Phylodynamics of H1N1/2009 influenza reveals the transition from host adaptation to immune-driven selection

Nature Communications

Volumn 6, Issue , 2015, Pages

  Su, Yvonne C F ^a   Bahl, Justin ^a,b   Joseph, Udayan ^a   Butt, Ka Man ^a   Peck, Heidi A ^c   Koay, Evelyn S C ^d   Oon, Lynette L E ^e   Barr, Ian G ^c   Vijaykrishna, Dhanasekaran ^a,c,f   Smith, Gavin J D ^a,c,g  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^c World Health Organisation Collaborating Centre for Reference Research on Influenza   (Australia)

^d NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^e SINGAPORE GENERAL HOSPITAL   (Singapore)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ANTIGEN; DISEASE TRANSMISSION; EVOLUTIONARY BIOLOGY; GENETIC VARIATION; IMMUNE RESPONSE; INFLUENZA; NATURAL SELECTION; VIRUS;

2009 H1N1 INFLUENZA; ADAPTATION; ANIMAL CELL; ANTIGENICITY; ARTICLE; DYNAMICS; GENETIC VARIABILITY; HUMAN; INVESTIGATIVE PROCEDURES; NATURAL SELECTION; NONHUMAN; PANDEMIC; SEASONAL INFLUENZA; SINGAPORE; ANIMAL; DOG; GENETIC SELECTION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INFLUENZA A VIRUS (H1N1); MDCK CELL LINE; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PHYLOGENY; PHYLOGEOGRAPHY; VIRUS GENOME;

SINGAPORE [SOUTHEAST ASIA];

SUIDAE;

ADAPTATION, BIOLOGICAL; ANIMALS; DOGS; EVOLUTION, MOLECULAR; GENOME, VIRAL; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; MADIN DARBY CANINE KIDNEY CELLS; MOLECULAR SEQUENCE DATA; PANDEMICS; PHYLOGENY; PHYLOGEOGRAPHY; SELECTION, GENETIC;

EID: 84938829022     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8952     Document Type: Article

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