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Volumn 272, Issue 6, 2020, Pages 1080-1085

APC and PIK3CA Mutational Cooperativity Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colorectal Liver Metastases

Author keywords

APC; colorectal liver metastases; mutational; PIK3CA

Indexed keywords

ANTINEOPLASTIC AGENT; APC PROTEIN; APC PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PIK3CA PROTEIN, HUMAN;

EID: 85017142145     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0000000000002245     Document Type: Article
Times cited : (28)

References (25)
  • 1
    • 68949094312 scopus 로고    scopus 로고
    • Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
    • Kopetz S, Chang GJ, Overman MJ,. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 2009; 27: 3677-3683.
    • (2009) J Clin Oncol , vol.27 , pp. 3677-3683
    • Kopetz, S.1    Chang, G.J.2    Overman, M.J.3
  • 2
    • 56749096759 scopus 로고    scopus 로고
    • Pathologic response to preoperative chemotherapy: A new outcome end point after resection of hepatic colorectal metastases
    • Blazer DG 3rd, Kishi Y, Maru DM,. Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. J Clin Oncol 2008; 26: 5344-5351.
    • (2008) J Clin Oncol , vol.26 , pp. 5344-5351
    • Blazer, D.G.1    Kishi, Y.2    Maru, D.M.3
  • 3
    • 33847333193 scopus 로고    scopus 로고
    • Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery
    • Rubbia-Brandt L, Giostra E, Brezault C,. Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery. Ann Oncol 2007; 18: 299-304.
    • (2007) Ann Oncol , vol.18 , pp. 299-304
    • Rubbia-Brandt, L.1    Giostra, E.2    Brezault, C.3
  • 4
    • 84884493477 scopus 로고    scopus 로고
    • RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases
    • Vauthey JN, Zimmitti G, Kopetz SE,. RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases. Ann Surg 2013; 258: 619-626.
    • (2013) Ann Surg , vol.258 , pp. 619-626
    • Vauthey, J.N.1    Zimmitti, G.2    Kopetz, S.E.3
  • 5
    • 84939251514 scopus 로고    scopus 로고
    • Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases
    • Brudvik KW, Kopetz SE, Li L,. Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases. Br J Surg 2015; 102: 1175-1183.
    • (2015) Br J Surg , vol.102 , pp. 1175-1183
    • Brudvik, K.W.1    Kopetz, S.E.2    Li, L.3
  • 6
    • 84998854236 scopus 로고    scopus 로고
    • Mutation location on the RAS oncogene affects pathologic features and survival after resection of colorectal liver metastases
    • Frankel TL, Vakiani E, Nathan H,. Mutation location on the RAS oncogene affects pathologic features and survival after resection of colorectal liver metastases. Cancer 2016; 123: 568-575.
    • (2016) Cancer , vol.123 , pp. 568-575
    • Frankel, T.L.1    Vakiani, E.2    Nathan, H.3
  • 7
    • 84930865716 scopus 로고    scopus 로고
    • BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection
    • Schirripa M, Bergamo F, Cremolini C,. BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection. Br J Cancer 2015; 112: 1921-1928.
    • (2015) Br J Cancer , vol.112 , pp. 1921-1928
    • Schirripa, M.1    Bergamo, F.2    Cremolini, C.3
  • 8
    • 84899645301 scopus 로고    scopus 로고
    • PIK3CA and APC mutations are synergistic in the development of intestinal cancers
    • Deming DA, Leystra AA, Nettekoven L,. PIK3CA and APC mutations are synergistic in the development of intestinal cancers. Oncogene 2014; 33: 2245-2254.
    • (2014) Oncogene , vol.33 , pp. 2245-2254
    • Deming, D.A.1    Leystra, A.A.2    Nettekoven, L.3
  • 9
    • 84894263520 scopus 로고    scopus 로고
    • Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice
    • Hare LM, Phesse TJ, Waring PM,. Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice. Biochem J 2014; 458: 251-258.
    • (2014) Biochem J , vol.458 , pp. 251-258
    • Hare, L.M.1    Phesse, T.J.2    Waring, P.M.3
  • 10
    • 11144358645 scopus 로고    scopus 로고
    • High frequency of mutations of the PIK3CA gene in human cancers
    • Samuels Y, Wang Z, Bardelli A,. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004; 304: 554.
    • (2004) Science , vol.304 , pp. 554
    • Samuels, Y.1    Wang, Z.2    Bardelli, A.3
  • 11
    • 77955277111 scopus 로고    scopus 로고
    • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
    • De Roock W, Claes B, Bernasconi D,. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010; 11: 753-762.
    • (2010) Lancet Oncol , vol.11 , pp. 753-762
    • De Roock, W.1    Claes, B.2    Bernasconi, D.3
  • 12
    • 84882289495 scopus 로고    scopus 로고
    • Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes
    • Singh RR, Patel KP, Routbort MJ,. Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes. J Mol Diagn 2013; 15: 607-622.
    • (2013) J Mol Diagn , vol.15 , pp. 607-622
    • Singh, R.R.1    Patel, K.P.2    Routbort, M.J.3
  • 13
    • 0033504042 scopus 로고    scopus 로고
    • Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: Analysis of 1001 consecutive cases
