메뉴 건너뛰기




Volumn , Issue , 2003, Pages 181-203

The role of flaxseed lignans in hormone-dependent and independent cancer

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85015578923     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (26)

References (98)
  • 1
    • 0031936568 scopus 로고    scopus 로고
    • Evolution, nutrition, intestinal microflora, and prevention of cancer: A hypothesis
    • Adlercreutz, H. (1998). Evolution, nutrition, intestinal microflora, and prevention of cancer: A hypothesis. Proc. Soc. Exp. Biol. Med. 217, 241-246.
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.217 , pp. 241-246
    • Adlercreutz, H.1
  • 3
    • 0022880001 scopus 로고
    • Determination of urinary lignans and phytoestrogens metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets
    • Adlercreutz, H., Fotsis, T., Bannwart, C., Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1986). Determination of urinary lignans and phytoestrogens metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. J. Steroid Biochem. 25, 791-797.
    • (1986) J. Steroid Biochem. , vol.25 , pp. 791-797
    • Adlercreutz, H.1    Fotsis, T.2    Bannwart, C.3    Wähälä, K.4    Mäkelä, T.5    Brunow, G.6    Hase, T.7
  • 4
    • 0020414806 scopus 로고
    • Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer
    • Adlercreutz, H., Fotsis, T., Heikkinen, R., Dwyer, J.T., Woods, M., Goldin, B.R., and Gorbach, S.L. (1982). Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Lancet ii, 1295-1299.
    • (1982) Lancet , vol.2 , pp. 1295-1299
    • Adlercreutz, H.1    Fotsis, T.2    Heikkinen, R.3    Dwyer, J.T.4    Woods, M.5    Goldin, B.R.6    Gorbach, S.L.7
  • 5
    • 0027325608 scopus 로고
    • Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass spectrometry
    • Adlercreutz, H., Fotsis, T., Lampe, J., Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1993b). Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass spectrometry. Scand. J. Clin. Lab. Invest. 53, 5-18.
    • (1993) Scand. J. Clin. Lab. Invest. , vol.53 , pp. 5-18
    • Adlercreutz, H.1    Fotsis, T.2    Lampe, J.3    Wähälä, K.4    Mäkelä, T.5    Brunow, G.6    Hase, T.7
  • 6
    • 0019189266 scopus 로고
    • Biliary excretion and intestinal metabolism of progesterone and estrogens in man
    • Adlercreutz, H., and Martin, F. (1980). Biliary excretion and intestinal metabolism of progesterone and estrogens in man. J. Steroid Biochem. 13, 231-244.
    • (1980) J. Steroid Biochem. , vol.13 , pp. 231-244
    • Adlercreutz, H.1    Martin, F.2
  • 7
    • 0030976331 scopus 로고    scopus 로고
    • Phyto-oestrogens and Western diseases
    • Adlercreutz, H., and Mazur, W. (1997). Phyto-oestrogens and Western diseases. Ann Med 29, 95-120.
    • (1997) Ann Med , vol.29 , pp. 95-120
    • Adlercreutz, H.1    Mazur, W.2
  • 11
    • 0019217996 scopus 로고
    • Conjugation of lignans in human urine
    • Axelson, M., and Setchell, K.D.R. (1980). Conjugation of lignans in human urine. FEBS Lett. 122, 49-53.
    • (1980) FEBS Lett. , vol.122 , pp. 49-53
    • Axelson, M.1    Setchell, K.D.R.2
  • 12
    • 0019395189 scopus 로고
    • The excretion of lignans in rats - evidence for an intestinal bacterial source for this new group of compounds
    • Axelson, M., and Setchell, K.D.R. (1981). The excretion of lignans in rats - evidence for an intestinal bacterial source for this new group of compounds. FEBS Lett. 123, 337-342.
    • (1981) FEBS Lett. , vol.123 , pp. 337-342
    • Axelson, M.1    Setchell, K.D.R.2
  • 13
    • 0020026453 scopus 로고
    • Origin of lignans in mammals and identification of a precursor from plants
    • Axelson, M., Sjövall, J., Gustaisson, B.E., and Setchell, K.D.R. (1982). Origin of lignans in mammals and identification of a precursor from plants. Nature 298, 659-670.
