Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: A potential link of inflammation to TTP

Blood

Volumn 128, Issue 1, 2016, Pages 110-119

  Pillai, Vikram G ^a   Bao, Jialing ^b   Zander, Catherine B ^a   McDaniel, Jenny K ^c   Chetty, Palaniappan S ^b   Seeholzer, Steven H ^b   Bdeir, Khalil ^d   Cines, Douglas B ^d   Zheng, X Long ^a  

^a University of Alabama at Birmingham   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c CHILDREN S HOSPITAL OF ALABAMA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN NEUTROPHIL PEPTIDE; HUMAN NEUTROPHIL PEPTIDE 1; HUMAN NEUTROPHIL PEPTIDE 2; HUMAN NEUTROPHIL PEPTIDE 3; PEPTIDE; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; ADAMTS13 PROTEIN, HUMAN; DEFENSIN;

ADULT; AGED; ARTICLE; BINDING AFFINITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION; INFLAMMATION; LEUKOCYTE ACTIVATION; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN MOTIF; THROMBOTIC THROMBOCYTOPENIC PURPURA; UMBILICAL VEIN ENDOTHELIAL CELL; FEMALE; MALE; METABOLISM; PATHOLOGY;

ADAMTS13 PROTEIN; AMINO ACID MOTIFS; DEFENSINS; FEMALE; HUMANS; INFLAMMATION; MALE; NEUTROPHILS; PROTEOLYSIS; PURPURA, THROMBOTIC THROMBOCYTOPENIC; VON WILLEBRAND FACTOR;

EID: 85017169206     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-12-688747     Document Type: Article

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