메뉴 건너뛰기




Volumn 22, Issue 3, 2015, Pages 834-842

RAS Mutations Predict Radiologic and Pathologic Response in Patients Treated with Chemotherapy Before Resection of Colorectal Liver Metastases

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; FLUOROURACIL; IRINOTECAN; OXALIPLATIN; ANTINEOPLASTIC AGENT; GUANOSINE TRIPHOSPHATASE; KRAS PROTEIN, HUMAN; MEMBRANE PROTEIN; NRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN;

EID: 84924934023     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-014-4042-6     Document Type: Article
Times cited : (92)

References (37)
  • 1
    • 68949094312 scopus 로고    scopus 로고
    • Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
    • PID: 19470929
    • Kopetz S, Chang GJ, Overman MJ, et al. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol. 2009;27(22):3677–83.
    • (2009) J Clin Oncol. , vol.27 , Issue.22 , pp. 3677-3683
    • Kopetz, S.1    Chang, G.J.2    Overman, M.J.3
  • 2
    • 40749107362 scopus 로고    scopus 로고
    • Perioperative chemotherapy for resectable hepatic metastases
    • PID: 18358910
    • Kopetz S, Vauthey JN. Perioperative chemotherapy for resectable hepatic metastases. Lancet. 2008;371(9617):963–5.
    • (2008) Lancet. , vol.371 , Issue.9617 , pp. 963-965
    • Kopetz, S.1    Vauthey, J.N.2
  • 3
    • 0033504042 scopus 로고    scopus 로고
    • Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases
    • COI: 1:STN:280:DyaK1MvitFahsw%3D%3D, PID: 10493478
    • Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg. 1999;230(3):309–18.
    • (1999) Ann Surg. , vol.230 , Issue.3 , pp. 309-318
    • Fong, Y.1    Fortner, J.2    Sun, R.L.3    Brennan, M.F.4    Blumgart, L.H.5
  • 4
    • 0032821469 scopus 로고    scopus 로고
    • Hepatic resection for metastatic colorectal adenocarcinoma: a proposal of a prognostic scoring system
    • COI: 1:STN:280:DyaK1MzpvF2juw%3D%3D, PID: 10472930
    • Iwatsuki S, Dvorchik I, Madariaga JR, et al. Hepatic resection for metastatic colorectal adenocarcinoma: a proposal of a prognostic scoring system. J Am Coll Surg. 1999;189(3):291–9.
    • (1999) J Am Coll Surg. , vol.189 , Issue.3 , pp. 291-299
    • Iwatsuki, S.1    Dvorchik, I.2    Madariaga, J.R.3
  • 5
    • 0029881854 scopus 로고    scopus 로고
    • Surgical resection of colorectal carcinoma metastases to the liver. A prognostic scoring system to improve case selection, based on 1568 patients. Association Francaise de Chirurgie
    • COI: 1:STN:280:DyaK287pslCiuw%3D%3D, PID: 8608500
    • Nordlinger B, Guiguet M, Vaillant JC, et al. Surgical resection of colorectal carcinoma metastases to the liver. A prognostic scoring system to improve case selection, based on 1568 patients. Association Francaise de Chirurgie. Cancer. 1996;77(7):1254–62.
    • (1996) Cancer. , vol.77 , Issue.7 , pp. 1254-1262
    • Nordlinger, B.1    Guiguet, M.2    Vaillant, J.C.3
  • 6
    • 37549016003 scopus 로고    scopus 로고
    • Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients
    • PID: 18156932
    • Rees M, Tekkis PP, Welsh FK, O’Rourke T, John TG. Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients. Ann Surg. 2008;247(1):125–35.
    • (2008) Ann Surg. , vol.247 , Issue.1 , pp. 125-135
    • Rees, M.1    Tekkis, P.P.2    Welsh, F.K.3    O’Rourke, T.4    John, T.G.5
  • 7
    • 80052751469 scopus 로고    scopus 로고
    • Clinical scoring systems for stratifying risk after resection of hepatic colorectal metastases: still relevant?
    • PID: 21638091
    • Jarnagin WR. Clinical scoring systems for stratifying risk after resection of hepatic colorectal metastases: still relevant? Ann Surg Oncol. 2011;18(10):2711–3.
    • (2011) Ann Surg Oncol. , vol.18 , Issue.10 , pp. 2711-2713
    • Jarnagin, W.R.1
  • 8
    • 35648981122 scopus 로고    scopus 로고
    • Actual 10-year survival after resection of colorectal liver metastases defines cure
    • PID: 17925551
    • Tomlinson JS, Jarnagin WR, DeMatteo RP, et al. Actual 10-year survival after resection of colorectal liver metastases defines cure. J Clin Oncol. 2007;25(29):4575–80.