    • (1982) Nature , vol.298 , pp. 659-670
    • Axelson, M.1    Sjövall, J.2    Gustaisson, B.E.3    Setchell, K.D.R.4
  • 17
    • 0028946787 scopus 로고
    • Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: Relationship to peroxides and vitamin E
    • Chajes, V., Sattler, W., Stranzl, A., and Kostner, G.M. (1995). Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: Relationship to peroxides and vitamin E. Breast Cancer Res. Treat. 34, 199-212.
    • (1995) Breast Cancer Res. Treat. , vol.34 , pp. 199-212
    • Chajes, V.1    Sattler, W.2    Stranzl, A.3    Kostner, G.M.4
  • 18
    • 85036689237 scopus 로고    scopus 로고
    • Lignans and tamoxifen, alone and in combination, inhibit the invasion and adhesion of metastatic human breast cancer cells in vitro
    • Chen, J., and Thompson, L.U. (1999). Lignans and tamoxifen, alone and in combination, inhibit the invasion and adhesion of metastatic human breast cancer cells in vitro. Fed. Am. Soc. Exp. Biol. Journal 13, A582.
    • (1999) Fed. Am. Soc. Exp. Biol. Journal , vol.13 , pp. A582
    • Chen, J.1    Thompson, L.U.2
  • 22
    • 0020402776 scopus 로고
    • Identification and quantitative estimation of a lignan in human and bovine semen
    • Dehennin, L., Reiffsteck, A., Jondet, M., and Thibier, M. (1982). Identification and quantitative estimation of a lignan in human and bovine semen. J. Reprod. Fert. 66, 305-309.
    • (1982) J. Reprod. Fert. , vol.66 , pp. 305-309
    • Dehennin, L.1    Reiffsteck, A.2    Jondet, M.3    Thibier, M.4
  • 23
    • 0030339567 scopus 로고    scopus 로고
    • The biochemistry of metastasis
    • Duffy, M. (1996). The biochemistry of metastasis. Adv. Clin. Chem. 32, 135-165.
    • (1996) Adv. Clin. Chem. , vol.32 , pp. 135-165
    • Duffy, M.1
  • 24
    • 0028972676 scopus 로고
    • Inhibition of 5 α-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids
    • Evans, B.A.J., Griffiths, K., and Morton, M.S. (1995). Inhibition of 5 α-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. J. Endocrinol. 147, 295-302.
    • (1995) J. Endocrinol. , vol.147 , pp. 295-302
    • Evans, B.A.J.1    Griffiths, K.2    Morton, M.S.3
  • 25
  • 27
    • 0025670466 scopus 로고
    • Effect of dietary alpha-linolenic acid on growth, metastasis, fatty acid profile and prostaglandin production of two murine mammary adenocarcinomas
    • Fritsche, K.L., and Johnston, P.V. (1990). Effect of dietary alpha-linolenic acid on growth, metastasis, fatty acid profile and prostaglandin production of two murine mammary adenocarcinomas. J. Nutr. 120, 1601-1609.
    • (1990) J. Nutr. , vol.120 , pp. 1601-1609
    • Fritsche, K.L.1    Johnston, P.V.2
  • 28
    • 0029163997 scopus 로고
    • Plant constituents interfering with human sex hormonebinding globulin. Evaluation of a test method and its application to Urtica dioica root extracts
    • Ganßer, D., and Spiteller, G. (1995). Plant constituents interfering with human sex hormonebinding globulin. Evaluation of a test method and its application to Urtica dioica root extracts. Z. Naturforsch. 50c, 98-104.
    • (1995) Z. Naturforsch. , vol.50c , pp. 98-104
    • Ganßer, D.1    Spiteller, G.2
  • 30
    • 0028017856 scopus 로고
    • N-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines
    • Grammatikos, S.I., Subbaiah, P.V., Victor, T.A., and Miller, W.M. (1994). n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines. Br. J. Cancer 70, 219-227.
