    • (2006) Curr Protoc Cell Biol , pp. 3.22.1-3.22.29
    • Théry, C.1    Amigorena, S.2    Raposo, G.3    Clayton, A.4
  • 26
    • 0035166047 scopus 로고    scopus 로고
    • Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry
    • Clayton A, Court J, Navabi H, Adams M, Mason MD, Hobot JA, et al. Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry. J Immunol Methods (2001) 247:163-74. doi:10.1016/S0022-1759(00)00321-5
    • (2001) J Immunol Methods , vol.247 , pp. 163-174
    • Clayton, A.1    Court, J.2    Navabi, H.3    Adams, M.4    Mason, M.D.5    Hobot, J.A.6
  • 28
    • 78650569511 scopus 로고    scopus 로고
    • A novel Salmonella typhi-based immunotherapy promotes tumor killing via an antitumor Th1-type cellular immune response and neutrophil activation in a mouse model of breast cancer
    • Vendrell A, Gravisaco MJ, Pasetti MF, Croci M, Colombo L, Rodríguez C, et al. A novel Salmonella typhi-based immunotherapy promotes tumor killing via an antitumor Th1-type cellular immune response and neutrophil activation in a mouse model of breast cancer. Vaccine (2011) 29:728-36. doi:10.1016/j.vaccine.2010.11.017
    • (2011) Vaccine , vol.29 , pp. 728-736
    • Vendrell, A.1    Gravisaco, M.J.2    Pasetti, M.F.3    Croci, M.4    Colombo, L.5    Rodríguez, C.6
  • 29
    • 37649021448 scopus 로고    scopus 로고
    • Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester
    • Quah BJC, Warren HS, Parish CR. Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester. Nat Protoc (2007) 2:2049-56. doi:10.1038/nprot.2007.296
    • (2007) Nat Protoc , vol.2 , pp. 2049-2056
    • Quah, B.J.C.1    Warren, H.S.2    Parish, C.R.3
  • 30
    • 34347232370 scopus 로고    scopus 로고
    • Intracellular cytokine optimization and standard operating procedure
    • Lamoreaux L, Roederer M, Koup R. Intracellular cytokine optimization and standard operating procedure. Nat Protoc (2006) 1:1507-16. doi:10.1038/nprot.2006.268
    • (2006) Nat Protoc , vol.1 , pp. 1507-1516
    • Lamoreaux, L.1    Roederer, M.2    Koup, R.3
  • 32
    • 84949934993 scopus 로고    scopus 로고
    • As we wait: coping with an imperfect nomenclature for extracellular vesicles
    • Gould SJ, Raposo G. As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles (2013) 2:20389-91. doi:10.3402/jev.v2i0.20389
    • (2013) J Extracell Vesicles , vol.2 , pp. 20389-20391
    • Gould, S.J.1    Raposo, G.2
  • 33
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: composition, biogenesis and function
    • Théry C, Zitvogel L, Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol (2002) 2:569-79. doi:10.1038/nri855
    • (2002) Nat Rev Immunol , vol.2 , pp. 569-579
    • Théry, C.1    Zitvogel, L.2    Amigorena, S.3
  • 35
    • 28344447457 scopus 로고    scopus 로고
    • CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis
    • Baumann P, Cremers N, Kroese F, Orend G, Chiquet-Ehrismann R, Uede T, et al. CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis. Cancer Res (2005) 65:10783-93. doi:10.1158/0008-5472.CAN-05-0619
    • (2005) Cancer Res , vol.65 , pp. 10783-10793
    • Baumann, P.1    Cremers, N.2    Kroese, F.3    Orend, G.4    Chiquet-Ehrismann, R.5    Uede, T.6
  • 36
    • 24944495594 scopus 로고    scopus 로고
    • Induction of heat shock proteins in B-cell exosomes
    • Clayton A, Turkes A, Navabi H, Mason MD, Tabi Z. Induction of heat shock proteins in B-cell exosomes. J Cell Sci (2005) 118:3631-8. doi:10.1242/jcs.02494
    • (2005) J Cell Sci , vol.118 , pp. 3631-3638
    • Clayton, A.1    Turkes, A.2    Navabi, H.3    Mason, M.D.4    Tabi, Z.5
  • 37
    • 84874377202 scopus 로고    scopus 로고
    • Extracellular vesicles: exosomes, microvesicles, and friends
    • Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol (2013) 200:373-83. doi:10.1083/jcb.201211138
    • (2013) J Cell Biol , vol.200 , pp. 373-383
    • Raposo, G.1    Stoorvogel, W.2
  • 38
    • 0037443410 scopus 로고    scopus 로고
    • Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo
    • Skokos D, Botros HG, Demeure C, Morin J, Peronet R, Birkenmeier G, et al. Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J Immunol (2003) 170:3037-45. doi:10.4049/jimmunol.170.6.3037
    • (2003) J Immunol , vol.170 , pp. 3037-3045
    • Skokos, D.1    Botros, H.G.2    Demeure, C.3    Morin, J.4    Peronet, R.5    Birkenmeier, G.6
  • 39
    • 34249650184 scopus 로고    scopus 로고
    • Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications
    • Spisek R, Charalambous A, Mazumder A, Vesole HD, Jagannath S, Dhodapkar VM. Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications. Blood (2007) 109:4839-45. doi:10.1182/blood-2006-10054221
    • (2007) Blood , vol.109 , pp. 4839-4845
    • Spisek, R.1    Charalambous, A.2    Mazumder, A.3    Vesole, H.D.4    Jagannath, S.5    Dhodapkar, V.M.6
  • 40
    • 84891138385 scopus 로고    scopus 로고
    • Getting to know ovarian cancer ascites: opportunities for targeted therapy-based translational research
    • Ahmed N, Stenvers KL. Getting to know ovarian cancer ascites: opportunities for targeted therapy-based translational research. Front Oncol (2013) 3:256. doi:10.3389/fonc.2013.00256
    • (2013) Front Oncol , vol.3 , pp. 256
    • Ahmed, N.1    Stenvers, K.L.2
  • 41
    • 0037183242 scopus 로고    scopus 로고
    • Malignant effusions and immunogenic tumour-derived exosomes
    • Andre F, Schartz NEC, Movassagh M, Flament C, Pautier P, Morice P, et al. Malignant effusions and immunogenic tumour-derived exosomes. Lancet (2002) 360:295-305. doi:10.1016/S0140-6736(02)09552-1
    • (2002) Lancet , vol.360 , pp. 295-305
    • Andre, F.1    Schartz, N.E.C.2    Movassagh, M.3    Flament, C.4    Pautier, P.5    Morice, P.6


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