    • Fong Y, Fortner J, Sun RL,. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg 1999; 230: 309-318.
    • (1999) Ann Surg , vol.230 , pp. 309-318
    • Fong, Y.1    Fortner, J.2    Sun, R.L.3
  • 14
    • 84883680951 scopus 로고    scopus 로고
    • Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
    • Douillard JY, Oliner KS, Siena S,. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013; 369: 1023-1034.
    • (2013) N Engl J Med , vol.369 , pp. 1023-1034
    • Douillard, J.Y.1    Oliner, K.S.2    Siena, S.3
  • 15
    • 70349939382 scopus 로고    scopus 로고
    • Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer
    • Siena S, Sartore-Bianchi A, Di Nicolantonio F,. Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. J Natl Cancer Inst 2009; 101: 1308-1324.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1308-1324
    • Siena, S.1    Sartore-Bianchi, A.2    Di Nicolantonio, F.3
  • 16
    • 52749099497 scopus 로고    scopus 로고
    • Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
    • Linardou H, Dahabreh IJ, Kanaloupiti D,. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 2008; 9: 962-972.
    • (2008) Lancet Oncol , vol.9 , pp. 962-972
    • Linardou, H.1    Dahabreh, I.J.2    Kanaloupiti, D.3
  • 17
    • 84924934023 scopus 로고    scopus 로고
    • RAS mutations predict radiologic and pathologic response in patients treated with chemotherapy before resection of colorectal liver metastases
    • Mise Y, Zimmitti G, Shindoh J,. RAS mutations predict radiologic and pathologic response in patients treated with chemotherapy before resection of colorectal liver metastases. Ann Surg Oncol 2015; 22: 834-842.
    • (2015) Ann Surg Oncol , vol.22 , pp. 834-842
    • Mise, Y.1    Zimmitti, G.2    Shindoh, J.3
  • 18
    • 84975454707 scopus 로고    scopus 로고
    • RAS mutation is associated with decreased survival in patients undergoing repeat hepatectomy for colorectal liver metastases
    • Denbo JW, Yamashita S, Passot G,. RAS mutation is associated with decreased survival in patients undergoing repeat hepatectomy for colorectal liver metastases. J Gastrointest Surg 2017; 21: 68-77.
    • (2017) J Gastrointest Surg , vol.21 , pp. 68-77
    • Denbo, J.W.1    Yamashita, S.2    Passot, G.3
  • 19
    • 84959934892 scopus 로고    scopus 로고
    • Predictors of safety and efficacy of 2-stage hepatectomy for bilateral colorectal liver metastases
    • Passot G, Chun YS, Kopetz SE,. Predictors of safety and efficacy of 2-stage hepatectomy for bilateral colorectal liver metastases. J Am Coll Surg 2016; 223: 99-108.
    • (2016) J Am Coll Surg , vol.223 , pp. 99-108
    • Passot, G.1    Chun, Y.S.2    Kopetz, S.E.3
  • 20
    • 84908573757 scopus 로고    scopus 로고
    • FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): A randomised, open-label, phase 3 trial
    • Heinemann V, von Weikersthal LF, Decker T,. FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial. Lancet Oncol 2014; 15: 1065-1075.
    • (2014) Lancet Oncol , vol.15 , pp. 1065-1075
    • Heinemann, V.1    Von Weikersthal, L.F.2    Decker, T.3
  • 21
    • 84995790077 scopus 로고    scopus 로고
    • Impact of somatic mutations on patterns of metastasis in colorectal cancer
    • Lipsyc M, Yaeger R,. Impact of somatic mutations on patterns of metastasis in colorectal cancer. J Gastrointest Oncol 2015; 6: 645-649.
    • (2015) J Gastrointest Oncol , vol.6 , pp. 645-649
    • Lipsyc, M.1    Yaeger, R.2
  • 22
    • 84893461612 scopus 로고    scopus 로고
    • PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer: Results from NCIC CTG/AGITG CO.17
    • Karapetis CS, Jonker D, Daneshmand M,. PIK3CA, BRAF, and PTEN status and benefit from cetuximab in the treatment of advanced colorectal cancer: results from NCIC CTG/AGITG CO.17. Clin Cancer Res 2014; 20: 744-753.
    • (2014) Clin Cancer Res , vol.20 , pp. 744-753
    • Karapetis, C.S.1    Jonker, D.2    Daneshmand, M.3
  • 23
    • 79952702311 scopus 로고    scopus 로고
    • KRAS mutation analysis: A comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients
    • Knijn N, Mekenkamp LJ, Klomp M,. KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients. Br J Cancer 2011; 104: 1020-1026.
    • (2011) Br J Cancer , vol.104 , pp. 1020-1026
    • Knijn, N.1    Mekenkamp, L.J.2    Klomp, M.3
  • 24
    • 84929359174 scopus 로고    scopus 로고
    • Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era
    • Kim R, Schell MJ, Teer JK,. Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era. PLoS One 2015; 10: e0126670.
    • (2015) PLoS One , vol.10
    • Kim, R.1    Schell, M.J.2    Teer, J.K.3
  • 25
    • 80053198693 scopus 로고    scopus 로고
    • Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: A review
    • Baas JM, Krens LL, Guchelaar HJ,. Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: a review. Oncologist 2011; 16: 1239-1249.
    • (2011) Oncologist , vol.16 , pp. 1239-1249
    • Baas, J.M.1    Krens, L.L.2    Guchelaar, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.