    • (1994) Br. J. Cancer , vol.70 , pp. 219-227
    • Grammatikos, S.I.1    Subbaiah, P.V.2    Victor, T.A.3    Miller, W.M.4
  • 31
  • 32
    • 0032971262 scopus 로고    scopus 로고
    • Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women
    • Haggans, C.J., Hutchins, A.M., Olson, A.M., Thomas, W., Martini, M.C., and Slavin, J.L. (1999). Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Nutr. Cancer 33, 188-195.
    • (1999) Nutr. Cancer , vol.33 , pp. 188-195
    • Haggans, C.J.1    Hutchins, A.M.2    Olson, A.M.3    Thomas, W.4    Martini, M.C.5    Slavin, J.L.6
  • 33
    • 0025613733 scopus 로고
    • Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1
    • Hirano, T., Fukuoka, K., Oka, K., Naito, T., Hosaka, K., Mitsuhashi, H., and Matsumoto, Y. (1990). Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1. Cancer Invest. 8, 595-602.
    • (1990) Cancer Invest. , vol.8 , pp. 595-602
    • Hirano, T.1    Fukuoka, K.2    Oka, K.3    Naito, T.4    Hosaka, K.5    Mitsuhashi, H.6    Matsumoto, Y.7
  • 34
    • 0028018410 scopus 로고
    • Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells
    • Hirano, T., Gotoh, M., and Oka, K. (1994). Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. Life Sci. 55, 1061-1069.
    • (1994) Life Sci. , vol.55 , pp. 1061-1069
    • Hirano, T.1    Gotoh, M.2    Oka, K.3
  • 36
    • 0030764023 scopus 로고    scopus 로고
    • Case-control study of phytooestrogens and breast cancer
    • Ingram, D., Sanders, K., Kolybaba, M., and Lopez, D. (1997). Case-control study of phytooestrogens and breast cancer. The Lancet 350, 990-994.
    • (1997) The Lancet , vol.350 , pp. 990-994
    • Ingram, D.1    Sanders, K.2    Kolybaba, M.3    Lopez, D.4
  • 37
    • 0033009912 scopus 로고    scopus 로고
    • Flaxseed and lignans increase cecal β-glucuronidase activity in rats
    • Jenab, M., Richard, S.E., Orcheson, L.J., and Thompson, L.U. (1999). Flaxseed and lignans increase cecal β-glucuronidase activity in rats. Nutr. Cancer 33, 154-158.
    • (1999) Nutr. Cancer , vol.33 , pp. 154-158
    • Jenab, M.1    Richard, S.E.2    Orcheson, L.J.3    Thompson, L.U.4
  • 38
    • 0029951809 scopus 로고    scopus 로고
    • The influence of flaxseed and lignans on colon carcinogenesis and β-glucuronidase activity
    • Jenab, M., and Thompson, L.U. (1996). The influence of flaxseed and lignans on colon carcinogenesis and β-glucuronidase activity. Carcinogenesis 17, 1343-1348.
    • (1996) Carcinogenesis , vol.17 , pp. 1343-1348
    • Jenab, M.1    Thompson, L.U.2
  • 39
    • 0029013060 scopus 로고
    • Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets
    • Kirkman, L.M., Lampe, J.W., Campbell, D.R., Martini, M.C., and Slavin, J.L. (1995). Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets. Nutr. Cancer 24, 1-12.
    • (1995) Nutr. Cancer , vol.24 , pp. 1-12
    • Kirkman, L.M.1    Lampe, J.W.2    Campbell, D.R.3    Martini, M.C.4    Slavin, J.L.5
  • 40
    • 0033400047 scopus 로고    scopus 로고
    • Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone
    • Kitts, D.D., Yuan, Y.V., Wijeckremene, A.N., and Thompson, L.U. (1999). Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. Mol. Cell. Biochem. 202, 91-100.