    • (2007) J Clin Oncol. , vol.25 , Issue.29 , pp. 4575-4580
    • Tomlinson, J.S.1    Jarnagin, W.R.2    DeMatteo, R.P.3
  • 9
    • 56749096759 scopus 로고    scopus 로고
    • Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases
    • PID: 18936472
    • Blazer DG, 3rd, Kishi Y, Maru DM, et al. Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. J Clin Oncol. 2008;26(33):5344–51.
    • (2008) J Clin Oncol. , vol.26 , Issue.33 , pp. 5344-5351
    • Blazer, D.G.1    Kishi, Y.2    Maru, D.M.3
  • 10
    • 72249083700 scopus 로고    scopus 로고
    • Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with bevacizumab for colorectal liver metastases
    • COI: 1:CAS:528:DC%2BD1MXhsFCjsbzP, PID: 19952320
    • Chun YS, Vauthey JN, Boonsirikamchai P, et al. Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with bevacizumab for colorectal liver metastases. JAMA. 2009;302(21):2338–44.
    • (2009) JAMA. , vol.302 , Issue.21 , pp. 2338-2344
    • Chun, Y.S.1    Vauthey, J.N.2    Boonsirikamchai, P.3
  • 11
    • 84871802981 scopus 로고    scopus 로고
    • Optimal morphologic response to preoperative chemotherapy: an alternate outcome end point before resection of hepatic colorectal metastases
    • COI: 1:CAS:528:DC%2BC3sXhsFelsrc%3D, PID: 23150701
    • Shindoh J, Loyer EM, Kopetz S, et al. Optimal morphologic response to preoperative chemotherapy: an alternate outcome end point before resection of hepatic colorectal metastases. J Clin Oncol. 2012;30(36):4566–72.
    • (2012) J Clin Oncol. , vol.30 , Issue.36 , pp. 4566-4572
    • Shindoh, J.1    Loyer, E.M.2    Kopetz, S.3
  • 12
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • COI: 1:CAS:528:DyaL2sXktlCht78%3D, PID: 3587348
    • Bos JL, Fearon ER, Hamilton SR, et al. Prevalence of ras gene mutations in human colorectal cancers. Nature. 1987;327(6120):293–7.
    • (1987) Nature. , vol.327 , Issue.6120 , pp. 293-297
    • Bos, J.L.1    Fearon, E.R.2    Hamilton, S.R.3
  • 13
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • COI: 1:STN:280:DyaL1czgt1aqtQ%3D%3D, PID: 2841597
    • Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med. 1988;319(9):525–32.
    • (1988) N Engl J Med. , vol.319 , Issue.9 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 14
    • 0032490124 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: the multicenter “RASCAL” study
    • COI: 1:CAS:528:DyaK1cXjtlSiu7s%3D, PID: 9586664
    • Andreyev HJ, Norman AR, Cunningham D, Oates JR, Clarke PA. Kirsten ras mutations in patients with colorectal cancer: the multicenter “RASCAL” study. J Natl Cancer Inst. 1998;90(9):675–84.
    • (1998) J Natl Cancer Inst. , vol.90 , Issue.9 , pp. 675-684
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3    Oates, J.R.4    Clarke, P.A.5
  • 15
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • COI: 1:CAS:528:DC%2BD3MXjsV2ms74%3D, PID: 11309634
    • Watanabe T, Wu TT, Catalano PJ, et al. Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med. 2001;344(16):1196–206.
    • (2001) N Engl J Med. , vol.344 , Issue.16 , pp. 1196-1206
    • Watanabe, T.1    Wu, T.T.2    Catalano, P.J.3
  • 16
    • 77955277111 scopus 로고    scopus 로고
    • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
    • PID: 20619739
    • De Roock W, Claes B, Bernasconi D, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol. 2010;11(8):753–62.
    • (2010) Lancet Oncol. , vol.11 , Issue.8 , pp. 753-762
    • De Roock, W.1    Claes, B.2    Bernasconi, D.3
  • 17
    • 33646228635 scopus 로고    scopus 로고
    • KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
    • COI: 1:CAS:528:DC%2BD28XjsFSlsb0%3D, PID: 16618717
    • Lievre A, Bachet JB, Le Corre D, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res. 2006;66(8):3992–5.
    • (2006) Cancer Res. , vol.66 , Issue.8 , pp. 3992-3995
    • Lievre, A.1    Bachet, J.B.2    Le Corre, D.3
  • 18
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • PID: 19339720
    • Van Cutsem E, Kohne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 2009;360(14):1408–17.
    • (2009) N Engl J Med. , vol.360 , Issue.14 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 19
    • 77149163487 scopus 로고    scopus 로고
    • KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases
    • PID: 19727962
    • Nash GM, Gimbel M, Shia J, et al. KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases. Ann Surg Oncol. 2010;17(2):572–8.
