Role of epithelial-mesenchymal transition (EMT) and fibroblast function in cerium oxide nanoparticles-induced lung fibrosis

Toxicology and Applied Pharmacology

Volumn 323, Issue , 2017, Pages 16-25

  Ma, Jane ^a   Bishoff, Bridget ^b   Mercer, R R ^a   Barger, Mark ^a   Schwegler Berry, Diane ^a   Castranova, Vincent ^c  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b Formulation Development Services   (India)

^c WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Cerium oxide; Epithelial cells; Epithelial mesenchymal transition; Lung fibrosis; Nanoparticles

Indexed keywords

ALPHA TUBULIN; CERIUM OXIDE NANOPARTICLE; COLLAGEN; HYDROXYPROLINE; SURFACTANT PROTEIN C; TRANSFORMING GROWTH FACTOR BETA1; ACTIN; CERIC OXIDE; CERIUM; METAL NANOPARTICLE; PEPTIDE; SFTPC PROTEIN, RAT; SMOOTH MUSCLE ACTIN, RAT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRONCHOALVEOLAR LAVAGE FLUID; CELL AGGREGATION; CELL FUNCTION; CELL HYPERPLASIA; CELL PROLIFERATION; CELL STRESS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; EPITHELIAL MESENCHYMAL TRANSITION; HYPERTROPHY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL TYPE 2; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG INJURY; LUNG PARENCHYMA; MALE; NANOTOXICOLOGY; NONHUMAN; PROTEIN EXPRESSION; RAT; SIRIUS RED STAINING; STAINING; ANIMAL; CELL CULTURE; CELL SHAPE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; FIBROBLAST; LUNG; LUNG ALVEOLUS EPITHELIUM CELL; METABOLISM; PATHOLOGY; RISK ASSESSMENT; SPRAGUE DAWLEY RAT; STRESS FIBER; TIME FACTOR;

ACTINS; ALVEOLAR EPITHELIAL CELLS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL SHAPE; CELLS, CULTURED; CERIUM; COLLAGEN; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROBLASTS; HYDROXYPROLINE; LUNG; MALE; METAL NANOPARTICLES; PEPTIDES; PULMONARY FIBROSIS; RATS, SPRAGUE-DAWLEY; RISK ASSESSMENT; STRESS FIBERS; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 85016055730     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2017.03.015     Document Type: Article

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