    • (1999) Mol. Cell. Biochem. , vol.202 , pp. 91-100
    • Kitts, D.D.1    Yuan, Y.V.2    Wijeckremene, A.N.3    Thompson, L.U.4
  • 41
    • 0001123244 scopus 로고
    • The isolation of β-hydroxy-β-methylglutaric acid from the seed of flax (Linum usitatissimum)
    • Klosterman, H.J., and Smith, F. (1954). The isolation of β-hydroxy-β-methylglutaric acid from the seed of flax (Linum usitatissimum). J. Am. Chem. Soc. 76, 1229-1230.
    • (1954) J. Am. Chem. Soc. , vol.76 , pp. 1229-1230
    • Klosterman, H.J.1    Smith, F.2
  • 44
    • 0033013574 scopus 로고    scopus 로고
    • Dietary supplementation with secoisolariciresinol diglycoside reduces experimental metastasis of melanoma cells in mice
    • Li, D., Yee, J.A., Thompson, L.U., and Yan, L. (1999). Dietary supplementation with secoisolariciresinol diglycoside reduces experimental metastasis of melanoma cells in mice. Cancer Lett. 142, 91-96.
    • (1999) Cancer Lett. , vol.142 , pp. 91-96
    • Li, D.1    Yee, J.A.2    Thompson, L.U.3    Yan, L.4
  • 45
    • 0024428521 scopus 로고
    • Tamoxifen prolongs luteal phase in premenopausal women but has no effect on the size of uterine fibroids
    • Lumsden, M.A., West, C.P., and Baird, D.T. (1989). Tamoxifen prolongs luteal phase in premenopausal women but has no effect on the size of uterine fibroids. Clin. Endocrinol. (Oxford) 31, 335-343.
    • (1989) Clin. Endocrinol. (Oxford) , vol.31 , pp. 335-343
    • Lumsden, M.A.1    West, C.P.2    Baird, D.T.3
  • 46
    • 0018574160 scopus 로고
    • Two binding sites for estradiol in rat uterine nuclei: Relationship to uterotrophic response
    • Markaverich, B.M., and Clark, J.H. (1979). Two binding sites for estradiol in rat uterine nuclei: relationship to uterotrophic response. Endocrinol. 105, 1458-1462.
    • (1979) Endocrinol. , vol.105 , pp. 1458-1462
    • Markaverich, B.M.1    Clark, J.H.2
  • 48
    • 0001107112 scopus 로고
    • Interactions between phytoestrogens and human sex steroid binding protein
    • Martin, M., Haourigui, M., Pelissero, C., Benassayag, C., and Nunez, E. (1995). Interactions between phytoestrogens and human sex steroid binding protein. Life Science 58, 429-436.
    • (1995) Life Science , vol.58 , pp. 429-436
    • Martin, M.1    Haourigui, M.2    Pelissero, C.3    Benassayag, C.4    Nunez, E.5
  • 49
    • 0030047573 scopus 로고    scopus 로고
    • Isotope dilution gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples
    • Mazur, W., Fotsis, T., Wähälä, K., Ojala, S., Salakka, A., and Adlercreutz, H. (1996). Isotope dilution gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples. Anal. Biochem. 233, 169-180.
    • (1996) Anal. Biochem. , vol.233 , pp. 169-180
    • Mazur, W.1    Fotsis, T.2    Wähälä, K.3    Ojala, S.4    Salakka, A.5    Adlercreutz, H.6
  • 50
    • 0025636191 scopus 로고
    • The significance of steroid metabolism in human cancer
    • Miller, W.R., and O’Neill, J.S. (1989). The significance of steroid metabolism in human cancer. J. Steroid Biochem. Mol. Biol. 37, 317-325.
    • (1989) J. Steroid Biochem. Mol. Biol. , vol.37 , pp. 317-325
    • Miller, W.R.1    O’Neill, J.S.2
  • 52
    • 0027998442 scopus 로고
    • Determination of lignans and isoflavonoids in human female plasma following dietary supplementation
    • Morton, M.S., Wilcox, G., Wahlqvist, M.L., and Griffiths, K. (1994). Determination of lignans and isoflavonoids in human female plasma following dietary supplementation. J. Endocrinol. 142, 251-259.
