One-Step Microfluidic Synthesis of Nanocomplex with Tunable Rigidity and Acid-Switchable Surface Charge for Overcoming Drug Resistance

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Volumn 13, Issue 9, 2017, Pages

  Feng, Qiang ^a,b   Liu, Jianping ^c   Li, Xuanyu ^a,b   Chen, Qinghua ^a   Sun, Jiashu ^a,b   Shi, Xinghua ^a,b   Ding, Baoquan ^a,b   Yu, Haijun ^c   Li, Yaping ^c   Jiang, Xingyu ^a,b  

^a NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

drug delivery; micellar nanocomplex; microfluidics; multidrug resistance; pH sensitive

Indexed keywords

CARDIOVASCULAR SYSTEM; CHEMOTHERAPY; DISEASES; DRUG DELIVERY; DRUG THERAPY; PH SENSORS; RIGIDITY; SURFACE CHARGE; SYNTHESIS (CHEMICAL); TUMORS;

INHIBITION OF TUMOR GROWTH; MICROFLUIDIC SYNTHESIS; MULTIDRUG RESISTANCE; NANOCOMPLEXES; PH SENSITIVE; PH-SENSITIVE COPOLYMERS; POLY(LACTIC-CO-GLYCOLIC ACID); THERAPEUTIC EFFICACY;

MICROFLUIDICS;

ACID; DOXORUBICIN; NANOPARTICLE;

ANIMAL; BAGG ALBINO MOUSE; CELL DEATH; CHEMISTRY; DRUG EFFECT; FEMALE; HUMAN; LYSOSOME; MCF-7 CELL LINE; METABOLISM; MICELLE; MICROFLUIDICS; MULTIDRUG RESISTANCE; PH; PROCEDURES; SURFACE PROPERTY;

ACIDS; ANIMALS; CELL DEATH; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MCF-7 CELLS; MICE, INBRED BALB C; MICELLES; MICROFLUIDICS; NANOPARTICLES; SURFACE PROPERTIES;

EID: 85016614373     PISSN: 16136810     EISSN: 16136829     Source Type: Journal    
DOI: 10.1002/smll.201603109     Document Type: Article

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