Dynamic convergent evolution drives the passage adaptation across 48 years' history of H3N2 influenza evolution

Molecular Biology and Evolution

Volumn 33, Issue 12, 2016, Pages 3133-3143

  Chen, Hui ^a   Deng, Qiang ^a,b,c   Ng, Sock Hoon ^d   Lee, Raphael Tze Chuen ^e   Maurer Stroh, Sebastian ^e,f,g,h   Zhai, Weiwei ^a  

^a GENOME INSTITUTE OF SINGAPORE   (Singapore)

^b Chinese Academy of Sciences   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d DSO NATIONAL LABORATORIES   (Singapore)

^e BIOINFORMATICS INSTITUTE   (Singapore)

^f NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^g MINISTRY OF HEALTH   (Singapore)

^h NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Adaptive evolution; Convergent evolution; Embryonated egg; Host mediated changes; Influenza H3N2; Mutational mapping; Passage adaptation; Vaccine production

Indexed keywords

EPITOPE; CODON; INFLUENZA VIRUS HEMAGGLUTININ;

ARTICLE; CODON; CONTROLLED STUDY; CONVERGENT EVOLUTION; EVOLUTIONARY ADAPTATION; INFLUENZA A VIRUS (H3N2); MAMMAL CELL; NONHUMAN; PHYLOGENY; RECEPTOR BINDING; SEQUENCE ANALYSIS; ZYGOTE; ADAPTATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHICK EMBRYO; DNA SEQUENCE; EVOLUTION; GENETICS; HUMAN; INFLUENZA; MOLECULAR EVOLUTION; PROCEDURES; STRUCTURE ACTIVITY RELATION; VIROLOGY;

ADAPTATION, PHYSIOLOGICAL; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL EVOLUTION; CELL LINE; CHICK EMBRYO; CODON; EVOLUTION, MOLECULAR; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA, HUMAN; PHYLOGENY; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85016211242     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msw190     Document Type: Article

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