    • (1994) J. Endocrinol. , vol.142 , pp. 251-259
    • Morton, M.S.1    Wilcox, G.2    Wahlqvist, M.L.3    Griffiths, K.4
  • 53
    • 0026569080 scopus 로고
    • Enterolactone and estradiol inhibit each other’s proliferative effect on MCF-7 breast cancer cells in culture
    • Mousavi, Y., and Adlercreutz, H. (1992). Enterolactone and estradiol inhibit each other’s proliferative effect on MCF-7 breast cancer cells in culture. J. Steroid Biochem. Mol. Biol. 41, 615-619.
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.41 , pp. 615-619
    • Mousavi, Y.1    Adlercreutz, H.2
  • 54
    • 0033005792 scopus 로고    scopus 로고
    • Human metabolism of mammalian lignan precursors in raw and processed flaxseed
    • Nesbitt, P.D., Lam, Y., and Thompson, L.U. (1999). Human metabolism of mammalian lignan precursors in raw and processed flaxseed. Am. J. Clin. Nutr. 69, 549-555.
    • (1999) Am. J. Clin. Nutr. , vol.69 , pp. 549-555
    • Nesbitt, P.D.1    Lam, Y.2    Thompson, L.U.3
  • 55
    • 0031405780 scopus 로고    scopus 로고
    • Lignans in homemade and commercial products containing flaxseed
    • Nesbitt, P.D., and Thompson, L.U. (1997). Lignans in homemade and commercial products containing flaxseed. Nutr. Cancer 29, 222-227.
    • (1997) Nutr. Cancer , vol.29 , pp. 222-227
    • Nesbitt, P.D.1    Thompson, L.U.2
  • 57
    • 0032513184 scopus 로고    scopus 로고
    • Flaxseed and its mammalian lignan precursor cause a lengthening or cessation of estrous cycling in rats
    • Orcheson, L.J., Rickard, S.E., Seidl, M.M., and Thompson, L.U. (1998). Flaxseed and its mammalian lignan precursor cause a lengthening or cessation of estrous cycling in rats. Cancer Lett. 125, 69-76.
    • (1998) Cancer Lett. , vol.125 , pp. 69-76
    • Orcheson, L.J.1    Rickard, S.E.2    Seidl, M.M.3    Thompson, L.U.4
  • 61
    • 0031040390 scopus 로고    scopus 로고
    • Hydroxy radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed
    • Prasad, K. (1997). Hydroxy radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed. Mol. Cell. Biochem. 168, 117-123.
    • (1997) Mol. Cell. Biochem. , vol.168 , pp. 117-123
    • Prasad, K.1
  • 62
    • 0029777340 scopus 로고    scopus 로고
    • Dose-dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed
    • Rickard, S.E., Orcheson, L.J., Seidl, M.M., Luyengi, L., Fong, H.H.S., and Thompson, L.U. (1996). Dose-dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed. J. Nutr. 126, 2012-2019.
    • (1996) J. Nutr. , vol.126 , pp. 2012-2019
    • Rickard, S.E.1    Orcheson, L.J.2    Seidl, M.M.3    Luyengi, L.4    Fong, H.H.S.5    Thompson, L.U.6
  • 63
    • 0002359003 scopus 로고    scopus 로고
    • Phytoestrogens and lignans: Effects on reproduction and chronic disease
    • Shahidi, F. (ed.), ACS, Washington, DC
    • Rickard, S.E., and Thompson, L.U. (1997). Phytoestrogens and lignans: Effects on reproduction and chronic disease. In Shahidi, F. (ed.) Antinutrients and Phytochemicals in Foods, ACS, Washington, DC, pp. 273-293.
    • (1997) Antinutrients and Phytochemicals in Foods , pp. 273-293
    • Rickard, S.E.1    Thompson, L.U.2
  • 64
    • 0031594303 scopus 로고    scopus 로고
    • Chronic exposure to secoisolariciresinol diglycoside alters lignan disposition in rats
    • Rickard, S.E., and Thompson, L.U. (1998). Chronic exposure to secoisolariciresinol diglycoside alters lignan disposition in rats. J. Nutr. 128, 615-623.
