Severity of retinopathy parallels the degree of parasite sequestration in the eyes and brains of Malawian children with fatal cerebral malaria

Journal of Infectious Diseases

Volumn 211, Issue 12, 2015, Pages 1977-1986

  Barrera, Valentina ^a   Hiscott, Paul Stephenson ^a   Craig, Alister Gordon ^b   White, Valerie Ann ^d,e   Milner, Danny Arnold ^f,g   Beare, Nicholas Alexander Venton ^a,c   MacCormick, Ian James Callum ^a,i   Kamiza, Steve ^d   Taylor, Terrie Ellen ^h,i   Molyneux, Malcolm Edward ^b,g   Harding, Simon Peter ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^c ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^d Department of Pathology and Laboratory Medicine ^*  (United Kingdom)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f Brigham and Women's Hospital   (United Kingdom)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^h MICHIGAN STATE UNIVERSITY   (United States)

ⁱ UNIVERSITY OF MALAWI   (Malawi)

Author keywords

cerebral malaria; clinicopathological correlation; histopathology; malarial retinopathy; microvascular congestion; neurovasculature; parasite sequestration; pediatric coma; Plasmodium falciparum malaria; vascular pathology

Indexed keywords

HEMOZOIN;

ARTERIOLE; ARTICLE; AUTOPSY; BRAIN BLOOD VESSEL; BRAIN MALARIA; CAPILLARY; CAUSE OF DEATH; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ERYTHROCYTE; EYE EXAMINATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALARIAL RETINOPATHY; MALAWIAN; NEUROECTODERM; NONHUMAN; OCULAR BLOOD VESSEL; PARASITE LOAD; PARASITE MATURITY; PARASITE PHENOMENA AND FUNCTIONS; PARASITE SEQUESTRATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; RETINA; RETINOPATHY; VENULE; BRAIN; COMPLICATION; CYTOCHEMISTRY; EYE DISEASE; FEMALE; INFANT; ISOLATION AND PURIFICATION; MALARIA; MALARIA FALCIPARUM; MALAWI; MALE; NEWBORN; PARASITOLOGY; PATHOLOGY; PRESCHOOL CHILD;

BRAIN; CHILD; CHILD, PRESCHOOL; EYE DISEASES; FEMALE; HISTOCYTOCHEMISTRY; HUMANS; INFANT; INFANT, NEWBORN; MALARIA, CEREBRAL; MALARIA, FALCIPARUM; MALAWI; MALE; PARASITE LOAD; PLASMODIUM FALCIPARUM; RETINA;

EID: 84930344024     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu592     Document Type: Article

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