Toxicological evaluation of ethanolic extract from Stevia rebaudiana Bertoni leaves: Genotoxicity and subchronic oral toxicity

Regulatory Toxicology and Pharmacology

Volumn 86, Issue , 2017, Pages 253-259

  Zhang, Qiannan ^a   Yang, Hui ^a   Li, Yongning ^a   Liu, Haibo ^a   Jia, Xudong ^a  

^a BEIJING HOSPITAL   (China)

Author keywords

Ethanolic extract; Genotoxicity; Safety evaluation; Stevia rebaudiana Bertoni; Subchronic toxicity

Indexed keywords

ALBUMIN; ALCOHOL; CHOLESTEROL; ISOCHLOROGENIC ACID; PLANT EXTRACT; POLYPHENOL; PROTEIN; STEVIA REBAUDIANA EXTRACT; UNCLASSIFIED DRUG; KAURANE DERIVATIVE; SWEETENING AGENT;

ABSENCE OF SIDE EFFECTS; AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CLINICAL CHEMISTRY; CONTROLLED STUDY; FEMALE; FOOD SAFETY; GENOTOXICITY; HEMATOLOGICAL PARAMETERS; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; KUNMING MOUSE; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MOUSE; MOUSE BONE MARROW MICRONUCLEUS ASSAY; MOUSE SPERM MALFORMATION ASSAY; NONHUMAN; PLANT LEAF; RAT; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SEX DIFFERENCE; SPRAGUE DAWLEY RAT; STEVIA REBAUDIANA; SUBCHRONIC TOXICITY; TOXICITY; TOXICITY ASSAY; TOXICITY TESTING; ANIMAL; CHEMISTRY; MUTAGEN TESTING; PROCEDURES; STEVIA;

ANIMALS; DITERPENES, KAURANE; MUTAGENICITY TESTS; PLANT EXTRACTS; PLANT LEAVES; RATS; STEVIA; SWEETENING AGENTS; TOXICITY TESTS, SUBCHRONIC;

EID: 85016267711     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2017.03.021     Document Type: Article

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