    • (1998) J. Nutr. , vol.128 , pp. 615-623
    • Rickard, S.E.1    Thompson, L.U.2
  • 65
    • 0032806446 scopus 로고    scopus 로고
    • Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea (MNU)-induced mammary tumorigenesis in rats
    • Rickard, S.E., Yuan, Y.V., Chen, J., and Thompson, L.U. (1999). Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea (MNU)-induced mammary tumorigenesis in rats. Nutr. Cancer 35, 50-57.
    • (1999) Nutr. Cancer , vol.35 , pp. 50-57
    • Rickard, S.E.1    Yuan, Y.V.2    Chen, J.3    Thompson, L.U.4
  • 66
    • 0029844233 scopus 로고    scopus 로고
    • Mammary gland neoplasia in long-term rodent studies
    • Russo, I.H., and Russo, J. (1996). Mammary gland neoplasia in long-term rodent studies. Environ. Health Perspect. 104, 938-967.
    • (1996) Environ. Health Perspect. , vol.104 , pp. 938-967
    • Russo, I.H.1    Russo, J.2
  • 67
    • 0028280245 scopus 로고
    • Stimulation of pS2 expression by diet-derived compounds
    • Sathyamoorthy, N., Wang, T.T., and Phang, J.M. (1994). Stimulation of pS2 expression by diet-derived compounds. Cancer Res. 54, 957-961.
    • (1994) Cancer Res. , vol.54 , pp. 957-961
    • Sathyamoorthy, N.1    Wang, T.T.2    Phang, J.M.3
  • 68
    • 0025940535 scopus 로고
    • The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis
    • Serraino, M., and Thompson, L.U. (1991). The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Cancer Lett. 60, 135-142.
    • (1991) Cancer Lett. , vol.60 , pp. 135-142
    • Serraino, M.1    Thompson, L.U.2
  • 69
    • 0026576476 scopus 로고
    • The effect of flaxseed supplementation on the initiation and promotional stages of mammary tumorigenesis
    • Serraino, M., and Thompson, L.U. (1992a). The effect of flaxseed supplementation on the initiation and promotional stages of mammary tumorigenesis. Nutr. Cancer 17, 153-159.
    • (1992) Nutr. Cancer , vol.17 , pp. 153-159
    • Serraino, M.1    Thompson, L.U.2
  • 70
    • 0026509247 scopus 로고
    • Flaxseed supplementation and early markers of colon carcinogenesis
    • Serraino, M., and Thompson, L.U. (1992b). Flaxseed supplementation and early markers of colon carcinogenesis. Cancer Lett. 63, 159-165.
    • (1992) Cancer Lett. , vol.63 , pp. 159-165
    • Serraino, M.1    Thompson, L.U.2
  • 71
    • 0026699914 scopus 로고
    • Effect of low level flaxseed supplementation on the fatty acid composition of mammary glands and tumors in rats
    • Serraino, M., Thompson, L.U., and Cunnane, S.C. (1992). Effect of low level flaxseed supplementation on the fatty acid composition of mammary glands and tumors in rats. Nutr. Res. 12, 767-772.
    • (1992) Nutr. Res. , vol.12 , pp. 767-772
    • Serraino, M.1    Thompson, L.U.2    Cunnane, S.C.3
  • 72
    • 0002252168 scopus 로고
    • Discovery and potential clinical importance of mammalian lignans
    • Cunnane, S.C., and Thompson, L.U. (eds), AOCS Press, Champaign, Ill
    • Setchell, K.D.R. (1995). Discovery and potential clinical importance of mammalian lignans. In Cunnane, S.C., and Thompson, L.U. (eds), Flaxseed in Human Nutrition, AOCS Press, Champaign, Ill, pp. 82-98.
