Necroptosis Execution Is Mediated by Plasma Membrane Nanopores Independent of Calcium

Cell Reports

Volumn 19, Issue 1, 2017, Pages 175-187

  Ros, Uris ^a   Peña Blanco, Aida ^a   Hänggi, Kay ^b   Kunzendorf, Ulrich ^c   Krautwald, Stefan ^c   Wong, W Wei Lynn ^b   García Sáez, Ana J ^a,d  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d MAX PLANCK INSTITUTE FOR INTELLIGENT SYSTEMS   (Germany)

Author keywords

calcium signaling; membrane pores; necroptosis; Smac mimetics; TNF

Indexed keywords

CALCIUM; ENZYME INHIBITOR; MIXED LINEAGE KINASE DOMAIN LIKE; NECROSTATIN 1; PROPIDIUM IODIDE; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN KINASE 3; RECEPTOR INTERACTING PROTEIN KINASE1; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; DIABLO PROTEIN, HUMAN; MAP KINASE KINASE KINASE 7; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; TLR3 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL DISRUPTION; CELL MEMBRANE; CELL PERMEABILIZATION; CONTROLLED STUDY; MOUSE; NANOPORE; NECROPTOSIS; NONHUMAN; OSMOSIS; OSMOTIC PRESSURE; ANIMAL; APOPTOSIS; BIOMIMETICS; HEK293 CELL LINE; HT-29 CELL LINE; HUMAN; METABOLISM; NECROSIS; NIH 3T3 CELL LINE; PATHOLOGY; REPERFUSION INJURY;

ANIMALS; APOPTOSIS; BIOMIMETICS; CALCIUM; CELL MEMBRANE; HEK293 CELLS; HT29 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE KINASES; MICE; MITOCHONDRIAL PROTEINS; NANOPORES; NECROSIS; NIH 3T3 CELLS; OSMOSIS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; REPERFUSION INJURY; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85016964802     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.03.024     Document Type: Article

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