    • (2010) Ann Surg Oncol. , vol.17 , Issue.2 , pp. 572-578
    • Nash, G.M.1    Gimbel, M.2    Shia, J.3
  • 20
    • 84867085917 scopus 로고    scopus 로고
    • KRAS status and outcome of liver resection after neoadjuvant chemotherapy including bevacizumab
    • COI: 1:CAS:528:DC%2BC38XhsVeitbvI, PID: 23027075
    • Stremitzer S, Stift J, Gruenberger B, et al. KRAS status and outcome of liver resection after neoadjuvant chemotherapy including bevacizumab. Br J Surg. 2012;99(11):1575–82.
    • (2012) Br J Surg. , vol.99 , Issue.11 , pp. 1575-1582
    • Stremitzer, S.1    Stift, J.2    Gruenberger, B.3
  • 21
    • 84879124807 scopus 로고    scopus 로고
    • Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy
    • PID: 23426338
    • Andreou A, Aloia TA, Brouquet A, et al. Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy. Ann Surg. 2013;257(6):1079–88.
    • (2013) Ann Surg. , vol.257 , Issue.6 , pp. 1079-1088
    • Andreou, A.1    Aloia, T.A.2    Brouquet, A.3
  • 22
    • 51049118140 scopus 로고    scopus 로고
    • An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
    • COI: 1:CAS:528:DC%2BD1cXpt1SqtLs%3D, PID: 18676830
    • Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, et al. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. Cancer Res. 2008;68(15):6084–91.
    • (2008) Cancer Res. , vol.68 , Issue.15 , pp. 6084-6091
    • Stemke-Hale, K.1    Gonzalez-Angulo, A.M.2    Lluch, A.3
  • 23
    • 59649090821 scopus 로고    scopus 로고
    • Tabbaa D. SNP genotyping using the Sequenom MassARRAY iPLEX platform. Curr Protoc Hum Genet
    • Gabriel S, Ziaugra L, Tabbaa D. SNP genotyping using the Sequenom MassARRAY iPLEX platform. Curr Protoc Hum Genet. 2009;Chapter 2(Unit 2):12.
    • (2009) Chapter , vol.2 , Issue.Unit 2 , pp. 12
    • Gabriel, S.1    Ziaugra, L.2
  • 24
    • 33847293670 scopus 로고    scopus 로고
    • High-throughput oncogene mutation profiling in human cancer
    • COI: 1:CAS:528:DC%2BD2sXitVOktrs%3D, PID: 17293865
    • Thomas RK, Baker AC, Debiasi RM, et al. High-throughput oncogene mutation profiling in human cancer. Nat Genet. 2007;39(3):347–51.
    • (2007) Nat Genet. , vol.39 , Issue.3 , pp. 347-351
    • Thomas, R.K.1    Baker, A.C.2    Debiasi, R.M.3
  • 25
    • 84924947800 scopus 로고    scopus 로고
    • ® System. 2011
    • ® System. 2011http://www.nature.com/app_notes/nmeth/2010/101304/full/an7545.html.
  • 26
    • 57849117384 scopus 로고    scopus 로고
    • New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)
    • COI: 1:STN:280:DC%2BD1M%2Fgs12rug%3D%3D, PID: 19097774
    • Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 2009;45(2):228–47.
    • (2009) Eur J Cancer. , vol.45 , Issue.2 , pp. 228-247
    • Eisenhauer, E.A.1    Therasse, P.2    Bogaerts, J.3
  • 27
    • 33847333193 scopus 로고    scopus 로고
    • Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery
    • COI: 1:STN:280:DC%2BD2s%2Fotlagsw%3D%3D, PID: 17060484
    • Rubbia-Brandt L, Giostra E, Brezault C, et al. Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery. Ann Oncol. 2007;18(2):299–304.
    • (2007) Ann Oncol. , vol.18 , Issue.2 , pp. 299-304
    • Rubbia-Brandt, L.1    Giostra, E.2    Brezault, C.3
  • 28
    • 84867400489 scopus 로고    scopus 로고
    • Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome
    • PID: 22476753
    • Poultsides GA, Bao F, Servais EL, et al. Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome. Ann Surg Oncol. 2012;19(9):2797–804.
    • (2012) Ann Surg Oncol. , vol.19 , Issue.9 , pp. 2797-2804
    • Poultsides, G.A.1    Bao, F.2    Servais, E.L.3
  • 29
    • 73249130298 scopus 로고    scopus 로고
    • Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
    • COI: 1:CAS:528:DC%2BC3cXjslKrsA%3D%3D, PID: 19942479
    • Folprecht G, Gruenberger T, Bechstein WO, et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol. 2010;11(1):38–47.