    • (1995) Flaxseed in Human Nutrition , pp. 82-98
    • Setchell, K.D.R.1
  • 73
    • 0018857072 scopus 로고
    • Steroid excretion during the reproductive cycle and pregnancy of the velvet monkey (Ceropithecus aethiopus pygerythrus)
    • Setchell, K.D.R., Bull, R., and Adlercreutz, H. (1980a). Steroid excretion during the reproductive cycle and pregnancy of the velvet monkey (Ceropithecus aethiopus pygerythrus). J. Steroid Biochem. 12, 375-384.
    • (1980) J. Steroid Biochem. , vol.12 , pp. 375-384
    • Setchell, K.D.R.1    Bull, R.2    Adlercreutz, H.3
  • 78
    • 0022962911 scopus 로고
    • Quantitation of nuclear aberrations as a screen for agents damaging to mammary epithelium
    • Sharkey, M., and Bruce, R. (1986). Quantitation of nuclear aberrations as a screen for agents damaging to mammary epithelium. Carcinogenesis 7, 1991-1995.
    • (1986) Carcinogenesis , vol.7 , pp. 1991-1995
    • Sharkey, M.1    Bruce, R.2
  • 79
    • 0025789945 scopus 로고
    • Effect of short-term flaxseed consumption of lignan and sex hormone metabolism in men
    • Shultz, T.D., Bonorden, W.R., and Seaman, W.R. (1991). Effect of short-term flaxseed consumption of lignan and sex hormone metabolism in men. Nutr. Res. 11, 1089-1100.
    • (1991) Nutr. Res. , vol.11 , pp. 1089-1100
    • Shultz, T.D.1    Bonorden, W.R.2    Seaman, W.R.3
  • 81
    • 0031829797 scopus 로고    scopus 로고
    • Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells
    • Sung, M.-K., Lautens, M., and Thompson, L.U. (1998). Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells. Anticancer Res. 18, 1405-1408.
    • (1998) Anticancer Res. , vol.18 , pp. 1405-1408
    • Sung, M.-K.1    Lautens, M.2    Thompson, L.U.3
  • 82
    • 0028709601 scopus 로고
    • Antioxidants and hormone-mediated health benefits of whole grains
    • Thompson, L.U. (1994). Antioxidants and hormone-mediated health benefits of whole grains. Crit. Rev. Food Sci. Nutr. 34, 473-497.
    • (1994) Crit. Rev. Food Sci. Nutr. , vol.34 , pp. 473-497
    • Thompson, L.U.1
  • 84
    • 0029902997 scopus 로고    scopus 로고
    • Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis
    • Thompson, L.U., Rickard, S.E., Orcheson, L.J., and Seidl, M.M. (1996a). Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis 17, 1373-1376.
    • (1996) Carcinogenesis , vol.17 , pp. 1373-1376
    • Thompson, L.U.1    Rickard, S.E.2    Orcheson, L.J.3    Seidl, M.M.4
  • 85
  • 87
    • 0030974193 scopus 로고    scopus 로고
    • Endogenous estrogens and breast cancer risk: The case for prospective cohort studies
    • Toniolo, P.G. (1997). Endogenous estrogens and breast cancer risk: The case for prospective cohort studies. Environ. Health Perspect. 105 (Suppl.), 587-592.
    • (1997) Environ. Health Perspect. , vol.105 , pp. 587-592
    • Toniolo, P.G.1
  • 88
    • 0031737636 scopus 로고    scopus 로고
    • Flaxseed and its lignan precursor, secoisolariciresinol diglucoside, affect pregnancy outcome and reproductive development in rats
    • Tou, J.C., Chen, J., and Thompson, L.U. (1998). Flaxseed and its lignan precursor, secoisolariciresinol diglucoside, affect pregnancy outcome and reproductive development in rats. J. Nutr. 128, 1861-1868.
    • (1998) J. Nutr. , vol.128 , pp. 1861-1868
    • Tou, J.C.1    Chen, J.2    Thompson, L.U.3
  • 89
    • 0033597190 scopus 로고    scopus 로고
    • Dose, timing, and duration of flaxseed exposure affect reproductive indices and sex hormone levels in rats
    • Tou, J.C., Chen, J., and Thompson, L.U. (1999). Dose, timing, and duration of flaxseed exposure affect reproductive indices and sex hormone levels in rats. J. Toxicol. Environ. Health 56, 555-570.
