Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials

British Journal of Clinical Pharmacology

Volumn 83, Issue 8, 2017, Pages 1643-1653

  Larsen, Emil List ^a   Cejvanovic, Vanja ^a,b   Kjær, Laura Kofoed ^a,b   Pedersen, Morten Thorup ^a   Popik, Sara Daugaard ^a   Hansen, Lina Kallehave ^a   Andersen, Jon Trærup ^a,b   Jimenez Solem, Espen ^a,b   Broedbaek, Kasper ^a   Petersen, Morten ^a   Weimann, Allan ^a   Henriksen, Trine ^a   Lykkesfeldt, Jens ^b   Torp Pedersen, Christian ^c   Poulsen, Henrik Enghusen ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c AALBORG UNIVERSITY   (Denmark)

Author keywords

8 oxo 7,8 dihydro 2 deoxyguanosine; 8 oxo 7,8 dihydroguanosine; antibiotics; DNA oxidation; oxidative stress; RNA oxidation

Indexed keywords

CLARITHROMYCIN; DEOXYGUANOSINE; MALONALDEHYDE; PENICILLIN V; PLACEBO; TRIMETHOPRIM; 8-HYDROXYGUANOSINE; 8-OXO-7-HYDRODEOXYGUANOSINE; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER; DNA; GUANOSINE; REACTIVE OXYGEN METABOLITE; RNA;

ADULT; ADVERSE DRUG REACTION; ARTICLE; BODY MASS; CAUCASIAN; COMPARATIVE STUDY; DENMARK; DNA MODIFICATION; DNA OXIDATION; DRUG EXCRETION; DRUG MECHANISM; HUMAN; HUMAN EXPERIMENT; INTRACELLULAR SPACE; LIPID PEROXIDATION; MALE; NORMAL HUMAN; OPEN STUDY; OUTCOME ASSESSMENT; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA OXIDATION; URINARY EXCRETION; ANALOGS AND DERIVATIVES; BLOOD; CHEMISTRY; CONTROLLED STUDY; DRUG EFFECTS; METABOLISM; OXIDATION REDUCTION REACTION; RANDOMIZED CONTROLLED TRIAL; URINE; YOUNG ADULT;

ADULT; ANTI-BACTERIAL AGENTS; BIOMARKERS; CLARITHROMYCIN; DEOXYGUANOSINE; DNA; GUANOSINE; HEALTHY VOLUNTEERS; HUMANS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PENICILLIN V; PLACEBOS; REACTIVE OXYGEN SPECIES; RNA; TRIMETHOPRIM; YOUNG ADULT;

EID: 85016207441     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.13261     Document Type: Article

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