    • (2010) Lancet Oncol. , vol.11 , Issue.1 , pp. 38-47
    • Folprecht, G.1    Gruenberger, T.2    Bechstein, W.O.3
  • 30
    • 84884493477 scopus 로고    scopus 로고
    • RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases
    • Vauthey JN, Zimmitti G, Kopetz SE, et al. RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases. Ann Surg. 2013;258(4):619–27.
    • (2013) Ann Surg , vol.258 , Issue.4 , pp. 619-627
    • Vauthey, J.N.1    Zimmitti, G.2    Kopetz, S.E.3
  • 31
    • 84902152754 scopus 로고    scopus 로고
    • Metabolic response to preoperative chemotherapy predicts prognosis for patients undergoing surgical resection of colorectal cancer metastatic to the liver
    • PID: 24595797
    • Lau LF, Williams DS, Lee ST, et al. Metabolic response to preoperative chemotherapy predicts prognosis for patients undergoing surgical resection of colorectal cancer metastatic to the liver. Ann Surg Oncol. 2014;21(7):2420–8.
    • (2014) Ann Surg Oncol. , vol.21 , Issue.7 , pp. 2420-2428
    • Lau, L.F.1    Williams, D.S.2    Lee, S.T.3
  • 32
    • 84891516390 scopus 로고    scopus 로고
    • Use of early tumor shrinkage to predict long-term outcome in metastatic colorectal cancer treated with cetuximab
    • COI: 1:CAS:528:DC%2BC3sXhvVWgtrvO, PID: 24043732
    • Piessevaux H, Buyse M, Schlichting M, et al. Use of early tumor shrinkage to predict long-term outcome in metastatic colorectal cancer treated with cetuximab. J Clin Oncol. 2013;31(30):3764–75.
    • (2013) J Clin Oncol. , vol.31 , Issue.30 , pp. 3764-3775
    • Piessevaux, H.1    Buyse, M.2    Schlichting, M.3
  • 33
    • 58749102224 scopus 로고    scopus 로고
    • High concordance of KRAS status between primary colorectal tumors and related metastatic sites: implications for clinical practice
    • COI: 1:CAS:528:DC%2BD1MXhvV2nurg%3D, PID: 19056857
    • Santini D, Loupakis F, Vincenzi B, et al. High concordance of KRAS status between primary colorectal tumors and related metastatic sites: implications for clinical practice. Oncologist. 2008;13(12):1270–5.
    • (2008) Oncologist. , vol.13 , Issue.12 , pp. 1270-1275
    • Santini, D.1    Loupakis, F.2    Vincenzi, B.3
  • 34
    • 79952702311 scopus 로고    scopus 로고
    • KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients
    • COI: 1:CAS:528:DC%2BC3MXjsVCktbo%3D, PID: 21364579
    • Knijn N, Mekenkamp LJ, Klomp M, et al. KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients. Br J Cancer. 2011;104(6):1020–6.
    • (2011) Br J Cancer. , vol.104 , Issue.6 , pp. 1020-1026
    • Knijn, N.1    Mekenkamp, L.J.2    Klomp, M.3
  • 35
    • 77952092674 scopus 로고    scopus 로고
    • KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications
    • PID: 20049644
    • Italiano A, Hostein I, Soubeyran I, et al. KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications. Ann Surg Oncol. 2010;17(5):1429–34.
    • (2010) Ann Surg Oncol. , vol.17 , Issue.5 , pp. 1429-1434
    • Italiano, A.1    Hostein, I.2    Soubeyran, I.3
  • 36
    • 51049092984 scopus 로고    scopus 로고
    • K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy
    • COI: 1:CAS:528:DC%2BD1cXpt1ejtbg%3D, PID: 18676755
    • Etienne-Grimaldi MC, Formento JL, Francoual M, et al. K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. Clin Cancer Res. 2008;14(15):4830–5.
    • (2008) Clin Cancer Res. , vol.14 , Issue.15 , pp. 4830-4835
    • Etienne-Grimaldi, M.C.1    Formento, J.L.2    Francoual, M.3
  • 37
    • 0025889018 scopus 로고
    • Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver
    • COI: 1:STN:280:DyaK38%2FntFSmtA%3D%3D, PID: 1959991
    • Oudejans JJ, Slebos RJ, Zoetmulder FA, Mooi WJ, Rodenhuis S. Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver. Int J Cancer. 1991;49(6):875–9.
    • (1991) Int J Cancer. , vol.49 , Issue.6 , pp. 875-879
    • Oudejans, J.J.1    Slebos, R.J.2    Zoetmulder, F.A.3    Mooi, W.J.4    Rodenhuis, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.