The severity of Plasmodium falciparum infection is associated with transcript levels of var genes encoding endothelial protein C receptor-binding P. falciparum erythrocyte membrane protein 1

Infection and Immunity

Volumn 85, Issue 4, 2017, Pages

  Mkumbaye, Sixbert I ^a   Wang, Christian W ^b   Lyimo, Eric ^c   Jespersen, Jakob S ^b   Manjurano, Alphaxard ^c   Mosha, Jacklin ^c   Kavishe, Reginald A ^a   Mwakalinga, Steven B ^a   Minja, Daniel T R ^c   Lusingu, John P ^c   Theander, Thor G ^b   Lavstsen, Thomas ^b  

^a KILIMANJARO CHRISTIAN MEDICAL UNIVERSITY COLLEGE   (Tanzania)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (Tanzania)

Author keywords

Antigenic variation; Gene expression; Malaria; PfEMP1; Plasmodium falciparum

Indexed keywords

ENDOTHELIAL PROTEIN C RECEPTOR; ERYTHROCYTE MEMBRANE PROTEIN 1; PROTEIN CIDRALPHA1; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; ERYTHROCYTE MEMBRANE PROTEIN 1, PLASMODIUM FALCIPARUM;

ANEMIA; ANTIGENIC VARIATION; ARTICLE; CEREBRAL MALARIA; CHILD; DISEASE SEVERITY; FEMALE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTOZOAL GENETICS; QUANTITATIVE ANALYSIS; TANZANIAN; VAR GENE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFANT; MALARIA, FALCIPARUM; PARASITOLOGY; SEVERITY OF ILLNESS INDEX; TANZANIA;

BIOMARKERS; CHILD; CHILD, PRESCHOOL; GENE EXPRESSION REGULATION; HUMANS; INFANT; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTOZOAN PROTEINS; SEVERITY OF ILLNESS INDEX; TANZANIA; TRANSCRIPTION, GENETIC;

EID: 85016216602     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00841-16     Document Type: Article

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