    • (1999) J. Toxicol. Environ. Health , vol.56 , pp. 555-570
    • Tou, J.C.1    Chen, J.2    Thompson, L.U.3
  • 90
    • 0032824053 scopus 로고    scopus 로고
    • Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures
    • Tou, J.C.L., and Thompson, L.U. (1999). Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures. Carcinogenesis 20, 1831-1835.
    • (1999) Carcinogenesis , vol.20 , pp. 1831-1835
    • Tou, J.C.L.1    Thompson, L.U.2
  • 91
    • 0030880014 scopus 로고    scopus 로고
    • Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells
    • Wang, C., and Kurzer, M.S. (1997). Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells. Nutr. Cancer 28, 236-247.
    • (1997) Nutr. Cancer , vol.28 , pp. 236-247
    • Wang, C.1    Kurzer, M.S.2
  • 92
    • 0031783890 scopus 로고    scopus 로고
    • Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors
    • Wang, C., and Kurzer, M.S. (1998). Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors. Nutr. Cancer 31, 90-100.
    • (1998) Nutr. Cancer , vol.31 , pp. 90-100
    • Wang, C.1    Kurzer, M.S.2
  • 94
    • 0020457082 scopus 로고
    • Effect of a lignan (HPMF) on RNA synthesis in the rat uterus
    • Waters, A.P., and Knowler, J.T. (1982). Effect of a lignan (HPMF) on RNA synthesis in the rat uterus. J. Reprod. Fertil. 66, 379-381.
    • (1982) J. Reprod. Fertil. , vol.66 , pp. 379-381
    • Waters, A.P.1    Knowler, J.T.2
  • 95
    • 0023551893 scopus 로고
    • Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol
    • Welshons, W.V., Murphy, C.S., Koch, R., Calaf, G., and Jordan, V.C. (1987). Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol. Breast Cancer Res. Treat. 10, 169-175.
    • (1987) Breast Cancer Res. Treat. , vol.10 , pp. 169-175
    • Welshons, W.V.1    Murphy, C.S.2    Koch, R.3    Calaf, G.4    Jordan, V.C.5
  • 96
    • 0001877711 scopus 로고    scopus 로고
    • Variation in the concentration of the flaxseed lignan concentration with variety, location and year
    • Flax Institute of the United States, Fargo, ND
    • Westcott, N.D., and Muir, A.D. (1996). Variation in the concentration of the flaxseed lignan concentration with variety, location and year. In Proc. of the Flax Institute of the United States, Vol. 56, Flax Institute of the United States, Fargo, ND, pp. 77-80.
    • (1996) Proc. of the Flax Institute of the United States , vol.56 , pp. 77-80
    • Westcott, N.D.1    Muir, A.D.2
  • 97
    • 0032570762 scopus 로고    scopus 로고
    • Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice
    • Yan, L., Lee, J.A., Li, D., McGuire, M.H., and Thompson, L.U. (1998). Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice. Cancer Lett. 124, 181-186.
    • (1998) Cancer Lett. , vol.124 , pp. 181-186
    • Yan, L.1    Lee, J.A.2    Li, D.3    McGuire, M.H.4    Thompson, L.U.5
  • 98
    • 0033181054 scopus 로고    scopus 로고
    • Short-term feeding of flaxseed or its lignan has minor influence on in vivo hepatic antioxidant status in young rats
    • Yuan, Y.V., Rickard, S.E., and Thompson, L.U. (1999). Short-term feeding of flaxseed or its lignan has minor influence on in vivo hepatic antioxidant status in young rats. Nutr. Res. 19, 1233-1243.
    • (1999) Nutr. Res. , vol.19 , pp. 1233-1243
    • Yuan, Y.V.1    Rickard, S.E.2    Thompson, L.U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.